EKS-ORC-00076

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORC-00076

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/GSK	449.1	7.3E-135	94	377	284

Status

Unreviewed

Ensembl Protein

ENSOCUP00000021591

UniProt Accession

G1SR14;

Protein Name

Protein Synonyms/Alias

Gene Name

ERF

Gene Synonyms/Alias

ERF;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOCUG00000006441	ENSOCUP00000005577	ENSOCUT00000006451
ENSOCUG00000006441	ENSOCUP00000024073	ENSOCUT00000029199
ENSOCUG00000006441	ENSOCUP00000005571	ENSOCUT00000006443
ENSOCUG00000006441	ENSOCUP00000022877	ENSOCUT00000028210
ENSOCUG00000006441	ENSOCUP00000021591	ENSOCUT00000028066

Organism

Oryctolagus cuniculus

Functional Description

Protein Length

433

Protein Sequence
(FASTA)

GGGGGGLMRT PGSCGEPKEA GRGRARRGAC GGGGGLLRAV GVQVSGGGGG AGGPRRGTSF 60

PPPGVKLGRD SGKVTTVVAT LGQGPERSQE VAYTDIKVIG NGSFGVVYQA RLAETRELVA 120

IKKVLQDKRF KNRELQIMRK LDHCNIVRLR YFFYSSGEKK DELYLNLVLE YVPETVYRVA 180

RHFTKAKLTI PIIYVKVYMY QLFRSLAYIH SQGVCHRDIK PQNLLVDPDT AVLKLCDFGS 240

AKQLVRGEPN VSYICSRYYR APELIFGATD YTSSIDVWSA GCVLAELLLG QPIFPGDSGV 300

DQLVEIIKVL GTPTREQIRE MNPNYTEFKF PQIKAHPWTK VFKSRTPPEA IALCSSLLEY 360

TPSSRLSPLE ACAHSFFDEL RCLGTQLPNN RPLPPLFNFS PAELSIQPSL NAILIPPHLR 420

SPAGSTPLSQ SSQ 433

Nucleotide Sequence
(FASTA)

GGCGGTGGTG GTGGGGGTCT CATGAGAACC CCTGGTTCCT GCGGGGAGCC TAAGGAGGCA 60

GGGCGGGGCC GGGCCAGGCG GGGAGCGTGT GGGGGTGGCG GGGGGCTGCT CCGGGCTGTG 120

GGAGTCCAGG TCTCTGGGGG TGGTGGAGGG GCCGGTGGGC CCCGGCGCGG CACTAGCTTC 180

CCGCCGCCGG GAGTGAAGCT GGGCCGTGAC AGCGGGAAGG TGACCACAGT GGTGGCCACG 240

CTGGGCCAAG GCCCAGAGCG CTCCCAGGAG GTGGCTTACA CAGACATCAA AGTGATTGGC 300

AATGGCTCTT TCGGGGTGGT GTACCAGGCA CGGCTGGCGG AGACCAGGGA GCTGGTGGCT 360

ATCAAGAAGG TTCTCCAGGA CAAGAGGTTC AAGAACCGAG AGCTGCAGAT TATGCGTAAG 420

CTGGACCACT GCAATATTGT GAGGCTGAGA TACTTCTTCT ACTCCAGTGG GGAGAAGAAG 480

GATGAGCTTT ACCTGAACCT GGTGCTGGAA TACGTGCCCG AGACAGTGTA CCGGGTGGCC 540

CGCCACTTCA CCAAGGCCAA ACTGACCATC CCTATCATCT ACGTGAAGGT GTACATGTAC 600

CAGCTGTTCC GGAGCCTGGC CTACATCCAC TCCCAGGGTG TGTGTCACCG TGACATCAAG 660

CCGCAGAACC TGCTGGTGGA CCCCGACACC GCTGTCCTCA AGCTTTGCGA TTTTGGCAGC 720

GCAAAGCAGT TGGTCCGCGG GGAGCCCAAC GTGTCCTACA TCTGTTCCCG CTACTACCGG 780

GCCCCAGAGC TCATCTTCGG AGCCACCGAT TACACCTCAT CCATTGATGT GTGGTCAGCT 840

GGCTGCGTGC TGGCTGAGCT CCTCCTCGGC CAGCCCATCT TCCCTGGGGA CAGTGGGGTG 900

GACCAGCTCG TGGAGATTAT CAAGGTGCTG GGAACACCAA CCCGGGAACA AATCCGAGAG 960

ATGAACCCCA ACTACACAGA GTTCAAGTTC CCCCAGATTA AAGCTCATCC CTGGACAAAG 1020

GTGTTCAAAT CTCGAACGCC GCCTGAGGCC ATCGCGCTCT GCTCCAGCCT GCTGGAGTAC 1080

ACGCCGTCCT CACGGCTCTC CCCGCTAGAG GCCTGCGCCC ACAGCTTCTT CGATGAACTG 1140

CGATGTCTCG GAACCCAGCT CCCCAACAAC CGCCCGCTCC CCCCTCTCTT CAACTTCAGT 1200

CCTGCCGAAC TCTCCATCCA GCCATCTCTC AATGCCATCC TCATCCCTCC TCACTTGAGG 1260

TCCCCGGCGG GCTCCACCCC TCTCTCCCAG TCCTCACAA 1299

Domain Profile

S: 2     eelkligsGsFgnVyqavlseesekevaiKkvlqdkklknlEleilrklkHknivrLlyf  61

         +++k+ig+GsFg+Vyqa+l+e++e  vaiKkvlqdk++kn+El+i+rkl+H+nivrL+yf

Q: 94    TDIKVIGNGSFGVVYQARLAETREL-VAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYF  152

         789**********************.**********************************

S: 62    fsksaekkdkvylnlvleylPetlakvlrelkdkkkkldvlevklytyQlfrglaylhsl  121

         f++s ekkd++ylnlvley+Pet+++v+r+++++k ++++++vk+y+yQlfr+lay+hs+

Q: 153   FYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPIIYVKVYMYQLFRSLAYIHSQ  212

         ************************************************************

S: 122   eivHrDiKPqNllvdeetgvlKlcDfGsakrleknepnvsYivsRyYRaPELllgakeyt  181

         +++HrDiKPqNllvd++t+vlKlcDfGsak+l+++epnvsYi+sRyYRaPEL++ga++yt

Q: 213   GVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYT  272

         ************************************************************

S: 182   tkiDvWsagcvlaEllkgkvlfkgksakdqlelivkvlGtptkedikemnvkykekkfkk  241

         ++iDvWsagcvlaEll+g+++f+g+s++dql++i+kvlGtpt+e+i+emn++y+e+kf++

Q: 273   SSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQ  332

         ************************************************************

S: 242   ikkvslakvlkkkedkeavdllkkilkyepkkRlsalellahpff  286

         ik+++++kv+k+++++ea++l++++l+y+p++Rls+le++ah+ff

Q: 333   IKAHPWTKVFKSRTPPEAIALCSSLLEYTPSSRLSPLEACAHSFF  377

         ********************************************9

Domain Sequence
(FASTA)

TDIKVIGNGS FGVVYQARLA ETRELVAIKK VLQDKRFKNR ELQIMRKLDH CNIVRLRYFF 60

YSSGEKKDEL YLNLVLEYVP ETVYRVARHF TKAKLTIPII YVKVYMYQLF RSLAYIHSQG 120

VCHRDIKPQN LLVDPDTAVL KLCDFGSAKQ LVRGEPNVSY ICSRYYRAPE LIFGATDYTS 180

SIDVWSAGCV LAELLLGQPI FPGDSGVDQL VEIIKVLGTP TREQIREMNP NYTEFKFPQI 240

KAHPWTKVFK SRTPPEAIAL CSSLLEYTPS SRLSPLEACA HSFF 284

Keyword

Complete proteome; DNA-binding; Nucleus; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0043565	; F:sequence-specific DNA binding
GO:0003700	; F:sequence-specific DNA binding transcription factor activity
GO:0003714	; F:transcription corepressor activity
GO:0000122	; P:negative regulation of transcription from RNA polymerase II promoter

KEGG

InterPros

IPR000418	; Ets.
IPR011991	; WHTH_trsnscrt_rep_DNA-bd.

Pfam

PF00178

; Ets; 1.

SMARTs

SM00413

; ETS; 1.

Prosites

PS00345	; ETS_DOMAIN_1; 1.
PS00346	; ETS_DOMAIN_2; 1.
PS50061	; ETS_DOMAIN_3; 1.

Prints

PR00454

; ETSDOMAIN.

Created Date

20-Feb-2013