EKS-ORA-00267

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORA-00267

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/Alpha	272.7	2.4E-81	27	224	198

Status

Unreviewed

Ensembl Protein

ENSOANP00000005176

UniProt Accession

F6RRE1;

Protein Name

Protein Synonyms/Alias

Gene Name

EEF2K

Gene Synonyms/Alias

EEF2K;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOANG00000003263	ENSOANP00000005176	ENSOANT00000005177

Organism

Ornithorhynchus anatinus

Functional Description

Protein Length

623

Protein Sequence
(FASTA)

MPDPWAEFHL EDIETQCATR HRYNAVTGEW VEDEVLIKMA SKPFGRGAMR ECFRTKKLSN 60

FLHTQHWKGA SNYVAKRYIE PVDREVYFED VRLQMEAKLW GEEFSRHKPP KQVDIMQMCI 120

IELKGRADQP LFHLEHYIEG KYIKYNSNSG FVRDDNIRLT PQAFSHFTFE RSGHQLIVVD 180

IQGVGDLYTD PQIHTEMGTD FGDGNLGVRG MALFFHSHAC NKICKSMNLT PFDLSPKEKD 240

AVNQNTKLLL AQTVVRGTEE KCGSPRVRTF SGSRPPLLFR LSENSGDENM SDVAFDSLPS 300

SPSSATPHSH RLDHLHWPVF NDHDNPDNHR DSENSGDSGY PSEKRSDLED LDHRDKGHSN 360

GNRRQYESDE DSLGSFGRVS VDKWNLYNAS RLHLQRPSCV AGEVQRLNAL DLEKKIGKSI 420

LGKVHLAMVR YHEGGRFCEK DQEWDQESAI FHLEHAADLG ELEAIVGLGL MYSQLPHHIL 480

SDISLEETDE NKMKGFDYLL MAAEAGDRHS MILVARAYDT GLNLGSDRER NWKEALHWYN 540

SALHMTDYDE GGEYDGVQDE PRYLLLAREA AMLMSGGFHL EKDPQRSGDL YTEAAEAAME 600

SMKGRLANEY YQKAEEAWAV MEE 623

Nucleotide Sequence
(FASTA)

ATGCCTGATC CCTGGGCTGA ATTTCATCTT GAGGACATTG AAACACAGTG TGCTACTCGT 60

CACAGGTACA ATGCAGTCAC TGGAGAATGG GTTGAAGATG AGGTCCTCAT CAAAATGGCA 120

TCTAAGCCCT TTGGCCGTGG AGCTATGCGG GAGTGCTTCA GGACGAAAAA ACTGTCTAAC 180

TTCCTGCATA CCCAGCACTG GAAAGGGGCC TCCAACTATG TGGCGAAGCG CTATATTGAA 240

CCCGTGGATA GGGAAGTGTA CTTCGAGGAT GTGCGTCTCC AGATGGAAGC CAAGCTATGG 300

GGAGAGGAAT TTAGCCGACA CAAACCACCC AAGCAGGTTG ATATTATGCA GATGTGCATC 360

ATTGAACTGA AGGGCAGAGC CGACCAGCCC CTGTTTCACC TGGAACATTA CATAGAGGGC 420

AAATACATCA AATACAACTC CAACTCAGGA TTCGTTCGGG ACGACAACAT CCGCCTGACC 480

CCACAGGCTT TTAGCCACTT CACATTTGAG CGCTCGGGTC ATCAGCTGAT TGTGGTGGAT 540

ATTCAAGGCG TGGGAGACCT GTATACAGAC CCTCAGATTC ACACAGAGAT GGGCACAGAC 600

TTCGGAGATG GCAACCTAGG AGTGCGAGGC ATGGCCCTGT TCTTCCATTC CCACGCCTGC 660

AACAAGATCT GCAAGAGCAT GAATCTCACC CCTTTTGACC TCTCTCCCAA GGAAAAGGAT 720

GCCGTGAACC AGAACACAAA GTTGCTGCTG GCTCAGACGG TTGTGCGGGG CACAGAAGAG 780

AAGTGTGGCA GCCCGCGGGT GAGGACGTTC TCTGGAAGTC GGCCCCCTCT GCTTTTCCGC 840

CTCTCGGAGA ATTCAGGAGA CGAGAATATG AGTGATGTAG CATTCGACTC TCTTCCTTCC 900

TCGCCGTCCT CAGCAACACC ACATAGCCAC AGGCTCGACC ACCTTCATTG GCCGGTGTTT 960

AATGACCATG ATAACCCAGA CAACCATAGG GATTCTGAAA ACAGTGGGGA CAGCGGATAC 1020

CCCAGCGAGA AGAGGAGCGA CCTGGAGGAC CTTGATCACC GAGACAAGGG ACATTCAAAC 1080

GGCAACCGGA GGCAGTATGA ATCTGACGAA GACAGTTTGG GAAGCTTTGG AAGGGTCAGT 1140

GTGGATAAGT GGAATCTCTA CAACGCTTCT AGGCTCCACC TCCAGAGGCC ATCCTGTGTT 1200

GCTGGGGAAG TGCAGAGACT TAATGCTCTG GACCTCGAAA AGAAAATCGG AAAGTCCATT 1260

TTGGGGAAGG TTCACCTGGC CATGGTGCGA TACCACGAGG GAGGGCGCTT CTGTGAGAAA 1320

GATCAGGAAT GGGACCAGGA GTCGGCCATC TTTCATCTCG AGCATGCTGC AGATCTGGGG 1380

GAACTGGAGG CCATCGTGGG CCTTGGGCTC ATGTACTCCC AGCTGCCACA CCACATCCTC 1440

TCTGACATCT CTCTGGAGGA GACTGATGAG AACAAGATGA AGGGGTTTGA TTACCTACTA 1500

ATGGCAGCAG AAGCTGGAGA CAGGCACTCC ATGATTCTTG TGGCGCGAGC CTATGATACA 1560

GGCCTGAACC TAGGCTCTGA CAGAGAGCGG AACTGGAAGG AGGCTCTGCA CTGGTACAAC 1620

TCGGCCCTGC ACATGACGGA TTATGACGAA GGGGGCGAGT ACGATGGGGT GCAGGATGAG 1680

CCCCGATACC TGCTCCTGGC AAGAGAGGCT GCGATGCTGA TGAGTGGAGG ATTCCACCTG 1740

GAGAAGGACC CACAGAGATC AGGTGATCTA TACACAGAGG CAGCAGAAGC AGCAATGGAA 1800

TCCATGAAGG GTCGGCTGGC AAATGAATAC TACCAGAAAG CTGAGGAGGC ATGGGCAGTG 1860

ATGGAAGAAT GA 1872

Domain Profile

S: 2     sesWsqqetivlikvlskeekkGalRkalrvkkgslflvkeelkevvryvakiykeqkvl  61

         +++W ++e  vlik++sk++++Ga+R+++r+kk+s+fl+ +++k++++yvak+y+e++++

Q: 27    TGEWVEDE--VLIKMASKPFGRGAMRECFRTKKLSNFLHTQHWKGASNYVAKRYIEPVDR  84

         789*****..**************************************************

S: 62    hlylrdverqraaqklvtefnqvkPkkivyiprlievfLkdrtsknqlltvEeyllGefv  121

         ++y++dv+ q++a+ +++ef ++kP+k+v+i+++++++Lk r  + +l+++E+y++G+++

Q: 85    EVYFEDVRLQMEAKLWGEEFSRHKPPKQVDIMQMCIIELKGRADQ-PLFHLEHYIEGKYI  143

         ********************************************9.**************

S: 122   KynnnngdeikrenkleelmlafsHftyeytngellVvDlqGvgeklTDpqiatksrgtk  181

         Kyn+n+g  ++r+++++ +++afsHft+e+++++l+VvD+qGvg+ +TDpqi+t ++gt+

Q: 144   KYNSNSG--FVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHT-EMGTD  200

         *******..*********************************************.*****

S: 182   fgkanlgeraiknFfakhhCNeiC  205

         fg++nlg+r+++ Ff +h+CN+iC

Q: 201   FGDGNLGVRGMALFFHSHACNKIC  224

         ************************

Domain Sequence
(FASTA)

TGEWVEDEVL IKMASKPFGR GAMRECFRTK KLSNFLHTQH WKGASNYVAK RYIEPVDREV 60

YFEDVRLQME AKLWGEEFSR HKPPKQVDIM QMCIIELKGR ADQPLFHLEH YIEGKYIKYN 120

SNSGFVRDDN IRLTPQAFSH FTFERSGHQL IVVDIQGVGD LYTDPQIHTE MGTDFGDGNL 180

GVRGMALFFH SHACNKIC 198

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0005509	; F:calcium ion binding
GO:0004686	; F:elongation factor-2 kinase activity
GO:0046777	; P:protein autophosphorylation
GO:0031952	; P:regulation of protein autophosphorylation

KEGG

InterPros

IPR017400	; Elongation_factor_2_kinase.
IPR011009	; Kinase-like_dom.
IPR004166	; MHCK_EF2_kinase.
IPR006597	; Sel1-like.
IPR011990	; TPR-like_helical.

Pfam

PF02816	; Alpha_kinase; 1.
PF08238	; Sel1; 4.

SMARTs

SM00811

; Alpha_kinase; 1.

Prosites

PS51158

; ALPHA_KINASE; 1.

Prints

Created Date

20-Feb-2013