EKS-ORC-00134

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORC-00134

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/RIO	335.7	1.4E-100	181	397	217

Status

Unreviewed

Ensembl Protein

ENSOCUP00000010168

UniProt Accession

G1T225;

Protein Name

Serine/threonine-protein kinase RIO1

Protein Synonyms/Alias

Gene Name

RIOK1

Gene Synonyms/Alias

RIOK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOCUG00000011824	ENSOCUP00000010168	ENSOCUT00000011829

Organism

Oryctolagus cuniculus

Functional Description

Protein Length

568

Protein Sequence
(FASTA)

MDYRRVLMGR VVPGQFDDAD SDSENPDLKT VKGEGGALSE DFEGHVVAEK GEGELEDEED 60

EDFDEDDSDW EWDDGVGRLT RGNGWSGGNN PQANRQTAHC TAAKMSTPAD KVLRKFENKI 120

NLDKLYVTDA VINKVTEKSR QKEADLYRIK DKADRATVEQ VLDPRTRMIL FKMLTRGIIS 180

EINGCISTGK EANVYHASTA NGESRAIKIY KTSILVFKDR DKYVSGEFRF RHGYCKGNPR 240

KMVKTWAEKE MRNLIRLNTA EIPCPEPVML RSHVLVMGFI GKDDMPAPLL KNVQLSESKA 300

RELYLQVIQY MRRMYQDARL VHADLSEFNM LYHAGDVYII DVSQSVEHDH PHALEFLRKD 360

CANVSDFFLK HSVAVMTVRE LFEFVTDPSI TRENMDAYLS KAMELASQRT REERSNQDHV 420

DEEVFKRAYI PRTLNEVKNY ERDVDIMMKL KEEDMALNAQ QDNILYQTVT GLKKDLSGVQ 480

EVPALLENQV QDKTYSDSEG AGSSECSDTD SEEQGDHAHC KKHTTDPDVD KKERKKKVKE 540

AQREKRKNKI PKHVKKRREK TAKTKRGK 568

Nucleotide Sequence
(FASTA)

ATGGACTACC GGCGGGTCCT GATGGGCCGG GTGGTGCCCG GCCAGTTCGA CGACGCGGAC 60

TCCGACAGTG AGAACCCAGA CTTGAAGACA GTCAAAGGGG AAGGTGGCGC TCTGTCTGAA 120

GACTTTGAAG GTCATGTGGT TGCGGAGAAG GGCGAAGGTG AGCTAGAAGA TGAAGAGGAC 180

GAGGACTTTG ATGAAGACGA CAGTGACTGG GAATGGGATG ATGGAGTGGG CCGGCTCACC 240

AGGGGAAATG GCTGGAGTGG CGGGAACAAC CCACAGGCAA ATCGACAGAC TGCCCATTGC 300

ACTGCAGCCA AAATGTCTAC TCCAGCTGAC AAAGTCTTAC GGAAATTTGA GAATAAAATT 360

AATTTAGATA AGCTGTATGT TACTGACGCT GTCATAAATA AAGTCACTGA GAAGTCTAGA 420

CAGAAGGAAG CAGATCTGTA TCGCATCAAG GATAAGGCAG ACAGAGCGAC AGTAGAACAG 480

GTTTTGGATC CCAGAACAAG AATGATTTTA TTCAAGATGT TGACCAGAGG GATCATATCA 540

GAGATTAATG GCTGTATTAG CACAGGAAAA GAAGCTAATG TATACCATGC TAGCACAGCA 600

AATGGAGAGA GCAGAGCAAT CAAAATCTAT AAAACTTCCA TTTTGGTGTT CAAAGATCGG 660

GATAAATATG TAAGTGGGGA ATTCAGATTT CGTCATGGCT ATTGTAAAGG AAACCCTCGA 720

AAAATGGTGA AAACCTGGGC AGAAAAAGAA ATGAGGAACT TAATCAGGTT AAACACAGCG 780

GAGATACCGT GTCCAGAACC AGTCATGCTG AGAAGTCATG TTCTCGTCAT GGGTTTCATT 840

GGTAAAGACG ACATGCCAGC GCCACTCCTG AAGAACGTCC AGCTATCTGA ATCCAAGGCC 900

CGCGAGCTGT ATCTGCAGGT CATTCAGTAC ATGCGGAGGA TGTATCAGGA TGCCAGACTT 960

GTTCATGCCG ATCTCAGTGA ATTTAACATG CTGTACCACG CTGGGGACGT GTACATCATC 1020

GATGTGTCTC AGTCTGTGGA GCACGACCAC CCGCATGCCC TGGAGTTCCT GAGGAAAGAC 1080

TGTGCCAACG TCAGCGATTT CTTTTTGAAG CACAGCGTCG CTGTCATGAC TGTGCGGGAG 1140

CTCTTTGAAT TTGTCACAGA CCCATCCATC ACACGTGAGA ACATGGATGC TTATCTCTCA 1200

AAGGCCATGG AACTAGCATC TCAAAGGACC AGAGAAGAAA GGTCTAACCA AGACCATGTG 1260

GATGAAGAGG TGTTTAAGCG GGCATATATT CCTAGAACCC TGAATGAAGT AAAAAACTAC 1320

GAGAGAGATG TGGACATAAT GATGAAATTG AAGGAAGAGG ACATGGCCTT GAATGCTCAG 1380

CAGGATAATA TCCTGTACCA GACCGTCACA GGGTTGAAGA AGGACCTGTC AGGCGTGCAG 1440

GAGGTCCCTG CTCTGCTAGA AAACCAAGTT CAGGACAAGA CTTACTCTGA CTCAGAAGGA 1500

GCCGGCAGCT CTGAGTGCTC CGACACAGAC TCTGAAGAGC AGGGCGACCA CGCCCACTGC 1560

AAGAAACACA CCACCGACCC TGATGTTGAT AAAAAGGAAA GAAAAAAGAA GGTCAAGGAA 1620

GCCCAGAGAG AGAAAAGAAA AAACAAAATT CCTAAACATG TAAAGAAAAG GAGGGAGAAG 1680

ACGGCCAAGA CCAAAAGGGG CAAATAG 1707

Domain Profile

S: 2     svgntigvgkesdvykvsekngeeraiKiyktsllvlknrdkYvdgefrfkksrskanpr  61

         +++++i++gke++vy++s++nge+raiKiykts+lv+k+rdkYv+gefrf+++++k npr

Q: 181   EINGCISTGKEANVYHASTANGESRAIKIYKTSILVFKDRDKYVSGEFRFRHGYCKGNPR  240

         699*********************************************************

S: 62    klsrlwAeKEfrnlkrlyekgvpvPepidlkrhvlvmeligrdgypapklkdvklkeeei  121

         k++++wAeKE+rnl+rl+++++p+Pep++l++hvlvm +ig+d++pap lk+v+l+e+++

Q: 241   KMVKTWAEKEMRNLIRLNTAEIPCPEPVMLRSHVLVMGFIGKDDMPAPLLKNVQLSESKA  300

         ************************************************************

S: 122   kelYsdllalivklynegrLvHaDlsEfnilleddklvliDvsqsveieHpdaleflrrD  181

         +elY +++++++++y+++rLvHaDlsEfn+l++++++++iDvsqsve++Hp+aleflr+D

Q: 301   RELYLQVIQYMRRMYQDARLVHADLSEFNMLYHAGDVYIIDVSQSVEHDHPHALEFLRKD  360

         ************************************************************

S: 182   vknvkefFkkklvydvlrerelfelvsasgltkekead  219

         ++nv++fF k++v +v+++relfe+v++ ++t+e+++

Q: 361   CANVSDFFLKHSV-AVMTVRELFEFVTDPSITRENMDA  397

         *************.********************9985

Domain Sequence
(FASTA)

EINGCISTGK EANVYHASTA NGESRAIKIY KTSILVFKDR DKYVSGEFRF RHGYCKGNPR 60

KMVKTWAEKE MRNLIRLNTA EIPCPEPVML RSHVLVMGFI GKDDMPAPLL KNVQLSESKA 120

RELYLQVIQY MRRMYQDARL VHADLSEFNM LYHAGDVYII DVSQSVEHDH PHALEFLRKD 180

CANVSDFFLK HSVAVMTVRE LFEFVTDPSI TRENMDA 217

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>