EKS-ORA-00374

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORA-00374

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/WEE	334.4	5.1E-100	54	329	276

Status

Unreviewed

Ensembl Protein

ENSOANP00000014678

UniProt Accession

F7G6K4;

Protein Name

Protein Synonyms/Alias

Gene Name

WEE2

Gene Synonyms/Alias

WEE2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOANG00000009220	ENSOANP00000014678	ENSOANT00000014681

Organism

Ornithorhynchus anatinus

Functional Description

Protein Length

409

Protein Sequence
(FASTA)

WRNECRSGTE DESGGLLAAP GVTLSVRNTH RAPLPSQRSV LRESNMVSRY DTEFLELEKI 60

GVGEFGSVFK CIKRLDGCIY AIKRSTRPLA GSLNELAALR EVYAHAVLGH HPHVVRYYSA 120

WAEDDHIIIQ NEHCNGGSLQ DLVLASKRSG QLLPEPELKN ILLQVSLGLR GIHNSDLVHL 180

DLKPSNIFIC RKLTGESPAV LEEGETEDDC FLSASVMYKI GDLGHVTSIR NPQVEEGDSR 240

FLAKEILQEK EYRFLPKADV FALGLTVAVA AGAEDLPLNG TSWHHIRQGN LPPIPQRLSE 300

DFYNLLKLTI DPDPAARPTA AALTRHPVLR PSLGRAAELR QQLDMEKVRT AKLESELRAT 360

RMLESLKQDL RQGGSRPSAP RAAPARPKGS RRLVGGKNAR SLSLTFMGY 409

Nucleotide Sequence
(FASTA)

TGGAGAAATG AATGTCGCTC AGGCACTGAA GATGAGAGTG GTGGTTTGCT GGCAGCTCCC 60

GGGGTCACGC TGTCTGTGAG GAACACTCAC CGGGCCCCCC TTCCCTCTCA GAGAAGCGTC 120

TTGCGTGAGA GCAACATGGT CTCCCGCTAC GACACGGAAT TCCTGGAGCT GGAGAAGATC 180

GGGGTCGGGG AGTTCGGCTC CGTGTTCAAG TGCATCAAGA GGCTGGATGG GTGCATCTAT 240

GCAATCAAAC GCTCCACGAG GCCTCTGGCA GGGTCCTTAA ATGAGCTCGC AGCGCTGCGG 300

GAAGTGTACG CCCACGCCGT GCTAGGACAT CACCCCCACG TGGTACGTTA CTACTCCGCT 360

TGGGCAGAGG ATGATCACAT AATCATCCAG AACGAGCACT GCAATGGTGG GAGCCTGCAG 420

GATTTGGTGC TGGCAAGCAA GAGGAGCGGC CAGCTCCTTC CGGAGCCCGA GCTCAAGAAC 480

ATCCTGCTGC AAGTCTCCCT GGGCCTTCGG GGTATCCACA ACTCTGACCT GGTGCACCTG 540

GACCTCAAAC CCAGTAATAT CTTCATCTGC CGTAAGCTGA CCGGTGAATC CCCCGCTGTT 600

CTGGAGGAGG GGGAGACTGA GGATGACTGC TTCCTGTCTG CCAGCGTGAT GTACAAAATC 660

GGTGACCTGG GCCACGTGAC TTCCATCAGA AACCCCCAAG TGGAGGAAGG AGACAGCCGT 720

TTCTTGGCCA AGGAGATTCT GCAAGAGAAG GAGTATCGCT TCCTGCCCAA GGCCGACGTG 780

TTCGCCCTGG GGCTCACCGT CGCCGTGGCC GCCGGAGCGG AGGACTTGCC GCTCAACGGG 840

ACCTCGTGGC ATCACATCCG CCAGGGCAAC CTGCCCCCCA TCCCCCAGCG GCTTTCTGAA 900

GACTTCTACA ACCTGCTGAA GCTCACGATC GACCCCGACC CCGCGGCGAG ACCTACGGCG 960

GCGGCTCTGA CCAGGCACCC CGTGCTCCGG CCCTCGCTGG GGCGAGCGGC GGAGCTCCGC 1020

CAGCAGCTGG ACATGGAGAA GGTGCGGACC GCCAAGCTGG AGAGCGAACT CCGAGCCACC 1080

CGGATGCTCG AGAGCCTCAA GCAAGACCTC CGCCAAGGCG GCTCCAGGCC CTCTGCCCCC 1140

CGAGCTGCCC CGGCCCGGCC CAAGGGCTCT CGGCGCTTGG TGGGAGGGAA GAACGCCCGC 1200

TCTCTGAGCC TCACCTTCAT GGGCTACTGA 1230

Domain Profile

S: 1     FeevekiGkGefgevfkvvkredgklyAikkskkplkglskekkalrEvtahavlgqhen  60

         F e+ekiG+Gefg+vfk++kr+dg++yAik+s +pl+g+ +e  alrEv+ahavlg+h++

Q: 54    FLELEKIGVGEFGSVFKCIKRLDGCIYAIKRSTRPLAGSLNELAALREVYAHAVLGHHPH  113

         7899********************************************************

S: 61    vvryisaWeeddslyiqtElCeggsLeaalqeceakkkaleeaelkkilldlllglrylH  120

         vvry+saW+edd+++iq+E C+ggsL++ +   +++ + l+e elk+ill+++lglr +H

Q: 114   VVRYYSAWAEDDHIIIQNEHCNGGSLQDLVLASKRSGQLLPEPELKNILLQVSLGLRGIH  173

         ************************************************************

S: 121   ssslvHlDikpenifi.......................tkevtlklgDlGlvtelnsed  157

         +s+lvHlD+kp+nifi                       +++v++k+gDlG+vt++

Q: 174   NSDLVHLDLKPSNIFIcrkltgespavleegeteddcflSASVMYKIGDLGHVTSI---R  230

         ********************************************************...9

S: 158   kskveEGDsrylakEilqeeyskl..kaDiFslgltilevaanvelPsnGeaWhklRkgk  215

         +++veEGDsr+lakEilqe+ +++  kaD+F+lglt++++a++++lP nG++Wh++R+g+

Q: 231   NPQVEEGDSRFLAKEILQEKEYRFlpKADVFALGLTVAVAAGAEDLPLNGTSWHHIRQGN  290

         9******************999888***********************************

S: 216   lpdeilkelsedlrellklmlepdperRptaeellkhevl  255

         lp  i + lsed+ +llkl ++pdp+ Rpta++l +h+vl

Q: 291   LP-PIPQRLSEDFYNLLKLTIDPDPAARPTAAALTRHPVL  329

         **.9*********************************986

Domain Sequence
(FASTA)

FLELEKIGVG EFGSVFKCIK RLDGCIYAIK RSTRPLAGSL NELAALREVY AHAVLGHHPH 60

VVRYYSAWAE DDHIIIQNEH CNGGSLQDLV LASKRSGQLL PEPELKNILL QVSLGLRGIH 120

NSDLVHLDLK PSNIFICRKL TGESPAVLEE GETEDDCFLS ASVMYKIGDL GHVTSIRNPQ 180

VEEGDSRFLA KEILQEKEYR FLPKADVFAL GLTVAVAAGA EDLPLNGTSW HHIRQGNLPP 240

IPQRLSEDFY NLLKLTIDPD PAARPTAAAL TRHPVL 276

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005813	; C:centrosome
GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007343	; P:egg activation
GO:0007143	; P:female meiosis
GO:0035038	; P:female pronucleus assembly
GO:0007137	; P:meiotic metaphase II
GO:0007128	; P:meiotic prophase I
GO:0060283	; P:negative regulation of oocyte development
GO:0060631	; P:regulation of meiosis I

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013