EKS-ORC-00110

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORC-00110

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/NAK	364.0	5.4E-109	1	255	255

Status

Unreviewed

Ensembl Protein

ENSOCUP00000009959

UniProt Accession

G1T1J9;

Protein Name

Protein Synonyms/Alias

Gene Name

BMP2K

Gene Synonyms/Alias

BMP2K;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOCUG00000011578	ENSOCUP00000009959	ENSOCUT00000011581

Organism

Oryctolagus cuniculus

Functional Description

Protein Length

1081

Protein Sequence
(FASTA)

GGFSTVFLVR THGGIRCALK RMFVNNVPDL NICKREITIM KELSGHKNIV GYLDCAVNSI 60

SDNVWEVLIL MEYCRAGQVV NQMNKKLQTG FTEPEVLQIF CDTCEAVARL HQCKTPIIHR 120

DLKVENILLN DGGNYVLCDF GSATNKFLNP QKDGVNVVEE EIKKYTTLSY RAPEMINLYG 180

GKPITTKADI WWALGCLLYK LCFFTLPFGE SQVAICDGSF TIPDNSRYSH HIHCLIRFML 240

EPDPERRPDI FQVSYFAFKF AKKDCPVSNI NNSPIPSALP EPMTASEAAA RKSQIKARIT 300

DTIGPTETSI APRQRPKANS ATATPSVLTI QSSATPVKVP VPGEFDNHRP KGALRPGNGP 360

EVLLGQALPQ QPSQPPPQQH RVLQQLQQGD WRLQQLHLQP RGAHQQPQHH QLLQDAYMQQ 420

YQHAMQQQQM LQQQFLMHSA SQPQPSASQY PAMVQQYQQA FLQQQMLAQH QQSQQQASPE 480

YLTSPQEFSP ALVTYPSSHP AQLATTVDSS YSASRSVADK EAVTNFTNQK NVSNPLDMSG 540

WNPFGEDNFS KLTEEELLDR EFDLLRSNRL EERASSDKNV DPLSAPHNHP PEDPFGSVPF 600

ISHSGSPEKR VEYSSMNLEH STANPIRNGK ASLVCKDQRT GKKSSENSSL QGQVQKGNDE 660

SESDFESDPP SPKSSEEEEQ EDEEVQGEQG DFNDEDTEPE NLGHRPLLMD SEDEEEEEKH 720

SSDSDYEQTK AKYSGESLVC KDKPGGGPTQ GLATALLTPT PLPSRFGLET PKQEFDVFGA 780

VPFFAVHAQP PQPGDNAKNL GQQRSPTVGL EQEEFDVFTK APFSKKVDVQ QRHVPAPQAH 840

TPPGCPQSVD VFGSTPFQPF PTSTSKSEST EDLFGLVPFE EVTGSQQQKV KQRSLQKLSS 900

RQRRTKQDMS KSNGKRHHGT PTSTKKTLKP TYRTPERARR HKKVGRRDSQ SSNEFLTISD 960

SKENISVALP DGKERGNVLQ PEESLLDPFG AKPFHPPDLP WHPSHQGLGD ICADHTTILP 1020

GRPRQNSLHG SFHSAEALKM DDFGAVPFTE LVVQSISPHQ SQQSQPVELD PFGAAPFPSK 1080

Q 1081

Nucleotide Sequence
(FASTA)

GGTGGATTCT CCACAGTTTT CCTTGTGCGA ACTCATGGTG GAATCCGATG TGCATTGAAG 60

CGAATGTTTG TCAATAACGT GCCAGACCTC AACATTTGTA AAAGGGAAAT TACAATAATG 120

AAAGAGTTAT CTGGTCACAA AAATATCGTG GGTTATTTGG ACTGTGCTGT TAATTCAATT 180

AGTGATAATG TATGGGAAGT GCTTATCTTA ATGGAGTATT GTCGAGCTGG GCAGGTAGTT 240

AATCAGATGA ATAAGAAGCT GCAGACGGGT TTTACGGAAC CAGAAGTGTT ACAGATATTC 300

TGTGATACCT GTGAGGCTGT TGCAAGGCTG CATCAGTGTA AGACTCCGAT AATTCATCGG 360

GATCTAAAGG TAGAAAATAT TTTGTTGAAT GATGGCGGAA ACTATGTGCT TTGTGACTTT 420

GGCAGTGCCA CTAATAAATT TCTTAATCCT CAAAAAGATG GAGTTAATGT AGTAGAAGAA 480

GAAATTAAAA AGTATACAAC TCTGTCATAC AGAGCCCCTG AAATGATCAA CCTTTATGGA 540

GGGAAACCCA TCACTACCAA GGCTGATATC TGGTGGGCCC TGGGATGTTT ACTCTATAAA 600

CTCTGTTTCT TCACTCTTCC TTTTGGTGAG AGTCAGGTTG CCATCTGTGA TGGCAGCTTC 660

ACCATCCCAG ACAATTCTCG CTACTCTCAT CACATACATT GCCTAATAAG ATTCATGCTT 720

GAACCAGATC CAGAACGTAG ACCGGATATT TTTCAGGTGT CATATTTTGC ATTTAAATTT 780

GCCAAAAAGG ATTGTCCAGT CTCCAACATC AATAATTCTC CTATTCCTTC AGCTCTTCCT 840

GAACCGATGA CTGCTAGTGA AGCCGCTGCT AGGAAAAGCC AAATAAAAGC CAGAATAACA 900

GATACCATTG GACCAACAGA AACCTCAATT GCACCTAGAC AAAGACCAAA GGCCAACTCC 960

GCTACTGCCA CTCCCAGCGT GCTGACCATT CAAAGTTCAG CAACACCTGT TAAAGTCCCA 1020

GTTCCTGGTG AATTCGATAA CCACAGACCA AAAGGAGCAC TAAGACCTGG AAATGGCCCT 1080

GAGGTTTTAC TGGGCCAGGC CCTGCCTCAG CAGCCTTCGC AGCCGCCGCC ACAGCAGCAC 1140

AGAGTCCTTC AGCAACTACA GCAGGGAGAC TGGAGGTTAC AGCAGCTGCA TCTACAGCCA 1200

CGCGGGGCGC ACCAGCAGCC ACAGCACCAT CAGCTACTTC AGGATGCTTA TATGCAGCAG 1260

TATCAACATG CAATGCAGCA GCAGCAGATG CTTCAACAAC AGTTTTTAAT GCATTCAGCC 1320

TCTCAGCCGC AGCCTTCTGC ATCACAGTAT CCTGCGATGG TGCAGCAATA TCAGCAGGCT 1380

TTCTTGCAGC AGCAGATGCT GGCTCAGCAC CAGCAGTCTC AGCAACAGGC GTCACCCGAG 1440

TACCTCACCT CCCCTCAAGA GTTCTCACCA GCCTTAGTCA CCTACCCTTC CTCACATCCA 1500

GCTCAGCTTG CAACCACAGT GGACTCCTCT TACAGTGCCA GTAGGTCAGT TGCTGATAAA 1560

GAGGCAGTCA CAAATTTTAC AAATCAGAAG AACGTCAGTA ACCCACTGGA TATGTCAGGG 1620

TGGAATCCTT TTGGAGAGGA TAATTTCTCC AAGTTAACTG AAGAGGAACT ATTGGACAGA 1680

GAATTTGACC TTCTGAGATC AAACAGGCTC GAGGAGAGAG CATCCTCAGA TAAGAATGTA 1740

GACCCACTGT CTGCTCCACA TAACCATCCT CCAGAAGATC CTTTTGGTTC TGTTCCTTTC 1800

ATTTCTCATT CAGGTTCTCC CGAAAAGAGA GTTGAATATT CATCCATGAA TCTAGAACAT 1860

AGCACTGCAA ACCCCATCAG GAATGGAAAA GCAAGTCTGG TATGTAAAGA TCAGCGGACC 1920

GGAAAGAAAA GCTCAGAGAA TTCATCATTA CAGGGTCAAG TGCAAAAGGG GAATGATGAA 1980

TCTGAAAGTG ATTTTGAATC AGATCCCCCT TCTCCTAAGA GCAGTGAAGA GGAAGAACAA 2040

GAGGATGAAG AAGTTCAGGG AGAGCAAGGG GATTTTAATG ATGAGGATAC TGAACCAGAA 2100

AACCTGGGCC ATCGGCCTCT GCTTATGGAT TCTGAGGATG AGGAAGAAGA GGAGAAACAC 2160

AGCTCTGATT CTGATTATGA GCAGACTAAA GCAAAGTACA GTGGGGAGAG CCTTGTCTGC 2220

AAAGACAAAC CTGGCGGTGG ACCAACTCAA GGCCTGGCCA CAGCACTCCT CACCCCCACC 2280

CCGCTGCCCT CTAGGTTTGG GTTGGAGACT CCCAAACAGG AGTTTGACGT ATTTGGCGCT 2340

GTCCCCTTCT TTGCAGTGCA TGCTCAACCG CCCCAGCCGG GAGACAACGC AAAGAACCTG 2400

GGTCAACAGA GGTCTCCCAC TGTGGGACTA GAGCAGGAGG AATTTGATGT GTTCACGAAG 2460

GCTCCCTTTA GCAAGAAGGT CGATGTGCAG CAGCGCCACG TGCCGGCGCC CCAGGCCCAC 2520

ACTCCCCCTG GCTGCCCCCA GAGCGTAGAT GTCTTTGGCT CCACTCCATT TCAGCCCTTT 2580

CCCACATCAA CAAGTAAAAG TGAAAGCACC GAGGACCTTT TTGGCCTTGT GCCCTTTGAG 2640

GAAGTAACTG GGAGTCAGCA GCAAAAAGTC AAACAGCGCA GCTTACAGAA ACTGTCCTCT 2700

CGCCAAAGGC GCACAAAGCA GGATATGTCC AAGAGTAACG GGAAGCGGCA TCATGGCACG 2760

CCGACCAGCA CCAAGAAGAC CCTGAAGCCT ACCTACCGCA CTCCAGAGAG GGCTCGCAGG 2820

CACAAGAAAG TGGGCCGCCG AGACTCTCAG AGCAGCAATG AATTTCTAAC CATCTCGGAC 2880

TCCAAGGAGA ACATCAGCGT GGCCCTGCCT GATGGGAAGG AGAGGGGGAA TGTCTTACAG 2940

CCCGAGGAGA GTCTGTTGGA CCCCTTTGGA GCCAAGCCCT TCCATCCTCC AGACCTGCCC 3000

TGGCACCCGT CCCATCAGGG CCTGGGCGAC ATCTGTGCCG ACCACACCAC CATCCTGCCC 3060

GGGCGGCCAC GACAGAATTC ACTCCATGGG TCATTCCACA GTGCGGAGGC ATTGAAAATG 3120

GATGACTTTG GTGCGGTGCC CTTTACAGAA CTCGTGGTGC AAAGCATCAG TCCACATCAG 3180

TCCCAGCAGT CCCAGCCAGT TGAATTAGAC CCATTCGGTG CTGCTCCATT TCCTTCTAAA 3240

CAGTAG 3246

Domain Profile

S: 10    GGfalvylaedastgekyalKrilvneeedleeikrEieimkklsghknivklvdssvke  69

         GGf++v+l++ ++ g ++alKr++vn++ dl+ +krEi+imk+lsghkniv ++d++v++

Q: 1     GGFSTVFLVR-THGGIRCALKRMFVNNVPDLNICKREITIMKELSGHKNIVGYLDCAVNS  59

         9*********.9999*********************************************

S: 70    ekdngskevlllleyckkgslvdllnkrlekgelseaeilkilldvtravaalHalsvpl  129

          +d +++evl+l+eyc++g++v+++nk+l++g ++e e+l+i++d+++ava+lH++++p+

Q: 60    ISD-NVWEVLILMEYCRAGQVVNQMNKKLQTG-FTEPEVLQIFCDTCEAVARLHQCKTPI  117

         ***.7**************************9.***************************

S: 130   iHRDlkveNillsdegelvlcDlGSattaileveskqelsalqeeieknttlsyrsPEli  189

         iHRDlkveNill+d g++vlcD+GSat+++l+++ k+++++++eei+k+ttlsyr+PE+i

Q: 118   IHRDLKVENILLNDGGNYVLCDFGSATNKFLNPQ-KDGVNVVEEEIKKYTTLSYRAPEMI  176

         **********************************.*************************

S: 190   dlysnlvideksDi.WaLGcllYklcffesPfeesvklailngkysiPensryseklksl  248

         +ly +++i++k+Di WaLGcllYklcff+ Pf+es ++ai++g+++iP+nsrys+++++l

Q: 177   NLYGGKPITTKADIwWALGCLLYKLCFFTLPFGES-QVAICDGSFTIPDNSRYSHHIHCL  235

         **************55*******************.************************

S: 249   ikkmlevdpeeRptiaqvle  268

         i+ mle+dpe+Rp+i+qv++

Q: 236   IRFMLEPDPERRPDIFQVSY  255

         ******************87

Domain Sequence
(FASTA)

GGFSTVFLVR THGGIRCALK RMFVNNVPDL NICKREITIM KELSGHKNIV GYLDCAVNSI 60

SDNVWEVLIL MEYCRAGQVV NQMNKKLQTG FTEPEVLQIF CDTCEAVARL HQCKTPIIHR 120

DLKVENILLN DGGNYVLCDF GSATNKFLNP QKDGVNVVEE EIKKYTTLSY RAPEMINLYG 180

GKPITTKADI WWALGCLLYK LCFFTLPFGE SQVAICDGSF TIPDNSRYSH HIHCLIRFML 240

EPDPERRPDI FQVSY 255

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0019208	; F:phosphatase regulator activity
GO:0004674	; F:protein serine/threonine kinase activity
GO:0030500	; P:regulation of bone mineralization

KEGG

InterPros

IPR026105	; BMP-2-ind_kinase.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013