EKS-ORC-00094

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORC-00094

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/TSSK	359.2	1.7E-107	27	305	279

Status

Unreviewed

Ensembl Protein

ENSOCUP00000002519

UniProt Accession

G1SIK7;

Protein Name

Protein Synonyms/Alias

Gene Name

TSSK4

Gene Synonyms/Alias

TSSK4;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOCUG00000002899	ENSOCUP00000002519	ENSOCUT00000002899

Organism

Oryctolagus cuniculus

Functional Description

Protein Length

342

Protein Sequence
(FASTA)

MGKGDAVEAA AAPATLAYRS VMEEYGYEVG KVIGNGSYGT VYEAYYTKQK VMVAVKIISK 60

KKASEDYLNK FLPREIQVMK VLRHKYLINF YQAIETTSRV YIILELAQGG DVLEWIQRYG 120

ACSEPLAGKW FSQMALGIAY LHSKGIVHRL TPSLSAAGRD LKLENLLLDK RENVKISDFG 180

FAKMVPPNQP ARSSSSYRQM NCFSHLSQTY CGSFAYACPE ILLGLPYNPF LSDTWSMGVI 240

LYTLVVARLP FDDTNLKKLL KETQKEVSFP QNNAISQECK NLVLHMLCQA AKRATILDIL 300

KDPWVLKFQP EQPTNEIRLL EAMCQPTTSS TSNRQQSLGN TT 342

Nucleotide Sequence
(FASTA)

ATGGGGAAGG GAGATGCGGT GGAGGCGGCG GCAGCACCAG CCACTCTGGC TTACCGATCT 60

GTCATGGAGG AGTATGGCTA TGAGGTGGGC AAGGTCATTG GCAATGGCTC CTACGGGACA 120

GTGTACGAGG CTTATTACAC AAAGCAGAAG GTCATGGTGG CCGTCAAGAT CATCTCAAAG 180

AAGAAGGCCT CCGAGGATTA TCTAAACAAG TTCCTGCCCC GTGAGATACA GGTAATGAAA 240

GTCTTGCGGC ACAAGTACCT CATCAACTTC TATCAGGCCA TCGAGACCAC GTCCCGCGTG 300

TACATCATCC TAGAGCTGGC ACAAGGTGGA GACGTCCTCG AGTGGATCCA GCGCTATGGG 360

GCCTGCTCTG AGCCCCTTGC TGGCAAGTGG TTCTCCCAGA TGGCCCTGGG CATCGCCTAC 420

CTGCACAGCA AGGGCATCGT GCACCGCCTG ACCCCCAGCC TTTCTGCTGC TGGTAGGGAC 480

TTAAAGTTGG AGAACTTGTT GTTGGACAAG CGAGAGAATG TGAAGATATC GGACTTTGGC 540

TTCGCCAAGA TGGTGCCTCC TAACCAGCCT GCGCGTAGTA GCTCTTCTTA CCGCCAAATG 600

AACTGCTTTT CCCACCTCAG CCAGACCTAC TGTGGCAGCT TTGCATACGC CTGCCCCGAG 660

ATCTTGCTAG GCTTGCCCTA CAACCCTTTC CTGTCGGACA CCTGGAGCAT GGGAGTCATC 720

CTCTATACTC TGGTGGTCGC CCGTCTGCCC TTCGATGACA CCAACCTCAA GAAGCTGCTC 780

AAGGAGACTC AGAAGGAGGT CTCTTTCCCG CAGAACAACG CCATCTCCCA GGAGTGCAAG 840

AACCTGGTCC TTCATATGCT ATGCCAAGCA GCCAAGCGTG CCACCATCCT GGACATCCTC 900

AAGGATCCCT GGGTGCTCAA GTTCCAGCCT GAGCAACCCA CCAATGAGAT CAGGCTGCTA 960

GAGGCCATGT GCCAGCCCAC CACCAGCAGC ACCAGCAATC GGCAGCAATC CTTGGGCAAC 1020

ACAACCTGA 1029

Domain Profile

S: 1     lklgkkiGeGsyskvkeaysekkklkvavkiidkkkapedyvkkFlPReleilktlkhkn  60

         +++gk+iG+Gsy++v+eay++k+k++vavkii+kkka+edy++kFlPRe++++k+l+hk+

Q: 27    YEVGKVIGNGSYGTVYEAYYTKQKVMVAVKIISKKKASEDYLNKFLPREIQVMKVLRHKY  86

         799*********************************************************

S: 61    ivklyeiietsdkiylvlelaaqgdllelikesgaleeeearklfsqlvsavkylhsldi  120

         ++++y++iet++++y++lela++gd+le+i+++ga++e  a+k+fsq++ +++ylhs++i

Q: 87    LINFYQAIETTSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQMALGIAYLHSKGI  146

         ************************************************************

S: 121   vhR..........DlkcenilldkkenvklsDFgFakkvk..............rsksel  156

         vhR          Dlk+en+lldk+envk+sDFgFak+v+              ++ s+l

Q: 147   VHRltpslsaagrDLKLENLLLDKRENVKISDFGFAKMVPpnqparssssyrqmNCFSHL  206

         **55555555555***************************99999999888654499***

S: 157   sktfCGsaaYaaPevlrgikydpklsDvWslGvilyvmvvgklPfddsdikkllrsqkkr  216

         s+t+CGs+aYa+Pe+l g++y+p+lsD+Ws+Gvily++vv++lPfdd+++kkll+ ++++

Q: 207   SQTYCGSFAYACPEILLGLPYNPFLSDTWSMGVILYTLVVARLPFDDTNLKKLLK-ETQK  265

         ******************************************************9.****

S: 217   kvkfpksltlseeckdlilellqldakkRltikevlessWl  257

         +v+fp++  +s+eck+l+l++l  +a kR+ti ++l+++W+

Q: 266   EVSFPQNNAISQECKNLVLHMLC-QAAKRATILDILKDPWV  305

         **********************8.89**************6

Domain Sequence
(FASTA)

YEVGKVIGNG SYGTVYEAYY TKQKVMVAVK IISKKKASED YLNKFLPREI QVMKVLRHKY 60

LINFYQAIET TSRVYIILEL AQGGDVLEWI QRYGACSEPL AGKWFSQMAL GIAYLHSKGI 120

VHRLTPSLSA AGRDLKLENL LLDKRENVKI SDFGFAKMVP PNQPARSSSS YRQMNCFSHL 180

SQTYCGSFAY ACPEILLGLP YNPFLSDTWS MGVILYTLVV ARLPFDDTNL KKLLKETQKE 240

VSFPQNNAIS QECKNLVLHM LCQAAKRATI LDILKDPWV 279

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Dasypus novemcinctus"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Tarsius syrichta"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>

Gene Ontology

GO:0019861	; C:flagellum
GO:0005524	; F:ATP binding
GO:0004672	; F:protein kinase activity
GO:0032793	; P:positive regulation of CREB transcription factor activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013