EKS-ORC-00444

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORC-00444

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/MAPK	364.3	4.7E-109	16	305	290

Status

Unreviewed

Ensembl Protein

ENSOCUP00000015362

UniProt Accession

G1TEM9;

Protein Name

Protein Synonyms/Alias

Gene Name

MAPK15

Gene Synonyms/Alias

MAPK15;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOCUG00000017881	ENSOCUP00000015362	ENSOCUT00000017881

Organism

Oryctolagus cuniculus

Functional Description

Protein Length

554

Protein Sequence
(FASTA)

MCAAEVDAHI ARRFRLQRRL GKGAYGIVWK AVDRSTGEVV AIKKIFDAFR DQTDAQRTFR 60

EIVLLQEFGG HPNIIRLLDV IRAENDRDIY LVFESMDTDL HAVIEKGTLL KDIHKRYIFY 120

QLLRATQFLH SGHVVHRDQK PSNVLLDANC LVKLCDFGLA RSLSSVPEGP EGQPLTEYVA 180

TRWYRAPEVL LSSHWYTPGV DMWSLGCILG EMLRGRPLFP GTSTLHQLQL ILEAVPPPSE 240

EDLLALGSNY SSLVLHHLGS RPRQLLDALL PPDTPPQALD LLRRLLVFAP DKRLSAAQAL 300

QHPYVQRFHC PGQEWTRDAA FQLPVPAGVQ LSATEYRNRL YQMLLERRGS GGLGGAAPEP 360

GAAPQEPGRR HRSSGGRAPE RGACCRPRRV PSGLRGPCPD SGSVCPAEAP RAATSKSRQR 420

PAPLLQLPPP GRRARPPAPA AEAPLAPAGV AAPSQGRPAP SLTSQAVAQA ANRALIRSDQ 480

TRVSGLRAAG GLRGSRGPGD APEPRPGRRM LGSTSALQGA QGAARAALGG YSQAYGTVCR 540

SALDCLPLLP RPAP 554

Nucleotide Sequence
(FASTA)

ATGTGCGCCG CCGAGGTGGA CGCTCACATA GCGCGGAGAT TCCGGCTGCA GCGGCGGCTG 60

GGCAAGGGGG CCTACGGCAT TGTTTGGAAG GCAGTGGACC GGAGCACCGG CGAGGTCGTG 120

GCCATCAAGA AGATCTTCGA TGCCTTCAGA GACCAGACGG ATGCCCAGAG GACCTTCCGG 180

GAGATCGTGC TCCTGCAGGA GTTTGGAGGC CACCCCAACA TCATCCGCCT GCTGGACGTG 240

ATCCGAGCCG AGAACGACAG GGACATCTAC CTGGTGTTTG AGTCTATGGA CACGGACCTG 300

CACGCGGTCA TTGAGAAGGG CACGCTGTTG AAAGACATCC ACAAACGCTA CATCTTCTAC 360

CAGCTCCTGC GGGCCACGCA GTTCCTCCAC TCGGGCCACG TCGTCCACCG GGACCAGAAG 420

CCATCCAACG TCCTGCTGGA CGCCAACTGC CTGGTGAAGC TCTGCGACTT TGGCCTGGCC 480

CGGTCGCTGA GCAGTGTCCC CGAGGGGCCC GAGGGCCAGC CGCTGACGGA GTACGTGGCC 540

ACACGCTGGT ACCGGGCGCC GGAGGTGCTG CTGTCCTCAC ACTGGTACAC CCCGGGGGTG 600

GACATGTGGA GCCTGGGCTG CATCCTGGGG GAGATGCTGC GAGGGCGGCC CCTGTTCCCA 660

GGCACGTCCA CGCTGCACCA GCTGCAGCTG ATCCTGGAGG CCGTCCCCCC GCCCTCCGAG 720

GAGGACCTCC TGGCTCTCGG CTCAAACTAC AGTTCCTTGG TCCTGCACCA TCTGGGGTCC 780

CGGCCTCGGC AGCTGCTGGA CGCCCTTCTG CCGCCGGACA CCCCGCCGCA GGCCCTGGAT 840

CTCCTCCGGC GACTGCTGGT GTTCGCCCCG GACAAGCGCC TGAGCGCCGC GCAGGCCCTG 900

CAGCACCCCT ACGTGCAGAG GTTCCACTGC CCCGGCCAGG AGTGGACACG GGATGCGGCC 960

TTTCAGCTTC CGGTGCCCGC AGGGGTCCAG CTCTCTGCGA CTGAGTATCG CAACCGGCTC 1020

TATCAGATGC TGCTGGAGCG CAGGGGCAGC GGCGGCCTGG GGGGCGCAGC CCCTGAACCC 1080

GGAGCGGCCC CGCAGGAGCC GGGACGCAGG CATCGGAGCA GCGGCGGGCG CGCGCCCGAG 1140

CGCGGTGCGT GCTGCCGTCC CCGCCGCGTC CCCAGCGGCT TGCGCGGCCC CTGCCCTGAC 1200

AGCGGCTCTG TCTGCCCCGC AGAGGCCCCC CGCGCCGCCA CGAGCAAGTC CCGGCAGCGC 1260

CCCGCACCCC TGCTCCAACT TCCACCCCCA GGGAGGCGGG CTCGGCCCCC TGCGCCGGCG 1320

GCGGAGGCCC CCTTGGCACC AGCGGGGGTG GCTGCTCCTT CCCAGGGGAG GCCGGCGCCC 1380

TCCCTGACCT CGCAGGCTGT GGCCCAGGCG GCCAACCGGG CCCTGATCCG CAGCGACCAG 1440

ACGCGGGTCA GTGGGCTGCG GGCCGCTGGC GGGCTCCGCG GGAGCCGGGG CCCAGGGGAT 1500

GCCCCGGAGC CTCGGCCGGG CCGCAGGATG CTGGGCAGCA CCTCCGCGCT ACAGGGCGCC 1560

CAGGGCGCTG CCAGGGCTGC GCTCGGGGGC TACTCCCAGG CCTATGGCAC AGTCTGCCGC 1620

TCGGCACTGG ACTGCCTGCC CCTGCTTCCC CGCCCTGCAC CT 1662

Domain Profile

S: 3     slkplgeGaygvvvsavdkrteervaikklsrpfqketsakrtlRElkllkel.kheNii  61

          +++lg+Gayg+v++avd++t+e vaikk++++f+++t+a+rt+RE+ ll+e+  h+Nii

Q: 16    LQRRLGKGAYGIVWKAVDRSTGEVVAIKKIFDAFRDQTDAQRTFREIVLLQEFgGHPNII  75

         6789*************************************************99*****

S: 62    klldvftpeeeleelkdvYlvtelmetdLkkviksq.klsdehiklllyqilrglkylHs  120

         +lldv+++e+     +d+Ylv+e m+tdL++vi++   l+d h ++++yq+lr++++lHs

Q: 76    RLLDVIRAEN----DRDIYLVFESMDTDLHAVIEKGtLLKDIHKRYIFYQLLRATQFLHS  131

         *******999....9********************98899********************

S: 121   anviHrDlKPsNllvnedcelkildFGlarsadkekekk....lteyvatrwYraPeill  176

          +v+HrD+KPsN+l++++c +k++dFGlars ++  e      lteyvatrwYraPe+ll

Q: 132   GHVVHRDQKPSNVLLDANCLVKLCDFGLARSLSSVPEGPegqpLTEYVATRWYRAPEVLL  191

         *******************************887766656778*****************

S: 177   slkeytkavDiWsvGCIlaElltgkplfpgkdeidqlekilevlgtpseeflkkieseea  236

         s++ yt  vD+Ws+GCIl+E+l+g+plfpg+++++ql++ile ++ psee+l ++ s+

Q: 192   SSHWYTPGVDMWSLGCILGEMLRGRPLFPGTSTLHQLQLILEAVPPPSEEDLLALGSNYS  251

         ************************************************************

S: 237   rnyikslpkkkkkdfeelfpk.aseealdLleklLvldpdkRisveeaLehpYl  289

         + ++++l +++++ +++l+p  + ++aldLl++lLv++pdkR+s+++aL+hpY+

Q: 252   SLVLHHLGSRPRQLLDALLPPdTPPQALDLLRRLLVFAPDKRLSAAQALQHPYV  305

         ******************9875889****************************7

Domain Sequence
(FASTA)

LQRRLGKGAY GIVWKAVDRS TGEVVAIKKI FDAFRDQTDA QRTFREIVLL QEFGGHPNII 60

RLLDVIRAEN DRDIYLVFES MDTDLHAVIE KGTLLKDIHK RYIFYQLLRA TQFLHSGHVV 120

HRDQKPSNVL LDANCLVKLC DFGLARSLSS VPEGPEGQPL TEYVATRWYR APEVLLSSHW 180

YTPGVDMWSL GCILGEMLRG RPLFPGTSTL HQLQLILEAV PPPSEEDLLA LGSNYSSLVL 240

HHLGSRPRQL LDALLPPDTP PQALDLLRRL LVFAPDKRLS AAQALQHPYV 290

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004707	; F:MAP kinase activity
GO:0046777	; P:protein autophosphorylation

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR003527	; MAP_kinase_CS.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS01351	; MAPK; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013