EKS-ORA-00054

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORA-00054

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	332.1	3.0E-99	4	288	285

Status

Unreviewed

Ensembl Protein

ENSOANP00000017065

UniProt Accession

F6Y2P0;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK20

Gene Synonyms/Alias

CDK20;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOANG00000010766	ENSOANP00000017065	ENSOANT00000017068

Organism

Ornithorhynchus anatinus

Functional Description

Protein Length

345

Protein Sequence
(FASTA)

MDQYSILGRI GEGAHGIVFK AKHVETGETV ALKKVALRKL EDGIPNQALR EIKALQEIED 60

NQYVVKLKAV FPHGAGFVLA FEFMLSDLSE VIRHAHRPLG QAQVKGYMQM LLKGVAFCHA 120

NNIMHRDLKP ANLLISSSGQ LKIADFGLAR VFSRSGDRLY SHQVATRWYR APELLYGARQ 180

YDEGVDLWAV GCILGELLNG SPLFPGENDI EQLCCVLRVL GTPSPRVWPE ITELPDYNKI 240

SFKEQAPLPL EEVLPDAAPQ ALQLLSRFLL YPPRQRIPAA QALLHQYFFT APLPAHPSEL 300

PIPQRGGPGP KARQGPPHTR DFHVEQPLEE SLLDPKLIRP YLPEG 345

Nucleotide Sequence
(FASTA)

ATGGACCAGT ACAGCATCCT CGGCCGCATT GGCGAGGGCG CCCACGGTAT CGTCTTCAAA 60

GCCAAACACG TGGAGACTGG TGAGACAGTG GCTCTTAAGA AAGTGGCTCT GCGGAAACTG 120

GAAGATGGAA TCCCCAACCA GGCGCTGCGG GAGATCAAGG CTCTACAGGA GATTGAGGAT 180

AATCAGTATG TGGTGAAGCT GAAGGCCGTG TTCCCTCATG GCGCGGGCTT TGTCCTGGCC 240

TTCGAATTCA TGCTGTCCGA CCTGTCCGAG GTGATCCGCC ACGCCCATAG GCCGCTGGGC 300

CAGGCCCAGG TCAAGGGCTA CATGCAGATG CTGCTCAAGG GGGTCGCCTT CTGCCACGCT 360

AACAACATCA TGCACCGGGA CCTGAAGCCA GCCAATCTGC TCATCAGCTC CTCGGGCCAG 420

CTTAAGATTG CTGACTTTGG CCTGGCTCGG GTCTTCTCCC GCAGTGGGGA CCGGCTCTAC 480

AGCCACCAAG TGGCCACCAG GTGGTACCGG GCCCCAGAAC TCCTGTATGG CGCCCGGCAG 540

TACGATGAGG GAGTCGACCT GTGGGCGGTG GGTTGCATCC TGGGGGAACT GCTCAACGGC 600

TCACCCCTGT TCCCTGGAGA AAATGACATC GAGCAGCTGT GCTGTGTGCT GCGCGTCCTG 660

GGCACCCCCA GCCCCAGGGT CTGGCCGGAG ATCACAGAGC TTCCCGACTA CAACAAGATC 720

TCCTTCAAGG AGCAGGCGCC ATTGCCCCTG GAGGAGGTGC TGCCCGACGC CGCCCCCCAG 780

GCTCTGCAGC TGCTCAGCCG CTTCCTGCTC TATCCCCCGC GCCAGCGCAT CCCGGCTGCC 840

CAGGCCCTGC TGCACCAGTA CTTCTTCACG GCCCCGCTGC CGGCTCACCC TTCGGAGCTG 900

CCGATTCCCC AGCGAGGGGG GCCGGGTCCC AAGGCCCGCC AAGGGCCCCC CCACACGCGC 960

GACTTCCACG TGGAGCAGCC GCTGGAGGAG TCGCTCCTGG ATCCTAAGCT GATCCGACCG 1020

TATCTCCCCG AAGGCTGA 1038

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkel.khkn  59

         y+ l +igeG++g v+kak+ etge+vAlKk++l k ++g+p +alrEi+ l+e+ ++++

Q: 4     YSILGRIGEGAHGIVFKAKHVETGETVALKKVALRKLEDGIPNQALREIKALQEIeDNQY  63

         778899*************************************************77899

S: 60    ivkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsn  119

         +vkL+ v+  + + ++L fef+ +dL++++++ ++  l +++vk ++++ll+g+a++H+n

Q: 64    VVKLKAVFP-HGAGFVLAFEFMLSDLSEVIRHAHR-PLGQAQVKGYMQMLLKGVAFCHAN  121

         *********.99*******************9999.************************

S: 120   kilHRDlKpqNlLiskegklklaDfGlarafssplkt.ytkevvTlwYraPelLlgakeY  178

         +i+HRDlKp+NlLis++g+lk+aDfGlar fs   ++ y+++v T+wYraPelL+ga++Y

Q: 122   NIMHRDLKPANLLISSSGQLKIADFGLARVFSRSGDRlYSHQVATRWYRAPELLYGARQY  181

         *******************************8877755**********************

S: 179   stavDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ks  237

         ++ vD+W+vgcil ell+ +plf+g+++i+ql  ++++lgtps +vwpe+++lp+y+  s

Q: 182   DEGVDLWAVGCILGELLNGSPLFPGENDIEQLCCVLRVLGTPSPRVWPEITELPDYNkIS  241

         *********************************************************889

S: 238   fpkkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         f+++++  l+e++++++ +al+ll+++l + p++Ri a +al h+yf

Q: 242   FKEQAPLPLEEVLPDAAPQALQLLSRFLLYPPRQRIPAAQALLHQYF  288

         ***9999***************************************9

Domain Sequence
(FASTA)

YSILGRIGEG AHGIVFKAKH VETGETVALK KVALRKLEDG IPNQALREIK ALQEIEDNQY 60

VVKLKAVFPH GAGFVLAFEF MLSDLSEVIR HAHRPLGQAQ VKGYMQMLLK GVAFCHANNI 120

MHRDLKPANL LISSSGQLKI ADFGLARVFS RSGDRLYSHQ VATRWYRAPE LLYGARQYDE 180

GVDLWAVGCI LGELLNGSPL FPGENDIEQL CCVLRVLGTP SPRVWPEITE LPDYNKISFK 240

EQAPLPLEEV LPDAAPQALQ LLSRFLLYPP RQRIPAAQAL LHQYF 285

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013