EKS-ORA-00375

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORA-00375

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/WEE	219.7	5.0E-65	110	295	186

Status

Unreviewed

Ensembl Protein

ENSOANP00000010004

UniProt Accession

F6WJP1;

Protein Name

Protein Synonyms/Alias

Gene Name

PKMYT1

Gene Synonyms/Alias

PKMYT1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOANG00000006251	ENSOANP00000010004	ENSOANT00000010006

Organism

Ornithorhynchus anatinus

Functional Description

Protein Length

482

Protein Sequence
(FASTA)

ILERSPELDM PVPSEGVTPP LNTTPIPVPV YFRHADPGFS LKQPGSLSRS LPPRPPTKGS 60

APVSRLFPSR TPCWSQPRPR GVSFRGGASE ALEGRDYDPS RPESFFQQSF QRLGRLGRGS 120

FGEVFKVRSK EDGRLYAVKR SVSPFRGPQD RVRKLAEVGG HEKVGRHPRC VHLERAWEEG 180

GLLYLQTELC GPSLQQHCET RGTGLPEAQV WGYLRDTLLA LAHLHGRGLV HLDVKPANIF 240

LGPRGRCKLG DFGLLVELGA AGASEAQEGD PRYMAPELLQ GCYGTAADVF RCGLSPPEGR 300

FRGDHCPLTG LSHELRSVLT MMLEPEPERR ATAETLLAFG TIRKLGHWGC LGMVASEALS 360

QGRALCQGLL SLLCWLWHYL AHPTNWLRPP CPPTTPPGSP LPSLLDSSIS SDWDEDCVGP 420

PLSPVTILAR SPGGTSTPRH GSPDVKEQLD LSGISPDLPP GPIPSFEPRN LLSLFEDSLD 480

PN 482

Nucleotide Sequence
(FASTA)

ATTCTAGAGA GATCTCCTGA GTTGGACATG CCAGTCCCGT CGGAGGGGGT CACCCCACCC 60

CTGAATACCA CTCCAATTCC CGTCCCAGTG TATTTTCGCC ACGCGGATCC CGGCTTCTCT 120

CTCAAGCAGC CTGGGAGCCT GAGCCGCAGC CTCCCGCCTC GGCCCCCCAC CAAAGGAAGC 180

GCCCCTGTCA GTCGCCTCTT CCCTTCACGC ACGCCATGCT GGAGTCAGCC CCGGCCCCGA 240

GGAGTGTCAT TCCGTGGGGG GGCCTCGGAG GCACTGGAAG GCCGTGACTA CGATCCCAGT 300

CGGCCCGAAT CCTTCTTCCA GCAAAGCTTT CAGCGGCTCG GGCGCCTGGG GCGTGGTTCC 360

TTTGGGGAGG TCTTCAAGGT CCGCTCAAAG GAAGATGGTC GGCTGTATGC AGTGAAGCGC 420

TCAGTGTCCC CGTTCCGGGG TCCCCAGGAT CGGGTCCGCA AGCTGGCCGA AGTCGGGGGC 480

CACGAGAAAG TGGGACGGCA CCCCCGCTGC GTGCACCTGG AGAGAGCCTG GGAAGAGGGG 540

GGGCTCCTGT ACCTGCAGAC GGAGCTGTGC GGGCCCAGTC TGCAGCAACA CTGTGAGACT 600

CGGGGAACGG GCCTGCCCGA AGCCCAGGTT TGGGGCTACC TGCGGGACAC GCTGCTGGCC 660

TTGGCACACC TGCACGGCCG AGGGCTGGTC CACCTGGACG TCAAGCCGGC CAACATATTC 720

CTGGGACCCA GGGGCCGCTG CAAGCTGGGA GACTTTGGGC TTCTGGTGGA GCTGGGGGCG 780

GCTGGGGCCA GCGAGGCCCA GGAGGGCGAC CCCCGCTACA TGGCCCCCGA GCTGCTGCAG 840

GGCTGCTACG GGACCGCGGC CGATGTGTTC AGATGTGGCT TGAGCCCTCC TGAGGGACGG 900

TTTCGGGGTG ACCACTGTCC GCTCACAGGC TTGTCCCACG AGCTGCGCTC CGTCCTCACC 960

ATGATGCTGG AACCGGAACC AGAACGACGG GCCACAGCCG AGACCCTACT GGCCTTCGGA 1020

ACCATCAGGA AGCTGGGGCA CTGGGGGTGC CTGGGGATGG TGGCCAGTGA AGCCTTGAGT 1080

CAAGGTCGGG CACTGTGCCA GGGCCTGCTG TCCCTCCTGT GCTGGCTATG GCACTATCTG 1140

GCCCACCCAA CCAACTGGCT CCGTCCTCCG TGTCCCCCGA CGACGCCCCC CGGCTCCCCA 1200

CTTCCTAGCC TCCTGGACAG CAGCATCTCC AGTGACTGGG ATGAAGACTG TGTGGGCCCC 1260

CCGCTGTCTC CAGTGACGAT TCTGGCCCGA TCCCCGGGGG GAACCTCTAC GCCCCGGCAC 1320

GGCTCCCCAG ACGTCAAGGA ACAGCTGGAC CTAAGTGGAA TCAGCCCAGA CCTGCCCCCA 1380

GGCCCCATCC CCTCCTTTGA GCCCCGCAAT CTCCTCAGCC TCTTCGAGGA TTCGCTTGAC 1440

CCCAACTGA 1449

Domain Profile

S: 1     FeevekiGkGefgevfkvvkredgklyAikkskkplkglskekkalrEvtahavlgqhen  60

         F+++ ++G+G+fgevfkv+++edg+lyA+k+s +p++g +++ ++l+Ev +h+++g+h+

Q: 110   FQRLGRLGRGSFGEVFKVRSKEDGRLYAVKRSVSPFRGPQDRVRKLAEVGGHEKVGRHPR  169

         89999*******************************************************

S: 61    vvryisaWeeddslyiqtElCeggsLeaalqeceakkkaleeaelkkilldlllglrylH  120

         +v++ +aWee + ly+qtElC g sL+++   ce+  + l+ea+++ +l d ll+l +lH

Q: 170   CVHLERAWEEGGLLYLQTELC-GPSLQQH---CETRGTGLPEAQVWGYLRDTLLALAHLH  225

         *********************.*******...999999**********************

S: 121   ssslvHlDikpenifitkevtlklgDlGlvtelnsedkskveEGDsrylakEilqeeysk  180

          + lvHlD+kp+nif+  ++++klgD+Gl++el+++ +s+++EGD ry+a+E+lq++y +

Q: 226   GRGLVHLDVKPANIFLGPRGRCKLGDFGLLVELGAAGASEAQEGDPRYMAPELLQGCYGT  285

         ************************************************************

S: 181   lkaDiFslglt  191

         + aD+F  gl+

Q: 286   A-ADVFRCGLS  295

         *.****99985

Domain Sequence
(FASTA)

FQRLGRLGRG SFGEVFKVRS KEDGRLYAVK RSVSPFRGPQ DRVRKLAEVG GHEKVGRHPR 60

CVHLERAWEE GGLLYLQTEL CGPSLQQHCE TRGTGLPEAQ VWGYLRDTLL ALAHLHGRGL 120

VHLDVKPANI FLGPRGRCKL GDFGLLVELG AAGASEAQEG DPRYMAPELL QGCYGTAADV 180

FRCGLS 186

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0010923	; P:negative regulation of phosphatase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013