EKS-ORA-00182

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORA-00182

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	523.7	9.8E-158	4	287	284

Status

Unreviewed

Ensembl Protein

ENSOANP00000022035

UniProt Accession

F6USI0;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL1

Gene Synonyms/Alias

CDKL1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOANG00000013976	ENSOANP00000022035	ENSOANT00000022039

Organism

Ornithorhynchus anatinus

Functional Description

Protein Length

352

Protein Sequence
(FASTA)

MEKYEKIGKI GEGSYGVVFK CRNRDTGQIV AIKRFMESED DPVIKKIALR EIRMLKQLKH 60

PNLVNLLEVF RRKRKLHLVF EYCDHTVLHE LDRFQRGVPE QLVKSITWQT LQAVNFCHKH 120

SCIHRDVKPE NILITKHSVI KLCDFGFARL LTGPSDYYTD YVATRWYRSP ELLVGDTQYG 180

PPVDVWAVGC VFAELLSGSP LWPGKSDVDQ LYLIRKTLGD LIPRHQQVFS TNQFFSGVRI 240

PDPENTEPLE SKFPNISSPA LGLMKGCLHM DPAARLTCEQ LLQLPYFNSL RDTEDLAREQ 300

ERPSRRPPRL SRKHLPALQY LPQLTSSSVL PTLENKKYYC NTRKLNYRFP NI 352

Nucleotide Sequence
(FASTA)

ATGGAGAAAT ACGAGAAAAT TGGAAAAATT GGGGAAGGAT CCTACGGAGT GGTTTTCAAA 60

TGCCGAAACC GAGACACCGG CCAGATAGTG GCTATAAAAA GGTTTATGGA GTCAGAAGAT 120

GACCCGGTCA TAAAGAAAAT TGCCCTTCGA GAGATTCGCA TGCTCAAGCA ACTCAAGCAT 180

CCAAACCTGG TCAACCTTCT TGAAGTCTTC AGGAGAAAAC GGAAACTTCA CTTGGTGTTC 240

GAGTACTGTG ACCACACGGT TCTCCACGAG CTGGACAGGT TCCAAAGAGG AGTCCCGGAG 300

CAGCTAGTGA AGAGCATAAC CTGGCAAACA CTCCAGGCTG TCAACTTCTG CCATAAACAC 360

AGCTGCATAC ACAGAGATGT GAAGCCTGAA AACATCCTCA TCACAAAGCA CTCGGTCATT 420

AAGCTTTGTG ACTTCGGATT TGCTCGGCTT TTGACCGGCC CCAGTGACTA CTACACAGAC 480

TACGTGGCCA CCCGGTGGTA TCGCTCCCCG GAGCTGCTGG TGGGGGACAC TCAGTACGGC 540

CCCCCCGTGG ACGTCTGGGC AGTCGGCTGT GTCTTTGCGG AACTGCTGTC GGGGTCTCCC 600

TTGTGGCCGG GGAAATCGGA CGTGGACCAG CTGTACCTGA TCAGAAAAAC CCTGGGAGAC 660

CTCATTCCCA GGCACCAGCA AGTGTTTAGC ACGAACCAGT TCTTCAGCGG GGTGAGGATT 720

CCAGACCCAG AGAATACGGA GCCCCTGGAA TCGAAATTCC CAAACATTTC CTCTCCTGCT 780

CTGGGGCTGA TGAAGGGCTG CCTCCACATG GACCCTGCCG CACGACTGAC GTGTGAGCAG 840

CTGCTGCAGC TCCCGTACTT CAACAGCCTC CGGGACACGG AAGACCTGGC CAGGGAACAG 900

GAGAGACCCT CCCGGAGACC CCCGAGGCTG AGTCGGAAGC ACCTCCCGGC GTTACAGTAC 960

CTGCCTCAGT TGACCAGTAG TAGCGTCTTG CCCACTTTGG AGAACAAGAA ATACTACTGC 1020

AACACAAGGA AGCTTAACTA TCGCTTTCCC AACATTTAA 1059

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         yek+gk+GeGsyGvv+kcrn+dtgqivaik+f+esedd+++kkialrei++lkqlkh+nl

Q: 4     YEKIGKIGEGSYGVVFKCRNRDTGQIVAIKRFMESEDDPVIKKIALREIRMLKQLKHPNL  63

         9***********************************************************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnllevfrrk+kl+lvfey+d+tvl+el+r+++Gv+e+lvk+i++q+l+a++fchk+ +i

Q: 64    VNLLEVFRRKRKLHLVFEYCDHTVLHELDRFQRGVPEQLVKSITWQTLQAVNFCHKHSCI  123

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrd+kpenili+k++v+klcdfGfarll++p+d+ytdyvatrwyr+pellvgdt+yG++v

Q: 124   HRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQYGPPV  183

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         dvwa+Gc++aell+G+pl+pgksdvdqly+irktlG+liprhq++fs+n++f+Gv++p++

Q: 184   DVWAVGCVFAELLSGSPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQFFSGVRIPDP  243

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         e++e+le+k+p++++ +l l+k+cl++dpa rl+ce+ll+ +yf

Q: 244   ENTEPLESKFPNISSPALGLMKGCLHMDPAARLTCEQLLQLPYF  287

         ****************************************9998

Domain Sequence
(FASTA)

YEKIGKIGEG SYGVVFKCRN RDTGQIVAIK RFMESEDDPV IKKIALREIR MLKQLKHPNL 60

VNLLEVFRRK RKLHLVFEYC DHTVLHELDR FQRGVPEQLV KSITWQTLQA VNFCHKHSCI 120

HRDVKPENIL ITKHSVIKLC DFGFARLLTG PSDYYTDYVA TRWYRSPELL VGDTQYGPPV 180

DVWAVGCVFA ELLSGSPLWP GKSDVDQLYL IRKTLGDLIP RHQQVFSTNQ FFSGVRIPDP 240

ENTEPLESKF PNISSPALGL MKGCLHMDPA ARLTCEQLLQ LPYF 284

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013