EKS-ORA-00194

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORA-00194

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/NKF1	406.1	6.8E-122	43	302	260

Status

Unreviewed

Ensembl Protein

ENSOANP00000013803

UniProt Accession

F6R7G9;

Protein Name

Serine/threonine-protein kinase SBK1

Protein Synonyms/Alias

SH3-binding kinase 1;

Gene Name

SBK1

Gene Synonyms/Alias

SBK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOANG00000008664	ENSOANP00000013803	ENSOANT00000013806

Organism

Ornithorhynchus anatinus

Functional Description

Protein Length

396

Protein Sequence
(FASTA)

MSAGSIEQEP TRKLACCGVP LITEDMQSLT IRTLASTDIH KHYDLIRELG KGTYGKVDLV 60

SHKSTGTKMA LKFVNKSKTK LKNFLREFSI TNTLSSSPFI IKVFDVVFET EDCYVFAQEY 120

APGGDLFDII PPQVGLPEDM VKRCVQQLGL ALDYMHSKHL VHRDIKPENV LLFDRDCRRV 180

KLADFGMTRK AGCRVKRVSG TIPYTAPEVC RAGRAEGLAV DTSIDVWAFG VLIFCVLTGN 240

FPWEAASATD AFFEEFVRWQ RGRLAGLPSQ WRRFTDHALR MFQRLLALDP EKRCPVKEAF 300

HFIKYELVTE ARRRPSCRGR RPAGDKLSAG PLRHETPTSC TPAPLKRTVL TESGGGPCLS 360

SADSSLPSPG PPGRTDGRQD KGKGQMVLAT AIEICV 396

Nucleotide Sequence
(FASTA)

ATGAGTGCCG GCTCCATCGA GCAGGAGCCC ACACGCAAGC TGGCATGTTG CGGCGTGCCC 60

CTCATCACCG AGGACATGCA GTCCCTCACC ATCCGAACCC TCGCCAGCAC CGACATCCAC 120

AAACACTACG ACCTGATCCG GGAGCTCGGC AAGGGCACTT ACGGAAAGGT GGATCTCGTC 180

TCCCACAAGA GCACAGGTAC CAAGATGGCA CTGAAGTTTG TCAACAAGAG CAAGACCAAG 240

CTGAAGAACT TCCTGCGGGA ATTCAGCATC ACCAACACCC TTTCCTCCAG CCCCTTCATC 300

ATCAAGGTCT TCGATGTCGT CTTTGAGACG GAGGACTGCT ACGTCTTTGC ACAGGAGTAC 360

GCGCCCGGGG GTGACCTCTT TGACATCATC CCACCTCAGG TGGGGCTGCC CGAGGACATG 420

GTGAAGCGCT GCGTGCAGCA ACTGGGCCTG GCCCTGGACT ACATGCACAG CAAGCACCTG 480

GTGCACCGGG ACATCAAGCC GGAGAACGTG CTGCTCTTCG ACCGCGACTG CCGCCGGGTC 540

AAGCTGGCCG ACTTCGGCAT GACCCGCAAG GCGGGCTGCC GGGTCAAGCG GGTCAGCGGC 600

ACCATCCCGT ACACGGCGCC CGAGGTGTGC CGGGCGGGGC GGGCCGAGGG CCTGGCCGTG 660

GACACCAGCA TCGACGTGTG GGCCTTCGGC GTCCTCATCT TCTGCGTGCT GACGGGCAAC 720

TTCCCCTGGG AGGCCGCTTC GGCCACGGAC GCCTTCTTCG AGGAGTTCGT GCGGTGGCAG 780

AGGGGGCGCC TGGCGGGGCT GCCCTCCCAG TGGCGCCGCT TCACGGACCA CGCCCTGCGC 840

ATGTTCCAGC GCCTGCTGGC CCTGGACCCG GAGAAGCGCT GCCCGGTCAA GGAGGCCTTC 900

CACTTCATCA AGTACGAGCT GGTGACGGAA GCCCGCCGCC GGCCCTCCTG CCGCGGCCGC 960

CGGCCCGCCG GGGACAAGCT CTCGGCCGGG CCCCTCCGCC ACGAGACCCC CACCTCCTGC 1020

ACCCCCGCCC CTCTGAAGCG GACCGTCCTG ACCGAGAGCG GAGGCGGGCC CTGCCTCTCC 1080

TCCGCCGACT CCAGCCTGCC GTCCCCGGGG CCTCCCGGCA GGACGGACGG CCGCCAGGAC 1140

AAGGGCAAGG GCCAGATGGT CTTGGCCACA GCAATAGAGA TATGCGTCTA G 1191

Domain Profile

S: 1     yelvrklgeGsfgkvlLvehrqsgtkvalKllpkektklkdFlrEfsvglslsshsaivk  60

         y+l+r+lg+G++gkv+Lv+h+ +gtk+alK+++k+ktklk+FlrEfs++++lss+++i+k

Q: 43    YDLIRELGKGTYGKVDLVSHKSTGTKMALKFVNKSKTKLKNFLREFSITNTLSSSPFIIK  102

         99**********************************************************

S: 61    tydvaletadayvFaqEyaplgdLaeaiqekvGlpeaavkrvvaqlasAldflHsrnlvh  120

         ++dv++et+d+yvFaqEyap gdL+++i+++vGlpe++vkr+v+ql+ Ald++Hs++lvh

Q: 103   VFDVVFETEDCYVFAQEYAPGGDLFDIIPPQVGLPEDMVKRCVQQLGLALDYMHSKHLVH  162

         ************************************************************

S: 121   rdlKpenvLvfdpdcsrvkltDfGltrkkgslvkkkeevipytapelcelvkeeklkvdp  180

         rd+KpenvL+fd+dc+rvkl+DfG+trk g++vk+++ +ipytape+c++ ++e+l+vd+

Q: 163   RDIKPENVLLFDRDCRRVKLADFGMTRKAGCRVKRVSGTIPYTAPEVCRAGRAEGLAVDT  222

         ************************************************************

S: 181   svDvWalGvllfvvltgkfPWdkasleadpfyeeflkwqkrklrklPkkfkrlsekalrl  240

         s DvWa+Gvl+f+vltg+fPW++a +++d+f+eef++wq+++l  lP++++r++++alr+

Q: 223   SIDVWAFGVLIFCVLTGNFPWEAA-SATDAFFEEFVRWQRGRLAGLPSQWRRFTDHALRM  281

         ************************.99*********************************

S: 241   lkklldlepedrskakevakf  261

         +++ll+l+pe+r+++ke ++f

Q: 282   FQRLLALDPEKRCPVKEAFHF  302

         ****************99887

Domain Sequence
(FASTA)

YDLIRELGKG TYGKVDLVSH KSTGTKMALK FVNKSKTKLK NFLREFSITN TLSSSPFIIK 60

VFDVVFETED CYVFAQEYAP GGDLFDIIPP QVGLPEDMVK RCVQQLGLAL DYMHSKHLVH 120

RDIKPENVLL FDRDCRRVKL ADFGMTRKAG CRVKRVSGTI PYTAPEVCRA GRAEGLAVDT 180

SIDVWAFGVL IFCVLTGNFP WEAASATDAF FEEFVRWQRG RLAGLPSQWR RFTDHALRMF 240

QRLLALDPEK RCPVKEAFHF 260

Keyword

ATP-binding; Complete proteome; Cytoplasm; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.
IPR016234	; Ser/Thr_kinase_Sbk1.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013