EKS-ORC-00449

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORC-00449

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMK2	570.2	6.4E-172	2	252	251

Status

Unreviewed

Ensembl Protein

ENSOCUP00000023011

UniProt Accession

G1T3M7;

Protein Name

Protein Synonyms/Alias

Gene Name

CAMK2G

Gene Synonyms/Alias

CAMK2G;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOCUG00000012578	ENSOCUP00000023011	ENSOCUT00000023813
ENSOCUG00000012578	ENSOCUP00000021289	ENSOCUT00000030294
ENSOCUG00000012578	ENSOCUP00000010833	ENSOCUT00000012582
ENSOCUG00000012578	ENSOCUP00000017703	ENSOCUT00000024086

Organism

Oryctolagus cuniculus

Functional Description

Protein Length

509

Protein Sequence
(FASTA)

SRGAFSVVRR CVKKTSTQEY AAKIINTKKL SARDHQKLER EARICRLLKH PNIVRLHDSI 60

SEEGFHYLVF DLVTGGELFE DIVAREYYSE ADASHCIHQI LESVNHIHQH DIVHRDLKPE 120

NLLLASKCKG AAVKLADFGL AIEVQGEQQA WFGFAGTPGY LSPEVLRKDP YGKPVDIWAC 180

GVILYILLVG YPPFWDEDQH KLYQQIKAGA YDFPSPEWDT VTPEAKNLIN QMLTINPAKR 240

ITADQALKHP WVCQRATVAS MMHRQETVEC LRKFNARRKL KGAILTTMLV SRNFSAAKSL 300

LNKKSDGGVK KRKSSSSVHL MPQSNNKNSL VSPAQEPAPL QTAMEPQTTV VHNATDGIKG 360

STESCNTTTE DEDLKVRKQE IIKITEQLIE AINNGDFEAY TKICDPGLTS FEPEALGNLV 420

EGMDFHKFYF ENLLSKNSKP IHTTILNPHV HVIGEDAACI AYIRLTQYID GQGRPRTSQS 480

EETRVWHRRD GKWLNVHYHC SGAPAAPLQ 509

Nucleotide Sequence
(FASTA)

TCCAGGGGTG CTTTCTCTGT GGTCCGCAGG TGTGTGAAGA AAACCTCCAC GCAAGAGTAT 60

GCAGCAAAAA TCATCAATAC CAAGAAGTTG TCTGCCCGAG ATCACCAGAA GCTAGAACGT 120

GAGGCCCGGA TATGCCGACT TCTGAAACAC CCAAACATCG TGCGCCTCCA TGACAGTATT 180

TCTGAAGAAG GGTTTCACTA CCTCGTGTTC GACCTCGTCA CTGGAGGGGA GCTGTTTGAA 240

GACATTGTGG CCAGAGAGTA CTACAGCGAG GCAGACGCCA GCCACTGTAT ACACCAGATT 300

CTGGAGAGTG TTAACCACAT TCACCAGCAT GACATTGTAC ACAGGGACCT GAAGCCTGAG 360

AACTTGCTGC TGGCGAGTAA ATGCAAGGGT GCCGCCGTCA AGCTGGCTGA CTTTGGCCTC 420

GCCATCGAAG TACAGGGAGA GCAGCAGGCT TGGTTTGGTT TTGCTGGCAC CCCAGGTTAC 480

TTGTCCCCTG AGGTCTTGAG GAAAGATCCG TATGGAAAAC CTGTGGATAT CTGGGCTTGC 540

GGGGTCATCC TGTATATCCT CCTGGTGGGA TACCCTCCCT TCTGGGATGA GGATCAGCAC 600

AAGCTGTATC AGCAGATCAA GGCTGGAGCC TATGATTTCC CATCGCCAGA ATGGGATACG 660

GTGACTCCTG AAGCCAAGAA CTTGATCAAC CAGATGTTGA CCATAAACCC GGCAAAGCGC 720

ATCACGGCTG ACCAGGCTCT CAAGCACCCA TGGGTCTGCC AACGAGCCAC GGTGGCTTCC 780

ATGATGCATC GCCAGGAGAC CGTGGAGTGC TTGCGCAAGT TCAATGCCCG GAGGAAACTG 840

AAGGGTGCCA TCCTCACGAC CATGCTGGTC TCCAGGAACT TCTCAGCTGC CAAAAGCCTA 900

TTGAACAAGA AGTCGGATGG TGGTGTCAAG AAAAGGAAGT CGAGTTCCAG CGTGCACCTA 960

ATGCCACAGA GCAACAACAA AAACAGTCTC GTAAGCCCAG CCCAAGAGCC CGCGCCCTTG 1020

CAGACGGCCA TGGAGCCACA AACTACCGTG GTGCACAACG CTACAGATGG GATCAAGGGC 1080

TCCACAGAGA GCTGCAACAC CACTACAGAA GATGAGGACC TCAAAGTGCG AAAACAGGAG 1140

ATCATTAAGA TCACAGAACA GCTGATTGAA GCCATCAACA ATGGGGACTT TGAGGCCTAC 1200

ACGAAGATTT GTGATCCGGG CCTCACTTCC TTTGAGCCGG AGGCCCTTGG TAACCTCGTG 1260

GAGGGGATGG ATTTCCATAA GTTTTACTTT GAGAATCTCC TGTCCAAGAA CAGCAAGCCC 1320

ATCCATACCA CCATCCTAAA CCCACATGTC CACGTGATCG GAGAGGACGC AGCTTGCATC 1380

GCCTACATCC GCCTCACCCA GTACATCGAC GGGCAGGGTC GGCCCCGCAC CAGCCAGTCG 1440

GAGGAGACCC GGGTCTGGCA CCGCCGGGAT GGCAAGTGGC TCAATGTCCA CTACCACTGC 1500

TCAGGGGCCC CTGCCGCACC GCTGCAGTGA 1530

Domain Profile

S: 9     kgafsvvrrcvkvttgqeyaakiintkklsardhqklerearicrllkhpnivrlhdsis  68

         +gafsvvrrcvk+t++qeyaakiintkklsardhqklerearicrllkhpnivrlhdsis

Q: 2     RGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSIS  61

         79**********************************************************

S: 69    eegfhylvfdlvtggelfedivareyyseadashciqqilesvlhihqngvvhrdlkpen  128

         eegfhylvfdlvtggelfedivareyyseadashci+qilesv+hihq+++vhrdlkpen

Q: 62    EEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPEN  121

         ************************************************************

S: 129   lllaskakgaavkladfglaievqgdqqawfgfagtpgylspevlrkdpygkpvdlwacg  188

         lllask+kgaavkladfglaievqg+qqawfgfagtpgylspevlrkdpygkpvd+wacg

Q: 122   LLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACG  181

         ************************************************************

S: 189   vilyillvgyppfwdedqhrlyqqikagaydfpspewdtvtpeakdlinkmltinpakri  248

         vilyillvgyppfwdedqh+lyqqikagaydfpspewdtvtpeak+lin+mltinpakri

Q: 182   VILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRI  241

         ************************************************************

S: 249   tadealkhpwi  259

         tad+alkhpw+

Q: 242   TADQALKHPWV  252

         **********8

Domain Sequence
(FASTA)

RGAFSVVRRC VKKTSTQEYA AKIINTKKLS ARDHQKLERE ARICRLLKHP NIVRLHDSIS 60

EEGFHYLVFD LVTGGELFED IVAREYYSEA DASHCIHQIL ESVNHIHQHD IVHRDLKPEN 120

LLLASKCKGA AVKLADFGLA IEVQGEQQAW FGFAGTPGYL SPEVLRKDPY GKPVDIWACG 180

VILYILLVGY PPFWDEDQHK LYQQIKAGAY DFPSPEWDTV TPEAKNLINQ MLTINPAKRI 240

TADQALKHPW V 251

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004683	; F:calmodulin-dependent protein kinase activity
GO:0006816	; P:calcium ion transport
GO:0000082	; P:G1/S transition of mitotic cell cycle
GO:0046777	; P:protein autophosphorylation

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR013543	; Ca/CaM-dep_prot_kinase-assoc.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF08332	; CaMKII_AD; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013