EPS-ORA-00031

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-ORA-00031

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPP/PP5	385.1	2.3E-115	210	405	196

Status

Unreviewed

Ensembl Protein

ENSOANP00000018930

UniProt Accession

F7BJN3;

Protein Name

Protein Synonyms/Alias

Gene Name

PPP5C

Gene Synonyms/Alias

PPP5C;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOANG00000011946	ENSOANP00000018931	ENSOANT00000018934
ENSOANG00000011946	ENSOANP00000018930	ENSOANT00000018933

Organism

Ornithorhynchus anatinus

Functional Description

Protein Length

408

Protein Sequence
(FASTA)

KDYDNAIKLY SQAIEINPSN AVYHGNRSLA YLRTECYGYA LADATRAIEL DKKYIKGYYR 60

RAASNMALGK FKAALRDYET PALVGPAAPG LPIRPSSLTG RGLSPVLLSA VPRTTPPPQI 120

GCTLSSPLLS SAHLHVAQAP ALTGPGPSSL STVPTLTPTG RARVPCLPPP LARMCSPSPC 180

MAPPWLARAI ALGWQGQGRH RVFPPHPFPS GNHEPDNMNQ IYGFEGEVKA KYTAQMFQLF 240

SEVFEWLPLA QCINGKVLIM HGGLFSEDGV TLDDIRKIER NRQPPDSGPM CDLLWSDPQP 300

QNGRSVSKRG VSCQFGPDVT KSFLEENQLD YIIRSHEVKA EGYEVTHGGK CITVFSAPNY 360

CDQMGNKASY IHLSGADLRP QFHQFTAVPH PNVKPMAYAN TLLQLGMM 408

Nucleotide Sequence
(FASTA)

AAGGACTACG ACAACGCCAT CAAGTTGTAC AGTCAGGCCA TCGAGATTAA CCCCAGCAAC 60

GCCGTCTACC ATGGGAACCG CAGCCTGGCC TACCTGCGCA CCGAGTGCTA CGGCTACGCT 120

CTGGCCGACG CCACCAGGGC CATCGAGCTG GACAAGAAAT ACATCAAAGG CTACTATCGC 180

CGGGCGGCCA GCAACATGGC CCTGGGCAAG TTCAAAGCCG CCCTACGCGA CTACGAGACG 240

CCCGCCCTGG TGGGACCGGC CGCACCCGGT CTTCCCATCC GGCCCTCCTC CCTGACTGGC 300

CGTGGCCTGT CCCCCGTCCT CCTCTCGGCT GTGCCCAGGA CCACACCCCC CCCCCAGATT 360

GGCTGCACCC TCTCATCCCC CCTACTTAGC TCTGCTCACC TCCATGTTGC CCAGGCCCCT 420

GCCCTGACTG GCCCTGGCCC ATCATCCCTC TCAACGGTGC CCACCCTCAC CCCGACTGGC 480

CGCGCCCGGG TGCCGTGCCT CCCCCCACCC CTCGCTCGAA TGTGCTCACC GTCACCGTGT 540

ATGGCCCCCC CTTGGCTGGC CAGAGCCATC GCCCTAGGGT GGCAGGGCCA GGGGCGGCAT 600

CGTGTGTTCC CGCCCCATCC CTTCCCTTCA GGGAACCACG AGCCAGACAA CATGAACCAG 660

ATCTACGGCT TCGAGGGCGA GGTTAAGGCC AAGTACACGG CGCAGATGTT CCAGCTGTTC 720

AGTGAAGTGT TCGAGTGGCT GCCCCTGGCC CAGTGCATCA ACGGCAAAGT GCTGATCATG 780

CACGGAGGCC TGTTCAGCGA GGACGGGGTC ACCCTCGACG ACATCCGCAA GATCGAGCGC 840

AATAGGCAGC CGCCAGACTC AGGGCCCATG TGTGACTTGC TGTGGTCGGA CCCCCAGCCC 900

CAGAACGGCC GTTCGGTCAG CAAGCGCGGG GTCAGCTGTC AGTTTGGGCC GGATGTGACC 960

AAGAGCTTCC TGGAGGAGAA CCAGCTGGAT TACATCATCC GCAGCCACGA GGTCAAGGCC 1020

GAGGGCTACG AGGTGACCCA CGGCGGCAAG TGCATCACCG TCTTCTCGGC CCCCAACTAC 1080

TGTGATCAGA TGGGCAACAA AGCATCCTAC ATCCACCTCA GCGGGGCCGA CCTGCGGCCG 1140

CAGTTCCACC AGTTCACAGC AGTGCCTCAT CCCAACGTCA AGCCCATGGC CTACGCCAAC 1200

ACCCTGCTGC AGCTGGGCAT GATGTGA 1227

Domain Profile

S: 118   rGnhesdnmnkiyGfegevkakytaklyelfaevfewlPlaqlingkvlvmhGGlfsedg  177

          Gnhe dnmn+iyGfegevkakyta++++lf+evfewlPlaq+ingkvl+mhGGlfsedg

Q: 210   SGNHEPDNMNQIYGFEGEVKAKYTAQMFQLFSEVFEWLPLAQCINGKVLIMHGGLFSEDG  269

         6***********************************************************

S: 178   vtlddirkiernaqPPeeGalcellWsdPqeanGrgvskrGvglqfGpdvtkrfleenkl  237

         vtlddirkiern+qPP++G++c+llWsdPq++nGr+vskrGv++qfGpdvtk fleen+l

Q: 270   VTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSVSKRGVSCQFGPDVTKSFLEENQL  329

         ************************************************************

S: 238   dyiirshevkaegveveqkgklvtvfsapnycdsqgnlasvihvrnddlrliietfeave  297

         dyiirshevkaeg+ev+++gk++tvfsapnycd++gn+as+ih+ + dlr+++++f+av+

Q: 330   DYIIRSHEVKAEGYEVTHGGKCITVFSAPNYCDQMGNKASYIHLSGADLRPQFHQFTAVP  389

         ************************************************************

S: 298   hpdvkpmaysngllgl  313

         hp+vkpmay+n+ll+l

Q: 390   HPNVKPMAYANTLLQL  405

         *************997

Domain Sequence
(FASTA)

SGNHEPDNMN QIYGFEGEVK AKYTAQMFQL FSEVFEWLPL AQCINGKVLI MHGGLFSEDG 60

VTLDDIRKIE RNRQPPDSGP MCDLLWSDPQ PQNGRSVSKR GVSCQFGPDV TKSFLEENQL 120

DYIIRSHEVK AEGYEVTHGG KCITVFSAPN YCDQMGNKAS YIHLSGADLR PQFHQFTAVP 180

HPNVKPMAYA NTLLQL 196

Keyword

Complete proteome; Reference proteome; TPR repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005829	; C:cytosol
GO:0005794	; C:Golgi apparatus
GO:0005634	; C:nucleus
GO:0004721	; F:phosphoprotein phosphatase activity
GO:0004871	; F:signal transducer activity
GO:0043123	; P:positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0006470	; P:protein dephosphorylation
GO:0043278	; P:response to morphine

KEGG

InterPros

IPR004843	; Metallo_PEstase_dom.
IPR006186	; Ser/Thr-sp_prot-phosphatase.
IPR011236	; Ser/Thr_PPase_5.
IPR001440	; TPR-1.
IPR013026	; TPR-contain_dom.
IPR011990	; TPR-like_helical.
IPR019734	; TPR_repeat.

Pfam

PF00149	; Metallophos; 1.
PF00515	; TPR_1; 1.

SMARTs

SM00156

; PP2Ac; 1.

Prosites

PS50005	; TPR; 3.
PS50293	; TPR_REGION; 1.

Prints

PR00114

; STPHPHTASE.

Created Date

20-Feb-2013