EKS-ORC-00190

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORC-00190

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	484.9	6.8E-146	4	286	283

Status

Unreviewed

Ensembl Protein

ENSOCUP00000013542

UniProt Accession

G1TA58;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL3

Gene Synonyms/Alias

CDKL3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOCUG00000015764	ENSOCUP00000013542	ENSOCUT00000015763

Organism

Oryctolagus cuniculus

Functional Description

Protein Length

592

Protein Sequence
(FASTA)

MEMYETLGKV GEGSYGTVMK CKHKNTGQIV AIKIFYEKPE KSVNKIALRE IKFLKQFRHE 60

NLVNLIEVFR QKKKIHLVFE FIDHTVLDEL QHYCHGLESK RLRKYLFQIL RAVDYLHSNN 120

IIHRDIKPEN ILVSQSGITK LCDFGFARTL AAPGDVYTDY VATRWYRAPE LVLKDTSYGK 180

PVDIWALGCM IIEMATGNPF LPSSSDLDLL HKIVSKVGNL TPHLQNIFSK NPIFTGVVLP 240

QVQHTRNARK KYPKLNGLLA DIVHACLQID PAERISSPEL LHHEYFTRDG FIEKFIPELR 300

AKLLQEARVN SFIRPKTYCK ENEFKEDERK IVYNNTLLSS SFWGKVRILI FISSCLTILY 360

IKVKGGKGAI SELKKTEYEV EHCRQDGTED AHAVSEHTRP VSSRPASPVN SSTNSSSMKE 420

DAQSGGCMTM PPINPTCGNL MTANLNSNLS HPNPRLAERA KRRRTSLQYV GQAVSDSRQD 480

DGGAVQVSQV EKSVCKGQSG QVANGNKRKL NFSRSDRKEF HFPELPFTIR SKEMKGMEEV 540

KQVKMLKKDS KRTDSSKIQT LLHMDHKQEK QEGGDGHCEG KNLKRNRFFF CR 592

Nucleotide Sequence
(FASTA)

ATGGAGATGT ATGAAACCCT TGGCAAAGTG GGAGAGGGAA GTTACGGAAC GGTCATGAAA 60

TGTAAACATA AGAACACTGG GCAGATAGTG GCCATTAAGA TATTCTATGA GAAACCAGAA 120

AAGTCTGTCA ACAAAATTGC ATTGAGAGAG ATAAAGTTTC TAAAGCAATT TCGTCATGAA 180

AACCTGGTCA ATCTGATCGA AGTTTTCAGA CAGAAAAAGA AAATCCACCT GGTGTTTGAG 240

TTTATCGACC ACACAGTGCT GGATGAGCTG CAGCACTACT GCCACGGGCT GGAGAGCAAG 300

CGGCTCAGGA AGTACCTGTT CCAGATCCTT CGAGCAGTCG ACTATCTGCA CAGTAACAAC 360

ATCATTCATC GAGATATAAA ACCTGAGAAT ATTTTAGTGT CCCAGTCGGG AATTACTAAG 420

CTCTGTGATT TTGGTTTTGC ACGAACTCTA GCAGCTCCCG GGGACGTTTA TACAGACTAT 480

GTGGCCACGC GCTGGTACAG AGCTCCAGAA TTAGTACTGA AAGATACTTC CTACGGAAAA 540

CCTGTGGATA TCTGGGCTTT GGGCTGTATG ATTATTGAGA TGGCCACTGG AAATCCCTTT 600

CTTCCCAGCA GCTCTGATTT GGATTTACTC CATAAAATTG TTTCAAAAGT AGGCAATTTA 660

ACACCTCACT TGCAGAATAT CTTTTCCAAG AATCCCATTT TTACTGGCGT GGTCCTCCCT 720

CAAGTTCAAC ACACCAGAAA TGCAAGAAAA AAATACCCAA AGCTTAATGG ATTGCTGGCA 780

GATATAGTTC ATGCTTGTTT ACAGATTGAT CCTGCTGAGC GGATATCATC TCCTGAACTT 840

CTGCATCATG AGTATTTTAC TAGAGATGGA TTTATTGAAA AATTCATACC AGAACTGAGA 900

GCTAAGTTAC TACAAGAAGC AAGAGTCAAC TCATTTATAA GGCCAAAAAC ATATTGTAAA 960

GAAAATGAAT TTAAGGAAGA TGAAAGAAAA ATAGTATATA ACAATACATT GCTAAGTAGT 1020

TCTTTTTGGG GAAAGGTAAG GATTTTGATT TTTATTTCAT CCTGTTTAAC TATATTATAT 1080

ATTAAAGTTA AAGGCGGAAA AGGAGCTATC TCAGAACTGA AAAAGACAGA GTATGAAGTG 1140

GAACATTGTC GACAGGATGG AACGGAAGAT GCTCATGCTG TGTCCGAGCA CACCAGACCT 1200

GTAAGCAGCA GACCAGCCAG CCCCGTCAAT TCCAGCACTA ATTCCAGCAG CATGAAAGAA 1260

GATGCGCAGT CTGGAGGCTG TATGACAATG CCACCCATCA ATCCGACCTG CGGTAATTTG 1320

ATGACTGCAA ATCTCAACTC TAATCTCTCC CACCCCAATC CAAGGTTAGC TGAAAGAGCA 1380

AAAAGGAGAC GCACTTCTTT ACAGTATGTT GGACAAGCTG TGTCTGACAG CAGGCAGGAT 1440

GATGGAGGTG CCGTGCAAGT AAGCCAAGTG GAGAAGAGTG TATGTAAGGG TCAAAGTGGC 1500

CAGGTGGCAA ATGGAAACAA AAGGAAGCTG AATTTTTCCA GATCTGACAG AAAAGAATTC 1560

CATTTCCCAG AACTGCCTTT CACAATACGC TCTAAGGAAA TGAAAGGAAT GGAAGAAGTT 1620

AAGCAGGTAA AAATGCTGAA GAAAGATTCA AAGAGAACAG ATTCATCTAA AATACAAACT 1680

TTACTTCACA TGGACCATAA GCAAGAAAAG CAAGAGGGTG GAGATGGCCA TTGTGAGGGG 1740

AAGAATTTGA AGAGGAACAG ATTTTTTTTC TGTAGA 1776

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         ye+lgkvGeGsyG+v+kc++k+tgqivaik f+e+++ k+v+kialreik+lkq++henl

Q: 4     YETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYEKPE-KSVNKIALREIKFLKQFRHENL  62

         9***********************************9.9*********************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnl+evfr+kkk++lvfe++d+tvldel++y++G+e+++++k+l+qil+a++++h+nnii

Q: 63    VNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAVDYLHSNNII  122

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrdikpenil+s+sg++klcdfGfar+laapgdvytdyvatrwyrapel+++dt+yGk+v

Q: 123   HRDIKPENILVSQSGITKLCDFGFARTLAAPGDVYTDYVATRWYRAPELVLKDTSYGKPV  182

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         d+wa+Gc+++e++tG+p++p++sd+d l+ki+ ++G+l+p+ q+ifskn++f+Gv+lp+v

Q: 183   DIWALGCMIIEMATGNPFLPSSSDLDLLHKIVSKVGNLTPHLQNIFSKNPIFTGVVLPQV  242

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         +++++++kkypkln +l+d++++cl++dpaer+s+ ell+heyf

Q: 243   QHTRNARKKYPKLNGLLADIVHACLQIDPAERISSPELLHHEYF  286

         *******************************************9

Domain Sequence
(FASTA)

YETLGKVGEG SYGTVMKCKH KNTGQIVAIK IFYEKPEKSV NKIALREIKF LKQFRHENLV 60

NLIEVFRQKK KIHLVFEFID HTVLDELQHY CHGLESKRLR KYLFQILRAV DYLHSNNIIH 120

RDIKPENILV SQSGITKLCD FGFARTLAAP GDVYTDYVAT RWYRAPELVL KDTSYGKPVD 180

IWALGCMIIE MATGNPFLPS SSDLDLLHKI VSKVGNLTPH LQNIFSKNPI FTGVVLPQVQ 240

HTRNARKKYP KLNGLLADIV HACLQIDPAE RISSPELLHH EYF 283

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Vicugna pacos"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013