EKS-ORC-00189

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORC-00189

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	492.1	4.2E-148	4	295	292

Status

Unreviewed

Ensembl Protein

ENSOCUP00000024107

UniProt Accession

G1U3Z0;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL1

Gene Synonyms/Alias

CDKL1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOCUG00000023744	ENSOCUP00000024107	ENSOCUT00000027548

Organism

Oryctolagus cuniculus

Functional Description

Protein Length

360

Protein Sequence
(FASTA)

MEKYEKIGKI GEGSYGVVFK CRNRDTGQIV AIKRFLESED DPVIKKIALR EIRMLKQLKH 60

PNLVNLLEVF RRKRRLHLVF EYCDHTVLHE LDRHQRGVPE HLVKSITWQT LQAVNFCHTH 120

NCIHRDVKPE NILITKHSVI KLCDFGFARL LTGPSDYYTD YVATRWYRSP ELLVGDTQYG 180

PPVDVWAIGC VFAELMSGVP LWPGKSDVDQ LYLIRKTLAE GDLIPRHQQV FSTNQYFSGV 240

QIPNPEALVC FSTYTKMPSV PFKAVRGASL LSQGCLHMDP AQRLTCEQLL QHPYFDSIRE 300

TRELAKDHDK PTRKNLRQSR KHLPGLQYLP QLTSSSILPA LDKKKYYCNT KKLDYRFPNI 360

Nucleotide Sequence
(FASTA)

ATGGAGAAGT ACGAGAAGAT CGGGAAGATC GGCGAAGGAT CCTATGGCGT CGTTTTCAAA 60

TGCAGAAACA GGGACACGGG CCAGATCGTG GCCATCAAGA GGTTTCTGGA ATCCGAAGAT 120

GACCCTGTCA TAAAGAAAAT CGCCCTTCGG GAAATCCGCA TGCTCAAGCA ACTCAAGCAT 180

CCCAACCTCG TCAACCTCCT GGAAGTGTTC AGGAGGAAGC GGAGGCTTCA CTTGGTGTTC 240

GAGTACTGCG ACCACACGGT GCTCCACGAG CTGGACCGAC ACCAGCGGGG GGTACCAGAA 300

CATCTCGTGA AGAGCATAAC TTGGCAGACA CTGCAGGCCG TGAACTTCTG CCACACCCAC 360

AACTGCATAC ATAGAGATGT GAAACCAGAA AATATCCTCA TCACAAAACA TTCCGTGATT 420

AAGCTTTGTG ACTTTGGATT TGCTCGCTTA TTGACCGGCC CCAGTGACTA CTACACAGAC 480

TATGTGGCTA CCAGGTGGTA CCGCTCCCCC GAGCTGCTGG TGGGAGACAC GCAGTATGGG 540

CCCCCAGTCG ATGTTTGGGC GATTGGCTGT GTGTTTGCGG AACTGATGTC AGGGGTGCCT 600

CTGTGGCCTG GAAAATCAGA TGTGGATCAG CTCTACCTGA TTAGGAAAAC CCTGGCCGAA 660

GGGGATCTCA TTCCCAGGCA CCAGCAAGTC TTCAGCACCA ATCAGTACTT CAGTGGGGTG 720

CAAATTCCCA ACCCTGAAGC GCTGGTGTGT TTCTCTACTT ACACAAAGAT GCCATCAGTA 780

CCATTTAAGG CAGTAAGAGG GGCTTCTCTG CTCTCCCAGG GCTGCCTGCA CATGGACCCT 840

GCTCAGAGGC TGACCTGTGA ACAGCTGTTG CAGCACCCCT ACTTTGACAG CATCCGAGAA 900

ACAAGAGAGC TGGCCAAAGA CCACGACAAA CCAACAAGGA AAAACTTAAG ACAAAGCCGA 960

AAGCACCTGC CTGGGCTGCA GTACTTACCC CAGCTCACGA GCAGCAGCAT CCTTCCGGCT 1020

CTGGATAAGA AGAAGTACTA CTGTAATACG AAGAAACTGG ACTACCGCTT CCCAAACATT 1080

TAA 1083

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         yek+gk+GeGsyGvv+kcrn+dtgqivaik+flesedd+++kkialrei++lkqlkh+nl

Q: 4     YEKIGKIGEGSYGVVFKCRNRDTGQIVAIKRFLESEDDPVIKKIALREIRMLKQLKHPNL  63

         9***********************************************************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnllevfrrk++l+lvfey+d+tvl+el+r+++Gv+e+lvk+i++q+l+a++fch++n+i

Q: 64    VNLLEVFRRKRRLHLVFEYCDHTVLHELDRHQRGVPEHLVKSITWQTLQAVNFCHTHNCI  123

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrd+kpenili+k++v+klcdfGfarll++p+d+ytdyvatrwyr+pellvgdt+yG++v

Q: 124   HRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQYGPPV  183

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktl..GeliprhqkifsknevfaGvklp  238

         dvwaiGc++ael++G pl+pgksdvdqly+irktl  G+liprhq++fs+n++f+Gv++p

Q: 184   DVWAIGCVFAELMSGVPLWPGKSDVDQLYLIRKTLaeGDLIPRHQQVFSTNQYFSGVQIP  243

         **********************************97789*********************

S: 239   evedl..eslekkypklnevlld....llkkclkldpaerlsceellkheyf  284

         ++e l   s  +k+p++   ++     l ++cl++dpa+rl+ce+ll+h+yf

Q: 244   NPEALvcFSTYTKMPSVPFKAVRgaslLSQGCLHMDPAQRLTCEQLLQHPYF  295

         ***9833345678886654443222226789********************9

Domain Sequence
(FASTA)

YEKIGKIGEG SYGVVFKCRN RDTGQIVAIK RFLESEDDPV IKKIALREIR MLKQLKHPNL 60

VNLLEVFRRK RRLHLVFEYC DHTVLHELDR HQRGVPEHLV KSITWQTLQA VNFCHTHNCI 120

HRDVKPENIL ITKHSVIKLC DFGFARLLTG PSDYYTDYVA TRWYRSPELL VGDTQYGPPV 180

DVWAIGCVFA ELMSGVPLWP GKSDVDQLYL IRKTLAEGDL IPRHQQVFST NQYFSGVQIP 240

NPEALVCFST YTKMPSVPFK AVRGASLLSQ GCLHMDPAQR LTCEQLLQHP YF 292

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013