EPS-OTG-00013

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-OTG-00013

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/aDSP	118.9	1.5E-34	29	169	141

Status

Unreviewed

Ensembl Protein

ENSOGAP00000000529

UniProt Accession

H0WGR9;

Protein Name

Protein Synonyms/Alias

Gene Name

DUSP12

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000000590	ENSOGAP00000000529	ENSOGAT00000000591

Organism

Otolemur garnettii

Functional Description

Protein Length

338

Protein Sequence
(FASTA)

MLEAQGPSGS SDCRSPRASE VSYAGQMLEV LPQVYLGGAA AVSEPDHLRA AGISAVLTVD 60

SEEPSFQVGT EVEGLRRLFV PALDRPDTDL LSHLDRCVAF ISKARDEGRA VLVHCHAGVS 120

RSVAVVTAFV MKTNLVTFEE AYGHLQSVKP DAKMNEGFER QLKLYQAMGY EVDTSSAIYK 180

QYRLQVVTEK YPELQNIPQE LFAVDPATTL EGSNDKVLYK CRKCRRSLFR SSSILDHNEG 240

SGPEAFVHKR MTLPFMVSIG PRCTSYFIEP VQWMEFSLLG VMDGQLLCPK CRAKLGSFNW 300

CGEQCSCGRW ITPAFQIHKN RVDEIKALPV LGSQTRTI 338

Nucleotide Sequence
(FASTA)

ATGTTGGAGG CTCAGGGTCC CAGCGGTAGC TCCGACTGCC GGAGTCCGCG CGCGAGCGAG 60

GTCAGCTACG CCGGGCAGAT GCTGGAAGTG TTGCCGCAGG TGTACTTGGG TGGGGCCGCG 120

GCCGTCTCAG AGCCGGACCA CCTGAGGGCG GCGGGCATCT CAGCGGTGCT GACAGTGGAC 180

TCGGAGGAGC CCAGCTTCCA GGTGGGGACA GAGGTCGAGG GGCTACGGAG GCTGTTTGTG 240

CCAGCGTTAG ACAGACCCGA CACCGACCTG CTGAGCCATC TGGACCGGTG CGTGGCCTTC 300

ATCAGTAAGG CCCGCGACGA GGGGCGTGCG GTGTTAGTGC ACTGTCATGC AGGAGTCAGT 360

CGGAGTGTTG CTGTAGTGAC TGCATTTGTG ATGAAGACCA ATCTAGTTAC CTTTGAAGAG 420

GCCTATGGAC ATCTCCAGTC TGTCAAACCA GATGCTAAGA TGAATGAAGG GTTTGAGCGG 480

CAACTGAAAT TATACCAGGC AATGGGTTAT GAAGTGGATA CCTCTAGTGC AATTTATAAG 540

CAATACCGTT TACAAGTGGT TACAGAGAAG TATCCAGAGC TGCAAAATAT ACCTCAAGAA 600

CTCTTTGCTG TTGACCCAGC CACCACTTTG GAAGGATCAA ATGATAAGGT TCTCTACAAA 660

TGTAGGAAGT GCAGGAGATC CTTATTTCGA AGTTCTAGTA TTTTGGATCA TAATGAAGGA 720

AGTGGGCCTG AAGCCTTTGT CCACAAGAGA ATGACGCTAC CTTTCATGGT TAGCATAGGG 780

CCTCGGTGTA CATCTTATTT CATTGAACCT GTTCAGTGGA TGGAATTCTC TTTGTTGGGA 840

GTGATGGATG GACAGCTTCT TTGCCCAAAA TGCAGGGCCA AGTTGGGTTC CTTTAACTGG 900

TGTGGTGAAC AGTGCTCCTG TGGGAGATGG ATAACACCTG CTTTTCAAAT ACATAAGAAC 960

AGAGTGGATG AAATTAAAGC ACTGCCAGTT TTGGGGTCAC AGACAAGAAC AATATGA 1017

Domain Profile

S: 4     eilpglylgdqataldrreLsklgitvvinaslsvikvqviPeylikkgityknipvdDs  63

         e+lp++ylg++a + +  +L+++gi+ v+++  +   +qv+ e+    g + + +p+ D

Q: 29    EVLPQVYLGGAAAVSEPDHLRAAGISAVLTVDSEEPSFQVGTEVE---GLRRLFVPALDR  85

         89***************************************9985...99999*******

S: 64    dvtdllqyfdeaaefideakekggkvlvHCaaGvsRSatlvlaYLmkveglslsdAieav  123

         ++tdll+++d++++fi +a+++g++vlvHC+aGvsRS+++v+a++mk++ +++++A+  +

Q: 86    PDTDLLSHLDRCVAFISKARDEGRAVLVHCHAGVSRSVAVVTAFVMKTNLVTFEEAYGHL  145

         ************************************************************

S: 124   krkrpsiepnegfleQLlelekkl  147

         ++ +p +++negf +QL +++ ++

Q: 146   QSVKPDAKMNEGFERQLKLYQAMG  169

         ********************9886

Domain Sequence
(FASTA)

EVLPQVYLGG AAAVSEPDHL RAAGISAVLT VDSEEPSFQV GTEVEGLRRL FVPALDRPDT 60

DLLSHLDRCV AFISKARDEG RAVLVHCHAG VSRSVAVVTA FVMKTNLVTF EEAYGHLQSV 120

KPDAKMNEGF ERQLKLYQAM G 141

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0006470	; P:protein dephosphorylation

KEGG

InterPros

IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR020422	; Dual-sp_phosphatase_subgr_cat.
IPR024950	; DUSP.
IPR016278	; DUSP12.
IPR000387	; Tyr/Dual-specificity_Pase.

Pfam

PF00782

; DSPc; 1.

SMARTs

SM00195

; DSPc; 1.

Prosites

PS50056	; TYR_PHOSPHATASE_2; 1.
PS50054	; TYR_PHOSPHATASE_DUAL; 1.

Prints

Created Date

20-Feb-2013