EKS-ORC-00307

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORC-00307

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	317.9	5.9E-95	71	344	274

Status

Unreviewed

Ensembl Protein

ENSOCUP00000015356

UniProt Accession

G1TEM4;

Protein Name

Protein Synonyms/Alias

Gene Name

STK39

Gene Synonyms/Alias

STK39;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOCUG00000017874	ENSOCUP00000015356	ENSOCUT00000017875

Organism

Oryctolagus cuniculus

Functional Description

Protein Length

551

Protein Sequence
(FASTA)

MAEPSGSPVH VQLPPQAAPV TVAAAAPAVT TAAPAAAPAV PAASAPAPVP APAPSPAAQA 60

VGWPICRDAN ELQEVIGSGA TAVVQAALCK PRQERVAIKR INLEKCQTSM DELLKEIQAM 120

SQCSHPNVVT YYTSFVVKDE LWLVMKLLSG GSMLDIIKYI VNRGEHKNGV LEEAIIATIL 180

KEVLEGLDYL HRNGQIHRDL KAGNILLGED GSVQIADFGV SAFLATGGDV TRNKVRKTFV 240

GTPCWMAPEV MEQVRGYDFK ADMWSFGITA IELATGAAPY HKYPPMKVLM LTLQNDPPTL 300

ETGVEDKEMM KKYGKSFRKL LSLCLQKDPS KRPTAAELLK CKFFQKAKNR EYLIEKLLTR 360

TPDIAQRAKK VRRVPGSSGH LHKTEDGDWE WSDDEMDEKS EEGKAAVSQE KSRRVKEENP 420

EVAVNAGGIP EQIQSLSVRD SQGQPNASED YREASCAVNL VLRLRNSRKE LNDIRFEFTP 480

GRDTADGVSQ ELFSAGLVDG HDVVIVAANL QKIVDDPKAL KTLTFKLASG CDGSEIPDEV 540

KLIGFAQLSV S 551

Nucleotide Sequence
(FASTA)

ATGGCGGAGC CGAGCGGCTC GCCCGTGCAC GTCCAGCTTC CCCCGCAGGC GGCCCCGGTG 60

ACAGTGGCGG CGGCGGCCCC GGCGGTCACC ACAGCAGCGC CGGCCGCGGC CCCGGCGGTG 120

CCGGCCGCCT CGGCTCCGGC TCCGGTCCCG GCCCCGGCCC CAAGCCCGGC GGCGCAAGCC 180

GTCGGCTGGC CCATCTGCAG GGACGCGAAT GAGCTGCAGG AGGTTATCGG CAGTGGCGCT 240

ACTGCTGTGG TTCAGGCTGC CCTGTGCAAA CCCAGGCAAG AACGTGTAGC AATAAAGCGG 300

ATCAACTTGG AAAAATGCCA GACCAGTATG GATGAACTAT TAAAAGAAAT CCAAGCCATG 360

AGTCAGTGCA GCCATCCCAA CGTAGTGACC TATTACACCT CTTTTGTGGT GAAGGATGAA 420

CTTTGGCTGG TCATGAAATT GCTAAGTGGA GGTTCCATGT TGGATATCAT AAAATACATT 480

GTCAACCGAG GAGAGCACAA GAACGGTGTT CTGGAAGAGG CCATCATAGC AACAATTCTT 540

AAAGAGGTCT TGGAAGGCTT AGACTATCTA CACAGAAACG GTCAGATTCA CAGAGACTTG 600

AAAGCTGGCA ACATTCTTCT GGGTGAAGAT GGCTCCGTAC AAATAGCAGA TTTTGGGGTA 660

AGTGCATTCT TAGCAACTGG GGGTGATGTT ACCCGGAATA AAGTCAGAAA AACATTTGTT 720

GGAACCCCAT GTTGGATGGC CCCTGAAGTC ATGGAACAGG TGAGAGGCTA TGACTTCAAG 780

GCTGACATGT GGAGTTTTGG AATAACTGCC ATTGAACTAG CAACAGGAGC GGCGCCGTAT 840

CACAAATATC CTCCTATGAA AGTGTTAATG TTGACTCTGC AAAATGATCC GCCCACTTTA 900

GAAACCGGAG TAGAGGATAA AGAAATGATG AAAAAGTACG GCAAGTCTTT TAGAAAATTA 960

CTTTCACTGT GTCTTCAGAA AGATCCTTCC AAAAGGCCCA CAGCAGCAGA ACTTTTAAAA 1020

TGCAAATTCT TCCAGAAAGC CAAGAACAGA GAGTACCTGA TTGAGAAGCT GCTCACAAGA 1080

ACACCAGACA TAGCCCAAAG AGCCAAAAAG GTGAGAAGAG TTCCCGGGTC GAGTGGCCAT 1140

CTTCACAAAA CTGAGGACGG TGACTGGGAG TGGAGTGACG ACGAGATGGA TGAAAAAAGC 1200

GAAGAAGGGA AAGCCGCTGT TTCTCAGGAA AAGTCACGAA GAGTAAAAGA AGAAAATCCA 1260

GAGGTGGCGG TGAATGCAGG CGGCATCCCC GAGCAGATCC AGTCCCTCTC CGTGCGCGAC 1320

TCTCAGGGCC AACCCAACGC TAGTGAAGAC TACAGAGAAG CTTCTTGTGC CGTGAACCTC 1380

GTCTTAAGAT TAAGAAACTC CAGAAAGGAA CTTAATGACA TACGATTTGA GTTTACTCCA 1440

GGAAGAGATA CGGCAGATGG TGTGTCTCAG GAGCTCTTCT CTGCTGGCTT GGTGGATGGT 1500

CACGATGTAG TTATAGTGGC TGCTAACTTA CAGAAGATTG TAGATGATCC CAAAGCTTTA 1560

AAAACATTGA CATTTAAGTT GGCTTCCGGC TGTGACGGGT CGGAGATTCC TGATGAAGTG 1620

AAGCTGATCG GCTTTGCTCA GTTGAGCGTG AGCTGA 1656

Domain Profile

S: 2     elleeigkGalgkvylarekktgelvaikkinlekq.ekleelqkeisvlkklkhpnive  60

         el+e+ig+Ga++ v++a +k+++e vaik+inlek+ ++++el kei+++++++hpn+v+

Q: 71    ELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCqTSMDELLKEIQAMSQCSHPNVVT  130

         6899********************************8899********************

S: 61    ylesflkeeelwlvmeylagGslsdlvk......eelkselkEeqiayilrevlkaLeyl  114

         y++sf++++elwlvm++l+gGs+ d++k      e+++  l+E  ia+il+evl++L+yl

Q: 131   YYTSFVVKDELWLVMKLLSGGSMLDIIKyivnrgEHKNGVLEEAIIATILKEVLEGLDYL  190

         *********************************999************************

S: 115   HskkviHrdikakniLlteegeVkLsdfgvaaqlek....trkk.rktvvgtpywmAPEv  169

         H++++iHrd+ka+niLl e+g+V+++dfgv+a l++    tr+k rkt+vgtp+wmAPEv

Q: 191   HRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATggdvTRNKvRKTFVGTPCWMAPEV  250

         **********************************99888888899***************

S: 170   iaqeekgYdekaDiwslGItaielaegepPfkdleplkallkilkneppklksk......  223

         ++q  +gYd kaD+ws+GItaiela+g++P+++++p+k+l+++l+n+pp+l++

Q: 251   MEQ-VRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGvedkem  309

         **5.9**********************************************666667777

S: 224   .kkfskefkefvekclqknpekRpsasellkhkFl  257

          kk++k+f+++++ clqk+p+kRp+a+ellk kF+

Q: 310   mKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFF  344

         799******************************97

Domain Sequence
(FASTA)

ELQEVIGSGA TAVVQAALCK PRQERVAIKR INLEKCQTSM DELLKEIQAM SQCSHPNVVT 60

YYTSFVVKDE LWLVMKLLSG GSMLDIIKYI VNRGEHKNGV LEEAIIATIL KEVLEGLDYL 120

HRNGQIHRDL KAGNILLGED GSVQIADFGV SAFLATGGDV TRNKVRKTFV GTPCWMAPEV 180

MEQVRGYDFK ADMWSFGITA IELATGAAPY HKYPPMKVLM LTLQNDPPTL ETGVEDKEMM 240

KKYGKSFRKL LSLCLQKDPS KRPTAAELLK CKFF 274

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016324	; C:apical plasma membrane
GO:0016323	; C:basolateral plasma membrane
GO:0005524	; F:ATP binding
GO:0004672	; F:protein kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR024678	; Kinase_OSR1/WNK_CCT.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF12202	; OSR1_C; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013