EKS-ORA-00257

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORA-00257

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/BUB	193.5	4.4E-57	738	1008	271

Status

Unreviewed

Ensembl Protein

ENSOANP00000016996

UniProt Accession

F6RG50;

Protein Name

Protein Synonyms/Alias

Gene Name

BUB1B

Gene Synonyms/Alias

BUB1B;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOANG00000010717	ENSOANP00000016996	ENSOANT00000016999

Organism

Ornithorhynchus anatinus

Functional Description

Protein Length

1033

Protein Sequence
(FASTA)

AMAQGGDEWE LSKENVQPLR QGRIMSTLQG ALAQQETTSY STIQQQKQAF ESEIRFYTGD 60

DPLDVWDRYI RWIEQTFPQG GKESKLSALL ERAVKVLQEE RRYYNDPRFL SLWLKLGHTC 120

NEPLDMYSYL HSQGIGIGLA QLYIAWAEAY EVREDYRKAE QVFQKGLQCK AEPQDRLQSQ 180

HRQFQARVSR QTLWALERGA LGPHRTSLAE LKSRGKKTAR APINRVGGAL RDAGQSRGLP 240

NTAPPQRPNG SQFMVFDENG GGPSWTEPPG LSTQPWAAPP VPRDKENELK PGPWNNARVR 300

HGAGMGEEGR EMAAFRLVPG FTPYVEESAQ QQVMTPCKIE PSINHVLSTW KPGKEAGDAL 360

QRVQSHQKEA HEKKEVVMYC KEKVYASVEE FSLEEIRAEI WWKKLNKKRD EELLAREHKR 420

AEMQKQIEQM EQLLKEIKAT QEQRPGDEET PEDTVPASTQ YPEGAPAEQL FGPQSSSPVC 480

QALKASLQTD NGRQNWPCPL GADPLDSGGS GVPFSIFDES EAVNNPCASL PANPQQLPTR 540

RRPLAVRRHS EGIASKDDGT PEATGELVGV EPLSEEAIIT GSYRNVTICP DPEDTCDFLQ 600

AAHLASTPFH GVVALNGPLA GDAKRVPQEA VGSHAVREAT YPEELTNKKL SPIMEESSQE 660

MTRSSGALGS SSSSVSGLST IKDLQIPEKL ELANETEETS PPSPWCPEQH RRLLVSLPEL 720

SSFPGFCSEP GPMPEVEVDK VVKLGKESYC IKKAVLTGDA CKTFWGVQID SSCVALKAVA 780

IKVYSQPAPW DFYITVRLKE RLEAEFGWGF SERCSCLHFQ DGCIVLHQDL NPFTLSDLLP 840

HTESNAHELA LLVAHTLLGL VEKLQRADIV HGDLSPQTLI LGDRICAGFH CAEDSSVLRI 900

VDFSHAVDLR ARPGIRSLGG FPTVQALEGQ KILAHCTSPY QVDLLGIADV AHLLLFREHL 960

QVRQACSHWT LSQNLSGLKG GGLWKAFFER ILNADGEASV SVVSELRQGL NEKLDSCWSS 1020

LQAAFWELEG LLS 1033

Nucleotide Sequence
(FASTA)

GCGATGGCCC AAGGAGGGGA CGAGTGGGAG CTGAGTAAGG AGAACGTGCA GCCACTGAGG 60

CAGGGGCGGA TTATGTCCAC CCTGCAGGGA GCCCTGGCCC AGCAGGAGAC GACCAGCTAC 120

AGCACCATCC AGCAGCAGAA ACAGGCCTTT GAGTCGGAAA TCCGCTTCTA CACCGGGGAC 180

GACCCGCTGG ACGTTTGGGA CAGGTACATC CGGTGGATCG AGCAGACCTT CCCTCAGGGA 240

GGGAAGGAGA GCAAACTGTC CGCGCTGCTT GAGAGAGCCG TGAAAGTGCT CCAGGAGGAA 300

CGGCGCTACT ACAACGACCC TCGCTTCCTC AGCCTCTGGC TCAAGCTGGG TCACACGTGC 360

AACGAACCCC TGGACATGTA CAGCTACTTA CACAGCCAAG GGATCGGCAT CGGTCTGGCC 420

CAGCTCTACA TCGCCTGGGC GGAAGCATAC GAGGTCAGGG AGGACTATCG GAAGGCGGAG 480

CAGGTGTTCC AGAAAGGACT TCAGTGCAAG GCGGAGCCCC AGGACAGGCT GCAATCCCAG 540

CATCGACAGT TCCAGGCCCG CGTGTCTCGG CAAACGCTGT GGGCCCTCGA GAGAGGGGCC 600

TTGGGCCCTC ACCGAACTTC CCTGGCTGAG CTGAAGAGCA GAGGGAAAAA GACAGCCAGA 660

GCCCCCATCA ACCGAGTGGG AGGGGCTCTG AGAGACGCAG GCCAGAGCCG AGGGCTCCCG 720

AACACAGCTC CTCCACAGAG ACCCAATGGT TCCCAGTTCA TGGTGTTTGA TGAGAATGGC 780

GGGGGACCCT CTTGGACAGA ACCCCCCGGG CTCAGCACCC AGCCTTGGGC CGCCCCCCCG 840

GTGCCCAGGG ACAAGGAGAA TGAGCTGAAG CCCGGCCCGT GGAACAATGC CCGGGTAAGG 900

CACGGGGCCG GGATGGGTGA GGAGGGGCGG GAGATGGCTG CCTTTCGCCT CGTCCCTGGC 960

TTCACCCCAT ACGTGGAGGA GTCCGCCCAG CAGCAAGTCA TGACCCCGTG TAAAATCGAA 1020

CCCAGCATAA ACCATGTGCT GAGCACCTGG AAGCCCGGGA AGGAGGCGGG GGACGCCCTG 1080

CAGCGAGTCC AGAGCCACCA GAAGGAGGCA CATGAGAAGA AGGAGGTGGT AATGTACTGC 1140

AAGGAGAAGG TCTATGCCAG CGTGGAAGAG TTCTCCTTGG AGGAGATCCG GGCTGAGATC 1200

TGGTGGAAGA AATTGAACAA GAAGAGGGAC GAGGAGCTGC TGGCCCGTGA GCACAAGAGG 1260

GCAGAGATGC AGAAGCAGAT CGAGCAGATG GAGCAGTTGC TAAAGGAGAT CAAAGCTACC 1320

CAGGAGCAGA GGCCAGGAGA TGAGGAAACC CCCGAGGATA CTGTGCCCGC TTCCACCCAG 1380

TACCCCGAGG GAGCCCCTGC CGAGCAGTTG TTTGGACCTC AGAGCTCATC TCCTGTATGC 1440

CAAGCACTGA AGGCATCTCT TCAAACAGAC AACGGTAGAC AGAATTGGCC ATGCCCTCTG 1500

GGTGCAGATC CGCTGGACTC CGGAGGCTCT GGTGTTCCCT TCTCCATCTT TGATGAGTCT 1560

GAGGCAGTCA ACAATCCCTG TGCCAGCCTC CCAGCCAATC CCCAGCAGCT GCCCACCAGA 1620

CGGCGGCCCC TCGCCGTTCG GCGACACTCT GAAGGCATCG CCTCAAAGGA TGATGGAACA 1680

CCAGAAGCCA CGGGCGAGCT GGTGGGCGTC GAGCCCCTGA GCGAAGAGGC CATCATCACC 1740

GGCTCCTACA GGAACGTCAC CATCTGCCCC GACCCGGAAG ACACCTGCGA TTTCCTCCAG 1800

GCCGCCCACC TGGCGTCAAC TCCCTTTCAT GGCGTGGTGG CGCTCAATGG CCCTCTCGCT 1860

GGTGATGCCA AGAGGGTCCC CCAGGAAGCT GTGGGCTCAC ATGCCGTCAG GGAGGCCACT 1920

TATCCCGAAG AACTCACCAA TAAGAAGCTG AGCCCGATCA TGGAGGAGAG CAGTCAGGAA 1980

ATGACCCGCT CCTCGGGGGC CTTGGGCTCC TCCTCCTCCT CGGTCAGCGG ACTCTCCACC 2040

ATCAAGGACC TGCAGATCCC CGAGAAACTG GAGCTCGCCA ACGAAACCGA GGAAACCTCC 2100

CCTCCATCTC CCTGGTGCCC AGAACAGCAC AGGCGGCTGC TGGTATCACT GCCGGAGTTG 2160

TCTTCCTTCC CAGGCTTTTG TTCTGAGCCC GGGCCCATGC CTGAAGTGGA AGTAGATAAA 2220

GTGGTGAAAC TAGGCAAGGA AAGCTACTGC ATCAAGAAAG CTGTCCTGAC GGGGGATGCC 2280

TGTAAGACCT TTTGGGGTGT CCAAATTGAC TCTTCGTGTG TGGCCTTGAA AGCGGTGGCG 2340

ATCAAGGTGT ATTCCCAGCC GGCCCCGTGG GACTTCTACA TCACGGTCCG GTTGAAGGAG 2400

CGGCTGGAGG CCGAGTTCGG CTGGGGTTTC AGCGAGCGGT GCAGCTGTCT CCACTTCCAG 2460

GACGGCTGCA TTGTCCTGCA CCAGGACCTA AACCCCTTCA CCCTGTCGGA TCTCCTCCCT 2520

CACACTGAGT CGAATGCCCA CGAGCTGGCC CTGCTGGTCG CCCACACTCT CCTGGGCCTG 2580

GTGGAGAAGC TGCAGAGAGC CGACATCGTC CACGGAGACC TGAGCCCCCA GACCCTCATC 2640

CTGGGTGACA GGATCTGTGC CGGGTTCCAC TGTGCCGAGG ACAGCAGCGT GCTGCGGATC 2700

GTGGACTTCT CCCACGCCGT GGACCTGAGG GCCCGGCCCG GCATCCGCTC GCTCGGCGGC 2760

TTCCCGACAG TGCAGGCCCT GGAGGGGCAG AAGATCCTGG CCCACTGCAC CTCGCCCTAT 2820

CAGGTAGACC TGCTTGGTAT TGCCGACGTA GCCCACTTAC TGCTGTTCCG AGAGCACCTG 2880

CAGGTCCGCC AGGCTTGTTC CCACTGGACG CTCAGCCAGA ATCTCTCCGG GCTCAAAGGC 2940

GGAGGGCTGT GGAAGGCGTT TTTTGAGCGG ATTCTGAATG CCGATGGGGA GGCCTCGGTG 3000

TCGGTCGTGA GCGAGCTGAG ACAGGGGCTG AATGAGAAGC TGGATTCCTG CTGGAGTTCC 3060

CTTCAGGCTG CCTTCTGGGA GCTGGAAGGA CTCCTGAGCT GA 3102

Domain Profile

S: 3     iekeigeGayakvykaeh....dsk.............sgelvalKvekpansWefYIcl  45

         ++k +  G + +++k+                        + va+Kv +++ +W+fYI+

Q: 738   VDKVVKLGKESYCIKKAVltgdA-CktfwgvqidsscvALKAVAIKVYSQPAPWDFYITV  796

         66666666666666666544431.134444444444768899******************

S: 46    qlkeRlkeeellksiieissallfqdasllvleyasygtlldlinkvkevtnkvmdeelv  105

         +lkeRl+  e   ++ e +s+l fqd+++++++  + +tl dl+ ++++ +     +el

Q: 797   RLKERLE-AEFGWGFSERCSCLHFQDGCIVLHQDLNPFTLSDLLPHTESNA-----HELA  850

         ******9.569****************************************.....****

S: 106   vllivqllkiveklHeveIiHgDlkPdnfllgnrimdkadkdkeekglkliDfgrsiDmk  165

         +l++  ll +vekl +++I+HgDl+P++++lg ri    ++ ++++ l+++Df+ ++D++

Q: 851   LLVAHTLLGLVEKLQRADIVHGDLSPQTLILGDRICAGFHCAEDSSVLRIVDFSHAVDLR  910

         ************************************************************

S: 166   llpdgtkfkgkaktdafeciemlagkswsYqvDlfglaavihvllfgkyleviqeggswk  225

           p    + g+ +++a+e++++la + ++YqvDl+g+a+v+h+llf ++l+v q  ++w

Q: 911   ARPGIRSLGGFPTVQALEGQKILAHCTSPYQVDLLGIADVAHLLLFREHLQVRQACSHWT  970

         ************************************************************

S: 226   lkqkikrllkkelwekiferlLNisdastlpsleelve  263

         l+q+++ l+   lw+ +fer+LN++ +++++++ el++

Q: 971   LSQNLSGLKGGGLWKAFFERILNADGEASVSVVSELRQ  1008

         ***********************************995

Domain Sequence
(FASTA)

VDKVVKLGKE SYCIKKAVLT GDACKTFWGV QIDSSCVALK AVAIKVYSQP APWDFYITVR 60

LKERLEAEFG WGFSERCSCL HFQDGCIVLH QDLNPFTLSD LLPHTESNAH ELALLVAHTL 120

LGLVEKLQRA DIVHGDLSPQ TLILGDRICA GFHCAEDSSV LRIVDFSHAV DLRARPGIRS 180

LGGFPTVQAL EGQKILAHCT SPYQVDLLGI ADVAHLLLFR EHLQVRQACS HWTLSQNLSG 240

LKGGGLWKAF FERILNADGE ASVSVVSELR Q 271

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>

Gene Ontology

GO:0000940	; C:condensed chromosome outer kinetochore
GO:0048471	; C:perinuclear region of cytoplasm
GO:0016772	; F:transferase activity, transferring phosphorus-containing groups
GO:0007091	; P:mitotic metaphase/anaphase transition
GO:0034501	; P:protein localization to kinetochore

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR013212	; Mad3_BUB1_I.
IPR015661	; Ser/Thr_kinase_Bub1.

Pfam

PF08311

; Mad3_BUB1_I; 1.

SMARTs

SM00777

; Mad3_BUB1_I; 1.

Prosites

PS51489

; BUB1_N; 1.

Prints

Created Date

20-Feb-2013