EKS-ORA-00076

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORA-00076

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/PIKK	403.7	7.6E-121	2100	2420	321

Status

Unreviewed

Ensembl Protein

ENSOANP00000019351

UniProt Accession

F7FGW0;

Protein Name

Protein Synonyms/Alias

Gene Name

SMG1

Gene Synonyms/Alias

SMG1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOANG00000012229	ENSOANP00000019351	ENSOANT00000019354

Organism

Ornithorhynchus anatinus

Functional Description

Protein Length

3637

Protein Sequence
(FASTA)

MFFSDFCRTD SAPADQDHLK YSSSRDRGSS ASYGLQPSNS VVVSRQRHDD IRVHTDIQNE 60

EKGGYNVNGG AGENTYGRKS LGQELRVNNV TNPDFTSVQH GNRALATKDM RKSQERSLSY 120

SDESRLSNLL RRITREDDRD RRLATVKQLK EFIQQPENKQ VLVKQLDNIL TAIHDVLNES 180

SKLLQELRQE GACCLGLLCA SLSYEAEKIF KWIFSKFSSS TKDEVKLLYL CATFKALETV 240

GEKKAFSSVM QLVMTSLQSI LENVDTPELL CKCVKCILLV ARCYPHIFST NFRDTVDILV 300

GWHIDHTQKP SLTQQVSGWL QSLEPFWVAD LAFSTTLLGQ FLEDMEAYAE DLSHVASGES 360

VDEDIPPPSV SLPKLAALLR VFSTVVRSIG ERFSPIRGHP ITEAYVTDVL YRVMRCVTTA 420

NQVFFSEAVL TAANECVGVL LGSLDPSMTI HCDMVITYGL DQLENCQTCG TDYIISVLNL 480

LTLIVEQINT KLPSSFVEKL FIPASKLLLL RYHKEKEVVA VAHAVYQAVL SLKNIPVLET 540

AYKLILGEMT CALNNLLHNL QLPEACSEIQ HDAFKNHVFN VDNAKFVVIF DLSALTTIGN 600

AKNSLIGMWA LSPTVFALLS KNLMIVHGDL AVHFPAIQYA VLYTLYSHCT RHDHFISSSL 660

SSSSPSLFDG AVISTVTTAT KKHFSIILNL LGILLKKDNL NQDTRKLLMT WALEVAVLMK 720

KSETYAPLFS LPSFHKFCKG LLANTLLEDV NICLQACSSL HALSSSLPDD LLQRCVDVCR 780

VQLVHSGTRI RQAFGKLLKS IPLDVVLSNS NHTEIQEISL AIRSHMSKTP SNTFHPQDFS 840

DVISFILYGN SHRTGKDNWL ERLFYSCQRL DKRDQSTIPR NLLKTDAVLW QWAIWEAAQF 900

TVLSKLRTPL GRAQDTFQTI EGIIRSLAAH TLNPDQDVSQ WTTADNDEGH SSNQLRLVLL 960

LQYLENLEKL MYNAYEGCAN ALTSPPKVIR TFFYTNRQTC QDWLTRIRLS IMRVGLLAGQ 1020

PAVTVRHGFD LLTEMKTNSI SQGNELEVII MMVVEALCEL HCPEAIQGLA VWSSAVVGKS 1080

LVWINSVAQQ AEGRFEKATV EYQEHLCAMT GVDCCITGFD KSILKLANMN TNNTSPKHSL 1140

NGDARKTVLA KPSDSSPEVI NYLGNKACEC YISLADWAAV QEWQNAVHDL KKSTSSTSLN 1200

LKADFNYIKS LSSFESGEFL ECTEQLELLP GENINLLASG SKEKIDMKKL LPNMLSPDPR 1260

ELQKSIEVQL LRSSVCLATA VSHIEQEQKW QSITENVVKY LKQTSRIAIG PLRLSTLTVS 1320

QSLPVLSTLQ LYCSSALENT VSNRLSTEDC LIPLYSEALR SCKQHDVRPW MQALRYTVYQ 1380

SQLVEKIKEQ TVPIRSHLME LGLTAAKFAR KRGNVALATR LLAQCSEVRL GKTTTAQDLV 1440

QYFKKLSTQG QIDEKWGPEL DIEKTKLLYT AGQSTHAMEM LSSCAISFCK SAKAEYAVAK 1500

SILTLAKWIQ AEWKEISGQL KQVYRAQQQQ NTTGLSTLSK NIHTLIELPS VNTTEEEYPR 1560

IESESTVNIG VGEPDFILGQ LYHLSSVQAP EVAKSWAALA SWAYRWGRKV VDNASQGEGV 1620

RLLPREKSEV QNLLPDNITE EDREKIYGIL GQAVCRPAGI QDEDITLQIT ESEDNEEDDM 1680

VDVIWRQLLT SCPWLSDLDE NATEGLIKVW RKIVDRIFSL YKLSCSAYFT FLKLNAGQVT 1740

LDEDDPRLHL SIRSEQSTDD VIVMATLRLL RLLVKHAGEL RQYLEHGLET TPTAPWRGII 1800

PQLFSRLNHP EVYVRQSICN LLCRVAQDSP HLILYPAIVG TISLSSESQT SGNKLPSAIP 1860

TLLGNIQGEE LLGAECEGGS PPASQDSNKD EPKNGLNEDQ AMMQDCYSKI VDKLSSANPT 1920

MVLQVQMLVA ELRRVTVLWD ELWLGVLLQQ HMYVLRRIQQ LEDEVKRVQN NNTLRKEEKI 1980

AIMREKHTAL MKPIVFALEH VRSITAAPAE TPHEKWFQDN YGEAIENALE KLKNPLNPAK 2040

PGSSWIPFKE VMLSLQQRAQ KRASYILRLE EISPWLAAMT NTEIALPGEV SARDTVTIHS 2100

VGGTITILPT KTKPKKLLFL GSDGKNYPYL FKGLEDLHLD ERIMQFLSIV NTMFATINRQ 2160

ETPRFHARHY SVTPLGTRSG LIQWVDGATP LFGLYKRWQQ REAALQAQKA QDSYQTPQNP 2220

GIVPRPSELY YSKIGPALKA VGLSLDVSRR DWPLNVMKAV LEELMEATPP NLLAKELWSS 2280

CTTPDEWWRV TQSYARSTAV MSMVGYIIGL GDRHLDNVLI DMTTGEVVHI DYNVCFEKGK 2340

SLRVPEKVPF RMTHNIETAL GVTGVEGVFR LSCEQVLQIM RRGRETLLTL LEAFVYDPLV 2400

DWTAGGEAGF AGAVYGGGGQ QAENKQSKRE MERDITRSLF SSRVAEIKVN WFKNRDEMLI 2460

VLPKLDGSLE EYLSLQEQLT DVEKLQGKLV EEIDFLEGAE GVDHPSHTLQ HRYSEHTQLQ 2520

TQQRTVQEAI QVKLNEFEQW ITHYQAAFNN LEATQLASLL QEISTQMDLG PPSYVPATTF 2580

LQNAGQAHLI SQCEQLEGEV GAFLQQRRSV LRGCLEQLHN YATVALQYPK TIFQKHRIEQ 2640

WKTWMEELIR NTTIERCQEL YRKYELQYAP QPPPTVCQFI TATEMTLQRY AADINNRLIR 2700

QVERLKQEAV TVLVCEEQLK EIERCIKVFL HENGEEGSWS LASVIISALC ALTRRNLMME 2760

GAASSAGEQL VDLTSRDGAW FLEELCSMSG NVTCLVQLLK QCHLVPQDLD IPNPLEASEA 2820

VHLANGVYTS LQELNSNFRQ IIFPEALRCL MKGEYTLESM LHELDNLIEQ TTDGVPLQTL 2880

VDSLQAYLRN AAMGLEEETH SHYIDVARLH SQYGELIQPR NGSVDETPKM SAGQMLLVAF 2940

DGMFAQVETA FGLLIEKLNK MEVPVSWRKI DIIREARSTQ INFFDDDNHR QVLEEIFFLK 3000

RLQTIKEFFR LCGTFSKTLS GSSSLEDQSP VNGPVQIVNV KTLFRNSCFS EDQMAKPIKA 3060

FTADFVRQLL IGLPNQALGL TLCSFISALG VDIIAQVEAK DFGAESKVSV DDLCKKAVEH 3120

NIQIGKFSQL VMNRATVLAS SYDTAWKKHD LVRRLETSIS SFKTSLQRVQ LQIAMFQWQH 3180

EDLLITRPQA MSVTPPPRSA ILTNMKKKLH TLSQIETSIA AVQEKLAALE ASIEQRLKWA 3240

GGANPALAPV LQDFEATIAE RRNLVLKESQ RANQVTFLCS NIIHFESLRT RTAEALNLDA 3300

ALFELIKRCQ QMCSFASQFN SSVSELELRL LQRVGSGLEP PIGSPEWLVS AHKQLTQDMS 3360

TQRAVQTEKE QQIESVCEAI QNLVDSIKTV LTGHNRQLGD VKHLLKAMAK DEEAALADGE 3420

DVPYENSVRQ FLGEYKSWQD NIQTVLFTLV QAMGQVRSQE HVEMLQEITP TLKELKTQSQ 3480

SIYNNLVSFA SPLVTDATNE CSSPTSSATY QPTFAAAVRS NTGQKTQPEV MSQNARKLIQ 3540

KNLATSADTP PSTVPGTGKS VACSPKKAVR DPKTGKAVQE RNSYAVSVWK RVKAKLEGRD 3600

VDPNRRMSVA EQVDYVIKEA TNLDNLAQLY EGWTAWV 3637

Nucleotide Sequence
(FASTA)

ATGTTTTTCT CTGATTTTTG CAGAACTGAT AGTGCACCAG CCGACCAGGA TCATTTAAAA 60

TATTCTTCGT CTAGAGATCG GGGCAGTTCT GCCTCTTATG GATTACAACC TTCAAATTCA 120

GTTGTGGTGT CTCGTCAACG GCACGATGAT ATCAGAGTCC ACACCGACAT ACAGAATGAA 180

GAAAAGGGTG GCTACAATGT CAATGGAGGA GCTGGGGAAA ATACTTATGG TCGGAAGTCG 240

TTGGGGCAAG AGCTGAGGGT TAACAATGTG ACCAACCCTG ATTTCACCAG TGTTCAGCAT 300

GGAAATCGTG CTTTAGCCAC AAAAGACATG AGGAAATCAC AGGAGCGATC GTTGTCTTAC 360

TCTGACGAGT CTCGACTGTC AAACCTTCTT CGGAGGATTA CCCGGGAAGA CGACAGAGAC 420

CGAAGACTGG CTACTGTGAA GCAATTGAAA GAATTCATTC AGCAACCAGA AAATAAGCAG 480

GTCTTAGTTA AACAACTGGA TAATATCCTG ACCGCTATAC ATGATGTGCT TAATGAAAGT 540

AGCAAATTGC TTCAGGAATT GAGGCAGGAG GGAGCTTGCT GTCTTGGCCT TCTTTGTGCT 600

TCTTTGAGTT ATGAGGCCGA GAAGATCTTC AAATGGATTT TTAGCAAATT TAGCTCGTCC 660

ACAAAAGATG AAGTTAAACT GCTTTACTTA TGTGCCACCT TCAAAGCACT AGAGACTGTA 720

GGAGAAAAGA AAGCCTTTTC ATCTGTAATG CAGCTTGTAA TGACCAGCCT GCAGTCCATT 780

CTAGAAAATG TGGATACACC AGAATTGCTA TGCAAATGTG TGAAGTGCAT TCTTCTGGTG 840

GCCCGATGTT ACCCTCATAT TTTCAGCACT AATTTTAGGG ATACGGTTGA CATATTGGTT 900

GGGTGGCATA TAGATCACAC TCAGAAACCT TCCTTGACAC AGCAAGTGTC TGGATGGCTG 960

CAGAGTCTGG AGCCCTTTTG GGTAGCCGAT CTTGCATTTT CCACCACCCT TCTCGGTCAG 1020

TTTCTGGAAG ATATGGAGGC TTATGCTGAA GATCTCAGTC ATGTGGCATC TGGGGAATCG 1080

GTCGATGAAG ACATTCCTCC TCCATCAGTG TCCTTACCGA AGTTGGCGGC TCTTCTCCGG 1140

GTTTTCAGTA CTGTGGTGCG GAGTATTGGG GAGCGCTTCA GTCCAATTAG AGGACATCCA 1200

ATTACCGAGG CTTATGTAAC AGATGTTTTG TACAGAGTAA TGAGATGTGT GACAACAGCA 1260

AACCAAGTAT TTTTTTCTGA AGCTGTATTG ACAGCTGCCA ATGAATGTGT CGGTGTATTG 1320

CTTGGTAGCC TAGATCCTAG TATGACTATT CATTGTGACA TGGTCATCAC CTATGGACTA 1380

GACCAACTGG AGAATTGCCA GACTTGTGGT ACAGATTATA TCATCTCGGT CTTAAATTTA 1440

CTGACGTTGA TTGTTGAGCA GATCAATACA AAGCTGCCAT CGTCATTCGT CGAAAAACTG 1500

TTTATACCAG CGTCTAAACT ACTGCTTCTG CGCTATCATA AAGAAAAAGA GGTTGTTGCA 1560

GTAGCTCATG CTGTATATCA AGCCGTTCTT AGCCTGAAGA ACATTCCCGT CTTGGAGACC 1620

GCCTATAAGT TAATTTTAGG AGAAATGACT TGTGCACTGA ATAATCTCCT GCATAACCTT 1680

CAACTTCCTG AGGCCTGTTC CGAAATCCAA CACGATGCTT TTAAGAATCA CGTTTTCAAT 1740

GTGGACAATG CCAAATTTGT AGTTATATTT GACCTCAGTG CCCTGACCAC GATTGGAAAT 1800

GCGAAAAACT CATTAATTGG GATGTGGGCA CTCTCGCCAA CCGTTTTTGC ACTTCTGAGC 1860

AAGAATCTGA TGATAGTGCA TGGAGATCTC GCCGTTCACT TCCCAGCTAT TCAGTATGCC 1920

GTTCTCTACA CTTTGTATTC ACATTGTACC AGACATGATC ACTTCATTTC TAGCAGTCTT 1980

AGCTCCTCTT CTCCTTCTCT CTTTGATGGA GCAGTTATCA GCACTGTCAC CACAGCTACA 2040

AAGAAGCATT TCTCAATCAT ATTAAACCTC CTGGGAATAT TACTGAAGAA AGATAATCTT 2100

AATCAGGATA CCAGGAAACT ACTAATGACC TGGGCTTTGG AAGTTGCTGT TCTAATGAAA 2160

AAGTCTGAAA CATATGCACC TTTGTTCTCT CTTCCGTCGT TCCATAAATT TTGCAAAGGA 2220

CTTCTAGCAA ACACTCTTCT TGAAGATGTG AATATCTGCC TTCAAGCATG TAGTAGTCTG 2280

CATGCCTTGT CATCTTCCCT GCCAGATGAC CTTTTACAAA GGTGTGTTGA TGTGTGCCGC 2340

GTTCAGCTGG TCCATAGTGG AACTCGGATT CGACAAGCCT TTGGAAAGCT GTTGAAGTCT 2400

ATTCCGTTAG ATGTTGTCTT GAGCAATAGC AACCACACAG AGATTCAAGA AATTTCCTTA 2460

GCTATAAGGA GTCACATGAG CAAAACTCCA AGTAATACTT TCCATCCACA AGATTTCTCT 2520

GACGTGATAA GTTTTATTTT GTATGGAAAC TCTCATAGAA CCGGGAAGGA CAATTGGTTA 2580

GAAAGATTGT TCTACAGCTG TCAGAGATTG GATAAGCGTG ATCAGTCAAC CATTCCACGC 2640

AATCTACTCA AAACAGATGC CGTCCTCTGG CAGTGGGCTA TTTGGGAAGC TGCTCAGTTC 2700

ACTGTTCTCT CTAAACTAAG AACCCCGCTG GGCAGAGCTC AAGATACCTT CCAGACAATC 2760

GAAGGTATCA TTAGAAGTCT TGCCGCTCAT ACATTAAACC CCGATCAAGA TGTTAGCCAG 2820

TGGACCACTG CGGACAATGA TGAAGGACAT AGCAGCAACC AACTCAGACT TGTTCTTCTA 2880

CTGCAGTACT TGGAAAATTT GGAAAAACTA ATGTATAATG CATATGAAGG TTGTGCTAAT 2940

GCACTGACTT CCCCTCCTAA GGTTATCAGG ACATTTTTCT ATACCAATCG CCAGACATGT 3000

CAGGACTGGT TAACTCGGAT TAGACTTTCC ATCATGAGAG TTGGATTGTT GGCCGGTCAG 3060

CCCGCTGTGA CAGTAAGACA CGGTTTTGAT TTGCTCACCG AAATGAAGAC CAATAGTATC 3120

TCTCAGGGAA ATGAGCTAGA AGTGATTATT ATGATGGTCG TAGAAGCACT TTGTGAGCTT 3180

CACTGTCCTG AAGCTATACA GGGATTAGCT GTCTGGTCTT CAGCAGTGGT TGGAAAGAGT 3240

CTCGTCTGGA TTAATTCAGT GGCACAGCAA GCCGAAGGGC GGTTTGAAAA GGCAACTGTT 3300

GAATACCAGG AGCACTTGTG TGCTATGACA GGGGTAGATT GCTGCATAAC TGGGTTTGAT 3360

AAATCCATTC TGAAGTTGGC TAACATGAAT ACTAACAATA CCAGCCCCAA ACATTCTCTC 3420

AATGGTGACG CTAGGAAAAC TGTTCTGGCC AAACCAAGTG ATTCTTCTCC TGAGGTTATT 3480

AATTACTTGG GTAACAAAGC ATGTGAGTGC TACATCTCTC TTGCTGATTG GGCTGCTGTG 3540

CAGGAATGGC AGAATGCTGT CCATGACTTG AAAAAGAGCA CAAGTAGTAC TTCCCTCAAT 3600

TTAAAAGCTG ACTTTAACTA CATAAAATCA CTGAGCAGCT TTGAATCTGG CGAATTTCTC 3660

GAATGTACAG AACAACTAGA ATTGCTGCCA GGAGAAAACA TTAACTTACT TGCCAGCGGG 3720

TCAAAGGAAA AAATAGATAT GAAAAAGCTA CTTCCAAACA TGTTAAGCCC AGATCCACGG 3780

GAACTTCAGA AATCCATTGA AGTTCAGTTG CTGAGAAGTT CCGTTTGTTT GGCTACCGCT 3840

GTAAGCCACA TAGAGCAGGA ACAAAAGTGG CAATCTATAA CTGAAAACGT TGTAAAATAT 3900

TTGAAGCAAA CATCAAGAAT AGCTATTGGA CCACTGAGAC TTTCCACTTT AACTGTTTCA 3960

CAGTCCTTAC CAGTTCTAAG TACCCTACAG CTGTATTGTT CTTCTGCTTT GGAGAACACC 4020

GTGTCAAACA GGCTTTCGAC AGAGGACTGC TTAATCCCAC TCTATAGTGA AGCTTTACGT 4080

TCGTGTAAAC AGCATGATGT AAGGCCCTGG ATGCAGGCTT TGAGGTATAC AGTATACCAG 4140

AGTCAGTTGG TGGAAAAAAT CAAAGAACAA ACGGTTCCAA TTAGAAGTCA CCTCATGGAA 4200

TTGGGTTTAA CAGCTGCGAA ATTTGCTCGT AAACGTGGAA ACGTTGCCCT GGCAACCAGA 4260

TTGCTCGCTC AATGTAGTGA AGTGCGGTTG GGAAAGACGA CCACTGCTCA AGATTTAGTC 4320

CAGTATTTTA AAAAACTGTC AACACAAGGT CAAATAGATG AAAAATGGGG ACCTGAACTG 4380

GATATTGAGA AAACGAAATT GTTATACACA GCAGGTCAGT CAACCCATGC GATGGAAATG 4440

CTGAGTTCTT GCGCCATATC CTTCTGCAAG TCTGCCAAAG CTGAATACGC AGTAGCCAAA 4500

TCGATTCTTA CACTTGCTAA ATGGATCCAA GCTGAATGGA AAGAAATTTC AGGACAGTTG 4560

AAACAGGTGT ACAGAGCCCA ACAGCAGCAG AACACCACGG GCCTGTCTAC ATTATCTAAA 4620

AACATACACA CTTTGATCGA ACTGCCGTCT GTCAACACCA CAGAAGAGGA GTATCCCCGC 4680

ATCGAGAGTG AATCAACAGT CAACATTGGA GTTGGGGAAC CGGACTTCAT CCTGGGCCAG 4740

TTGTATCACC TGTCTTCAGT GCAGGCACCC GAAGTGGCCA AATCTTGGGC AGCGCTGGCA 4800

AGTTGGGCTT ACAGATGGGG AAGAAAGGTG GTGGATAACG CCAGTCAGGG AGAAGGTGTT 4860

CGACTACTGC CAAGAGAGAA ATCTGAGGTT CAAAATCTGC TTCCAGACAA CATAACAGAG 4920

GAGGATCGAG AGAAGATCTA CGGCATCCTT GGGCAGGCGG TGTGTCGGCC AGCCGGAATT 4980

CAGGATGAAG ATATAACACT GCAGATAACA GAGAGTGAAG ACAATGAGGA AGATGACATG 5040

GTGGATGTGA TCTGGCGTCA GTTATTGACG AGTTGCCCGT GGCTTTCCGA TCTTGATGAA 5100

AATGCCACAG AAGGCCTAAT TAAAGTGTGG AGAAAAATTG TAGATAGGAT ATTCAGTCTC 5160

TACAAACTGT CCTGCAGTGC CTATTTTACT TTCCTTAAAC TCAATGCTGG CCAGGTTACT 5220

CTAGATGAAG ATGACCCAAG GCTGCACTTG AGCATTAGGT CTGAACAAAG CACTGACGAT 5280

GTTATTGTAA TGGCAACGTT AAGACTGTTG AGATTGCTGG TCAAACACGC TGGAGAGCTA 5340

AGGCAGTATC TGGAGCACGG CCTAGAAACC ACCCCCACTG CTCCTTGGAG AGGTATCATT 5400

CCACAGCTCT TCTCCCGTCT AAATCATCCC GAAGTGTACG TCCGCCAAAG TATTTGTAAT 5460

CTACTCTGTC GAGTGGCACA AGATTCTCCT CATCTCATAT TATATCCTGC AATTGTGGGA 5520

ACTATTTCAC TGAGTAGTGA ATCGCAGACA TCAGGCAATA AGTTGCCTTC AGCCATCCCC 5580

ACTTTGCTGG GCAATATTCA AGGCGAAGAA TTACTCGGAG CGGAATGTGA AGGGGGAAGT 5640

CCTCCAGCTT CTCAAGACAG CAATAAAGAT GAACCCAAGA ATGGCTTAAA TGAAGATCAA 5700

GCGATGATGC AGGATTGCTA CAGCAAAATT GTTGATAAAT TGTCTTCTGC CAACCCAACA 5760

ATGGTCTTAC AGGTTCAAAT GCTGGTGGCC GAGTTGCGCA GGGTGACCGT TCTTTGGGAT 5820

GAGCTCTGGC TGGGAGTTCT TCTACAACAA CATATGTATG TTCTGAGGCG CATTCAACAG 5880

TTGGAGGACG AAGTAAAGAG AGTCCAGAAT AACAATACGT TACGCAAAGA AGAGAAGATT 5940

GCAATAATGC GAGAAAAGCA CACAGCTCTG ATGAAGCCCA TCGTATTTGC TTTGGAACAT 6000

GTACGGAGCA TCACTGCCGC TCCTGCCGAA ACACCTCATG AGAAGTGGTT CCAAGACAAC 6060

TATGGTGAGG CAATTGAAAA TGCCCTGGAA AAACTCAAGA ACCCATTAAA TCCTGCAAAA 6120

CCCGGAAGCA GTTGGATCCC ATTTAAAGAG GTGATGCTAA GTTTGCAGCA GAGAGCACAG 6180

AAACGTGCTA GTTATATCTT GCGCCTTGAA GAAATCAGCC CCTGGTTGGC TGCCATGACT 6240

AATACTGAAA TTGCCCTTCC TGGAGAAGTA TCAGCCAGAG ATACCGTGAC GATCCACAGC 6300

GTGGGCGGAA CCATCACAAT CCTACCTACT AAAACCAAAC CCAAAAAACT GCTCTTTCTG 6360

GGTTCAGACG GGAAAAACTA CCCCTATCTC TTTAAAGGAC TGGAAGATCT GCACCTGGAT 6420

GAGAGAATCA TGCAGTTTCT ATCTATCGTT AATACCATGT TCGCTACCAT CAATCGCCAA 6480

GAGACGCCCC GTTTCCATGC CAGGCACTAT TCGGTGACCC CGCTGGGGAC GAGGTCGGGC 6540

CTGATTCAGT GGGTAGATGG AGCCACTCCC TTATTTGGCC TTTACAAGCG ATGGCAACAG 6600

CGAGAAGCTG CTTTACAAGC GCAAAAGGCC CAGGATTCTT ACCAGACTCC TCAAAATCCT 6660

GGAATAGTAC CTCGGCCCAG CGAGCTTTAT TACAGTAAAA TCGGGCCCGC CCTGAAAGCG 6720

GTCGGACTCA GTCTCGACGT GTCCCGGCGA GACTGGCCTC TCAACGTGAT GAAGGCTGTG 6780

TTGGAAGAAC TGATGGAAGC CACCCCTCCA AACCTTCTGG CCAAGGAGCT TTGGTCTTCT 6840

TGTACCACAC CTGACGAATG GTGGAGAGTT ACCCAGTCTT ACGCAAGATC CACCGCGGTC 6900

ATGTCAATGG TTGGATACAT AATCGGCCTT GGAGATAGAC ATCTGGATAA CGTTCTTATA 6960

GACATGACTA CAGGAGAAGT TGTTCACATA GATTACAATG TTTGTTTTGA AAAAGGTAAA 7020

AGTCTGAGAG TGCCGGAGAA AGTTCCTTTC AGGATGACTC ACAACATCGA AACAGCTCTC 7080

GGTGTAACTG GAGTTGAGGG AGTTTTCAGG CTTTCTTGTG AACAGGTTCT CCAAATTATG 7140

CGGCGTGGAA GAGAGACCCT GCTCACGTTG CTGGAAGCCT TTGTGTACGA TCCTCTTGTG 7200

GACTGGACAG CCGGAGGGGA AGCAGGATTT GCAGGAGCTG TCTATGGCGG AGGCGGCCAG 7260

CAGGCAGAGA ACAAGCAAAG TAAAAGGGAG ATGGAAAGGG ACATCACCCG CAGCCTCTTT 7320

TCTTCCCGAG TAGCTGAAAT CAAGGTGAAC TGGTTTAAAA ACAGAGATGA GATGTTGATT 7380

GTGCTTCCAA AGCTAGATGG AAGCTTAGAA GAATACCTGA GCCTACAAGA GCAATTGACA 7440

GATGTTGAAA AACTGCAAGG CAAACTCGTT GAGGAGATTG ACTTTCTAGA AGGAGCCGAA 7500

GGAGTAGATC ATCCCTCGCA CACTCTGCAG CACAGGTATT CCGAACACAC CCAACTGCAG 7560

ACTCAGCAGA GAACCGTTCA AGAAGCCATC CAGGTGAAGT TGAATGAATT TGAGCAGTGG 7620

ATAACACATT ACCAAGCTGC GTTTAACAAT TTAGAAGCCA CCCAGCTGGC CAGTCTGCTT 7680

CAGGAGATTA GCACCCAAAT GGACCTGGGT CCTCCAAGCT ACGTGCCTGC AACCACCTTT 7740

CTGCAGAACG CTGGCCAAGC CCACTTGATC AGTCAGTGCG AGCAGCTGGA GGGCGAGGTT 7800

GGAGCTTTCC TTCAGCAGAG GCGCTCCGTC CTGCGAGGCT GTCTCGAGCA GCTGCATAAC 7860

TACGCGACCG TAGCCCTTCA GTACCCGAAA ACCATATTCC AGAAACACCG AATCGAGCAG 7920

TGGAAGACCT GGATGGAAGA ACTTATACGC AATACGACCA TCGAGAGATG TCAGGAGTTG 7980

TACCGGAAAT ATGAACTCCA GTATGCCCCC CAGCCACCAC CCACGGTGTG TCAGTTCATA 8040

ACTGCCACTG AAATGACTCT TCAGCGCTAC GCGGCAGACA TAAATAATAG GCTTATCAGA 8100

CAAGTGGAGC GCCTGAAACA AGAAGCAGTG ACCGTGCTGG TCTGCGAGGA GCAGTTAAAA 8160

GAAATTGAAC GGTGTATTAA GGTTTTTCTT CATGAAAACG GAGAGGAGGG GTCCTGGAGC 8220

CTGGCGAGCG TTATCATCTC TGCACTCTGT GCACTTACAA GGCGCAACTT AATGATGGAA 8280

GGTGCCGCTT CTAGTGCTGG CGAGCAGCTG GTCGATCTGA CTTCCCGAGA TGGGGCCTGG 8340

TTCTTGGAGG AGCTGTGCAG CATGAGTGGA AATGTAACCT GCCTTGTACA GTTACTGAAG 8400

CAGTGTCACC TGGTCCCTCA GGATTTAGAT ATTCCCAATC CCCTCGAAGC TTCGGAGGCA 8460

GTTCACTTAG CTAATGGAGT CTACACCTCG CTTCAGGAAT TGAACTCCAA CTTCCGGCAG 8520

ATCATCTTTC CGGAAGCTCT GCGATGTTTA ATGAAAGGGG AATACACTTT AGAAAGCATG 8580

CTGCACGAAC TGGACAACCT CATTGAACAG ACAACTGATG GAGTTCCGTT GCAAACCCTG 8640

GTTGACTCTC TTCAGGCCTA TTTAAGAAAT GCAGCTATGG GCCTGGAAGA AGAGACACAT 8700

TCTCACTATA TTGATGTTGC CAGACTCCAT TCTCAGTATG GCGAATTGAT TCAACCAAGG 8760

AATGGTTCAG TTGATGAAAC ACCAAAAATG TCCGCCGGTC AAATGCTTTT GGTTGCGTTC 8820

GATGGAATGT TCGCCCAAGT GGAAACCGCT TTTGGCTTGT TAATTGAAAA GTTAAACAAG 8880

ATGGAAGTCC CCGTATCGTG GCGAAAGATA GACATCATAA GAGAAGCCAG AAGCACCCAG 8940

ATTAATTTCT TTGACGACGA TAATCACCGA CAGGTTCTGG AGGAGATTTT CTTTCTCAAA 9000

AGACTGCAGA CCATCAAAGA ATTCTTTAGA CTCTGTGGTA CTTTTTCTAA AACGCTGTCA 9060

GGATCGAGTT CGCTCGAAGA TCAGAGCCCG GTGAATGGAC CCGTTCAAAT TGTTAATGTG 9120

AAAACGCTTT TCAGAAACTC TTGTTTTAGT GAAGATCAGA TGGCCAAACC CATAAAGGCG 9180

TTCACAGCTG ACTTCGTGAG GCAGCTCTTA ATTGGCCTGC CTAATCAAGC CTTGGGGCTA 9240

ACCCTTTGCA GTTTCATCAG CGCGCTGGGC GTCGACATCA TCGCCCAGGT CGAGGCAAAG 9300

GACTTTGGGG CAGAGAGCAA GGTTTCGGTG GACGATCTGT GTAAGAAAGC CGTGGAGCAC 9360

AACATCCAGA TTGGAAAGTT CTCCCAGCTG GTCATGAACC GAGCCACGGT CCTGGCCAGT 9420

TCCTACGACA CTGCTTGGAA GAAGCACGAT TTGGTGCGCA GGCTAGAAAC CAGTATTTCC 9480

TCTTTCAAGA CCAGCCTGCA GAGAGTGCAG CTCCAGATCG CCATGTTTCA GTGGCAGCAC 9540

GAAGATCTCC TAATCACCCG ACCACAAGCC ATGTCTGTGA CTCCTCCACC TCGCTCTGCT 9600

ATTCTAACAA ATATGAAAAA GAAGCTGCAT ACCCTGAGCC AGATCGAAAC GTCCATTGCA 9660

GCGGTTCAGG AGAAACTAGC AGCCCTCGAA GCAAGCATCG AACAACGTTT GAAGTGGGCA 9720

GGAGGGGCCA ATCCCGCATT GGCTCCAGTC CTACAAGATT TTGAGGCAAC AATAGCGGAA 9780

AGAAGGAATC TCGTTCTGAA AGAAAGCCAA CGAGCAAATC AGGTCACTTT CCTCTGCAGC 9840

AATATCATTC ATTTTGAAAG CCTACGAACG CGAACTGCCG AAGCTCTAAA TCTCGATGCT 9900

GCCTTGTTTG AACTCATCAA GCGCTGTCAA CAGATGTGTT CGTTTGCCTC ACAGTTTAAC 9960

AGCTCGGTTT CTGAACTGGA ACTGCGTTTA CTGCAAAGAG TGGGTTCCGG TCTCGAACCT 10020

CCCATTGGCA GCCCTGAATG GCTTGTTTCT GCACACAAAC AACTGACCCA GGATATGTCT 10080

ACTCAGAGGG CGGTTCAAAC AGAAAAAGAA CAGCAAATCG AATCAGTCTG TGAAGCAATT 10140

CAGAACCTTG TGGATAGTAT TAAGACAGTG CTTACCGGTC ACAACAGGCA ACTTGGAGAT 10200

GTTAAACATC TATTGAAAGC AATGGCCAAG GATGAAGAGG CTGCTTTGGC AGATGGTGAA 10260

GATGTTCCCT ATGAGAACAG TGTTAGACAA TTCTTGGGTG AATATAAGTC ATGGCAAGAC 10320

AATATTCAAA CGGTATTGTT TACATTAGTT CAGGCTATGG GGCAGGTTCG CAGCCAAGAG 10380

CATGTGGAGA TGCTGCAGGA GATAACTCCC ACCTTGAAAG AGCTGAAAAC ACAAAGCCAG 10440

AGTATCTACA ATAATCTAGT GAGTTTTGCA TCACCCTTAG TCACAGATGC AACAAATGAG 10500

TGTTCCAGCC CAACATCATC TGCTACGTAT CAGCCAACCT TTGCTGCAGC GGTCCGCAGT 10560

AACACTGGCC AGAAGACTCA GCCTGAAGTT ATGTCGCAGA ATGCAAGGAA GCTGATTCAG 10620

AAAAATCTTG CAACATCAGC AGATACCCCA CCAAGCACAG TTCCAGGAAC TGGCAAGAGT 10680

GTGGCCTGTA GTCCTAAAAA AGCAGTCAGG GATCCAAAAA CTGGAAAAGC TGTGCAAGAA 10740

AGGAACTCCT ATGCAGTGAG TGTGTGGAAG CGAGTCAAAG CCAAGTTAGA GGGCCGAGAT 10800

GTGGATCCGA ACAGGAGGAT GTCTGTTGCT GAACAGGTGG ACTATGTGAT TAAGGAAGCA 10860

ACTAATCTAG ATAACTTGGC TCAGCTGTAT GAAGGTTGGA CGGCCTGGGT ATGA 10914

Domain Profile

S: 3     gfderveilaskqkpkklllrGsdgkeypyLvkgkeDlrqdervlqlfslvNtlLakdke  62

         ++  +++il++k+kpkkll++Gsdgk ypyL+kg+eDl+ der++q++s+vNt++a+ ++

Q: 2100  SVGGTITILPTKTKPKKLLFLGSDGKNYPYLFKGLEDLHLDERIMQFLSIVNTMFATINR  2159

         566789******************************************************

S: 63    tsrrkLkirtykVvplstrsgliewventvsLkellkklvekkavlldqpi..syrykdl  120

         ++++++++r+y+V+pl+trsgli+wv+++++L+ l+k++++++a+l++q++  sy+++++

Q: 2160  QETPRFHARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAALQAQKAqdSYQTPQN  2219

         **************************************************999*******

S: 121   stvqar.........kpklkhlkls.........levfkevlenlv...pkdllkkllle  159

         + +++r         +p+lk++ ls         l+v+k+vle+l+   p++ll+k+l++

Q: 2220  PGIVPRpselyyskiGPALKAVGLSldvsrrdwpLNVMKAVLEELMeatPPNLLAKELWS  2279

         ***************999999999999****************999999***********

S: 160   kfpspeewfelrkaytrslAvislvgyiLgLgdrhlenllidqetgevvhidfgvafeka  219

         ++++p+ew++++++y+rs+Av+s+vgyi+gLgdrhl+n+lid++tgevvhid++v+fek+

Q: 2280  SCTTPDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKG  2339

         ************************************************************

S: 220   ktqlkvpekvPFRLTrnivnalgvtgveGvfrasceavlrvlreskeklltiLevflydp  279

         k+ l+vpekvPFR+T+ni++algvtgveGvfr sce+vl+++r+ +e+llt+Le+f+ydp

Q: 2340  KS-LRVPEKVPFRMTHNIETALGVTGVEGVFRLSCEQVLQIMRRGRETLLTLLEAFVYDP  2398

         **.*********************************************************

S: 280   lvdwkk...............k  286

         lvdw+                +

Q: 2399  LVDWTAggeagfagavyggggQ  2420

         *****97777766666554432

Domain Sequence
(FASTA)

SVGGTITILP TKTKPKKLLF LGSDGKNYPY LFKGLEDLHL DERIMQFLSI VNTMFATINR 60

QETPRFHARH YSVTPLGTRS GLIQWVDGAT PLFGLYKRWQ QREAALQAQK AQDSYQTPQN 120

PGIVPRPSEL YYSKIGPALK AVGLSLDVSR RDWPLNVMKA VLEELMEATP PNLLAKELWS 180

SCTTPDEWWR VTQSYARSTA VMSMVGYIIG LGDRHLDNVL IDMTTGEVVH IDYNVCFEKG 240

KSLRVPEKVP FRMTHNIETA LGVTGVEGVF RLSCEQVLQI MRRGRETLLT LLEAFVYDPL 300

VDWTAGGEAG FAGAVYGGGG Q 321

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0016301	; F:kinase activity
GO:0016773	; F:phosphotransferase activity, alcohol group as acceptor

KEGG

InterPros

IPR011989	; ARM-like.
IPR016024	; ARM-type_fold.
IPR003152	; FATC.
IPR011009	; Kinase-like_dom.
IPR000403	; PI3/4_kinase_cat_dom.
IPR018936	; PI3/4_kinase_CS.
IPR014009	; PIK_FAT.

Pfam

PF02260	; FATC; 1.
PF00454	; PI3_PI4_kinase; 1.

SMARTs

SM00146

; PI3Kc; 1.

Prosites

PS51189	; FAT; 1.
PS51190	; FATC; 1.
PS00916	; PI3_4_KINASE_2; 1.
PS50290	; PI3_4_KINASE_3; 1.

Prints

Created Date

20-Feb-2013