EKS-ORC-00194

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORC-00194

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/NKF3	551.6	7.9E-166	1318	1648	331

Status

Unreviewed

Ensembl Protein

ENSOCUP00000013356

UniProt Accession

G1T9P1;

Protein Name

Protein Synonyms/Alias

Gene Name

LOC100342340

Gene Synonyms/Alias

LOC100342340;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOCUG00000015548	ENSOCUP00000018284	ENSOCUT00000029382
ENSOCUG00000015548	ENSOCUP00000013356	ENSOCUT00000015542

Organism

Oryctolagus cuniculus

Functional Description

Protein Length

1731

Protein Sequence
(FASTA)

MSACNTFTEH VWKPGECKNC FKPKSLHQLP PDSEQAPVTH GNVKTNANQS NNHRIRNTGN 60

FRPPVAKKPT IAVKPTMMVA DGQSVCGELS IQEHCENKPV IVGWNRNRTA LSQKPLNNNQ 120

DDGEGLSHVP KPYGGTDSTK VANNNNSGLT EVLKEIAGLD AAPQTGGSEA NSRETFLGRI 180

NDCYKRSLER KLPPSCMLGG TRDAQGKHVV LSGSTEVISN EGGRFCYPEF SSGEESEEDV 240

LFSNLEEERE SWDESDEELL AMEIRMRGQP RFANFRANTL SPVRFFVDKK WNTVPLRNKS 300

LQRICAVDYD DSYDEILNGY EERSVASCGQ ESVQSMLSSD STSPDSSLTE ESRSETASSL 360

SQKICNGGLS PGNPGDPEDT KETEPSPESL LGSSQEKDPS QASKNAAKAP ETHKAVLALR 420

LEEKDGKIAV QTEKQEGKAS TDVAGQAVTI NLVPVEEQAK PYRVVNLEQP LCKPYTVVDV 480

SAAMASEHLE GPVGSSKTKG SVSTPSSPVT SPAPTPGQIS AHFQKSSAIR YQEVWTSSTS 540

PRQKIPKVEL ITGGTGPNVP PRKNCHKSAP TSPTATNISS KTIPVKSPNL SEIKFNSYNN 600

AGMPPFPIII HDEPTYARSS KNAIKVPIVI NPNAYDNLAI YKSFLGTSGE LSVKEKTTSV 660

ISHTYEEIET ESHAGAPDKA TGKPADCPQA KASSNSAERK RGSVAQKVQE FNSCLSRGQS 720

SPQRSYSSSH SSPAKIQRSA REPVAKTESQ ESPAAGGSRE KASAVLSQIV ASIQPPPSPP 780

EVPPSSPKAC SADESAPKST PVRPQSLFTT QPSGEAEAPQ TTESPTTSKG PRDPLPKPVT 840

SPPSKLVGSP QGEPPPPFPP PRSTSSPYHA GNLLQRHFTN WAKPTSPVRS TEAESVLPSE 900

GSRRAADAKP KRWISFKSFF RRRKTDEDDD KEKEREKGRL VGLDGTVIHM LPPPPVQRHH 960

WFTEAKGESS EKPALVFMYR CDPAQGQLGV DQSKAGAGQA AASEQGRAED VLSPDSEKKE 1020

RSHPSPSQAL QICFSHVTRG VTEDFSPRDP RTVAVKQGGA DGTSMAPALP LPALEKEEEK 1080

EDTSDPLDLS PCSATYSNLG QSRAAMIPPK HPRQPKGALD DAIAFGGKAD QEAPNVSHPT 1140

PPPLPKKMII RANTEPISKE LQKSMESSLC VLANPTYDID PNWDASSAGS SVSYELKGLD 1200

IESCDSLERP LHRERPVPSA ANSVSSLTAL SIKDRFSNST ESLSSRRGPS SRQGRGIQKP 1260

QRQALYRGLE NREEVVGKIR SLHTDALKKL ATQCEDLFMA GQKDQLRFGV DSWSDFRLTS 1320

DKPCCEAGDA VYYTASYAKD PLSNYAVKIC KSKAKESQQY YHSLAVRQSL AVHFNIQQDC 1380

GHFLAEVPSR LLPWEDPDAP GKEDDEVEEN GAGAEGGTGG TPPEPCSETE ASRKEGQGGA 1440

GRRQRSHVVV ITREVPHLTV ADFVRDSLAH HGKSPDVYER QVCLLLLQLC SGLEHLKPYH 1500

VTHCDLRLEN LLLVHYQPGG PGPAEPGPAS SCPTRLLVSN FSQAKQKSHL VDPDILRDQS 1560

RLAPEIITAT QYKKCDEFQT GILIYEMLHL PNPFDEHPEL KEKEYTRADL PRIPLRSHYS 1620

RGLQQLASCL LNPNPSERIL ISDAKGILQC LLWGPREDLF QTLSASPSLA QRSALLQNWL 1680

DIKRTLLMIK FAEKSLDREA GVSLEDWLCA QYLAFATTDS LGCIVKILQH R 1731

Nucleotide Sequence
(FASTA)

ATGTCTGCTT GTAACACCTT TACTGAACAC GTTTGGAAAC CTGGTGAATG CAAGAATTGC 60

TTTAAACCTA AAAGCTTGCA CCAGCTCCCC CCGGACTCTG AGCAGGCGCC CGTCACCCAC 120

GGCAACGTGA AAACGAATGC CAACCAGAGC AACAACCACC GCATCAGGAA CACGGGGAAT 180

TTCCGGCCTC CTGTGGCTAA AAAACCCACG ATAGCTGTGA AGCCCACGAT GATGGTGGCA 240

GATGGGCAAA GTGTGTGTGG GGAGCTTAGC ATCCAGGAAC ACTGCGAGAA CAAGCCTGTC 300

ATCGTGGGAT GGAACCGAAA CAGGACCGCC TTGAGTCAGA AGCCGCTGAA CAACAACCAG 360

GACGACGGCG AAGGGCTTAG CCACGTTCCC AAGCCTTACG GCGGCACCGA CAGCACGAAG 420

GTCGCCAACA ACAACAACAG CGGGCTGACC GAAGTGCTCA AGGAGATCGC GGGCCTGGAC 480

GCCGCCCCTC AGACCGGGGG CAGCGAGGCC AACTCCAGGG AGACCTTCTT GGGGAGGATA 540

AATGACTGCT ACAAACGGTC CCTGGAGAGA AAGCTCCCCC CGAGCTGCAT GCTGGGCGGC 600

ACGAGGGACG CTCAGGGCAA GCACGTGGTT CTGAGCGGGA GCACAGAAGT GATCAGCAAC 660

GAAGGGGGCC GGTTCTGTTA CCCCGAGTTC TCCAGCGGCG AGGAGAGCGA GGAGGACGTG 720

CTTTTCAGCA ACCTGGAGGA GGAGCGCGAG AGCTGGGATG AGAGCGACGA GGAGCTGCTG 780

GCCATGGAGA TCCGCATGCG AGGGCAGCCT CGCTTCGCCA ACTTCAGGGC CAACACTCTG 840

TCTCCGGTTC GCTTCTTCGT GGACAAAAAG TGGAATACGG TCCCCCTGCG AAACAAGTCC 900

CTGCAGAGGA TCTGTGCTGT CGACTACGAC GACAGCTACG ACGAGATCCT GAATGGCTAT 960

GAGGAGCGCT CCGTGGCCTC CTGCGGGCAG GAAAGTGTCC AGAGCATGCT GTCCTCTGAC 1020

TCCACCTCCC CAGACTCCTC TCTCACGGAG GAATCCCGTT CCGAGACAGC CAGCAGTTTG 1080

TCTCAGAAGA TTTGCAATGG GGGGTTATCT CCTGGCAACC CAGGAGACCC CGAGGACACG 1140

AAGGAAACGG AGCCCAGTCC CGAGAGCCTC CTGGGTAGCA GTCAGGAGAA GGACCCATCA 1200

CAAGCTTCCA AAAACGCAGC CAAAGCGCCA GAGACGCACA AAGCAGTCCT CGCCCTCCGA 1260

TTAGAAGAGA AGGACGGCAA AATCGCCGTG CAGACGGAGA AGCAGGAGGG CAAAGCCTCC 1320

ACGGATGTCG CTGGGCAAGC CGTGACCATC AACCTCGTCC CTGTAGAAGA GCAAGCGAAG 1380

CCCTACCGAG TGGTGAACCT GGAGCAGCCA CTGTGCAAGC CGTATACGGT GGTGGACGTG 1440

TCAGCAGCCA TGGCCAGCGA ACACCTCGAG GGCCCTGTCG GCAGCTCCAA GACAAAAGGC 1500

TCCGTCTCCA CTCCAAGCTC TCCTGTGACA TCACCTGCGC CGACTCCAGG ACAAATAAGT 1560

GCCCATTTCC AGAAGTCCAG TGCAATACGA TACCAGGAAG TGTGGACTTC CAGCACCAGT 1620

CCAAGACAGA AGATACCGAA AGTGGAGTTA ATTACCGGTG GAACTGGACC CAACGTGCCT 1680

CCCAGGAAAA ACTGTCACAA GTCCGCACCT ACGTCGCCCA CAGCTACAAA CATTTCCTCC 1740

AAAACCATCC CTGTCAAGTC ACCGAACTTG TCCGAAATAA AGTTCAATAG TTACAACAAT 1800

GCCGGGATGC CGCCTTTCCC CATCATCATT CACGACGAGC CCACGTACGC TCGGAGTTCC 1860

AAAAATGCCA TCAAAGTGCC CATTGTCATC AATCCGAATG CATACGACAA TCTGGCCATC 1920

TACAAAAGTT TTCTGGGGAC AAGTGGGGAG CTCTCGGTGA AGGAGAAAAC CACGAGCGTC 1980

ATCAGCCACA CTTACGAGGA AATAGAAACC GAGAGCCACG CCGGGGCCCC GGATAAGGCC 2040

ACTGGCAAAC CCGCCGACTG CCCCCAGGCC AAGGCGTCTT CCAACAGCGC AGAGCGGAAA 2100

AGGGGCTCCG TGGCCCAGAA GGTGCAGGAG TTTAACAGCT GTCTCAGCAG GGGCCAGTCT 2160

TCACCGCAGA GGAGCTACAG TTCCAGCCAC AGCTCCCCAG CGAAGATCCA GAGAAGCGCT 2220

CGGGAGCCCG TGGCCAAAAC GGAGTCCCAG GAGTCCCCGG CGGCGGGTGG CAGCCGGGAG 2280

AAAGCCAGCG CGGTGCTCTC TCAGATCGTG GCTTCCATCC AGCCCCCACC GTCCCCCCCG 2340

GAGGTCCCGC CGTCCAGCCC GAAGGCGTGC AGTGCCGACG AGAGCGCCCC GAAGAGCACA 2400

CCCGTCCGGC CCCAATCCCT CTTCACCACG CAGCCCAGTG GGGAGGCCGA AGCACCTCAG 2460

ACCACCGAAA GTCCCACCAC CAGCAAAGGA CCGAGAGATC CCCTCCCAAA GCCTGTCACC 2520

TCTCCTCCCT CCAAATTAGT GGGCAGCCCC CAGGGCGAGC CCCCACCCCC CTTCCCCCCG 2580

CCCCGCTCCA CTTCCTCCCC TTACCACGCA GGGAACCTTC TGCAGAGGCA TTTCACCAAC 2640

TGGGCCAAGC CCACCAGCCC CGTGCGGTCG ACAGAGGCCG AGTCCGTGCT GCCCTCCGAA 2700

GGCAGCCGGC GGGCAGCTGA CGCGAAGCCC AAGCGCTGGA TATCCTTCAA AAGCTTCTTC 2760

CGCCGCCGGA AAACGGACGA GGACGACGAC AAAGAGAAAG AGCGGGAGAA GGGGAGGCTG 2820

GTGGGCCTGG ACGGCACGGT CATCCACATG CTGCCGCCCC CTCCAGTGCA GCGCCATCAC 2880

TGGTTCACAG AGGCGAAGGG AGAGTCGAGC GAGAAGCCAG CGCTCGTCTT CATGTACAGG 2940

TGTGACCCTG CGCAAGGCCA GCTCGGCGTG GACCAGAGCA AGGCTGGGGC AGGCCAGGCC 3000

GCGGCTTCAG AGCAGGGCAG AGCGGAGGAC GTGCTGTCGC CGGACTCGGA GAAGAAGGAA 3060

AGGAGTCACC CTTCCCCGTC ACAGGCCCTT CAGATTTGTT TTAGTCACGT GACCCGTGGA 3120

GTGACAGAGG ACTTTTCTCC TCGGGATCCA AGAACAGTTG CTGTGAAGCA AGGTGGCGCG 3180

GATGGCACGT CCATGGCCCC AGCATTGCCC CTGCCTGCCC TGGAAAAGGA AGAGGAGAAG 3240

GAGGACACTT CAGATCCCCT GGACCTGAGC CCCTGTAGTG CAACATACAG CAATTTGGGG 3300

CAGTCCAGAG CAGCCATGAT ACCTCCCAAG CACCCCCGGC AGCCCAAGGG CGCTCTGGAC 3360

GATGCCATCG CCTTTGGGGG AAAAGCAGAC CAAGAAGCCC CTAATGTTTC CCACCCTACA 3420

CCACCCCCAC TGCCAAAGAA GATGATCATC AGAGCCAACA CAGAGCCAAT CTCCAAGGAA 3480

CTCCAGAAAT CCATGGAGAG CAGCCTTTGT GTCCTGGCTA ACCCCACCTA TGATATCGAC 3540

CCCAACTGGG ATGCCAGCAG TGCTGGCTCC TCCGTCAGCT ATGAACTCAA GGGGCTGGAC 3600

ATCGAGTCTT GTGACTCCTT GGAGAGACCT CTGCACAGGG AGAGACCCGT CCCCTCGGCC 3660

GCAAACAGCG TCTCCAGCTT GACCGCTCTC AGTATTAAGG ACCGGTTTTC CAACAGCACG 3720

GAGTCCCTGT CCAGCCGACG GGGTCCCTCC TCTAGACAGG GCCGAGGCAT CCAGAAGCCA 3780

CAGAGACAAG CACTTTATCG AGGACTGGAG AATCGGGAGG AAGTGGTGGG CAAAATCCGC 3840

AGCCTTCACA CGGACGCCTT GAAGAAGCTG GCCACTCAGT GTGAAGACCT CTTCATGGCT 3900

GGCCAGAAAG ACCAGCTCCG TTTTGGGGTG GACAGCTGGT CAGACTTCCG GCTAACCAGC 3960

GACAAGCCGT GCTGCGAGGC AGGCGATGCT GTTTACTACA CCGCCTCCTA TGCGAAGGAT 4020

CCGCTGAGTA ACTACGCGGT CAAGATCTGT AAGAGCAAGG CTAAAGAGTC CCAGCAGTAT 4080

TATCACAGCC TGGCCGTCCG GCAGAGCCTG GCCGTCCATT TTAACATCCA GCAGGACTGC 4140

GGCCACTTCC TGGCCGAGGT CCCCAGCCGG CTGCTTCCCT GGGAGGACCC CGATGCCCCT 4200

GGAAAGGAAG ACGACGAAGT GGAAGAGAAT GGAGCAGGGG CGGAAGGGGG GACCGGCGGC 4260

ACACCCCCAG AGCCGTGCTC CGAAACAGAG GCGTCCCGGA AGGAGGGCCA GGGCGGTGCG 4320

GGCCGGCGGC AGAGAAGCCA CGTCGTGGTC ATCACCCGGG AGGTCCCCCA CCTCACCGTG 4380

GCCGACTTCG TGCGGGACTC TCTGGCCCAC CACGGGAAAA GCCCGGATGT GTACGAGAGG 4440

CAGGTGTGCC TGCTGCTCTT ACAGCTCTGC TCTGGCCTCG AGCACCTCAA GCCCTACCAC 4500

GTCACTCACT GCGACCTTCG GCTGGAGAAC CTGCTGCTTG TCCACTACCA GCCGGGGGGC 4560

CCGGGGCCCG CGGAGCCCGG CCCCGCCTCG TCTTGTCCCA CGCGCCTCCT CGTGAGCAAC 4620

TTCTCGCAGG CCAAGCAGAA GAGCCACCTG GTGGACCCCG ACATCCTCCG GGACCAGTCG 4680

CGCCTGGCCC CGGAGATCAT CACGGCCACC CAGTACAAGA AGTGCGACGA GTTCCAGACC 4740

GGCATCCTCA TCTATGAGAT GCTGCACCTG CCCAACCCCT TCGACGAGCA CCCCGAGCTG 4800

AAGGAGAAGG AGTACACGCG GGCGGACCTG CCACGCATCC CGCTGCGCTC CCACTACTCG 4860

CGGGGCCTGC AGCAGCTGGC CAGCTGCCTC CTGAACCCCA ACCCTTCCGA GCGGATCCTC 4920

ATCTCCGACG CCAAAGGCAT CCTGCAGTGT CTGCTCTGGG GCCCCCGGGA GGATCTCTTC 4980

CAGACGCTCA GCGCCTCCCC GAGCCTGGCG CAGAGGAGCG CGCTGCTCCA GAACTGGCTG 5040

GACATCAAGC GGACGCTGCT GATGATCAAG TTCGCAGAGA AGTCGCTGGA CAGGGAGGCC 5100

GGCGTGAGCC TCGAGGACTG GCTGTGCGCG CAGTACTTGG CCTTCGCCAC CACAGACTCC 5160

CTCGGCTGCA TCGTGAAGAT CCTGCAACAC CGT 5193

Domain Profile

S: 1     ltsdkpcceagdavyytasyakdplsnyavkickskekksqsy.....vrqslpvhfniq  55

         ltsdkpcceagdavyytasyakdplsnyavkicksk+k+sq+y     vrqsl+vhfniq

Q: 1318  LTSDKPCCEAGDAVYYTASYAKDPLSNYAVKICKSKAKESQQYyhslaVRQSLAVHFNIQ  1377

         79**********************************************************

S: 56    qdcGhflaevpsrlla..dpdapekd...................pkpasetepsake..  92

         qdcGhflaevpsrll+  dpdap k+                   p+p+sete+s+ke

Q: 1378  QDCGHFLAEVPSRLLPweDPDAPGKEddeveengagaeggtggtpPEPCSETEASRKEgq  1437

         ***********************99889********************************

S: 93    .......rdhvvvitrevphltvadfvrdslashraepelyerrvcllllqlcsGlehlk  145

                r+hvvvitrevphltvadfvrdsla+h+++p++yer+vcllllqlcsGlehlk

Q: 1438  ggagrrqRSHVVVITREVPHLTVADFVRDSLAHHGKSPDVYERQVCLLLLQLCSGLEHLK  1497

         ************************************************************

S: 146   eygvihrdlrlenlllvhlqpqagaaqaaapaepaptsaapsaapaattasqegprekql  205

         +y+v+h+dlrlenlllvh+qp      +++paep p+s++p

Q: 1498  PYHVTHCDLRLENLLLVHYQP-----GGPGPAEPGPASSCP-------------------  1533

         *********************.....46789**********...................

S: 206   trlivsnflkakqksgglvdlqikkdqarlapeivsasqykkfdefqtGiliyellhlpn  265

         trl+vsnf++akqks +lvd++i++dq+rlapei++a+qykk+defqtGiliye+lhlpn

Q: 1534  TRLLVSNFSQAKQKS-HLVDPDILRDQSRLAPEIITATQYKKCDEFQTGILIYEMLHLPN  1592

         9**************.********************************************

S: 266   pfevraelkereyrredlprlpllslysrGlqqlasllleadpikriliseakrvl  321

         pf++++elke+ey+r+dlpr+pl+s ysrGlqqlas+ll+++p++rilis+ak++l

Q: 1593  PFDEHPELKEKEYTRADLPRIPLRSHYSRGLQQLASCLLNPNPSERILISDAKGIL  1648

         ******************************************************98

Domain Sequence
(FASTA)

LTSDKPCCEA GDAVYYTASY AKDPLSNYAV KICKSKAKES QQYYHSLAVR QSLAVHFNIQ 60

QDCGHFLAEV PSRLLPWEDP DAPGKEDDEV EENGAGAEGG TGGTPPEPCS ETEASRKEGQ 120

GGAGRRQRSH VVVITREVPH LTVADFVRDS LAHHGKSPDV YERQVCLLLL QLCSGLEHLK 180

PYHVTHCDLR LENLLLVHYQ PGGPGPAEPG PASSCPTRLL VSNFSQAKQK SHLVDPDILR 240

DQSRLAPEII TATQYKKCDE FQTGILIYEM LHLPNPFDEH PELKEKEYTR ADLPRIPLRS 300

HYSRGLQQLA SCLLNPNPSE RILISDAKGI L 331

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0015629	; C:actin cytoskeleton
GO:0005925	; C:focal adhesion
GO:0005524	; F:ATP binding
GO:0004715	; F:non-membrane spanning protein tyrosine kinase activity
GO:0016477	; P:cell migration
GO:0046777	; P:protein autophosphorylation
GO:0034446	; P:substrate adhesion-dependent cell spreading

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR008266	; Tyr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00109	; PROTEIN_KINASE_TYR; 1.

Prints

Created Date

20-Feb-2013