EPS-ORC-00056

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-ORC-00056

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/PTEN	260.9	9.2E-78	148	323	176

Status

Unreviewed

Ensembl Protein

ENSOCUP00000024287

UniProt Accession

G1U4G6;

Protein Name

Protein Synonyms/Alias

Gene Name

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOCUG00000024145	ENSOCUP00000024287	ENSOCUT00000025349

Organism

Oryctolagus cuniculus

Functional Description

Protein Length

464

Protein Sequence
(FASTA)

SRIKNIARLI VSSFAFRVFG ILLIFVDIFL IMSDVLFNEN TMVLELRSAS LAIALFFCFD 60

VLLSVYVEGR KQYFSDLFNT LDAVIIAITL VIDIIYFFFE LRILKDIPRL AVLLRPLRLV 120

ILIRVFHLAY QKRQLEKLTR RLVSGNKRRY NRDGFDLDLT YVTDRIIAMS FPSSGKQSFY 180

RNPIKEVVKF LDTKHPNHYR VYNLCSEKAY DPEYFHNRVQ RIMIDDHNVP TLSEMVVFAK 240

EVNMWLAQDK ENVVVIHCKG GKGRTGTMVC VCLIANQLFG TAEDSLSFFG HQRIDQTTST 300

KYHGVETPSQ HRYVGYFEKV KRLHHWTLPP RKILQPNKII IHSIHSVGKG DGSDLKIQII 360

TMQQTVFSCS SSKNCKIFHD VETDRVIIEL LNCPILYDDV KVRFLSRNLP KYYDKCAFFF 420

WFNTAFIQNN RLYLRRNELD NPHKRKAWKT YGPRFAVEIY FNTT 464

Nucleotide Sequence
(FASTA)

AGCAGGATAA AGAACATTGC TCGCTTAATT GTATCATCCT TTGCATTCAG AGTATTTGGA 60

ATTCTACTCA TATTTGTGGA TATATTTCTC ATCATGTCAG ATGTACTTTT CAACGAAAAC 120

ACAATGGTTT TGGAATTGCG TTCAGCTTCT TTGGCTATTG CACTCTTTTT TTGCTTTGAT 180

GTTTTACTCA GCGTATATGT TGAGGGGAGG AAGCAATATT TTTCTGATCT ATTTAACACC 240

TTAGATGCTG TCATTATTGC GATAACTCTC GTGATTGATA TCATTTACTT CTTTTTTGAG 300

CTAAGAATTC TGAAAGACAT ACCAAGGCTG GCTGTTCTGC TTCGACCTCT ACGCCTTGTA 360

ATTTTGATAA GAGTTTTCCA TCTGGCTTAT CAAAAAAGAC AACTTGAAAA GCTGACCAGA 420

AGATTGGTTT CAGGAAACAA AAGGAGATAC AACAGAGATG GATTTGACCT GGATCTCACT 480

TACGTAACTG ATCGCATAAT TGCCATGTCA TTTCCATCTT CTGGTAAACA GTCTTTCTAC 540

AGGAATCCAA TTAAGGAAGT TGTGAAGTTC CTGGATACCA AACATCCAAA CCACTACCGA 600

GTCTACAATC TGTGCAGTGA AAAAGCTTAC GATCCTGAAT ATTTTCATAA CAGAGTCCAA 660

AGAATCATGA TTGATGATCA TAACGTCCCT ACTCTCAGTG AGATGGTGGT GTTTGCCAAA 720

GAAGTAAATA TGTGGCTGGC TCAAGACAAG GAAAATGTCG TAGTGATTCA CTGCAAAGGC 780

GGCAAAGGGA GAACTGGGAC CATGGTCTGT GTTTGTCTCA TTGCTAATCA GCTCTTTGGT 840

ACTGCAGAGG ATAGTCTTTC ATTCTTTGGA CATCAACGAA TAGATCAAAC CACCAGCACC 900

AAATATCACG GAGTGGAAAC TCCCTCTCAA CATAGATATG TAGGCTACTT TGAAAAGGTG 960

AAGCGTCTCC ACCACTGGAC TCTCCCACCC AGAAAAATCC TCCAGCCAAA CAAAATCATC 1020

ATTCATTCAA TTCATAGTGT TGGGAAAGGT GATGGAAGTG ACCTAAAAAT TCAAATTATA 1080

ACAATGCAAC AGACAGTCTT TTCATGCTCA TCTTCTAAGA ACTGTAAGAT ATTTCATGAT 1140

GTCGAAACTG ACAGAGTCAT TATTGAATTG TTGAACTGTC CCATCTTATA TGATGACGTT 1200

AAAGTCAGAT TTCTCTCTCG GAATCTCCCC AAATACTATG ACAAATGTGC ATTCTTCTTC 1260

TGGTTCAATA CAGCTTTCAT ACAAAACAAC AGGCTATATC TAAGACGAAA TGAATTGGAT 1320

AACCCACACA AACGAAAAGC CTGGAAAACC TATGGCCCAC GTTTCGCAGT TGAGATTTAT 1380

TTCAATACTA CATGA 1395

Domain Profile

S: 1     rrltedgfdldltyvteriiavsfPaeareevyrnnlrevvrlldskhrnkyklynlcse  60

         rr+ +dgfdldltyvt+riia+sfP+++++++yrn+++evv++ld kh n+y++ynlcse

Q: 148   RRYNRDGFDLDLTYVTDRIIAMSFPSSGKQSFYRNPIKEVVKFLDTKHPNHYRVYNLCSE  207

         79**********************************************************

S: 61    rrydltklnakvaefgiedlnaPaleklvsickeldeWlseddenvvvlhckggkgrlGv  120

         ++yd++ ++++v++++i+d+n+P+l ++v+++ke++ Wl++d+envvv+hckggkgr+G+

Q: 208   KAYDPEYFHNRVQRIMIDDHNVPTLSEMVVFAKEVNMWLAQDKENVVVIHCKGGKGRTGT  267

         ************************************************************

S: 121   ivcayllaseisakadealdtfgerr...tredkvagvkqPsqrryvsyfsqllkg  173

         +vc  l+a++ + +a+++l +fg +r   t++ k  gv++Psq+ryv yf +++++

Q: 268   MVCVCLIANQLFGTAEDSLSFFGHQRidqTTSTKYHGVETPSQHRYVGYFEKVKRL  323

         *************************999999*********************9976

Domain Sequence
(FASTA)

RRYNRDGFDL DLTYVTDRII AMSFPSSGKQ SFYRNPIKEV VKFLDTKHPN HYRVYNLCSE 60

KAYDPEYFHN RVQRIMIDDH NVPTLSEMVV FAKEVNMWLA QDKENVVVIH CKGGKGRTGT 120

MVCVCLIANQ LFGTAEDSLS FFGHQRIDQT TSTKYHGVET PSQHRYVGYF EKVKRL 176

Keyword

Complete proteome; Hydrolase; Ion transport; Ionic channel; Membrane; Protein phosphatase; Reference proteome; Transmembrane; Transport.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Oreochromis niloticus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>

Gene Ontology

GO:0016021	; C:integral to membrane
GO:0005216	; F:ion channel activity
GO:0004725	; F:protein tyrosine phosphatase activity
GO:0035335	; P:peptidyl-tyrosine dephosphorylation

KEGG

InterPros

IPR008973	; C2_Ca/lipid-bd_dom_CaLB.
IPR005821	; Ion_trans_dom.
IPR014019	; Phosphatase_tensin-typ.
IPR014020	; Tensin_phosphatase_C2-dom.
IPR016130	; Tyr_Pase_AS.
IPR000242	; Tyr_Pase_rcpt/non-rcpt.

Pfam

PF00520	; Ion_trans; 1.
PF10409	; PTEN_C2; 1.
PF00102	; Y_phosphatase; 1.

SMARTs

Prosites

PS51182	; C2_TENSIN; 1.
PS51181	; PPASE_TENSIN; 1.
PS00383	; TYR_PHOSPHATASE_1; 1.

Prints

Created Date

20-Feb-2013