EKS-ORA-00175

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORA-00175

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/RCK	507.2	1.3E-152	4	284	281

Status

Unreviewed

Ensembl Protein

ENSOANP00000011444

UniProt Accession

F6X0F4;

Protein Name

Protein Synonyms/Alias

Gene Name

MAK

Gene Synonyms/Alias

MAK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOANG00000007190	ENSOANP00000011444	ENSOANT00000011446

Organism

Ornithorhynchus anatinus

Functional Description

Protein Length

623

Protein Sequence
(FASTA)

MNRYTTMMQL GDGTYGSVLM GKSNESGELV AIKRMKRKFY SWDECMNLRE VKSLKKLNHA 60

NVIKLKEVIR ENDHLYFVFE YMKENLYQLM KDRNKLFPES VIRNIMYQIL QGLAFIHKHG 120

FFHRDMKPEN LLCMGPELVK IADFGLAREL RSQPPYTDYV STRWYRAPEV LLRSSVYSSP 180

IDVWAVGSIM AELYTLRPLF PGTSEVDEIF KICQVLGTPK KSDWPEGYQL ASSMNFRFPQ 240

CVPINLKTLI PNASSDGLQL MSDMLHWNPK KRPTASQALK YPFFQVGQIV GSPPQYMEKK 300

QSLHKQFQLT EPKPPLSEFE IQHPLNALDK NQLQAQSRLN HQPLQPIQLL KNMIVQQIPK 360

QQPQQKQQQL FPSISKNPSP KQNGAVGYKN GRRRWGQNLF KTDDSWEDFD NSDLGAVHSK 420

KPSMSVLKEK KAKDSSFSDP DPAPASCNQA RGENKSLPAG AFLKNDTDLS TASTAKQYYL 480

RQSRYLPGVN PKNVSLLAPG KEGNPYVWNN QMFPKPLASI GAGLSFNKNN TGSLEGYASY 540

NQHGGYVPSF HKKEVGSAGQ RLHLAPTGAT NSDYAWKTQT GRAQFPGPAY SSTAKDINIL 600

NRPHPIHSVH GRTDWVAKYG GHR 623

Nucleotide Sequence
(FASTA)

ATGAACCGCT ATACAACTAT GATGCAACTG GGAGATGGCA CCTACGGGAG TGTACTTATG 60

GGGAAGAGCA ATGAATCTGG AGAGTTGGTG GCTATCAAAA GGATGAAAAG GAAATTCTAT 120

TCTTGGGATG AGTGTATGAA TTTGAGAGAA GTTAAGTCTC TGAAGAAACT TAATCATGCC 180

AATGTGATTA AACTGAAAGA AGTTATCAGA GAAAATGACC ATCTTTATTT TGTGTTTGAA 240

TATATGAAGG AGAATCTCTA TCAGTTAATG AAGGACAGAA ACAAGTTGTT CCCTGAGTCA 300

GTCATCAGAA ACATCATGTA TCAAATACTG CAGGGGTTAG CTTTCATCCA TAAACACGGT 360

TTCTTCCATC GCGATATGAA GCCTGAAAAT CTGCTTTGTA TGGGTCCAGA ACTTGTAAAA 420

ATTGCTGATT TTGGGCTAGC GAGAGAATTA CGGTCCCAGC CACCATATAC GGATTACGTA 480

TCTACCAGAT GGTACCGCGC CCCTGAAGTT TTGTTGAGAT CGTCGGTTTA TAGCTCTCCC 540

ATTGATGTGT GGGCTGTAGG AAGCATCATG GCTGAGCTAT ACACGTTAAG ACCACTTTTC 600

CCAGGGACAA GTGAGGTCGA TGAAATCTTC AAAATTTGCC AAGTGTTAGG GACTCCCAAG 660

AAGAGTGATT GGCCAGAGGG ATATCAGCTT GCTTCCTCCA TGAATTTCCG CTTTCCACAG 720

TGTGTTCCCA TCAACTTGAA AACTCTTATT CCCAATGCCA GTAGTGACGG ATTACAGCTT 780

ATGAGCGACA TGCTGCATTG GAATCCAAAG AAACGACCGA CAGCAAGCCA GGCTTTGAAG 840

TACCCCTTTT TTCAAGTTGG TCAAATAGTA GGATCTCCTC CACAATATAT GGAAAAGAAG 900

CAATCTCTTC ATAAACAATT TCAGCTTACA GAGCCTAAAC CGCCATTGTC TGAGTTTGAA 960

ATTCAGCACC CCCTAAATGC ACTGGACAAG AATCAACTAC AGGCCCAATC AAGACTTAAC 1020

CATCAACCAC TACAGCCAAT TCAGCTGCTA AAGAACATGA TCGTCCAGCA GATTCCAAAA 1080

CAACAGCCTC AGCAAAAGCA ACAACAATTA TTTCCAAGTA TCAGCAAAAA CCCATCTCCT 1140

AAGCAAAATG GTGCTGTTGG CTATAAAAAT GGTAGGCGGC GTTGGGGTCA AAATTTGTTT 1200

AAAACAGATG ATAGCTGGGA AGATTTTGAC AACTCTGACC TTGGAGCTGT ACATTCCAAG 1260

AAGCCCAGCA TGTCTGTTTT AAAAGAAAAG AAAGCAAAAG ATTCTTCATT TAGTGATCCA 1320

GACCCAGCTC CCGCAAGCTG CAACCAGGCC AGAGGGGAAA ACAAGAGTTT GCCAGCTGGG 1380

GCTTTTTTAA AAAATGACAC TGACTTATCA ACTGCTTCGA CCGCCAAACA ATATTACCTG 1440

AGACAATCAA GATACCTTCC AGGTGTAAAT CCCAAGAATG TGTCTTTACT AGCCCCTGGT 1500

AAAGAAGGAA ACCCATATGT TTGGAATAAT CAAATGTTTC CCAAGCCTCT GGCATCAATT 1560

GGAGCGGGAC TGTCTTTCAA CAAAAATAAT ACAGGAAGCC TTGAAGGCTA CGCTAGTTAT 1620

AACCAGCATG GAGGATATGT CCCTTCATTT CACAAAAAGG AAGTTGGTTC AGCTGGACAA 1680

AGGCTACATT TAGCACCTAC TGGTGCCACC AATTCAGATT ATGCCTGGAA AACACAAACA 1740

GGTCGGGCCC AATTTCCAGG TCCCGCTTAC AGTTCAACAG CAAAAGATAT AAATATTTTA 1800

AACCGCCCCC ATCCAATTCA TTCAGTGCAT GGAAGAACAG ACTGGGTGGC CAAGTATGGA 1860

GGCCATCGAT AG 1872

Domain Profile

S: 1     yklikklGdGtfgevllakslktgelvaikkmkrkfesleevtnlrevkslkklnahdni  60

         y+++ +lGdGt+g+vl++ks+++gelvaik+mkrkf+s++e++nlrevkslkkln h+n+

Q: 4     YTTMMQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLN-HANV  62

         99*****************************************************.****

S: 61    iklkeviidrendslylvlelmeenlyqlikdrrkllsesklksilyqilkglafihkhg  120

         iklkevi  rend+ly+v+e+m+enlyql+kdr+kl++es++++i+yqil+glafihkhg

Q: 63    IKLKEVI--RENDHLYFVFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG  120

         *******..***************************************************

S: 121   ffhrdlkPenilikgselvkladfGlarevrsknPytdyvstrwyraPevllrsgvyssp  180

         ffhrd+kPen+l++g+elvk+adfGlare+rs++PytdyvstrwyraPevllrs+vyssp

Q: 121   FFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSP  180

         ************************************************************

S: 181   ldlwavGcvlaevavlrplfPGaseidqifkilevlGtPkkkewdeayklasalnlkfpq  240

         +d+wavG+++ae+++lrplfPG+se+d+ifki++vlGtPkk++w+e+y+las++n++fpq

Q: 181   IDVWAVGSIMAELYTLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQ  240

         ************************************************************

S: 241   vegsslktlvsnaskealellkdllaydPderataqqalkypyf  284

         +++++lktl++nas+++l+l++d+l+++P++r+ta+qalkyp+f

Q: 241   CVPINLKTLIPNASSDGLQLMSDMLHWNPKKRPTASQALKYPFF  284

         *******************************************9

Domain Sequence
(FASTA)

YTTMMQLGDG TYGSVLMGKS NESGELVAIK RMKRKFYSWD ECMNLREVKS LKKLNHANVI 60

KLKEVIREND HLYFVFEYMK ENLYQLMKDR NKLFPESVIR NIMYQILQGL AFIHKHGFFH 120

RDMKPENLLC MGPELVKIAD FGLARELRSQ PPYTDYVSTR WYRAPEVLLR SSVYSSPIDV 180

WAVGSIMAEL YTLRPLFPGT SEVDEIFKIC QVLGTPKKSD WPEGYQLASS MNFRFPQCVP 240

INLKTLIPNA SSDGLQLMSD MLHWNPKKRP TASQALKYPF F 281

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005813	; C:centrosome
GO:0030496	; C:midbody
GO:0072686	; C:mitotic spindle
GO:0005634	; C:nucleus
GO:0001917	; C:photoreceptor inner segment
GO:0001750	; C:photoreceptor outer segment
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0003713	; F:transcription coactivator activity
GO:0046777	; P:protein autophosphorylation

KEGG

oaa:100082794

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013