EKS-OTG-00095

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-OTG-00095

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/PIKK	450.6	3.5E-135	2291	2617	327

Status

Unreviewed

Ensembl Protein

ENSOGAP00000000152

UniProt Accession

H0WFW3;

Protein Name

Protein Synonyms/Alias

Gene Name

ATR

Gene Synonyms/Alias

ATR;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000000171	ENSOGAP00000000152	ENSOGAT00000000171

Organism

Otolemur garnettii

Functional Description

Protein Length

2642

Protein Sequence
(FASTA)

MGEHGLELAS MIPALRELGS AAPEDYNTVV QKPRQILCQF IDRILTDVNV VALELIKKTD 60

SQPTSVMLLD FIQHIMKSSP LMFVNVNGSH GQNEAKSSCI EFSNWIITRL LRIAATPSCH 120

MLHKKICEVI CSLLFLFKSK SPSIFGVLTK ELLHLFEDLI YLHRRNAVGH VEWPVVVTRF 180

LSQLDEHMEY LQPAPLQFMS MQNLEFIEVT LLTVLIRIIA IVFFRRQELL LWQIGCVLLE 240

YGSPKIKSLA MSLLTKLFEL GGLPAQPAST FFSSFLGLLK SLVEVDTDQL KLYEEPLSKL 300

IKTLFPFEAE AYRNIEPVYL NMLLERLCVI FEDGVLMRLK SDLLKAALCH ILQYFLKFVP 360

AGYESALHVR KGYVRNICRA LVDVLGIQVD AGYLLGPLYA ALKIESMEII EEIECQTQQE 420

NLSSNIDGIS PKRRRLSSSL NSLKRASKQT EEIKHVDMSK KSILWSALKQ KAESLQISLE 480

CSSLKNPVIE TLEGIAVVLQ LTALCTIHCS HQNVACHNFK DFEHKSKKKL SIVITWMPLD 540

FYTRVLKSCR SLLESIQKPD LEAIIDNVVK IYDALIYMQV KSSFEDHILE ELCGMLSIPW 600

IYSHSDDCLK LTTFATGLLT LSQRISDSYS PQAQSRCVFL LTLLPRGIFL EWRTAVYNWA 660

LQSSYEVIRA SCVNGFFILL QQQNSCNRVP KILIDKVKDD SDIVKKEFAS ILGQLVCTLH 720

GMFYLTSSLI EPFSEHGHVD LFCKNLKATS QHECSSSRLK ASICKPFLFL LKKNTPSPVK 780

LAFIDNLPHL CKHLDFREDE TDVKAVLGTL LNLMEDPDKD VRVAFSGNIK HVLGSLDSED 840

GFIKELFVLR MKEAYTHAQI SRNNELKDTL ILTTGDIGRA AKGDLVPFAL LHLLHCLLSK 900

SASVSGAAYT EIRALVAAKS VKLQNFFSQY KKPICQFLVE SLHSSQMAAL PSTPFQNAEI 960

RKQDVAHQRE MALNTLSEIA NVFDFPDLNR FLTRTLQVLL PDLAAKASPA ASALIRTLGK 1020

QLNVNRREIL INNFKYIFSH LVCSCSKDEL ERALHYLKNE TEIELGSLLR QDFQGLHNEL 1080

LLRIGEHYQQ VFNGLSILAS FASSDDPYQG PRDITSPELM ANYLQPKLLG ILAFFNMQLL 1140

SSSVGIEDKK MALNSLMSLM KLMGPKHVSS VRVKMMTTLR TGLRFKDDFP ELCCRAWDCF 1200

VRCLDHACLG SLLSHVIVAL LPLIHIQPKE TAAIFHYLII ENRDAVQDFL HEIYFLPDHP 1260

ELKKIKAVLQ EYRKETSEST DLQTTLQLSM KAIQHENVDV RIHALTSLKE TLYKNQEELI 1320

KYATDSETVE PIISQLVTVL LKGCQDANSQ ARLLCGECLG ELGAIDPGRL DFSTTETQGK 1380

DFTFVTGVED LTFAYGLLME LTRAYLAYAD NSRAQDSAAY AIQELLSIYE CREMETDGPG 1440

HQLWKRFPEH VREILEPHLN TRYKSSQKST DWSGVKKPIY LSELGNNFAE WSASWAGYLI 1500

TKVRHELASK IFTCCSIMMK HDFKVTIYLL PHILVYVLLG CNQEDQQEVY AEIMAVLKHD 1560

DQHTISTQDS ASDLCQLSTQ TVFSMLDHLA QWARHKFQAL NAEKFAQSKS NRDKVNSMVA 1620

SADHEDYQSV TRFLDLIPQD TLAVASFRSR AYTRAVMHFE SFITEKKQNI QEHLGFLQKL 1680

YAAMHEPDGV AGVSTIRKAE PSLKEQILEH ESIGLLRDAT ACYDRAIQLE PDQIIHYHGV 1740

VKSMLGLGQL STVITQVNGV HANRSEWTDE LNTYRVEAAW KLSQWDLVES YLAEDGKSTT 1800

WSVRLGQLLL SAKKRDITAF YNTLKLVRTE QIVPLSAASF ERGSYQRGYE YIVRLHMLCE 1860

LEHSTKPLFH QSPGDSSQED SLNWVARLEM TQNSYRAKEP ILALRRALLS LNKRPDYNEM 1920

VGECWLQSAR VARKAGHHQT AYNAILNAGE SRLAELYVEK AKWLWSKGDV HQALMVLQKG 1980

VELCFPENKT PTDNKNMLIH GRATLLVGRF MEETANFESN AIMKKYKDVT VVLPEWEDGH 2040

FYLAKYYDKL MPMVTDNKME KQGDLIRYIV LHFGRSLQYG NQFIYQSMPR MLSLWLDFGS 2100

KAYECEKACR CDRIQMRNDL GKINKVITEH TNYLAPYQFL TAFSQLISRI CHSHDEVFVV 2160

LMEIIAKVFL AYPQQAMWMM TAVSKSSYPM RVNRCKEILN KAIEMKKSLE KFVGDATRLT 2220

DKLLELCNKS VDGNSSTLSM STHFKMLKKL VEESTFSEIL IPLQSVMIPT LPSVLGAHAN 2280

HDPFPGHWAY IAGFDDTVEI LASLQKPKKI SLKGSDGKFY IMMCKPKDDL RKDCRLMEFN 2340

SLINKCLRKD AESRRRELHI RTYAVIPLND ECGIIEWVNN TAGLRPILTK LYKERGVYMT 2400

GKELRQCMLP KAAALSEKLK IFREFLLPRH PPVFHEWFLR TFPDPTSWYS SRSAYCRSTA 2460

VMSMVGYILG LGDRHGENIL FDSLTGECVH VDFNCLFNKG ETFEVPEIVP FRLTHNMVNG 2520

MGPMGTEGLF RRACEVTLRL MRDQSEPLMS VLKTFLHDPL VEWSKPVKGH SKAQLNETGE 2580

VVNEKAKTHV LDIEQRLQGI IKTRNRVTGL PLSIEGHVHY LIQEATDENL LCQMYLGWTP 2640

YM 2642

Nucleotide Sequence
(FASTA)

ATGGGCGAGC ATGGCCTGGA GCTGGCTTCC ATGATCCCCG CCCTGCGGGA GCTGGGCAGT 60

GCTGCTCCAG AGGACTATAA TACAGTTGTA CAGAAGCCAA GACAAATTCT ATGTCAGTTC 120

ATTGACCGAA TACTTACAGA TGTAAATGTT GTTGCTCTAG AACTTATAAA GAAAACTGAC 180

TCTCAGCCAA CCTCTGTGAT GTTACTTGAC TTCATTCAGC ATATTATGAA ATCCTCCCCA 240

CTTATGTTTG TAAATGTAAA TGGAAGCCAT GGGCAGAATG AGGCCAAAAG CAGTTGTATT 300

GAATTCAGTA ATTGGATCAT AACAAGACTT CTACGGATTG CAGCCACTCC ATCTTGTCAC 360

ATGTTACATA AGAAAATTTG TGAAGTCATC TGCTCGTTAT TATTTCTTTT TAAAAGCAAG 420

AGTCCTTCTA TTTTTGGAGT ACTCACAAAG GAATTATTAC ATCTTTTTGA AGACTTGATT 480

TACCTCCACA GAAGAAACGC AGTGGGACAT GTGGAATGGC CAGTGGTTGT TACCCGATTT 540

TTAAGTCAAT TAGATGAACA CATGGAATAT TTACAACCAG CACCTTTGCA GTTCATGAGC 600

ATGCAAAATT TAGAATTTAT TGAAGTCACT TTATTAACAG TTCTTATTCG TATTATTGCA 660

ATTGTGTTTT TTAGAAGGCA AGAACTCCTA CTTTGGCAGA TAGGTTGTGT TCTGCTAGAG 720

TATGGTAGTC CAAAAATTAA ATCCTTAGCA ATGAGCCTTT TAACTAAACT TTTTGAGCTT 780

GGAGGCCTAC CAGCGCAACC AGCCAGTACC TTTTTCAGCT CCTTTTTAGG ATTATTGAAA 840

AGCCTTGTAG AAGTGGATAC TGACCAGTTG AAACTCTATG AAGAGCCATT ATCAAAGCTG 900

ATAAAGACAC TATTTCCCTT TGAAGCAGAA GCTTATAGAA ATATTGAACC TGTCTATTTA 960

AATATGCTGC TGGAAAGACT CTGTGTCATT TTTGAAGATG GTGTGCTTAT GCGGCTTAAG 1020

TCTGATTTGC TAAAAGCAGC TTTGTGCCAT ATACTGCAGT ATTTCCTTAA ATTTGTGCCA 1080

GCTGGATATG AATCTGCTTT ACATGTCAGG AAGGGCTATG TGAGAAATAT TTGCAGAGCT 1140

CTTGTGGATG TGCTTGGAAT TCAGGTAGAT GCAGGGTACT TATTGGGCCC ACTGTATGCA 1200

GCCTTGAAAA TAGAAAGTAT GGAAATCATT GAGGAGATTG AATGCCAAAC TCAACAAGAA 1260

AACCTCAGCA GTAATATTGA TGGAATATCA CCCAAAAGGC GTCGACTCAG CTCATCTCTA 1320

AACTCTTTAA AAAGAGCATC AAAACAGACT GAAGAAATTA AACATGTGGA TATGAGCAAA 1380

AAGAGCATAT TATGGAGTGC ACTGAAACAG AAAGCTGAAT CCCTTCAGAT TTCCCTTGAA 1440

TGCAGCAGCC TAAAGAATCC TGTTATTGAG ACTTTAGAAG GAATCGCTGT TGTCCTACAA 1500

CTGACTGCTC TCTGTACTAT TCACTGTTCT CATCAAAATG TGGCCTGCCA TAATTTCAAG 1560

GACTTTGAGC ACAAATCTAA GAAGAAACTG TCAATAGTGA TAACTTGGAT GCCATTGGAT 1620

TTTTACACAA GAGTGCTAAA GAGCTGCAGG AGTTTGTTAG AATCTATTCA GAAACCTGAC 1680

CTAGAGGCAA TCATTGATAA TGTGGTGAAA ATTTATGATG CATTGATTTA CATGCAAGTA 1740

AAAAGTTCAT TTGAAGATCA TATTCTGGAA GAGCTGTGTG GCATGCTCTC AATTCCATGG 1800

ATTTATTCCC ATTCTGATGA CTGTTTAAAG TTGACCACAT TTGCCACTGG TCTTCTAACA 1860

TTAAGCCAGA GGATTTCAGA TAGCTACTCA CCCCAGGCAC AGTCACGGTG TGTATTTCTT 1920

CTAACTCTGC TTCCAAGAGG GATATTCCTT GAATGGAGAA CAGCAGTTTA CAACTGGGCC 1980

CTGCAGAGCT CCTATGAAGT AATCCGGGCT AGTTGTGTTA ATGGATTTTT TATCTTACTG 2040

CAGCAGCAGA ATTCTTGTAA CAGAGTTCCC AAGATCCTTA TAGATAAAGT TAAAGATGAT 2100

TCTGACATTG TCAAGAAAGA ATTTGCCTCT ATACTTGGTC AACTTGTCTG CACTCTCCAT 2160

GGCATGTTTT ATTTGACAAG TTCCTTAATA GAACCTTTCT CTGAACATGG GCATGTGGAC 2220

CTCTTCTGTA AGAATTTAAA AGCCACTTCT CAACATGAAT GTTCATCTTC TCGATTAAAA 2280

GCTTCTATTT GCAAGCCATT CCTTTTCCTA TTGAAAAAAA ATACACCTAG TCCAGTAAAA 2340

CTTGCTTTCA TAGATAACCT ACCTCATCTT TGTAAGCATC TTGATTTTAG AGAAGATGAA 2400

ACGGATGTAA AAGCTGTTCT CGGAACTTTA TTAAATTTAA TGGAAGATCC AGACAAGGAT 2460

GTTAGAGTGG CTTTTAGTGG AAATATCAAG CATGTATTGG GATCCTTGGA CTCTGAAGAT 2520

GGATTTATAA AAGAGCTTTT TGTGTTAAGA ATGAAGGAAG CATATACACA TGCCCAAATA 2580

TCAAGAAATA ATGAGTTGAA GGATACCTTG ATTCTTACAA CAGGGGATAT TGGAAGGGCA 2640

GCAAAAGGAG ATTTGGTACC TTTTGCACTC TTGCATTTAT TGCATTGTTT GTTATCCAAG 2700

TCAGCATCTG TGTCTGGAGC AGCATACACA GAAATTAGAG CTCTGGTTGC AGCTAAAAGT 2760

GTTAAATTGC AAAATTTTTT TAGCCAATAT AAAAAACCCA TCTGTCAGTT CTTGGTAGAA 2820

TCCCTCCACT CCAGTCAGAT GGCAGCACTT CCTAGTACTC CATTCCAGAA TGCGGAGATA 2880

AGAAAACAAG ATGTAGCACA CCAGAGAGAA ATGGCTTTAA ATACCTTGTC TGAAATTGCC 2940

AATGTTTTTG ACTTTCCTGA TCTTAATCGT TTTCTTACTA GGACTTTACA AGTTCTACTA 3000

CCTGATCTTG CTGCCAAAGC AAGCCCTGCA GCTTCTGCTC TCATTCGAAC TTTAGGAAAA 3060

CAACTAAATG TCAATCGTAG AGAGATTTTA ATAAATAACT TCAAATATAT TTTTTCCCAT 3120

TTGGTTTGTT CCTGTTCTAA AGATGAATTA GAACGTGCCC TTCATTATCT GAAGAATGAA 3180

ACAGAAATTG AACTGGGGAG CCTTTTGAGA CAAGATTTCC AGGGATTGCA TAATGAATTA 3240

TTGCTACGTA TTGGAGAACA CTATCAACAG GTTTTCAACG GTTTGTCAAT TCTTGCTTCA 3300

TTTGCATCTA GTGATGATCC ATATCAGGGC CCAAGAGATA TCACATCACC TGAATTGATG 3360

GCTAATTATT TACAACCCAA GTTGTTGGGA ATTTTGGCCT TTTTTAACAT GCAGCTACTG 3420

AGCTCCAGTG TTGGCATTGA AGATAAGAAA ATGGCCTTGA ACAGTTTGAT GTCCTTGATG 3480

AAGTTAATGG GACCCAAACA CGTCAGTTCT GTGAGAGTGA AGATGATGAC CACGCTGAGA 3540

ACTGGCCTTC GATTCAAGGA TGATTTTCCT GAATTGTGTT GCAGAGCTTG GGACTGCTTT 3600

GTTCGTTGCC TGGATCACGC TTGTCTAGGC TCCCTTCTCA GTCATGTAAT AGTAGCATTG 3660

TTACCTCTTA TACACATCCA GCCGAAAGAA ACTGCAGCTA TCTTTCACTA CCTCATAATT 3720

GAAAACAGGG ATGCTGTGCA AGATTTTCTT CATGAAATAT ATTTTTTACC TGATCATCCA 3780

GAATTAAAAA AGATAAAAGC AGTTCTCCAG GAATACAGAA AGGAGACTTC TGAGAGTACT 3840

GATCTTCAAA CAACTCTTCA GCTATCTATG AAGGCAATTC AGCATGAAAA TGTAGATGTT 3900

CGTATTCATG CTCTTACAAG CTTGAAGGAG ACCTTATATA AAAATCAGGA AGAACTGATA 3960

AAATATGCAA CAGATAGTGA AACAGTAGAA CCTATTATCT CACAGTTGGT GACAGTGCTT 4020

CTGAAAGGTT GCCAAGATGC AAACTCTCAA GCTCGACTAC TCTGTGGGGA ATGCTTAGGG 4080

GAGTTGGGGG CAATAGATCC AGGTCGATTA GATTTCTCAA CGACTGAAAC CCAAGGAAAA 4140

GATTTTACAT TTGTGACTGG AGTAGAAGAT TTAACCTTTG CCTATGGATT ATTGATGGAA 4200

CTGACAAGAG CTTACCTTGC ATATGCAGAT AACAGCCGAG CCCAAGATTC AGCTGCTTAT 4260

GCCATTCAAG AGTTACTTTC TATATATGAA TGTAGAGAGA TGGAGACTGA TGGCCCAGGT 4320

CACCAATTGT GGAAGAGATT TCCTGAGCAT GTTCGAGAAA TACTAGAACC TCATCTAAAT 4380

ACTAGATATA AGAGCTCTCA GAAGTCAACA GATTGGTCTG GAGTAAAGAA GCCAATTTAC 4440

TTAAGTGAAT TAGGTAATAA CTTTGCAGAA TGGTCCGCAT CTTGGGCAGG TTATCTCATA 4500

ACAAAGGTTC GGCATGAACT TGCCAGTAAA ATCTTCACCT GCTGTAGCAT TATGATGAAG 4560

CATGATTTCA AGGTGACCAT CTATCTTCTT CCACATATTT TGGTGTATGT CTTGTTGGGT 4620

TGTAATCAAG AAGATCAGCA GGAGGTCTAT GCAGAAATTA TGGCAGTTCT AAAGCATGAT 4680

GACCAGCATA CCATAAGTAC CCAAGATAGT GCATCTGATC TGTGTCAACT TAGTACACAG 4740

ACCGTGTTCT CCATGCTTGA CCATCTCGCA CAATGGGCAA GACACAAATT TCAGGCGCTG 4800

AATGCAGAGA AATTTGCACA AAGCAAATCA AACAGAGATA AGGTAAACTC AATGGTAGCG 4860

TCTGCAGATC ATGAAGACTA TCAGAGTGTA ACTCGTTTTC TAGACCTCAT ACCTCAGGAT 4920

ACTCTGGCAG TGGCTTCTTT TCGCTCCAGA GCATACACAC GAGCTGTAAT GCACTTCGAA 4980

TCATTTATTA CAGAAAAGAA GCAAAATATT CAAGAACATC TCGGATTTTT ACAGAAACTG 5040

TATGCTGCTA TGCATGAACC AGATGGAGTA GCTGGAGTAA GTACGATTCG AAAAGCAGAA 5100

CCATCTCTTA AAGAACAGAT CCTTGAACAT GAAAGCATTG GTTTGCTGAG GGATGCCACT 5160

GCCTGTTATG ACAGAGCTAT TCAGCTAGAA CCAGACCAGA TCATTCATTA TCATGGTGTA 5220

GTAAAGTCCA TGTTAGGTCT TGGTCAGCTG TCTACTGTAA TCACTCAGGT GAATGGAGTG 5280

CATGCTAACA GGTCTGAATG GACAGATGAA TTAAATACAT ACAGAGTAGA AGCGGCTTGG 5340

AAATTGTCAC AGTGGGATTT GGTGGAAAGC TATTTGGCAG AAGATGGGAA ATCTACAACA 5400

TGGAGTGTCA GGCTGGGCCA GCTATTATTA TCAGCCAAAA AAAGAGATAT TACGGCTTTT 5460

TATAACACAT TGAAACTAGT GAGAACAGAA CAAATTGTAC CTCTTTCAGC TGCTAGCTTT 5520

GAAAGAGGCT CTTACCAACG AGGATATGAA TATATTGTAA GATTGCACAT GTTGTGTGAG 5580

TTGGAGCATA GCACAAAACC ACTTTTTCAC CAATCTCCAG GTGACAGTTC TCAAGAAGAT 5640

TCTCTAAACT GGGTAGCTCG ACTAGAAATG ACCCAGAATT CTTACAGAGC CAAGGAGCCT 5700

ATCCTGGCTC TCCGGAGGGC TTTATTAAGC CTCAACAAAA GACCAGATTA TAATGAAATG 5760

GTTGGAGAAT GCTGGCTACA AAGTGCCAGA GTAGCCAGAA AGGCAGGTCA CCACCAGACA 5820

GCTTATAATG CTATCCTTAA TGCAGGGGAA TCACGACTTG CTGAACTGTA TGTGGAAAAG 5880

GCAAAGTGGC TGTGGTCCAA GGGTGATGTT CACCAGGCAC TAATGGTTCT TCAAAAAGGT 5940

GTTGAATTAT GTTTTCCTGA AAATAAAACC CCAACTGACA ATAAGAACAT GTTAATACAT 6000

GGTCGAGCTA CACTACTGGT AGGCCGATTT ATGGAAGAAA CAGCTAACTT TGAAAGCAAT 6060

GCAATTATGA AAAAATATAA GGATGTGACC GTAGTCCTGC CAGAGTGGGA AGATGGGCAT 6120

TTTTACCTTG CTAAGTACTA TGACAAATTG ATGCCCATGG TCACAGACAA CAAAATGGAA 6180

AAACAGGGTG ATCTTATCCG GTATATAGTT CTTCATTTTG GAAGGTCTCT GCAATATGGA 6240

AATCAATTCA TATATCAATC AATGCCACGA ATGTTATCAC TCTGGCTTGA TTTTGGTTCA 6300

AAGGCATATG AATGTGAAAA AGCTTGTCGC TGTGATCGCA TACAAATGAG AAATGATTTA 6360

GGTAAAATAA ACAAGGTTAT CACAGAGCAC ACAAATTATT TAGCTCCTTA TCAGTTTTTG 6420

ACTGCTTTTT CGCAATTGAT CTCTCGAATT TGTCATTCAC ATGATGAAGT TTTTGTTGTC 6480

CTGATGGAAA TAATAGCCAA AGTATTTCTA GCTTATCCTC AACAAGCAAT GTGGATGATG 6540

ACAGCTGTGT CAAAGTCTTC TTATCCCATG CGTGTGAACA GATGCAAGGA AATTCTAAAT 6600

AAAGCTATTG AGATGAAAAA ATCTTTAGAG AAGTTTGTTG GAGATGCAAC TCGCCTAACA 6660

GATAAGCTTC TAGAATTGTG CAATAAATCG GTTGATGGAA ATAGTTCCAC ATTAAGTATG 6720

AGTACTCACT TTAAAATGCT TAAAAAGCTG GTAGAAGAAT CAACATTTAG TGAAATCCTT 6780

ATTCCTTTGC AATCAGTCAT GATACCTACT CTTCCATCAG TTCTGGGTGC CCATGCTAAC 6840

CATGATCCAT TTCCTGGGCA CTGGGCCTAT ATTGCAGGCT TTGATGATAC GGTAGAAATT 6900

CTTGCTTCTC TTCAGAAACC AAAGAAGATC TCTTTAAAAG GGTCAGATGG AAAGTTCTAC 6960

ATCATGATGT GTAAGCCGAA AGATGACCTG AGAAAGGATT GCAGACTAAT GGAATTCAAT 7020

TCTTTGATTA ATAAGTGCTT AAGAAAAGAT GCCGAATCTC GTAGAAGAGA ACTTCATATC 7080

CGAACATATG CAGTTATTCC GCTAAATGAC GAATGTGGGA TTATTGAATG GGTGAACAAC 7140

ACTGCTGGTT TGAGACCTAT TCTGACCAAA CTGTATAAGG AAAGGGGAGT GTATATGACA 7200

GGAAAGGAAC TTCGCCAGTG TATGCTACCA AAGGCAGCAG CTTTGTCTGA AAAACTCAAA 7260

ATATTCCGAG AATTTCTCCT TCCTAGGCAT CCTCCTGTTT TTCATGAGTG GTTTCTGAGA 7320

ACATTCCCTG ATCCTACATC ATGGTACAGT AGTAGATCAG CATACTGCCG TTCCACTGCA 7380

GTAATGTCAA TGGTTGGTTA TATCTTGGGG CTTGGAGACC GTCATGGTGA AAACATTCTC 7440

TTTGATTCTT TGACTGGTGA ATGTGTACAT GTGGATTTCA ACTGTCTTTT CAATAAGGGA 7500

GAAACCTTTG AAGTTCCAGA AATTGTACCA TTTCGCTTAA CTCACAATAT GGTTAATGGA 7560

ATGGGTCCTA TGGGAACAGA GGGTCTTTTT CGAAGAGCAT GTGAAGTTAC CTTGAGGCTG 7620

ATGAGAGATC AGAGCGAGCC TTTAATGAGC GTCTTAAAGA CTTTTCTGCA TGATCCTCTT 7680

GTGGAGTGGA GTAAACCAGT GAAAGGGCAT TCCAAAGCGC AACTGAATGA AACTGGGGAA 7740

GTTGTCAATG AAAAGGCCAA GACCCATGTT CTTGACATTG AGCAGCGACT ACAAGGTATC 7800

ATCAAGACCC GAAATAGAGT GACAGGGCTG CCGTTATCTA TTGAAGGACA TGTGCATTAC 7860

CTTATACAAG AAGCTACTGA TGAAAACTTA CTATGCCAAA TGTACCTTGG TTGGACCCCA 7920

TATATGTGA 7929

Domain Profile

S: 1     iagfderveilaskqkpkklllrGsdgkeypyLvkgkeDlrqdervlqlfslvNtlLakd  60

         iagfd++veilas+qkpkk++l+Gsdgk+y++++k+k+Dlr+d+r+++++sl+N++L+kd

Q: 2291  IAGFDDTVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKCLRKD  2350

         89**********************************************************

S: 61    ketsrrkLkirtykVvplstrsgliewventvsLkellkklvekkavlldqpisyrykdl  120

         +e++rr+L+irty+V+pl++++g+iewv+nt++L+ +l+kl+++++v++        + +

Q: 2351  AESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKERGVYM--------TGK  2402

         *************************************************........599

S: 121   stvqarkpklkhlklslevfkevlenlvpkdllkklllekfpspeewfelrkaytrslAv  180

         + +q++ pk+++l+++l++f+e+l +++p+ ++++++l++fp+p++w+++r+ay+rs+Av

Q: 2403  ELRQCMLPKAAALSEKLKIFREFLLPRHPP-VFHEWFLRTFPDPTSWYSSRSAYCRSTAV  2461

         *****************************8.*****************************

S: 181   islvgyiLgLgdrhlenllidqetgevvhidfgvafekaktqlkvpekvPFRLTrnivna  240

         +s+vgyiLgLgdrh en+l+d+ tge+vh+df++ f+k++t ++vpe+vPFRLT+n+vn+

Q: 2462  MSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKGET-FEVPEIVPFRLTHNMVNG  2520

         *****************************************.******************

S: 241   lgvtgveGvfrasceavlrvlreskeklltiLevflydplvdwkk.....kkktsketee  295

         +g++g+eG+fr++ce +lr++r++ e l+++L++fl+dplv+w+k     +k++ +et+e

Q: 2521  MGPMGTEGLFRRACEVTLRLMRDQSEPLMSVLKTFLHDPLVEWSKpvkghSKAQLNETGE  2580

         *************************************************99*********

S: 296   elaekakaealkikkllskvekaenavatrdllllee  332

         +++ekak++ l+i+++l+++ k++n+v+ ++l+++++

Q: 2581  VVNEKAKTHVLDIEQRLQGIIKTRNRVTGLPLSIEGH  2617

         ********************************99987

Domain Sequence
(FASTA)

IAGFDDTVEI LASLQKPKKI SLKGSDGKFY IMMCKPKDDL RKDCRLMEFN SLINKCLRKD 60

AESRRRELHI RTYAVIPLND ECGIIEWVNN TAGLRPILTK LYKERGVYMT GKELRQCMLP 120

KAAALSEKLK IFREFLLPRH PPVFHEWFLR TFPDPTSWYS SRSAYCRSTA VMSMVGYILG 180

LGDRHGENIL FDSLTGECVH VDFNCLFNKG ETFEVPEIVP FRLTHNMVNG MGPMGTEGLF 240

RRACEVTLRL MRDQSEPLMS VLKTFLHDPL VEWSKPVKGH SKAQLNETGE VVNEKAKTHV 300

LDIEQRLQGI IKTRNRVTGL PLSIEGH 327

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011989	; ARM-like.
IPR016024	; ARM-type_fold.
IPR003152	; FATC.
IPR011009	; Kinase-like_dom.
IPR000403	; PI3/4_kinase_cat_dom.
IPR018936	; PI3/4_kinase_CS.
IPR003151	; PIK-rel_kinase_FAT.
IPR014009	; PIK_FAT.
IPR011990	; TPR-like_helical.
IPR012993	; UME.

Pfam

PF02259	; FAT; 1.
PF02260	; FATC; 1.
PF00454	; PI3_PI4_kinase; 1.
PF08064	; UME; 1.

SMARTs

SM00146	; PI3Kc; 1.
SM00802	; UME; 1.

Prosites

PS51189	; FAT; 1.
PS51190	; FATC; 1.
PS00916	; PI3_4_KINASE_2; 1.
PS50290	; PI3_4_KINASE_3; 1.

Prints

Created Date

20-Feb-2013