EKS-ORC-00167

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORC-00167

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/PKA	483.3	1.7E-145	44	298	255

Status

Unreviewed

Ensembl Protein

ENSOCUP00000003134

UniProt Accession

G1TKB4;

Protein Name

Protein Synonyms/Alias

Gene Name

PRKACB

Gene Synonyms/Alias

PRKACB;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOCUG00000012937	ENSOCUP00000017399	ENSOCUT00000027650
ENSOCUG00000012937	ENSOCUP00000003134	ENSOCUT00000003613
ENSOCUG00000012937	ENSOCUP00000011140	ENSOCUT00000012940

Organism

Oryctolagus cuniculus

Functional Description

Protein Length

351

Protein Sequence
(FASTA)

MGNAATAKKG SEVESVKEFL AKAKEDFLKK WENPPPNNAG LEDFERKKTL GTGSFGRVML 60

VKHKATEQYY AMKILDKQKV VKLKQIEHTL NEKRILQAVN FPFLVRLEYS FKDNSNLYMV 120

MEYVPGGEMF SHLRRIGRFS EPHARFYAAQ IVLTFEYLHS LDLIYRDLKP ENLLIDHQGY 180

IQVTDFGFAK RVKGRTWTLC GTPEYLAPEI ILSKGYNKAV DWWALGVLIY EMAAGYPPFF 240

ADQPIQIYEK IVSGKVRFPS HFSSDLKDLL RNLLQVDLTK RFGNLKNGVS DIKTHKWFAT 300

TDWIAIYQRK VEAPFIPKFR GSGDTSNFDD YEEEDIRVSI TEKCAKEFCE F 351

Nucleotide Sequence
(FASTA)

ATGGGGAACG CGGCGACCGC CAAGAAAGGC AGCGAGGTGG AGAGCGTGAA AGAATTTCTA 60

GCCAAAGCCA AAGAAGACTT TTTGAAAAAA TGGGAGAATC CTCCTCCGAA TAATGCCGGA 120

CTTGAGGATT TTGAAAGGAA AAAGACCCTT GGAACGGGTT CATTTGGAAG AGTCATGCTG 180

GTGAAACATA AAGCCACTGA ACAGTATTAT GCTATGAAGA TCTTAGATAA GCAGAAGGTT 240

GTTAAACTGA AGCAAATAGA ACATACCCTG AATGAGAAAA GAATATTACA GGCAGTGAAT 300

TTTCCTTTTC TTGTTCGACT GGAATATTCT TTTAAGGATA ATTCTAATTT ATACATGGTT 360

ATGGAATATG TTCCTGGGGG TGAAATGTTT TCACATCTAA GAAGAATTGG AAGGTTCAGT 420

GAACCCCATG CACGGTTCTA TGCAGCTCAG ATAGTGCTAA CATTCGAGTA CCTCCATTCA 480

CTAGACCTCA TCTACAGAGA TCTAAAACCA GAAAATCTCT TAATTGACCA TCAAGGTTAT 540

ATCCAGGTCA CAGACTTTGG GTTTGCCAAA AGAGTTAAAG GCAGAACTTG GACATTATGT 600

GGCACCCCAG AATATTTGGC TCCAGAAATA ATCCTGAGCA AGGGCTACAA TAAGGCAGTG 660

GATTGGTGGG CATTAGGAGT GCTAATCTAT GAAATGGCAG CTGGCTACCC CCCATTCTTT 720

GCAGACCAAC CAATTCAGAT TTATGAAAAG ATCGTTTCTG GAAAAGTCCG ATTCCCATCC 780

CACTTCAGTT CAGATCTCAA AGATCTTCTA AGGAACCTAC TGCAAGTGGA TTTGACGAAA 840

CGATTTGGAA ATCTAAAGAA TGGTGTGAGT GACATAAAAA CTCACAAATG GTTTGCCACA 900

ACAGATTGGA TTGCTATTTA CCAGAGGAAG GTTGAAGCTC CATTCATACC AAAGTTCAGA 960

GGCTCTGGAG ATACCAGCAA CTTTGATGAC TATGAAGAAG AAGATATCCG TGTCTCTATA 1020

ACAGAAAAAT GTGCGAAAGA ATTTTGTGAA TTT 1053

Domain Profile

S: 1     ferlktlGtGsfGrvelvrekeskkyyalkvlskekvvklkqvehvknekrvlkavefpf  60

         fer+ktlGtGsfGrv+lv++k++++yya+k+l+k+kvvklkq+eh+ nekr+l+av+fpf

Q: 44    FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF  103

         799*********************************************************

S: 61    lvkllasfkdesnlylvleyveGGelfsylrkvrrfsekaarfyaaeivlaleylhsldl  120

         lv+l++sfkd+snly+v+eyv+GGe+fs+lr+++rfse++arfyaa+ivl++eylhsldl

Q: 104   LVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL  163

         ************************************************************

S: 121   iyrdlkpenllldkeGyikvtdfGfakkvkdrtwtlcGtpeylapeiiqskgynkavdww  180

         iyrdlkpenll+d++Gyi+vtdfGfak+vk+rtwtlcGtpeylapeii skgynkavdww

Q: 164   IYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWW  223

         ************************************************************

S: 181   alGvliyellaGyppffddqpikiyekivsgklkfpsklssdlkdllkkllqvdltkrlg  240

         alGvliye++aGyppff+dqpi+iyekivsgk++fps++ssdlkdll++llqvdltkr+g

Q: 224   ALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFG  283

         ************************************************************

S: 241   nlkngvedikehkwf  255

         nlkngv+dik+hkwf

Q: 284   NLKNGVSDIKTHKWF  298

         **************9

Domain Sequence
(FASTA)

FERKKTLGTG SFGRVMLVKH KATEQYYAMK ILDKQKVVKL KQIEHTLNEK RILQAVNFPF 60

LVRLEYSFKD NSNLYMVMEY VPGGEMFSHL RRIGRFSEPH ARFYAAQIVL TFEYLHSLDL 120

IYRDLKPENL LIDHQGYIQV TDFGFAKRVK GRTWTLCGTP EYLAPEIILS KGYNKAVDWW 180

ALGVLIYEMA AGYPPFFADQ PIQIYEKIVS GKVRFPSHFS SDLKDLLRNL LQVDLTKRFG 240

NLKNGVSDIK THKWF 255

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>