EPS-ORC-00018

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-ORC-00018

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/aDSP	56.6	2.8E-15	75	146	72

Status

Unreviewed

Ensembl Protein

ENSOCUP00000013593

UniProt Accession

G1TAA5;

Protein Name

Protein Synonyms/Alias

Gene Name

DUSP23

Gene Synonyms/Alias

DUSP23;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOCUG00000015831	ENSOCUP00000013593	ENSOCUT00000015827

Organism

Oryctolagus cuniculus

Functional Description

Protein Length

150

Protein Sequence
(FASTA)

MGVQPPNFSW VLPGRLAGLA LPRLPAHYQF LLELGVRHLV SLTERGPPHS DSCPGLTVHR 60

LRIPDFCPPA PNQIDRFVQI VDEANARGEA VGVHCALGYG RTGTMLACYL VKEKGLAAGD 120

AIAEIRRLRP GSIETYEQEK AVFQFYQRTK 150

Nucleotide Sequence
(FASTA)

ATGGGAGTGC AGCCCCCCAA CTTCTCCTGG GTGCTGCCGG GCCGGCTGGC GGGGCTGGCG 60

CTGCCGCGGC TCCCCGCCCA CTACCAGTTC CTGCTTGAGC TGGGAGTGCG GCACCTGGTG 120

TCCCTGACGG AGCGCGGGCC CCCGCACAGC GACAGCTGCC CGGGCCTCAC CGTGCACCGG 180

CTGCGCATCC CGGACTTCTG CCCGCCCGCC CCCAACCAGA TCGACCGCTT CGTGCAGATC 240

GTGGACGAGG CCAACGCGCG GGGCGAGGCG GTGGGAGTGC ACTGCGCCCT GGGCTATGGC 300

CGCACTGGCA CCATGCTGGC CTGCTACCTG GTGAAGGAGA AGGGCTTGGC TGCAGGCGAT 360

GCCATTGCTG AAATCCGACG CCTGCGACCT GGCTCCATCG AGACCTATGA ACAAGAGAAG 420

GCCGTCTTCC AGTTCTACCA GCGAACTAAG TAA 453

Domain Profile

S: 73    deaaefideakekggkvlvHCaaGvsRSatlvlaYLmkveglslsdAieavkrkrpsiep  132

         d++++++dea+ +g++v vHCa G++R++t++ +YL+k +gl++ dAi +++r rp  ++

Q: 75    DRFVQIVDEANARGEAVGVHCALGYGRTGTMLACYLVKEKGLAAGDAIAEIRRLRPGSIE  134

         7899******************************************************99

S: 133   negfleQLlele  144

         + ++ +   ++

Q: 135   TYEQEKAVFQFY  146

999988877775

Domain Sequence
(FASTA)

DRFVQIVDEA NARGEAVGVH CALGYGRTGT MLACYLVKEK GLAAGDAIAE IRRLRPGSIE 60

TYEQEKAVFQ FY 72

Keyword

Complete proteome; Hydrolase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0004725	; F:protein tyrosine phosphatase activity
GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0035335	; P:peptidyl-tyrosine dephosphorylation

KEGG

InterPros

IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR026067	; Dual_phosphatase_23.
IPR000387	; Tyr/Dual-specificity_Pase.
IPR016130	; Tyr_Pase_AS.

Pfam

PF00782

; DSPc; 1.

SMARTs

Prosites

PS00383	; TYR_PHOSPHATASE_1; 1.
PS50056	; TYR_PHOSPHATASE_2; 1.

Prints

Created Date

20-Feb-2013