EKS-ORA-00081

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORA-00081

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/TSSK	407.5	3.0E-122	12	272	261

Status

Unreviewed

Ensembl Protein

ENSOANP00000008447

UniProt Accession

F7CS33;

Protein Name

Protein Synonyms/Alias

Gene Name

TSSK2

Gene Synonyms/Alias

TSSK2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOANG00000005303	ENSOANP00000008447	ENSOANT00000008449

Organism

Ornithorhynchus anatinus

Functional Description

Protein Length

347

Protein Sequence
(FASTA)

MDDAAILKKK GYVVGINLGK GSYAKVKSAY SERLKFNVAV KIIDRKKTPS DFVERFLPRE 60

MDILATVSHR CIIKTYEIFE TSDGRIYIVM ELGVQGDLLE FIKCRGALHE DVARKMFQQL 120

SSAIKYCHDL DVVHRDLKCE NLLLDKDFNV KLSDFGFSKR CHRDDSGKLL LSKTFCGSAA 180

YAAPEVLQGI PYQPKVYDIW SLGVILYIMV CGSMPYDDSD IKRMLRFQKE HRVDFPRSKH 240

LTSECKDLIY RMLQPDVHRR LRIDDILGHC WLQPAKARPP SSSSFKREAE AKPRAEPKPE 300

SRTGSRPDNR PTSKAPQRLL AVPETEEAGP AGGLEEPLGA EGGRASP 347

Nucleotide Sequence
(FASTA)

ATGGACGACG CCGCCATCCT CAAAAAGAAA GGCTACGTGG TGGGCATCAA CTTGGGGAAG 60

GGCTCCTACG CCAAAGTGAA ATCCGCCTAC TCCGAGCGCC TCAAGTTCAA CGTGGCGGTC 120

AAGATCATCG ACCGCAAGAA GACCCCCTCG GACTTCGTCG AAAGGTTCTT GCCCCGTGAG 180

ATGGACATCC TGGCCACCGT GAGCCACCGT TGCATCATCA AGACCTACGA GATCTTCGAG 240

ACTTCGGATG GCCGGATCTA CATCGTCATG GAACTGGGCG TGCAGGGCGA CCTGTTGGAG 300

TTCATCAAAT GCCGCGGGGC CCTGCACGAG GACGTGGCCC GCAAGATGTT CCAGCAGCTC 360

TCGTCGGCCA TCAAGTACTG CCACGACCTG GACGTGGTCC ACCGCGACCT CAAGTGCGAG 420

AACCTCCTCC TCGACAAGGA CTTCAACGTC AAGCTCTCCG ACTTCGGCTT CTCCAAGCGC 480

TGCCACCGCG ACGACTCCGG GAAGCTCTTG CTCAGCAAGA CCTTCTGCGG GTCGGCGGCC 540

TACGCGGCGC CCGAGGTGCT GCAGGGCATC CCCTACCAGC CCAAGGTGTA CGACATCTGG 600

AGCCTGGGCG TCATCCTGTA CATCATGGTC TGTGGCTCCA TGCCCTACGA CGACTCCGAC 660

ATCAAGCGCA TGCTGCGCTT CCAGAAGGAA CACCGGGTCG ACTTCCCGCG GTCCAAGCAC 720

CTGACCAGCG AGTGCAAGGA CCTCATCTAC CGCATGCTGC AGCCCGACGT GCACCGGCGG 780

CTGCGCATCG ACGACATCCT CGGCCACTGC TGGCTGCAGC CCGCCAAGGC CAGGCCCCCC 840

TCGTCCAGCT CCTTCAAGCG GGAGGCGGAG GCCAAGCCCC GGGCCGAGCC CAAGCCGGAG 900

AGTCGCACGG GGTCACGGCC GGACAACCGG CCGACCTCCA AGGCCCCGCA GCGGCTCCTA 960

GCTGTCCCGG AGACGGAGGA GGCGGGCCCG GCAGGCGGGT TGGAAGAGCC CTTGGGAGCA 1020

GAAGGGGGCC GGGCCAGCCC CTAG 1044

Domain Profile

S: 1     lklgkkiGeGsyskvkeaysekkklkvavkiidkkkapedyvkkFlPReleilktlkhkn  60

         + +g ++G+Gsy+kvk+ayse+ k++vavkiid+kk+p+d+v++FlPRe++il+t++h+

Q: 12    YVVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPSDFVERFLPREMDILATVSHRC  71

         56899*******************************************************

S: 61    ivklyeiietsd.kiylvlelaaqgdllelikesgaleeeearklfsqlvsavkylhsld  119

         i+k+yei+etsd +iy+v+el+ qgdlle+ik++gal+e+ ark+f+ql+sa+ky+h+ld

Q: 72    IIKTYEIFETSDgRIYIVMELGVQGDLLEFIKCRGALHEDVARKMFQQLSSAIKYCHDLD  131

         ************************************************************

S: 120   ivhRDlkcenilldkkenvklsDFgFakkvkr...skselsktfCGsaaYaaPevlrgik  176

         +vhRDlkcen+lldk++nvklsDFgF+k+++r   +k  lsktfCGsaaYaaPevl+gi+

Q: 132   VVHRDLKCENLLLDKDFNVKLSDFGFSKRCHRddsGKLLLSKTFCGSAAYAAPEVLQGIP  191

         *******************************99989999*********************

S: 177   ydpklsDvWslGvilyvmvvgklPfddsdikkllrsqkkrkvkfpksltlseeckdlile  236

         y+pk++D+WslGvily+mv+g++P+ddsdik++lr qk+++v fp+s++l++eckdli++

Q: 192   YQPKVYDIWSLGVILYIMVCGSMPYDDSDIKRMLRFQKEHRVDFPRSKHLTSECKDLIYR  251

         ************************************************************

S: 237   llqldakkRltikevlessWl  257

         +lq+d+++Rl i+++l ++Wl

Q: 252   MLQPDVHRRLRIDDILGHCWL  272

         ********************7

Domain Sequence
(FASTA)

YVVGINLGKG SYAKVKSAYS ERLKFNVAVK IIDRKKTPSD FVERFLPREM DILATVSHRC 60

IIKTYEIFET SDGRIYIVME LGVQGDLLEF IKCRGALHED VARKMFQQLS SAIKYCHDLD 120

VVHRDLKCEN LLLDKDFNVK LSDFGFSKRC HRDDSGKLLL SKTFCGSAAY AAPEVLQGIP 180

YQPKVYDIWS LGVILYIMVC GSMPYDDSDI KRMLRFQKEH RVDFPRSKHL TSECKDLIYR 240

MLQPDVHRRL RIDDILGHCW L 261

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Dasypus novemcinctus"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tarsius syrichta"; ?>Tupaia belangeri"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0001669	; C:acrosomal vesicle
GO:0005814	; C:centriole
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0046777	; P:protein autophosphorylation

KEGG

oaa:100089605

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013