EKS-ORA-00425

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORA-00425

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/RSKL	301.4	1.3E-89	874	1064	191

Status

Unreviewed

Ensembl Protein

ENSOANP00000013545

UniProt Accession

F6WP48;

Protein Name

Protein Synonyms/Alias

Gene Name

RPS6KC1

Gene Synonyms/Alias

RPS6KC1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOANG00000008515	ENSOANP00000013545	ENSOANT00000013548

Organism

Ornithorhynchus anatinus

Functional Description

Protein Length

1074

Protein Sequence
(FASTA)

MTSPREPGGE LARFYTVTEP QRHPRGHTVY KVTARIVSRR NPEDVQEIVV WKRYSDFKKL 60

HKDLWQIHRN LFRHSELFPP FAKGIVFGRF DETVIEERRQ CAEDLLQFSA NIPALYNSKQ 120

LEDFFKGGEV HDGSELIGPA EPFTDSLIDS FSDCSSEGLS SDSDLISLTV DADSLAEIDD 180

GMASNQNSPS RTSGLNFSPE RVAQGAVSSD YERGRTEGER ESRSLFPGNL RPKFGKQDYL 240

EKAGELIKLA LKKEEEDDYE AAFSFYRKGV DLLLEGVQGE SSPTRREAVK KRTAEYLMRA 300

ERLSSLCRKP QPDDGTIPRP PGSLSSRPSW NLRSPAEELK AFRVLGVIDK VLLIMDKRTQ 360

QTFILKGLRK SSEYSRNRKT IIPRCVPNMV CLHEYIITEE SVFLVLQHAE GGKLWSYIGK 420

FLNRSPEESF DHPHVKRSSP TKMHLQEPAP NPDSSSFDSR GSDCGSMLKV LPLKTSLTPS 480

SQDDSSNQEE DGQDISSKWP DSDSSSEEEC TTSYLTLCNE YGQDKIDPGT LNEESLLKME 540

GNRVSAKYER DLPGHVAVDC ESFSSQLTSQ ELKFLTDDAN SEVVSPTRIS DSLSKSKNSP 600

MELFRIDSKD STSEVLGIDF GEKLYNLKAE PLKPFLPFLD PDGSPRSLAA RESKMVSNAQ 660

DTISRGSNDS VPVISFKDAA FDDMNSTDEG RPDLLVNLPG MLEQAKDVAT VGLAMFTQTN 720

IGILESNLLE APDVLRLNLS ADQSLAHEEK GLQELLDPFS QTSLRKAGKN YEEDGMGTLF 780

TGAVDQPVSS GASLLDGSIP ETRGLGLVAP LVEGTNSEES LLFISNSLPG ANKPSANAEE 840

SSKTEEVMLF VDQAEDSGKE EPSPPVSRLD GIETAAKRES ESAVEGDKEI HQIFEDLDKR 900

LALTSRLYIP EDCIQRWAAE MVIALDALHR EGIVCRDLNP NNILLNDRGH IQLTYFSRWS 960

EVEDSCDSDA MERMYCAPEV GAITEETEAC DWWSLGAVLF ELLTGKTLIE CHPAGINTHT 1020

SLNMPECISE EARSLTQQLL QFNPIERLGA GVAGVEDIKS HPFFTPVNWA ELMR 1074

Nucleotide Sequence
(FASTA)

ATGACCTCCC CCCGGGAGCC GGGCGGGGAG CTGGCCCGTT TCTACACCGT CACCGAGCCG 60

CAGCGCCACC CGAGGGGCCA CACCGTCTAT AAAGTCACCG CCCGGATTGT TTCAAGAAGA 120

AATCCAGAGG ATGTGCAGGA GATAGTTGTG TGGAAACGGT ACAGTGACTT TAAGAAACTG 180

CATAAAGACC TTTGGCAAAT TCACAGAAAT CTGTTTAGAC ATAGTGAATT ATTTCCACCT 240

TTTGCCAAAG GAATCGTATT TGGTCGGTTT GATGAAACAG TGATTGAAGA AAGAAGACAG 300

TGCGCTGAAG ATCTTCTGCA ATTCTCTGCC AACATCCCCG CTCTTTATAA CAGTAAACAG 360

CTTGAAGACT TTTTCAAGGG TGGAGAGGTT CATGATGGCT CTGAATTGAT TGGTCCTGCT 420

GAACCTTTTA CAGATTCCTT GATTGACAGC TTCTCTGATT GCAGTTCTGA AGGTCTCTCC 480

AGTGACAGTG ATCTTATCTC TTTGACCGTC GATGCGGACT CTTTGGCTGA GATAGATGAT 540

GGAATGGCAT CCAATCAAAA TTCTCCCAGC AGAACTTCTG GGCTCAATTT TTCTCCAGAA 600

CGTGTAGCAC AAGGAGCCGT TTCTTCTGAC TATGAACGGG GCAGGACAGA AGGAGAGCGG 660

GAAAGCCGGA GTCTGTTTCC CGGCAATTTA AGGCCCAAGT TTGGCAAACA AGATTATTTA 720

GAGAAAGCAG GAGAACTAAT AAAGCTGGCC TTGAAGAAAG AGGAGGAAGA TGACTATGAA 780

GCTGCCTTTA GTTTTTACAG GAAGGGAGTT GATCTACTCC TGGAAGGTGT CCAAGGTGAG 840

TCAAGTCCAA CACGTCGAGA AGCAGTGAAG AAAAGAACAG CGGAATACCT TATGCGAGCC 900

GAGAGACTCT CCAGTCTCTG TCGAAAACCT CAACCGGATG ATGGAACCAT ACCTAGGCCT 960

CCAGGATCAC TAAGTTCAAG GCCCTCTTGG AACCTAAGGA GCCCTGCCGA GGAACTGAAG 1020

GCCTTCAGAG TCCTTGGGGT GATTGACAAG GTTTTGCTAA TAATGGACAA GAGGACACAG 1080

CAGACATTCA TACTGAAAGG TCTAAGGAAA AGTAGTGAGT ACAGCAGGAA CAGAAAGACC 1140

ATCATCCCCC GCTGTGTGCC CAACATGGTG TGTCTGCACG AGTACATCAT CACCGAGGAG 1200

TCTGTATTTC TTGTCCTGCA ACATGCAGAA GGTGGCAAAT TATGGTCTTA CATCGGTAAA 1260

TTCTTAAACA GAAGTCCTGA AGAAAGTTTT GACCACCCCC ATGTAAAAAG ATCCAGTCCT 1320

ACTAAAATGC ACCTGCAAGA GCCAGCTCCT AACCCCGACA GCAGCAGCTT TGATTCCAGA 1380

GGAAGCGATT GCGGGAGCAT GCTCAAAGTT TTACCTTTGA AGACCAGTCT TACCCCAAGC 1440

TCCCAAGATG ACAGCAGTAA CCAGGAAGAA GATGGCCAAG ATATCTCTTC GAAATGGCCT 1500

GACTCTGACT CGAGTTCGGA AGAAGAATGC ACTACCAGTT ACTTAACATT ATGCAATGAA 1560

TACGGGCAGG ATAAAATTGA TCCTGGCACC CTGAACGAGG AGTCTTTATT GAAGATGGAG 1620

GGAAACCGTG TTAGTGCTAA ATATGAAAGA GACTTACCAG GTCACGTTGC TGTTGACTGT 1680

GAGAGTTTCA GTTCTCAGCT AACAAGTCAG GAACTGAAAT TCCTTACTGA TGATGCCAAC 1740

TCTGAAGTAG TTAGTCCTAC CAGGATTTCG GATTCTTTAA GCAAATCCAA GAATAGTCCT 1800

ATGGAGCTCT TCAGGATAGA CAGCAAGGAC AGTACCAGTG AGGTCCTGGG GATAGATTTT 1860

GGAGAAAAAT TGTATAACTT AAAGGCAGAA CCCTTGAAAC CATTCCTTCC CTTTCTTGAT 1920

CCAGATGGTA GTCCCAGGAG TCTTGCGGCT AGAGAAAGTA AAATGGTTTC CAACGCTCAA 1980

GACACCATAA GTAGAGGGTC GAACGACTCA GTCCCCGTGA TTTCGTTTAA AGATGCTGCT 2040

TTCGACGACA TGAATAGCAC CGACGAAGGG AGGCCCGATC TCCTGGTTAA TCTGCCTGGG 2100

ATGTTGGAGC AAGCAAAAGA CGTTGCAACA GTGGGGCTAG CCATGTTTAC ACAGACCAAT 2160

ATAGGCATCT TAGAGAGTAA TCTCTTAGAG GCCCCTGATG TTTTACGGTT GAATCTTAGT 2220

GCTGACCAGA GCCTTGCCCA CGAAGAGAAG GGCCTGCAGG AATTGTTAGA TCCATTTAGC 2280

CAGACATCCC TCAGGAAGGC AGGGAAGAAC TATGAAGAGG ATGGTATGGG AACGTTGTTT 2340

ACAGGTGCTG TTGACCAGCC TGTCTCGTCA GGTGCGTCGT TGTTGGATGG TTCAATCCCT 2400

GAGACTCGAG GACTTGGGCT AGTAGCTCCT TTAGTAGAGG GAACTAACTC AGAAGAAAGC 2460

TTATTATTTA TTTCTAACTC ACTCCCAGGG GCTAATAAAC CCAGTGCAAA TGCAGAAGAG 2520

AGTTCAAAAA CGGAAGAAGT AATGCTGTTT GTGGATCAGG CCGAAGACTC TGGGAAAGAG 2580

GAGCCATCTC CGCCTGTTTC CCGGCTGGAT GGAATCGAGA CTGCAGCCAA GAGGGAAAGT 2640

GAATCAGCAG TAGAAGGAGA CAAGGAAATT CATCAGATTT TTGAGGACCT CGATAAAAGA 2700

TTAGCACTAA CCTCCAGGTT ATATATCCCA GAGGACTGCA TTCAGAGATG GGCAGCTGAA 2760

ATGGTTATAG CCCTCGATGC TTTACACAGA GAAGGAATTG TGTGCCGCGA TTTGAACCCA 2820

AACAACATCT TATTGAATGA TAGAGGACAC ATTCAGCTAA CGTATTTTAG CAGGTGGAGT 2880

GAGGTTGAAG ATTCCTGTGA CAGCGATGCC ATGGAGAGAA TGTACTGTGC CCCAGAGGTT 2940

GGAGCAATCA CAGAGGAAAC GGAAGCCTGT GATTGGTGGA GTTTGGGTGC TGTCCTCTTT 3000

GAACTTCTAA CTGGCAAGAC TCTGATTGAG TGCCATCCAG CGGGAATAAA CACTCACACA 3060

TCTTTGAATA TGCCGGAATG TATCTCTGAA GAGGCCCGAT CACTTACTCA ACAGCTTTTG 3120

CAGTTCAACC CTATAGAACG CCTTGGAGCT GGAGTGGCCG GTGTGGAAGA CATCAAATCT 3180

CATCCATTTT TCACCCCTGT GAATTGGGCA GAATTAATGA GATGA 3225

Domain Profile

S: 174   rirregqnsspssskeiklvsedadkslealsrgldkalqsvdkalslrravwslpEeli  233

          + + + +s     kei++++ed+dk+l+++sr                    ++pE++i

Q: 874   TAAKRESESAVEGDKEIHQIFEDLDKRLALTSR-------------------LYIPEDCI  914

         222333334444567777777777777777777...................78******

S: 234   kqWaaelvvaleaLHeegvlirDlnadniLldskGhllltYfgrwsevekscrreavdnl  293

         ++Waae+v+al+aLH+eg+++rDln++niLl+++Gh++ltYf+rwseve+sc+++a++++

Q: 915   QRWAAEMVIALDALHREGIVCRDLNPNNILLNDRGHIQLTYFSRWSEVEDSCDSDAMERM  974

         ************************************************************

S: 294   ysAPEvgaiselteasDwWslGalLyelLtGkalaeahPsgiqahtelqlPevvSeeAkd  353

         y+APEvgai+e+tea+DwWslGa+L+elLtGk+l e+hP+gi++ht l++Pe++SeeA++

Q: 975   YCAPEVGAITEETEACDWWSLGAVLFELLTGKTLIECHPAGINTHTSLNMPECISEEARS  1034

         ************************************************************

S: 354   LleeLLqfePalRlGaGeagvdelkaHPFF  383

         L ++LLqf+P +RlGaG+agv+++k+HPFF

Q: 1035  LTQQLLQFNPIERLGAGVAGVEDIKSHPFF  1064

         *****************************9

Domain Sequence
(FASTA)

TAAKRESESA VEGDKEIHQI FEDLDKRLAL TSRLYIPEDC IQRWAAEMVI ALDALHREGI 60

VCRDLNPNNI LLNDRGHIQL TYFSRWSEVE DSCDSDAMER MYCAPEVGAI TEETEACDWW 120

SLGAVLFELL TGKTLIECHP AGINTHTSLN MPECISEEAR SLTQQLLQFN PIERLGAGVA 180

GVEDIKSHPF F 191

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005769	; C:early endosome
GO:0005524	; F:ATP binding
GO:0035091	; F:phosphatidylinositol binding
GO:0004672	; F:protein kinase activity
GO:0007154	; P:cell communication

KEGG

oaa:100076026

;

InterPros

IPR011009	; Kinase-like_dom.
IPR007330	; MIT.
IPR001683	; Phox.
IPR000719	; Prot_kinase_cat_dom.

Pfam

PF04212	; MIT; 1.
PF00069	; Pkinase; 1.
PF00787	; PX; 1.

SMARTs

SM00745	; MIT; 1.
SM00312	; PX; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS50195	; PX; 1.

Prints

Created Date

20-Feb-2013