EPS-ORC-00015

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-ORC-00015

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/aDSP	69.8	2.5E-19	93	200	108

Status

Unreviewed

Ensembl Protein

ENSOCUP00000003165

UniProt Accession

G1SK51;

Protein Name

Protein Synonyms/Alias

Gene Name

DUSP11

Gene Synonyms/Alias

DUSP11;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOCUG00000003647	ENSOCUP00000003165	ENSOCUT00000003648

Organism

Oryctolagus cuniculus

Functional Description

Protein Length

331

Protein Sequence
(FASTA)

MSQWHHARSD RSRGRDSSGR SSGKKKGKNH IPERWKDYLP VGQRMPGTRF IAFKVPLQKN 60

FEKNLAPEEC FSLLDLFNKI REQNEELGLI IDLTYTQRYY KPEDLPETIS YLKIFTVGHQ 120

VPDDDTILKF KHAVNGFVKE NKDNDKLIGV HCTHGLNRTG YLICRYLIDV QGMRPDDAIE 180

LFNRCRGHCL ERQNYIDDLQ HGPIRKSRKS RVSRSSGFED SAYLMDPTHS TDKAVHQGHR 240

QSLHRNHGHP APSRHVRNQT PNLQHSIRKF SQNHVYQRRR LPPPGPPGED YSWKRYTWDV 300

KTSGRRTACS SRWYSDTYHR LSHPAYWGWT E 331

Nucleotide Sequence
(FASTA)

ATGAGCCAGT GGCATCATGC CCGCAGTGAT CGGAGCCGGG GACGCGACTC TTCCGGACGT 60

TCCTCAGGCA AGAAGAAGGG CAAAAACCAC ATTCCGGAAA GGTGGAAAGA CTATCTCCCA 120

GTTGGACAGC GGATGCCTGG AACTCGTTTC ATCGCTTTCA AAGTTCCTTT GCAAAAGAAT 180

TTTGAAAAGA ACCTTGCTCC AGAAGAATGC TTTTCCCTTT TGGATCTTTT TAACAAGATC 240

CGAGAACAAA ATGAAGAGCT TGGGCTTATT ATTGATTTAA CATATACTCA ACGCTATTAT 300

AAACCAGAGG ACTTGCCAGA AACTATTTCT TACTTAAAAA TTTTTACAGT TGGGCATCAG 360

GTGCCTGATG ATGACACTAT TTTAAAATTC AAACATGCTG TTAATGGATT TGTGAAAGAA 420

AATAAAGATA ATGACAAACT TATTGGTGTC CACTGTACCC ATGGTTTAAA CAGGACTGGC 480

TACCTCATCT GCAGATATTT GATTGATGTA CAAGGCATGA GGCCAGATGA TGCAATTGAA 540

TTGTTCAATC GGTGTCGTGG ACATTGCTTA GAAAGGCAGA ACTACATTGA CGACTTGCAG 600

CATGGTCCTA TCAGAAAAAG TCGAAAATCC AGGGTATCCA GATCGAGTGG TTTTGAGGAC 660

TCAGCATATC TCATGGACCC AACCCACAGT ACTGATAAGG CTGTTCACCA GGGACATAGA 720

CAGAGCCTAC ATCGGAACCA TGGCCACCCA GCACCTTCTC GGCACGTCCG TAACCAGACC 780

CCAAATTTGC AACATTCTAT CAGGAAATTT TCACAAAATC ACGTTTACCA GAGACGCCGC 840

CTCCCTCCCC CCGGCCCCCC TGGAGAGGAC TATTCCTGGA AGAGATACAC CTGGGACGTG 900

AAGACCAGCG GCAGGCGCAC AGCCTGCAGT AGCAGGTGGT ACTCGGACAC TTACCACAGA 960

CTGTCCCATC CGGCCTACTG GGGATGGACC GAGTGA 996

Domain Profile

S: 32    inaslsvikvqviPeylikkgityknipvdDsdvtdllqyfdeaaefideakekggkvlv  91

         ++ +    k +  Pe +   +i  ++ +v D+d   +l++ ++++ f++e+k++++ + v

Q: 93    LTYTQRYYKPEDLPETISYLKIFTVGHQVPDDD--TILKFKHAVNGFVKENKDNDKLIGV  150

         455555555556666666555555555666655..59***********************

S: 92    HCaaGvsRSatlvlaYLmkveglslsdAieavkrkrpsiepnegfleQLl  141

         HC++G++R+++l++ YL++v+g++ +dAie ++r+r+++ ++++++  L

Q: 151   HCTHGLNRTGYLICRYLIDVQGMRPDDAIELFNRCRGHCLERQNYIDDLQ  200

         *********************************************99886

Domain Sequence
(FASTA)

LTYTQRYYKP EDLPETISYL KIFTVGHQVP DDDTILKFKH AVNGFVKENK DNDKLIGVHC 60

THGLNRTGYL ICRYLIDVQG MRPDDAIELF NRCRGHCLER QNYIDDLQ 108

Keyword

Complete proteome; Hydrolase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Taeniopygia guttata"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0004725	; F:protein tyrosine phosphatase activity
GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0035335	; P:peptidyl-tyrosine dephosphorylation

KEGG

InterPros

IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR000387	; Tyr/Dual-specificity_Pase.
IPR016130	; Tyr_Pase_AS.

Pfam

PF00782

; DSPc; 1.

SMARTs

Prosites

PS00383	; TYR_PHOSPHATASE_1; 1.
PS50056	; TYR_PHOSPHATASE_2; 1.

Prints

Created Date

20-Feb-2013