EKS-ORC-00183

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORC-00183

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/RCK	437.3	2.7E-131	4	285	282

Status

Unreviewed

Ensembl Protein

ENSOCUP00000011931

UniProt Accession

G1T6A4;

Protein Name

Protein Synonyms/Alias

Gene Name

MOK

Gene Synonyms/Alias

MOK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOCUG00000013870	ENSOCUP00000011931	ENSOCUT00000013872

Organism

Oryctolagus cuniculus

Functional Description

Protein Length

420

Protein Sequence
(FASTA)

LLDYRAVGKL GEGTFSEVVK LQNLRDGNYY ACKRMRQHFE SLEQVNSLRE VQALRRLNPH 60

PNILTLHEVV FDRNSGCLAL ICELMDMNVY ELIRGRRHPL PEKRIVRYMY QLCRALDHMH 120

RNGIFHRDVK PENILIKQDV LKLGDFGSCR SIYSKQPYTE YISTRWYRAP ECLLTDGFYT 180

YKMDVWSAGC VFYEIASLRP LFPGTNELDQ ISKIHDVIGT PAQETLTKFQ QSRAMNFDFP 240

FKKGSGIPLP TASLSPQCLS LLHAMVAYDP DTRIAAHQAL QHPYFQEQRA AERQALAGHR 300

RAAFPEHAGA PEPPSHGWPM AKEGRKQKAA LKQEDAQPRR AGPGYVTELP PLQLPAATKL 360

SSHSSPALPS AFAWGASGTV PRLRPLQRRG PDKQRDARRD AKPHLKPWRL PAIDRKGGGC 420

Nucleotide Sequence
(FASTA)

CTCCTAGACT ACAGAGCGGT TGGGAAACTA GGCGAAGGGA CGTTTTCCGA AGTCGTGAAG 60

CTGCAGAACC TGAGGGATGG AAACTACTAC GCCTGCAAGC GGATGAGGCA GCACTTCGAA 120

AGCCTTGAGC AAGTGAACAG CCTTCGAGAG GTACAAGCCC TGAGGCGCCT GAATCCACAC 180

CCCAACATCC TCACGCTGCA CGAGGTGGTG TTCGACAGGA ACTCTGGTTG TCTTGCACTG 240

ATATGTGAAC TTATGGACAT GAATGTTTAT GAACTAATAC GAGGGAGGAG ACACCCACTG 300

CCAGAGAAGA GAATCGTGCG CTACATGTAC CAGCTCTGCC GAGCCCTGGA CCACATGCAC 360

AGGAACGGCA TATTTCACAG AGACGTCAAA CCCGAAAATA TACTAATAAA GCAGGACGTC 420

CTGAAATTAG GGGACTTCGG CTCGTGCCGG AGCATCTACT CCAAGCAGCC GTACACGGAG 480

TACATCTCCA CCCGCTGGTA CCGGGCCCCG GAGTGCCTCC TGACCGACGG CTTCTACACG 540

TACAAGATGG ACGTGTGGAG TGCCGGCTGC GTGTTCTACG AGATTGCCAG CCTGCGGCCC 600

CTCTTCCCTG GGACCAATGA ACTGGACCAA ATCTCAAAAA TCCACGATGT CATCGGCACG 660

CCCGCGCAGG AGACCCTCAC CAAGTTCCAA CAGTCGAGAG CTATGAATTT TGATTTTCCT 720

TTTAAAAAGG GGTCAGGAAT ACCTCTGCCG ACAGCCAGTC TGTCCCCACA ATGCCTCTCC 780

CTCCTGCATG CCATGGTGGC CTACGACCCC GACACGCGAA TCGCTGCCCA CCAGGCCCTA 840

CAGCACCCCT ACTTCCAGGA GCAGAGGGCA GCAGAGAGAC AGGCTCTGGC TGGCCATAGA 900

AGAGCTGCCT TCCCAGAGCA CGCCGGGGCC CCAGAACCAC CCAGTCACGG CTGGCCGATG 960

GCCAAGGAGG GCAGGAAGCA GAAGGCGGCC CTGAAGCAAG AGGACGCCCA GCCCCGGAGA 1020

GCAGGCCCAG GCTACGTCAC GGAGCTGCCC CCGCTGCAGC TCCCGGCAGC GACCAAACTA 1080

TCCTCGCACT CCAGCCCCGC GCTGCCCTCG GCGTTTGCCT GGGGGGCGAG CGGGACGGTG 1140

CCCCGGCTGA GACCCCTGCA GCGCCGCGGG CCCGACAAGC AGAGGGACGC CCGCAGGGAC 1200

GCGAAGCCTC ACCTGAAGCC CTGGCGCCTG CCCGCCATCG ACAGGAAAGG TGGCGGGTGC 1260

TGA 1263

Domain Profile

S: 1     yklikklGdGtfgevllakslktgelvaikkmkrkfesleevtnlrevkslkklnahdni  60

         y+++ klG+Gtf+ev++ ++l++g+++a+k+m+++fesle+v++lrev++l++ln+h+ni

Q: 4     YRAVGKLGEGTFSEVVKLQNLRDGNYYACKRMRQHFESLEQVNSLREVQALRRLNPHPNI  63

         899*********************************************************

S: 61    iklkeviidrendslylvlelmeenlyqlikdrrkllsesklksilyqilkglafihkhg  120

         ++l+ev++dr+++ l+l++elm++n+y+li++rr+ l+e+++ +++yq++++l+++h++g

Q: 64    LTLHEVVFDRNSGCLALICELMDMNVYELIRGRRHPLPEKRIVRYMYQLCRALDHMHRNG  123

         ************************************************************

S: 121   ffhrdlkPenilikgselvkladfGlarevrsknPytdyvstrwyraPevllrsgvyssp  180

         +fhrd+kPenilik ++++kl+dfG++r+++sk+Pyt+y+strwyraPe+ll++g+y+++

Q: 124   IFHRDVKPENILIK-QDVLKLGDFGSCRSIYSKQPYTEYISTRWYRAPECLLTDGFYTYK  182

         **************.*********************************************

S: 181   ldlwavGcvlaevavlrplfPGaseidqifkilevlGtPkkkewdeayklasalnlkfpq  240

         +d+w++Gcv++e+a+lrplfPG++e+dqi+ki++v+GtP+++++++ +++++a+n++fp+

Q: 183   MDVWSAGCVFYEIASLRPLFPGTNELDQISKIHDVIGTPAQETLTK-FQQSRAMNFDFPF  241

         **********************************************.*************

S: 241   vegsslktlvsnaskealellkdllaydPderataqqalkypyf  284

         ++gs+++  ++++s ++l+ll++++aydPd r++a+qal++pyf

Q: 242   KKGSGIPLPTASLSPQCLSLLHAMVAYDPDTRIAAHQALQHPYF  285

         *******************************************9

Domain Sequence
(FASTA)

YRAVGKLGEG TFSEVVKLQN LRDGNYYACK RMRQHFESLE QVNSLREVQA LRRLNPHPNI 60

LTLHEVVFDR NSGCLALICE LMDMNVYELI RGRRHPLPEK RIVRYMYQLC RALDHMHRNG 120

IFHRDVKPEN ILIKQDVLKL GDFGSCRSIY SKQPYTEYIS TRWYRAPECL LTDGFYTYKM 180

DVWSAGCVFY EIASLRPLFP GTNELDQISK IHDVIGTPAQ ETLTKFQQSR AMNFDFPFKK 240

GSGIPLPTAS LSPQCLSLLH AMVAYDPDTR IAAHQALQHP YF 282

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Dasypus novemcinctus"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013