EKS-ORA-00256

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORA-00256

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/BUB	351.6	2.6E-105	822	1090	269

Status

Unreviewed

Ensembl Protein

ENSOANP00000019968

UniProt Accession

F7FTL8;

Protein Name

Protein Synonyms/Alias

Gene Name

BUB1

Gene Synonyms/Alias

BUB1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOANG00000012628	ENSOANP00000019968	ENSOANT00000019971

Organism

Ornithorhynchus anatinus

Functional Description

Protein Length

1122

Protein Sequence
(FASTA)

MFETHIQSYK GDDPLDLWER YVQWTEETFP QNNKHLSTLL ERLVKTFLNQ KRYYTDPRFI 60

NCCVKFAEHN SEPHQFYEFI YQQGIGIKSS DLYVAWSQQL EGRGDLKQAG AVLQKGVQNQ 120

SEPTEVLQQQ YRLFQARLSK THFAAQVGAS EPLQNSKILN QIVPPLTGNG DPACLPQSQS 180

SGLSENQSST CDKVPKMQAQ SVEQRTVVIS KSCYSAQPSL SASNSNTEQI CMYCKDKLIH 240

GDSELSFEEL RAQKHEQVKK QKEWVNKDRE YLKRKEADSF EEQLLKQKMN ELRKQLCQVA 300

TVQGGLATLQ AGSQIRPIYT EPSLQRDLSA PFRPATSQTP SNAAEYLKNS IALPTAAETS 360

ASSETPVTEN QPYPVSRETQ PAADSTFATY QEDASKTRFD PEEGREQNLI PSDHHRSISK 420

PGPLEEPSTS PPESFSFREP YKNETGQGLK LQNGKEGKEV NEASSYFGTN ASHATPNTSL 480

GMVQATPSKV QPSPTVHTKE ALGFIMNMFQ IPTHPEVSGE EDNFPCLDEN EEAFEACFKK 540

NTESSGVLGI KSINPATTPA FSIFEDGNKE NNGPPESKNK PGGTRSFGER PASRLALKPN 600

EEAQVAETLD DCTVWGVRCN KTLAPSPNST RDFARAAQFA STPFNGFPVY LRPTLENKEN 660

MIANRAADTH LNSSEEKPLL SSENKKLSPI QEHSPDLQDL PEEMLSNTSL ILKPQGPCGG 720

LLTEEVELGL AACKVTEITL AMEDEPEEAS AEQMGLPEQS PPAESVKSPD FIVENPWDDQ 780

LIHRFLSNLS KPVNSYPNTF EWASNVPAIK LKTQVHVGTA PFYIDCLLGE GAFAHVYQAT 840

VLNMDDPKNN QKVILKVQKP ANPWEFYIGT QLLERLHPNV RHLFIRFYSA HLFHNGSVLV 900

GELYSYGTLL NAINLYKNTP EKTMPQALVM YFALKIMFMI ERLHDCEIIH GDIKPDNFIL 960

GERFLEDDDW TVDSPPHGLT VIDLGQSIDM TLFPKGTAFT GRCETSGFQC VEMLSRKPWN 1020

YQTDYFGVAA TVYCMLFGTY MKVKNEQGVW KAEGIFKRLP HSEMWNDFFH TLLNIPDCHH 1080

LPSLGALREK LKVILQQSYG NKIKSLRKRL VVLLLENKRS RK 1122

Nucleotide Sequence
(FASTA)

ATGTTTGAAA CCCACATACA AAGCTACAAA GGAGATGACC CACTCGATCT CTGGGAGAGA 60

TATGTGCAAT GGACAGAAGA AACCTTTCCT CAGAATAACA AACACTTGTC AACTTTGTTA 120

GAGCGGTTGG TGAAGACATT TTTAAATCAG AAAAGATATT ACACTGACCC AAGATTCATC 180

AACTGCTGTG TAAAATTTGC TGAGCACAAT AGTGAACCAC ATCAGTTCTA TGAGTTTATA 240

TACCAGCAAG GAATTGGCAT CAAGTCATCC GACCTTTACG TAGCCTGGAG TCAGCAGCTT 300

GAAGGCCGAG GTGACCTGAA GCAGGCCGGT GCTGTTTTGC AGAAGGGGGT TCAGAATCAG 360

TCAGAGCCCA CGGAAGTGCT TCAACAACAG TACAGGTTGT TCCAGGCTCG ACTGTCCAAA 420

ACTCATTTTG CAGCTCAAGT TGGCGCCTCA GAACCACTTC AAAATTCTAA GATTTTAAAC 480

CAGATTGTCC CACCTCTCAC AGGGAATGGA GACCCTGCAT GCCTTCCCCA AAGTCAGAGT 540

TCGGGGCTTT CTGAAAATCA GTCATCCACT TGTGATAAAG TACCAAAAAT GCAAGCACAG 600

TCAGTAGAAC AGAGGACCGT CGTCATTTCT AAATCGTGCT ATTCTGCGCA ACCATCTTTA 660

TCGGCGTCCA ATAGCAACAC CGAGCAAATT TGCATGTACT GTAAGGACAA GCTTATTCAT 720

GGAGACTCTG AATTATCTTT TGAAGAACTG AGAGCCCAGA AACACGAACA AGTGAAAAAA 780

CAAAAGGAAT GGGTAAATAA AGACAGAGAG TACTTGAAAC GGAAAGAAGC AGATTCCTTT 840

GAAGAACAAC TCCTGAAACA GAAAATGAAT GAACTCCGTA AGCAGTTGTG TCAAGTGGCA 900

ACGGTGCAGG GTGGATTAGC CACTCTTCAG GCTGGATCTC AGATTCGCCC GATATACACG 960

GAACCCAGTT TGCAGCGAGA CCTGTCGGCA CCTTTTCGAC CAGCCACCAG TCAGACACCA 1020

AGTAACGCAG CAGAATACTT AAAGAACTCC ATAGCTCTAC CCACGGCAGC AGAGACAAGC 1080

GCTTCTTCAG AAACACCGGT GACCGAGAAT CAGCCTTATC CTGTGTCAAG AGAGACCCAG 1140

CCAGCGGCAG ATTCTACATT CGCAACCTAC CAAGAGGACG CTAGCAAGAC TCGGTTCGAC 1200

CCCGAAGAGG GTCGAGAGCA GAACCTGATC CCATCTGACC ACCACAGGAG CATCTCTAAA 1260

CCTGGACCTC TTGAGGAGCC CTCAACCTCT CCTCCTGAGA GCTTCAGCTT TAGAGAGCCG 1320

TATAAGAATG AAACTGGTCA AGGCCTCAAA CTACAAAACG GGAAGGAGGG CAAAGAAGTA 1380

AATGAAGCCT CTTCATATTT TGGGACAAAT GCATCTCATG CCACACCAAA TACATCCCTG 1440

GGAATGGTAC AGGCGACGCC ATCAAAAGTT CAGCCTTCAC CCACAGTTCA CACAAAAGAA 1500

GCACTGGGTT TCATAATGAA CATGTTTCAA ATACCTACCC ATCCGGAAGT GTCTGGGGAG 1560

GAAGACAACT TTCCCTGCCT GGATGAAAAT GAGGAAGCAT TTGAGGCCTG CTTTAAAAAG 1620

AACACAGAGT CATCTGGAGT CTTGGGAATT AAAAGCATCA ACCCTGCGAC GACACCTGCT 1680

TTTTCCATCT TTGAAGACGG CAATAAAGAA AATAACGGGC CCCCGGAGAG CAAAAATAAG 1740

CCTGGAGGGA CCAGATCCTT TGGCGAACGT CCTGCCAGCC GACTTGCTTT AAAACCAAAT 1800

GAAGAAGCCC AGGTAGCAGA AACTTTGGAT GATTGTACTG TCTGGGGCGT GCGCTGTAAT 1860

AAAACCCTGG CCCCCAGTCC CAATAGCACA AGAGATTTCG CACGGGCTGC ACAATTTGCA 1920

TCTACACCTT TTAACGGCTT TCCGGTATAT CTAAGGCCGA CTCTGGAGAA TAAAGAAAAT 1980

ATGATCGCAA ACCGCGCTGC CGACACGCAT CTGAACTCTA GCGAAGAAAA GCCATTGCTG 2040

AGCTCGGAAA ATAAAAAACT AAGCCCAATT CAAGAACACA GCCCGGACCT ACAGGATTTG 2100

CCGGAAGAGA TGCTGTCGAA CACCTCGCTC ATCTTAAAAC CCCAGGGTCC TTGTGGTGGC 2160

CTACTGACTG AGGAAGTGGA ACTGGGCTTG GCTGCTTGTA AAGTGACTGA AATCACCCTC 2220

GCCATGGAGG ACGAGCCAGA GGAAGCCAGT GCTGAGCAAA TGGGACTGCC TGAGCAGAGT 2280

CCGCCGGCCG AAAGTGTGAA ATCGCCAGAC TTCATCGTTG AGAATCCGTG GGACGATCAG 2340

TTGATTCACA GATTTTTATC AAACTTATCT AAGCCTGTAA ATTCCTATCC AAATACTTTT 2400

GAGTGGGCAT CCAATGTTCC AGCAATCAAG TTGAAGACTC AAGTTCATGT GGGTACTGCG 2460

CCGTTCTATA TCGATTGCCT TCTTGGAGAA GGAGCCTTTG CCCATGTTTA TCAAGCAACA 2520

GTATTGAACA TGGATGACCC GAAAAATAAT CAGAAAGTAA TATTAAAGGT CCAGAAACCT 2580

GCCAACCCCT GGGAATTCTA CATAGGAACT CAGTTACTGG AGCGGCTTCA TCCGAACGTC 2640

CGCCATCTGT TTATCCGGTT CTACTCGGCC CATTTGTTTC ACAACGGCAG CGTGTTGGTC 2700

GGAGAGCTCT ACAGCTACGG AACGCTACTG AACGCCATCA ATCTCTACAA AAACACCCCT 2760

GAGAAAACGA TGCCCCAGGC ACTGGTCATG TATTTTGCTC TAAAGATTAT GTTCATGATC 2820

GAGCGACTTC ACGACTGTGA AATCATCCAC GGCGACATTA AACCCGACAA CTTCATCCTC 2880

GGAGAAAGGT TCTTGGAGGA TGACGACTGG ACGGTAGACA GCCCTCCTCA CGGCCTGACC 2940

GTGATCGACC TGGGGCAGAG TATAGATATG ACCCTGTTCC CCAAAGGGAC GGCATTCACG 3000

GGGAGGTGCG AAACGTCCGG TTTCCAGTGT GTCGAAATGC TGAGTCGAAA GCCGTGGAAC 3060

TATCAGACCG ATTACTTCGG AGTCGCTGCA ACGGTCTACT GCATGCTCTT TGGGACTTAC 3120

ATGAAGGTGA AAAACGAACA AGGAGTCTGG AAAGCAGAAG GCATTTTCAA ACGGCTCCCT 3180

CATTCTGAAA TGTGGAATGA CTTTTTTCAC ACTCTGCTGA ATATACCAGA CTGCCATCAC 3240

CTTCCTTCGT TGGGAGCCTT ACGGGAAAAG CTAAAAGTGA TTTTACAGCA ATCCTACGGC 3300

AACAAGATCA AGTCCCTCCG CAAGAGGCTG GTCGTGTTGC TTCTGGAAAA CAAGCGCTCC 3360

CGAAAATAG 3369

Domain Profile

S: 1     leiekeigeGayakvykaeh....dsksgelvalKvekpansWefYIclqlkeRlkeeel  56

         ++i+ ++geGa+a+vy+a+     d k++++v+lKv+kpan+WefYI +ql eRl+ +++

Q: 822   FYIDCLLGEGAFAHVYQATVlnmdDPKNNQKVILKVQKPANPWEFYIGTQLLERLH-PNV  880

         68999**************99998999*****************************.88*

S: 57    lksiieissallfqdasllvleyasygtlldlinkvkevtnkvmdeelvvllivqllkiv  116

          + +i+++sa+lf+++s+lv e++sygtll++in++k++ +k m+++lv++++++++ ++

Q: 881   RHLFIRFYSAHLFHNGSVLVGELYSYGTLLNAINLYKNTPEKTMPQALVMYFALKIMFMI  940

         ************************************************************

S: 117   eklHeveIiHgDlkPdnfllgnrimdkad..kdkeekglkliDfgrsiDmkllpdgtkfk  174

         e+lH++eIiHgD+kPdnf+lg+r+ +  d  +d+  +gl +iD+g+siDm+l+p+gt+f+

Q: 941   ERLHDCEIIHGDIKPDNFILGERFLEDDDwtVDSPPHGLTVIDLGQSIDMTLFPKGTAFT  1000

         ************************87655449****************************

S: 175   gkaktdafeciemlagkswsYqvDlfglaavihvllfgkyleviqeggswklkqkikrll  234

         g+++t++f+c+eml+ k+w+Yq+D+fg+aa+++++lfg+y++v++e+g wk +  +krl+

Q: 1001  GRCETSGFQCVEMLSRKPWNYQTDYFGVAATVYCMLFGTYMKVKNEQGVWKAEGIFKRLP  1060

         ************************************************************

S: 235   kkelwekiferlLNisdastlpsleelveek  265

         ++e+w+++f++lLNi+d+++lpsl+ l+e k

Q: 1061  HSEMWNDFFHTLLNIPDCHHLPSLGALRE-K  1090

         ***************************96.4

Domain Sequence
(FASTA)

FYIDCLLGEG AFAHVYQATV LNMDDPKNNQ KVILKVQKPA NPWEFYIGTQ LLERLHPNVR 60

HLFIRFYSAH LFHNGSVLVG ELYSYGTLLN AINLYKNTPE KTMPQALVMY FALKIMFMIE 120

RLHDCEIIHG DIKPDNFILG ERFLEDDDWT VDSPPHGLTV IDLGQSIDMT LFPKGTAFTG 180

RCETSGFQCV EMLSRKPWNY QTDYFGVAAT VYCMLFGTYM KVKNEQGVWK AEGIFKRLPH 240

SEMWNDFFHT LLNIPDCHHL PSLGALREK 269

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR013212	; Mad3_BUB1_I.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.
IPR015661	; Ser/Thr_kinase_Bub1.

Pfam

PF08311	; Mad3_BUB1_I; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00777

; Mad3_BUB1_I; 1.

Prosites

PS51489	; BUB1_N; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013