EPS-ORC-00128

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-ORC-00128

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PDP	402.4	5.7E-121	287	498	212

Status

Unreviewed

Ensembl Protein

ENSOCUP00000003416

UniProt Accession

G1SKR5;

Protein Name

Protein Synonyms/Alias

Gene Name

PDP1

Gene Synonyms/Alias

PDP1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOCUG00000003939	ENSOCUP00000003416	ENSOCUT00000003938

Organism

Oryctolagus cuniculus

Functional Description

Protein Length

596

Protein Sequence
(FASTA)

MSISALPSMG RCCCRCCCPR GLWMLSAPCC DDRRMCVCPG PRRSGIPIRS SSLPLFSDAM 60

PAPTQLFFPL VRNCELSRIY GTACYCHHKH LCCPSPYLPQ SRLRYMPHPA YATFCRPKEN 120

WWQYTHGRRY ASTPQKFYLT PPQVNSILKA NEYSFKVPEF DGKNVSSILG FDSNQLPANA 180

PIEDRRSAAT CLQTRGMLLG VFDGHAGCAC SQAVSERLFY YIAVSLLPHE TLLEIENAVE 240

SGRALLPILQ WHKHPNDYFS KEASKLYFNS LRTYWQELID LNTGESTDID VKEALINAFK 300

RLDNDISLEA QVGDPNSFLN YLVLRVAFSG ATACVAHVDG VDLHVANTGD SRAMLGVQEE 360

DGSWSAVTLS NDHNAQNERE LERLKLEHPK NEAKSVVKQD RLLGLLMPFR AFGDVKFKWS 420

IDLQKRVIES GPDQLNDNEY TKFIPPNYHT PPYLTAEPEV TYHRLRPQDK FLVLATDGLW 480

ETMHRQDVVR IVGEYLTGMH HQQPIAVGGY KVTLGQMHGL LTERRAKMSS VFEDQNAATH 540

LIRHAVGNNE FGAVDHERLS KMLSLPEELA RMYRDDITII VVQFNSHVVG AYQNQE 596

Nucleotide Sequence
(FASTA)

ATGAGCATCT CTGCCTTGCC TTCAATGGGC CGGTGCTGCT GTCGCTGCTG CTGTCCGCGC 60

GGGTTGTGGA TGTTGTCGGC TCCGTGTTGT GATGACAGGA GAATGTGTGT GTGTCCCGGG 120

CCCAGACGAA GTGGAATCCC CATCAGAAGT TCCAGCCTGC CGCTCTTCTC TGATGCCATG 180

CCAGCACCAA CTCAACTGTT CTTTCCTCTG GTCCGTAACT GTGAGCTGAG CAGGATCTAT 240

GGCACTGCCT GTTACTGCCA CCACAAACAT CTCTGCTGTC CGTCACCCTA CCTTCCTCAG 300

AGTCGTCTGA GATACATGCC CCATCCAGCA TATGCTACCT TTTGTAGGCC AAAGGAGAAT 360

TGGTGGCAGT ACACCCATGG AAGGAGATAT GCTTCCACAC CACAGAAATT TTACCTCACA 420

CCTCCACAAG TCAACAGCAT CCTTAAAGCT AATGAGTACA GTTTCAAAGT CCCAGAATTT 480

GATGGCAAAA ACGTCAGTTC CATCCTTGGA TTTGACAGCA ATCAGCTGCC TGCAAACGCA 540

CCCATCGAGG ACCGGAGAAG CGCAGCAACC TGCTTGCAGA CCAGAGGAAT GCTTTTAGGG 600

GTTTTTGATG GCCACGCAGG CTGTGCATGT TCCCAGGCAG TCAGTGAAAG ACTCTTTTAT 660

TATATTGCTG TCTCTTTGTT ACCCCATGAG ACTTTGCTAG AGATTGAGAA TGCAGTGGAG 720

AGTGGTCGGG CACTGCTACC CATCCTCCAG TGGCATAAGC ACCCCAATGA TTACTTCAGC 780

AAGGAGGCAT CCAAATTGTA TTTCAATAGC CTGAGGACTT ACTGGCAAGA GCTCATAGAC 840

CTCAACACTG GTGAGTCGAC TGATATTGAT GTTAAGGAAG CTTTAATTAA TGCTTTCAAG 900

AGGCTTGATA ATGACATCTC CTTGGAAGCT CAAGTTGGTG ATCCTAATTC TTTCCTCAAT 960

TACCTGGTGC TTCGAGTGGC ATTTTCTGGG GCTACTGCTT GTGTGGCCCA TGTGGATGGT 1020

GTTGACCTTC ATGTGGCCAA TACTGGTGAT AGCAGAGCCA TGCTCGGTGT GCAGGAAGAG 1080

GATGGCTCTT GGTCAGCAGT CACACTCTCT AATGACCACA ATGCTCAGAA TGAAAGAGAA 1140

CTAGAACGAC TCAAATTGGA ACACCCAAAG AATGAGGCCA AGAGTGTGGT GAAACAGGAT 1200

CGACTGCTTG GGTTGCTGAT GCCTTTTAGG GCTTTTGGAG ATGTAAAGTT CAAATGGAGC 1260

ATTGACCTTC AAAAGAGAGT AATAGAATCT GGCCCAGACC AATTGAATGA CAATGAATAT 1320

ACCAAGTTTA TCCCTCCTAA TTATCACACA CCTCCTTATC TCACTGCTGA GCCAGAGGTA 1380

ACTTACCACC GATTAAGGCC ACAGGATAAG TTTCTAGTGT TGGCCACTGA TGGACTGTGG 1440

GAGACTATGC ATAGGCAGGA TGTGGTTAGG ATTGTGGGTG AGTACCTGAC TGGTATGCAT 1500

CACCAGCAGC CGATAGCGGT TGGTGGCTAC AAGGTGACTC TGGGACAGAT GCATGGCCTT 1560

TTAACAGAAA GGAGAGCCAA GATGTCCTCG GTATTTGAGG ATCAGAATGC AGCAACCCAT 1620

CTCATTCGTC ATGCTGTAGG CAACAACGAG TTTGGAGCTG TTGATCATGA GCGCCTTTCC 1680

AAAATGCTTA GTCTTCCTGA AGAGCTCGCT CGGATGTACA GGGATGACAT TACAATCATT 1740

GTCGTTCAGT TCAATTCTCA TGTTGTAGGG GCGTATCAAA ACCAGGAA 1788

Domain Profile

S: 1     tdidvkealvnafkrldedisleaqvsdedevlrylvlrvalsGataclahvdGvdlhva  60

         tdidvkeal+nafkrld+disleaqv+d++++l+ylvlrva+sGatac+ahvdGvdlhva

Q: 287   TDIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVA  346

         699*********************************************************

S: 61    ntGdsravlGvqeedgswsavklsrdhnaqneselerlkaehpkseaktvikedrllgll  120

         ntGdsra+lGvqeedgswsav+ls+dhnaqne+elerlk+ehpk+eak+v+k+drllgll

Q: 347   NTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKNEAKSVVKQDRLLGLL  406

         ************************************************************

S: 121   iplrafGdvkfkwskelqkrvvesgfdvladney.kfiapnyytppyltaepevtyhrlr  179

         +p+rafGdvkfkws++lqkrv+esg+d+l+dney kfi+pny+tppyltaepevtyhrlr

Q: 407   MPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYtKFIPPNYHTPPYLTAEPEVTYHRLR  466

         ************************************************************

S: 180   pqdkflvlasdGlwdllsredvvrlvgeylae  211

         pqdkflvla+dGlw++++r+dvvr+vgeyl+

Q: 467   PQDKFLVLATDGLWETMHRQDVVRIVGEYLTG  498

         *****************************875

Domain Sequence
(FASTA)

TDIDVKEALI NAFKRLDNDI SLEAQVGDPN SFLNYLVLRV AFSGATACVA HVDGVDLHVA 60

NTGDSRAMLG VQEEDGSWSA VTLSNDHNAQ NERELERLKL EHPKNEAKSV VKQDRLLGLL 120

MPFRAFGDVK FKWSIDLQKR VIESGPDQLN DNEYTKFIPP NYHTPPYLTA EPEVTYHRLR 180

PQDKFLVLAT DGLWETMHRQ DVVRIVGEYL TG 212

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005739	; C:mitochondrion
GO:0046872	; F:metal ion binding
GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0035970	; P:peptidyl-threonine dephosphorylation

KEGG

InterPros

IPR001932	; PP2C-like.
IPR000222	; PP2C_Mn2_Asp60_BS.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481

; PP2C; 1.

SMARTs

SM00331	; PP2C_SIG; 1.
SM00332	; PP2Cc; 1.

Prosites

PS01032

; PP2C; 1.

Prints

Created Date

20-Feb-2013