EKS-ORC-00136

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORC-00136

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/RIO	274.8	6.3E-82	96	318	223

Status

Unreviewed

Ensembl Protein

ENSOCUP00000001417

UniProt Accession

G1SFU7;

Protein Name

Protein Synonyms/Alias

Gene Name

RIOK2

Gene Synonyms/Alias

RIOK2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOCUG00000001656	ENSOCUP00000001417	ENSOCUT00000001656

Organism

Oryctolagus cuniculus

Functional Description

Protein Length

552

Protein Sequence
(FASTA)

MGKVNVAKLR YMSRDDFRVL TAVEMGMKNH EIVPCSLIAS IASLKHGGCN KVLRELVKHK 60

LIAWERTKTV QGYRLTNAGY DYLALKTLSS RQVVESVGNQ MGVGKESDIY IVANEEGQQF 120

ALKLHRLGRT SFRNLKNKRD YHKHRHNVSW LYLSRLSAMK EFAYMKALHE RKFPVPKPID 180

YNRHAGVMEL INGYPLCQIH HVEDPASVYD EAMELIVRLA NHGLIHGDFN EFNLILDKDD 240

HITMIDFPQM VSTSHPNAEW YFDRDVKCVR DFFIKRFNYE SELYPTFSDI RREDSLDVEV 300

SASGYTKEMQ VDDELLHPLG PDDGNSATER GSDCSLSDEE ASEEAKVCRS ENESEKSSVD 360

EASGHCPRSP GELEQTKQDS LFGECAGIHV FEMTGFSQAL EEVKGQVVES NLTTELSGEK 420

NRTENGTWQD GLTGPGGVPA GPEECEDECP DLIALSSLNK EFRPFRDQES LGNLTQCRTR 480

TLSVTSAGSV VSCSTIPPEL VKQKVKRQLT RQQKSAVRRR LQKGEANIFT KQRRENMQNI 540

KSSLEAASFW GE 552

Nucleotide Sequence
(FASTA)

ATGGGCAAGG TGAATGTGGC CAAGTTGCGC TACATGAGCC GGGATGACTT CAGGGTCCTG 60

ACAGCGGTTG AAATGGGCAT GAAGAACCAT GAAATAGTTC CCTGCAGTTT GATTGCTTCT 120

ATAGCCAGCC TTAAACATGG TGGCTGTAAT AAAGTTTTAA GAGAATTAGT GAAACATAAA 180

CTCATAGCCT GGGAGCGTAC CAAAACTGTC CAGGGCTATC GGCTGACAAA TGCAGGCTAT 240

GACTACCTCG CTTTGAAAAC ACTTTCTTCT AGACAGGTAG TCGAGTCTGT TGGAAACCAG 300

ATGGGTGTTG GCAAAGAATC AGATATTTAC ATCGTTGCAA ATGAAGAAGG ACAGCAGTTT 360

GCATTGAAGC TTCATAGACT AGGAAGAACT TCCTTCCGAA ATTTGAAAAA CAAGCGTGAC 420

TACCATAAAC ACAGGCACAA TGTCTCTTGG CTTTATTTGT CTCGTCTCTC TGCCATGAAG 480

GAGTTTGCCT ATATGAAGGC ATTACATGAG AGGAAATTTC CAGTTCCAAA ACCAATTGAT 540

TACAATCGCC ACGCAGGGGT CATGGAGCTC ATAAATGGCT ATCCTTTGTG TCAGATACAT 600

CATGTTGAAG ACCCTGCATC TGTATATGAT GAAGCAATGG AACTAATTGT CAGACTTGCA 660

AATCATGGGC TGATTCATGG AGATTTCAAT GAATTCAATC TCATTTTGGA TAAAGATGAC 720

CATATCACCA TGATTGATTT TCCACAGATG GTTTCAACTT CTCATCCCAA TGCTGAGTGG 780

TATTTCGACA GAGATGTTAA ATGTGTGAGA GATTTCTTCA TCAAACGTTT CAACTATGAA 840

AGTGAGCTTT ATCCAACATT TAGTGACATC AGGAGGGAAG ACTCTCTGGA CGTGGAGGTC 900

TCTGCCAGCG GCTACACAAA GGAGATGCAG GTGGACGATG AACTGCTGCA TCCACTCGGG 960

CCAGATGATG GGAACTCCGC CACAGAGCGG GGGTCTGACT GCTCACTTTC TGATGAAGAG 1020

GCATCGGAAG AAGCAAAGGT CTGCAGGTCA GAGAATGAGA GTGAAAAGAG CTCTGTGGAT 1080

GAAGCAAGTG GCCACTGTCC CAGGTCACCT GGAGAACTCG AGCAAACAAA GCAGGACAGT 1140

TTATTCGGGG AGTGTGCTGG CATACACGTG TTTGAAATGA CTGGATTCAG TCAGGCTTTG 1200

GAGGAAGTGA AAGGACAGGT TGTTGAAAGC AATTTAACAA CTGAGCTTTC TGGGGAGAAA 1260

AACAGAACTG AAAATGGCAC GTGGCAGGAT GGTCTGACTG GTCCCGGAGG AGTCCCTGCT 1320

GGCCCTGAGG AGTGTGAAGA CGAGTGCCCT GATCTGATTG CACTGTCGTC ATTAAACAAG 1380

GAATTCAGGC CTTTCAGAGA TCAAGAAAGT TTGGGAAATC TTACTCAGTG TAGAACAAGA 1440

ACTCTGAGTG TTACTTCTGC AGGCAGTGTT GTAAGCTGTT CAACAATTCC TCCGGAACTG 1500

GTAAAACAGA AGGTAAAACG TCAATTGACA AGACAGCAAA AATCAGCTGT GAGACGTCGA 1560

TTACAGAAAG GAGAAGCAAA TATATTTACT AAGCAAAGGA GAGAAAACAT GCAAAATATT 1620

AAATCAAGTT TGGAAGCAGC CAGCTTTTGG GGAGAATAA 1659

Domain Profile

S: 2     svgntigvgkesdvykvsekngeeraiKiy...ktsllvlknrdkYvdgefrfkksrska  58

         svgn++gvgkesd+y v++++g+++a+K++   +ts+++lkn+++Y       +k+r+++

Q: 96    SVGNQMGVGKESDIYIVANEEGQQFALKLHrlgRTSFRNLKNKRDY-------HKHRHNV  148

         79********************************************.......9******

S: 59    nprklsrlwAeKEfrnlkrlyekgvpvPepidlkrhvlvmeligrdgypapklkdvklke  118

         ++++lsrl+A+KEf+++k+l+e+++pvP+pid++rh+ vmeli  +gyp+++++    +

Q: 149   SWLYLSRLSAMKEFAYMKALHERKFPVPKPIDYNRHAGVMELI--NGYPLCQIH----HV  202

         *******************************************..*********....9*

S: 119   eeikelYsdllalivklynegrLvHaDlsEfnill.eddklvliDvsqsveieHpdalef  177

         e+ +++Y+++++liv+l+n+g L+H+D++Efn++l +dd++++iD++q+v+++Hp+a+++

Q: 203   EDPASVYDEAMELIVRLANHG-LIHGDFNEFNLILdKDDHITMIDFPQMVSTSHPNAEWY  261

         *********************.*************899**********************

S: 178   lrrDvknvkefFkkklvy.........dvlrerelfelvsasgltkekeaddeilea  225

         ++rDvk+v++fF k++ y         d++re++l+ +vsasg+tke++ dde+l++

Q: 262   FDRDVKCVRDFFIKRFNYeselyptfsDIRREDSLDVEVSASGYTKEMQVDDELLHP  318

         *****************************************************9987

Domain Sequence
(FASTA)

SVGNQMGVGK ESDIYIVANE EGQQFALKLH RLGRTSFRNL KNKRDYHKHR HNVSWLYLSR 60

LSAMKEFAYM KALHERKFPV PKPIDYNRHA GVMELINGYP LCQIHHVEDP ASVYDEAMEL 120

IVRLANHGLI HGDFNEFNLI LDKDDHITMI DFPQMVSTSH PNAEWYFDRD VKCVRDFFIK 180

RFNYESELYP TFSDIRREDS LDVEVSASGY TKEMQVDDEL LHP 223

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR018934	; RIO-like_kinase.
IPR015285	; RIO2_kinase_winged_hlx_N.
IPR018935	; RIO_kinase_CS.
IPR011991	; WHTH_trsnscrt_rep_DNA-bd.

Pfam

PF01163	; RIO1; 1.
PF09202	; Rio2_N; 1.

SMARTs

Prosites

PS01245

; RIO1; 1.

Prints

Created Date

20-Feb-2013