| Tag | Content |
|---|
| EKPD ID | EPS-ORC-00070 |
| Classification | | Group/Family | Score | E-Value | Start | End | Domain Length |
|---|
| PPP/PP2A | 419.6 | 1.7E-126 | 51 | 243 | 193 |
|
| Status | Reviewed |
| Ensembl Protein | ENSOCUP00000004530 |
| UniProt Accession | P11611; |
| Protein Name | Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform |
| Protein Synonyms/Alias | PP2A-beta; |
| Gene Name | PPP2CB |
| Gene Synonyms/Alias | PPP2CB; |
| Ensembl Information | |
| Organism | Oryctolagus cuniculus |
| Functional Description | PP2A can modulate the activity of phosphorylase B kinasecasein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. |
| Protein Length | 309 |
Protein Sequence
(FASTA) | | MDDKTFTKEL DQWVEQLNEC KQLNENQVRT LCEKAKEILT KESNVQEVRC PVTVCGDVHG 60 | | QFHDLMELFR IGGKSPDTNY LFMGDYVDRG YYSVETVTLL VALKVRYPER ITILRGNHES 120 | | RQITQVYGFY DECLRKYGNA NVWKYFTDLF DYLPLTALVD GQIFCLHGGL SPSIDTLDHI 180 | | RALDRLQEVP HEGPMCDLLW SDPDDRGGWG ISPRGAGYTF GQDISETFNH ANGLTLVSRA 240 | | HQLVMEGYNW CHDRNVVTIF SAPNYCYRCG NQAAIMELDD TLKYSFLQFD PAPRRGEPHV 300 | | TRRTPDYFL 309 |
|
Nucleotide Sequence
(FASTA) | | ATGGACGACA AGACGTTCAC CAAGGAGCTG GACCAGTGGG TCGAGCAGCT GAACGAGTGT 60 | | AAGCAGCTCA ACGAGAACCA AGTGCGGACG CTGTGCGAGA AGGCTAAGGA AATTTTAACA 120 | | AAAGAATCCA ATGTGCAAGA GGTTCGTTGT CCTGTTACCG TCTGTGGAGA TGTGCATGGT 180 | | CAATTCCATG ACCTTATGGA ACTCTTTAGA ATTGGTGGGA AATCACCAGA TACAAACTAT 240 | | CTATTCATGG GAGACTACGT GGACAGAGGT TATTACTCAG TGGAGACTGT GACTCTTCTT 300 | | GTAGCATTAA AGGTGCGTTA TCCAGAACGC ATTACAATAT TGAGAGGAAA TCATGAAAGC 360 | | CGACAAATTA CCCAAGTATA TGGCTTTTAT GATGAATGTC TACGGAAGTA TGGAAATGCC 420 | | AATGTGTGGA AATATTTTAC AGACCTATTT GATTATCTTC CACTTACAGC TTTGGTAGAT 480 | | GGACAGATAT TCTGCCTCCA TGGTGGCCTG TCTCCATCCA TAGATACACT GGATCATATA 540 | | AGAGCCCTGG ATCGTTTACA AGAAGTTCCA CACGAGGGCC CAATGTGTGA TCTGTTGTGG 600 | | TCTGATCCAG ATGATCGTGG TGGGTGGGGT ATTTCACCAC GTGGTGCCGG CTACACTTTT 660 | | GGACAAGACA TTTCTGAAAC ATTTAACCAC GCCAATGGTC TCACACTGGT CTCCCGTGCC 720 | | CACCAACTTG TGATGGAGGG ATACAACTGG TGTCATGACC GGAATGTGGT TACCATTTTC 780 | | AGTGCACCTA ATTACTGTTA TCGTTGTGGG AACCAGGCTG CTATCATGGA ATTAGATGAC 840 | | ACTTTAAAAT ATTCCTTCCT TCAGTTCGAT CCAGCACCTC GTCGTGGAGA GCCTCACGTA 900 | | ACCCGGCGCA CCCCAGACTA CTTCCTGTGA 930 |
|
| Domain Profile | S: 1 pvtvcgdvhgqfhdllelfriggkspdtnylflgdyvdrgyysvetvtllvalkvryrer 60 | pvtvcgdvhgqfhdl+elfriggkspdtnylf+gdyvdrgyysvetvtllvalkvry+er | Q: 51 PVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPER 110 | 9*********************************************************** |
| S: 61 itilrgnhesrqitqvygfydeclrkygnanvwkyftdlfdylpltalvdgkifclhggl 120 | itilrgnhesrqitqvygfydeclrkygnanvwkyftdlfdylpltalvdg+ifclhggl | Q: 111 ITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGL 170 | ************************************************************ |
| S: 121 spsidtldeiraldrlqevphegplcdllwsdpddregwgisprgagytfgqdiseqfnh 180 | spsidtld+iraldrlqevphegp+cdllwsdpddr+gwgisprgagytfgqdise+fnh | Q: 171 SPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNH 230 | ************************************************************ |
| S: 181 angleliarahql 193 | angl+l++rahql | Q: 231 ANGLTLVSRAHQL 243 | ************8 |
|
Domain Sequence
(FASTA) | | PVTVCGDVHG QFHDLMELFR IGGKSPDTNY LFMGDYVDRG YYSVETVTLL VALKVRYPER 60 | | ITILRGNHES RQITQVYGFY DECLRKYGNA NVWKYFTDLF DYLPLTALVD GQIFCLHGGL 120 | | SPSIDTLDHI RALDRLQEVP HEGPMCDLLW SDPDDRGGWG ISPRGAGYTF GQDISETFNH 180 | | ANGLTLVSRA HQL 193 |
|
| Keyword | Centromere; Chromosome; Complete proteome; Cytoplasm; Cytoskeleton; Hydrolase; Iron; Manganese; Metal-binding; Methylation; Nucleus; Phosphoprotein; Protein phosphatase; Reference proteome. |
| Sequence Source | Ensembl |
| Orthology | |
| Gene Ontology | |
| KEGG | |
| InterPros | |
| Pfam | |
| SMARTs | |
| Prosites | |
| Prints | |
| Created Date | 20-Feb-2013 |