EPS-ORA-00025

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-ORA-00025

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	140.1	1.2E-40	282	410	129

Status

Unreviewed

Ensembl Protein

ENSOANP00000020992

UniProt Accession

F6S4D2;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1G

Gene Synonyms/Alias

PPM1G;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOANG00000013295	ENSOANP00000020992	ENSOANT00000020995

Organism

Ornithorhynchus anatinus

Functional Description

Protein Length

410

Protein Sequence
(FASTA)

FQDAHNCIPE LDSETAMFSV YDGHGGEEVA LYCAKYLPEI IKDQKAYKEG KLQKALEDAF 60

LAIDAKLTTE EVIKELAQIA GRPPEDEDEK EKVADEDDVD NEEAALLHEE ATMTIEELLT 120

RYGQNCHKGP PSSKAGTGTG PGEEPGTQGL NGEAGPEEPA GERPVEENGP AAEADAGISS 180

GPRRGARAEA DRGDEPAVPS TGEAGPSCSS SPAKPPRAAK SKFFEDSEDE SDEAEEEEEE 240

DSEECSEDED GYSSEEVENE EDEDDTEEAE EEEEEEEMML PGMEGKEEPG SDSGTTAVVA 300

LIRGKQLIVA NAGDSRCVVS EAGKALDMSY DHKPEDELEL ARIKNAGGKV TMDGRVNGGL 360

NLSRAIGDHF YKRNKNLPPE EQMISALPDI KVLTLNEDHD FMVIACDGIW 410

Nucleotide Sequence
(FASTA)

TTCCAGGATG CCCACAACTG TATCCCCGAG CTGGACAGCG AGACAGCCAT GTTTTCGGTC 60

TACGACGGAC ACGGAGGGGA AGAAGTTGCT CTTTATTGTG CCAAGTACCT CCCTGAAATC 120

ATCAAAGACC AGAAGGCTTA CAAGGAAGGC AAGCTACAGA AGGCCTTGGA AGATGCTTTC 180

TTGGCTATTG ACGCCAAACT AACCACTGAG GAGGTCATCA AGGAGCTGGC CCAGATCGCG 240

GGGCGGCCTC CCGAGGATGA AGATGAAAAG GAGAAAGTAG CCGATGAGGA CGACGTGGAC 300

AATGAGGAAG CGGCATTGCT ACACGAAGAG GCCACCATGA CTATCGAAGA GCTGTTGACA 360

CGCTATGGGC AGAACTGCCA TAAGGGCCCT CCCTCCAGCA AGGCGGGCAC TGGAACGGGG 420

CCAGGCGAGG AGCCGGGGAC CCAGGGTCTC AATGGCGAGG CGGGGCCCGA GGAGCCGGCC 480

GGGGAGCGAC CCGTAGAGGA GAACGGGCCC GCGGCAGAGG CAGACGCAGG CATCTCCTCC 540

GGTCCGCGGC GCGGGGCTAG GGCCGAGGCG GACCGGGGCG ACGAGCCCGC CGTCCCCTCC 600

ACTGGCGAGG CGGGGCCCTC CTGCTCTTCC TCCCCTGCCA AGCCTCCCCG GGCTGCTAAG 660

TCCAAGTTCT TTGAGGACAG TGAGGACGAA TCGGATGAGG CAGAAGAAGA AGAGGAGGAG 720

GACAGCGAGG AGTGCAGCGA GGATGAAGAC GGCTACAGCA GCGAAGAAGT GGAGAACGAG 780

GAGGATGAGG ACGACACAGA AGAGGCGGAG GAGGAAGAAG AGGAGGAAGA GATGATGCTG 840

CCCGGCATGG AAGGCAAAGA GGAGCCCGGT TCAGACAGCG GCACCACGGC AGTGGTGGCC 900

CTGATCCGGG GGAAGCAGCT GATCGTGGCC AACGCCGGGG ACTCCCGCTG CGTCGTGTCC 960

GAGGCCGGCA AGGCCCTGGA CATGTCGTAC GACCACAAGC CCGAAGATGA GCTGGAGCTG 1020

GCCCGCATCA AGAACGCCGG TGGCAAGGTC ACTATGGACG GACGAGTCAA CGGCGGCCTC 1080

AACCTTTCCC GGGCTATCGG CGACCACTTC TACAAGCGGA ACAAGAACCT CCCACCCGAG 1140

GAGCAGATGA TCTCAGCGCT GCCTGACATC AAGGTGCTGA CGCTCAACGA GGACCACGAC 1200

TTTATGGTCA TTGCCTGTGA TGGGATCTGG 1230

Domain Profile

S: 92    vleeksldidksGstavvalikdsklyvanvGdSravLcrngkavelssdHkpsredEle  151

          +e k++  + sG+tavvali++++l+van+GdSr+v +  gka+ +s dHkp+ e El+

Q: 282   GMEGKEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDELELA  341

         34444445556*************************************************

S: 152   RieeaggsvilkdgaRvlGvLavsRalGdlylk.........pyvtpePevtshrltsed  202

         Ri++agg+v+ +   Rv+G L++sRa+Gd ++k         +++++ P++ + +l++++

Q: 342   RIKNAGGKVTMDG--RVNGGLNLSRAIGDHFYKrnknlppeeQMISALPDIKVLTLNEDH  399

         ************9..*********************************************

S: 203   efliLasDGlw  213

         +f+++a+DG+w

Q: 400   DFMVIACDGIW  410

         ***********

Domain Sequence
(FASTA)

GMEGKEEPGS DSGTTAVVAL IRGKQLIVAN AGDSRCVVSE AGKALDMSYD HKPEDELELA 60

RIKNAGGKVT MDGRVNGGLN LSRAIGDHFY KRNKNLPPEE QMISALPDIK VLTLNEDHDF 120

MVIACDGIW 129

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0046872	; F:metal ion binding
GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0007050	; P:cell cycle arrest
GO:0035970	; P:peptidyl-threonine dephosphorylation

KEGG

InterPros

IPR001932	; PP2C-like.
IPR000222	; PP2C_Mn2_Asp60_BS.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481

; PP2C; 2.

SMARTs

SM00332

; PP2Cc; 1.

Prosites

PS01032

; PP2C; 1.

Prints

Created Date

20-Feb-2013