EKS-ORA-00360

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORA-00360

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/DAPK	469.2	3.7E-141	1	255	255

Status

Unreviewed

Ensembl Protein

ENSOANP00000005267

UniProt Accession

F7AED4;

Protein Name

Protein Synonyms/Alias

Gene Name

DAPK3

Gene Synonyms/Alias

DAPK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOANG00000003319	ENSOANP00000005267	ENSOANT00000005268

Organism

Ornithorhynchus anatinus

Functional Description

Protein Length

434

Protein Sequence
(FASTA)

SGQFAIVRKC RQKSNGLEYA AKFIKKRRLS SSRRGVSREE IEREVDILRE IQHPNIITLH 60

DIFENKTDVV LILELVSGGE LFDFLAEKES LTEEEATQFL KQILDGVHYL HSKHIAHFDL 120

KPENIMLLDK NVPNPRIKLI DFGIAHKIEA GNEFKNIFGT PEFVAPEIVN YEPLGLEADM 180

WSIGVITYIL LSGASPFLGE TKQETLTNIS AVNYDFDEEY FSNTSELAKD FIRRLLVKDP 240

KKRMTIAQSL EHSWIKVIKR RNVRNEDSGK KPERRRLKTT RLKEYTIKSH SSMPPNNTYI 300

NFERFSKVLE EVAAAEEGLR ELEHSKKLFR EDIEALTSIY EEKEAWYKEE NESIGQDLRQ 360

LRQELHKTEA LKRQTQEEAK GALLAANGLK RGFGRLENRF EALAKQVASE MRFVQDLVRA 420

MEQEKLQESD CSIR 434

Nucleotide Sequence
(FASTA)

AGCGGTCAGT TTGCGATTGT GCGGAAGTGT CGGCAGAAGA GTAATGGGCT GGAGTACGCG 60

GCCAAGTTCA TCAAAAAGCG TCGCCTGTCG TCCAGCCGGC GGGGGGTGAG CCGGGAAGAG 120

ATCGAGCGGG AAGTGGACAT CCTGAGGGAG ATTCAACACC CCAACATCAT CACCCTGCAC 180

GACATCTTTG AGAACAAGAC GGACGTGGTG CTGATCCTGG AGCTGGTCTC TGGCGGGGAG 240

CTCTTTGACT TTCTGGCTGA GAAAGAGTCC CTGACTGAGG AGGAGGCCAC TCAGTTTCTG 300

AAGCAGATCC TGGATGGGGT CCACTACCTG CACTCCAAGC ACATTGCCCA CTTTGACCTA 360

AAGCCTGAGA ACATCATGCT TCTGGACAAG AATGTGCCCA ATCCTCGCAT CAAGCTGATC 420

GACTTTGGCA TTGCCCACAA AATTGAGGCC GGGAATGAGT TCAAGAACAT CTTTGGGACC 480

CCAGAGTTCG TGGCTCCTGA GATCGTGAAC TACGAGCCCC TGGGGCTAGA GGCTGACATG 540

TGGAGCATTG GAGTGATCAC CTACATCCTT TTAAGCGGCG CATCTCCATT CTTGGGTGAA 600

ACCAAACAAG AGACCCTGAC CAACATCTCG GCGGTGAACT ATGACTTTGA TGAGGAATAT 660

TTCAGTAACA CCAGCGAGCT GGCCAAGGAC TTCATCCGCC GACTACTCGT CAAGGACCCC 720

AAGAAGAGGA TGACCATTGC CCAGAGCCTG GAGCACTCCT GGATTAAGGT GATCAAGAGG 780

AGGAACGTGC GGAACGAGGA CAGCGGCAAG AAGCCCGAGC GGCGGCGGCT GAAGACCACC 840

CGGCTCAAGG AGTACACCAT CAAGTCCCAC TCCAGCATGC CCCCCAACAA CACCTACATC 900

AACTTCGAGC GCTTCTCCAA GGTGCTGGAG GAAGTGGCAG CGGCCGAGGA GGGCCTGAGG 960

GAGCTGGAGC ACAGTAAGAA GCTCTTCCGG GAGGACATCG AGGCCCTGAC CTCCATCTAC 1020

GAAGAGAAGG AGGCCTGGTA CAAGGAGGAG AACGAGAGCA TCGGCCAAGA CCTGCGGCAG 1080

CTCCGCCAGG AGCTCCACAA GACGGAGGCC CTGAAGCGGC AGACCCAGGA AGAGGCCAAG 1140

GGGGCCCTGC TCGCCGCCAA CGGGCTCAAG CGGGGCTTCG GGCGGCTGGA GAACCGCTTC 1200

GAGGCCCTGG CCAAGCAGGT GGCGTCTGAG ATGAGGTTCG TGCAGGACCT GGTGCGGGCC 1260

ATGGAGCAGG AGAAGCTGCA GGAGAGCGAC TGCAGCATCC GTTAG 1305

Domain Profile

S: 9     sGkfavvrkcrekstGkeyaakflkkrrlkssrrgvsreeierevavlkeirsepnvinl  68

         sG+fa+vrkcr+ks G eyaakf+kkrrl+ssrrgvsreeierev +l+ei+ +pn+i+l

Q: 1     SGQFAIVRKCRQKSNGLEYAAKFIKKRRLSSSRRGVSREEIEREVDILREIQ-HPNIITL  59

         69**************************************************.*******

S: 69    hevyenksdvililelvaGGelfdllaekeslseeeatellkqilegvkylhskkivhld  128

         h+++enk+dv+lilelv+GGelfd+laekesl+eeeat++lkqil+gv+ylhsk+i+h+d

Q: 60    HDIFENKTDVVLILELVSGGELFDFLAEKESLTEEEATQFLKQILDGVHYLHSKHIAHFD  119

         ************************************************************

S: 129   lkPenillldkkvpkgdiklidfGlsrkieegaelkeilGtPefvaPeivnyeplsletd  188

         lkPeni+lldk+vp+++iklidfG+++kie+g+e+k+i+GtPefvaPeivnyepl+le+d

Q: 120   LKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEIVNYEPLGLEAD  179

         ************************************************************

S: 189   mwsiGvityillsgasPflGdtkqetllnisavnldfseelfssvselakdfirrllvkd  248

         mwsiGvityillsgasPflG+tkqetl+nisavn+df+ee+fs++selakdfirrllvkd

Q: 180   MWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSNTSELAKDFIRRLLVKD  239

         ************************************************************

S: 249   pekrltieeclehswl  264

         p+kr+ti+++lehsw+

Q: 240   PKKRMTIAQSLEHSWI  255

         ***************8

Domain Sequence
(FASTA)

SGQFAIVRKC RQKSNGLEYA AKFIKKRRLS SSRRGVSREE IEREVDILRE IQHPNIITLH 60

DIFENKTDVV LILELVSGGE LFDFLAEKES LTEEEATQFL KQILDGVHYL HSKHIAHFDL 120

KPENIMLLDK NVPNPRIKLI DFGIAHKIEA GNEFKNIFGT PEFVAPEIVN YEPLGLEADM 180

WSIGVITYIL LSGASPFLGE TKQETLTNIS AVNYDFDEEY FSNTSELAKD FIRRLLVKDP 240

KKRMTIAQSL EHSWI 255

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006917	; P:induction of apoptosis
GO:0007243	; P:intracellular protein kinase cascade
GO:0090263	; P:positive regulation of canonical Wnt receptor signaling pathway

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR020675	; Myosin_light_ch_kinase-rel.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013