EKS-OTG-00332

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-OTG-00332

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	320.8	6.5E-96	28	281	254

Status

Unreviewed

Ensembl Protein

ENSOGAP00000000710

UniProt Accession

H0WH77;

Protein Name

Protein Synonyms/Alias

Gene Name

TAOK1

Gene Synonyms/Alias

TAOK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000000795	ENSOGAP00000000710	ENSOGAT00000000797

Organism

Otolemur garnettii

Functional Description

Protein Length

1001

Protein Sequence
(FASTA)

MPSTNRAGSL KDPEIAELFF KEDPEKLFTD LREIGHGSFG AVYFARDVRT NEVVAIKKMS 60

YSGKQSTEKW QDIIKEVKFL QRIKHPNSIE YKGCYLREHT AWLVMEYCLG SASDLLEVHK 120

KPLQEVEIAA ITHGALQGLA YLHSHTMIHR DIKAGNILLT EPGQVKLADF GSASMASPAN 180

SFVGTPYWMA PEVILAMDEG QYDGKVDVWS LGITCIELAE RKPPLFNMNA MSALYHIAQN 240

ESPTLQSNEW SDYFRNFVDS CLQKIPQDRP TSEELLKHIF VLRERPETVL IDLIQRTKDA 300

VRELDNLQYR KMKKLLFQEA HNGPAVEAQE EEEEQDHGVG RTGTVNSVGS NQSIPSMSIS 360

ASSQSSSVNS LPDASDDKSE LDMMEGDHTV MSNSSVIHLK PEEENYREEG DSRTRASDPQ 420

SPPQVSRHKS HYRNREHFAT IRTASLVTRQ MQEHEQDSEL REQMSGYKRM RRQHQKQLMT 480

LENKLKAEMD EHRLRLDKDL ETQRNNFAAE MEKLIKKHQA AMEKEAKVMA NEEKKFQQHI 540

QAQQKKELNS FLESQKREYK LRKEQLKEEL NENQSTPKKE KQEWLSKQKE NIQHFQAEEE 600

ANLLRRQRQY LELECRRFKR RMLLGRHNLE QDLVREELNK RQTQKDLEHA MLLRQHESMQ 660

ELEFRHLNTI QKMRCELIRL QHQTELTNQL EYNKRREREL RRKHVMEVRQ QPKSLKSKEL 720

QIKKQFQDTC KIQTRQYKAL RNHLLETTPK SEHKAVLKRL KEEQTRKLAI LAEQYDHSIN 780

EMLSTQALRL DEAQEAECQV LKMQLQQELE LLNAYQSKIK MQAEAQHDRE LRELEQRVSL 840

RRALLEQKIE EEMLALQNER TERIRSLLER QAREIEAFDS ESMRLGFSNM VLSNLSPEAF 900

SHSYPGASGW SHNPTGGPGP HWGHPMGGPP QAWGHPMQGG PQPWGHPSGP MQGVPRGSSM 960

GVRNSPQALR RTASGGRTEQ GMSRSTSVTS QISNGSHMSY T 1001

Nucleotide Sequence
(FASTA)

ATGCCATCAA CTAACAGAGC GGGCAGCCTG AAGGACCCTG AAATTGCAGA GCTCTTCTTC 60

AAAGAAGATC CAGAGAAGCT CTTCACAGAT CTCAGAGAAA TTGGCCATGG AAGCTTTGGT 120

GCAGTGTATT TTGCACGAGA TGTGCGTACC AATGAAGTGG TGGCTATCAA GAAAATGTCT 180

TATAGTGGAA AGCAATCTAC TGAGAAATGG CAGGATATTA TTAAGGAAGT CAAGTTTCTA 240

CAAAGAATAA AACATCCCAA CAGTATAGAA TACAAAGGCT GTTATTTGCG AGAACACACA 300

GCATGGCTTG TAATGGAATA TTGTTTAGGA TCTGCTTCAG ATTTACTAGA AGTTCACAAA 360

AAGCCATTAC AAGAAGTGGA AATAGCTGCA ATTACACATG GTGCTCTCCA GGGATTAGCT 420

TATTTACATT CTCATACCAT GATCCACAGA GATATCAAAG CAGGAAATAT CCTTCTGACA 480

GAACCGGGCC AGGTGAAACT TGCTGACTTT GGATCTGCTT CCATGGCATC TCCTGCCAAT 540

TCCTTTGTGG GAACACCATA TTGGATGGCT CCAGAAGTAA TTTTAGCCAT GGATGAAGGA 600

CAGTATGATG GCAAAGTGGA TGTATGGTCT CTTGGAATAA CATGTATTGA ACTAGCGGAA 660

AGGAAGCCTC CTTTATTTAA TATGAATGCA ATGAGTGCCT TATATCACAT AGCCCAAAAT 720

GAATCCCCTA CACTACAGTC TAATGAATGG TCTGATTATT TTCGCAACTT TGTAGATTCT 780

TGCCTCCAGA AAATCCCTCA AGATCGTCCT ACATCAGAGG AACTTTTAAA GCACATATTT 840

GTTCTGCGAG AGCGCCCTGA AACAGTGTTA ATAGATCTCA TTCAGAGGAC AAAGGATGCA 900

GTAAGAGAGC TGGACAATCT ACAGTATCGA AAGATGAAGA AACTCCTTTT CCAGGAGGCA 960

CATAATGGAC CAGCAGTAGA AGCACAGGAA GAAGAAGAGG AACAAGATCA TGGTGTTGGC 1020

CGGACAGGAA CAGTGAATAG TGTTGGAAGT AATCAGTCTA TTCCCAGTAT GTCCATCAGT 1080

GCCAGCAGCC AAAGCAGTAG TGTTAACAGT CTTCCAGATG CCTCAGATGA CAAGAGTGAG 1140

CTAGACATGA TGGAAGGAGA CCACACAGTG ATGTCTAACA GTTCTGTCAT CCATTTAAAA 1200

CCTGAGGAAG AAAATTACAG AGAAGAGGGA GATTCTAGAA CAAGAGCATC AGACCCACAA 1260

TCCCCACCCC AAGTATCTCG TCACAAATCA CACTATCGTA ATCGAGAACA CTTTGCTACT 1320

ATACGGACAG CATCGCTGGT TACAAGGCAA ATGCAAGAAC ATGAGCAGGA CTCTGAGCTT 1380

AGAGAACAAA TGTCTGGCTA TAAGCGAATG AGGCGCCAAC ATCAGAAGCA ACTGATGACT 1440

CTGGAAAATA AGCTAAAGGC TGAGATGGAT GAACACCGCC TCAGATTGGA CAAAGATCTT 1500

GAAACTCAAC GTAACAATTT TGCTGCAGAA ATGGAGAAAC TTATCAAGAA ACATCAGGCT 1560

GCTATGGAAA AAGAGGCTAA AGTGATGGCC AATGAAGAGA AAAAATTTCA GCAACATATT 1620

CAGGCCCAAC AGAAGAAAGA ACTGAATAGC TTTTTGGAGT CACAGAAAAG AGAATATAAA 1680

CTTCGAAAAG AGCAGCTTAA AGAGGAATTG AACGAAAACC AGAGTACCCC CAAAAAAGAA 1740

AAACAAGAAT GGCTTTCAAA GCAAAAGGAG AATATACAAC ATTTCCAAGC AGAAGAAGAA 1800

GCTAACCTTC TTAGACGTCA GAGACAATAT CTAGAGCTAG AATGCCGTCG TTTTAAGAGA 1860

AGAATGTTAC TTGGACGTCA TAACTTGGAG CAGGACCTTG TCAGGGAGGA GTTAAATAAA 1920

AGGCAGACTC AGAAGGACTT GGAGCATGCC ATGCTCCTTC GACAGCATGA ATCCATGCAA 1980

GAATTGGAGT TCCGCCACCT CAACACAATT CAGAAAATGC GCTGTGAGTT GATCAGGTTG 2040

CAGCATCAAA CTGAGCTCAC TAACCAGCTG GAATATAATA AACGAAGAGA ACGAGAACTA 2100

AGAAGAAAGC ATGTCATGGA AGTTCGGCAA CAGCCTAAGA GTTTAAAGTC TAAAGAACTC 2160

CAAATAAAAA AGCAGTTTCA GGACACCTGC AAAATCCAAA CCAGACAGTA CAAAGCATTA 2220

AGGAATCACC TGCTGGAGAC TACACCAAAG AGTGAGCACA AAGCTGTTCT GAAACGGCTA 2280

AAAGAAGAAC AGACCCGGAA GTTAGCCATC TTGGCTGAAC AGTATGATCA CAGCATTAAT 2340

GAAATGCTCT CCACACAAGC CCTGCGTTTG GATGAAGCAC AGGAAGCAGA ATGCCAGGTT 2400

TTAAAGATGC AGCTGCAGCA GGAACTGGAG CTGTTGAATG CATATCAGAG CAAAATCAAG 2460

ATGCAAGCTG AGGCACAACA TGATCGAGAG CTTCGGGAGC TTGAACAGAG GGTCTCCCTC 2520

CGCAGGGCCC TCTTAGAACA AAAGATTGAA GAAGAGATGT TGGCTTTGCA AAATGAACGC 2580

ACAGAACGAA TACGAAGCCT ACTGGAGCGT CAAGCGAGAG AAATTGAAGC TTTTGACTCT 2640

GAAAGCATGA GACTAGGTTT TAGTAACATG GTCCTTTCTA ATCTCTCCCC TGAGGCATTC 2700

AGCCACAGCT ACCCAGGAGC TTCTGGTTGG TCTCACAATC CTACTGGGGG TCCAGGACCT 2760

CACTGGGGTC ATCCCATGGG TGGCCCACCA CAAGCTTGGG GCCATCCAAT GCAAGGTGGA 2820

CCCCAGCCAT GGGGTCACCC CTCGGGGCCA ATGCAAGGGG TACCTCGAGG TAGCAGTATG 2880

GGAGTCCGCA ATAGCCCCCA GGCACTAAGG CGGACAGCTT CTGGGGGACG GACAGAGCAG 2940

GGCATGAGCA GAAGCACGAG TGTCACATCA CAAATATCCA ATGGGTCACA CATGTCTTAT 3000

ACATAA 3006

Domain Profile

S: 1     yelleeigkGalgkvylarekktgelvaikkinlekq...ekleelqkeisvlkklkhpn  57

         ++ l+eig+G++g+vy ar+++t+e+vaikk++++ +   ek+++++ke+++l+++khpn

Q: 28    FTDLREIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKqstEKWQDIIKEVKFLQRIKHPN  87

         67899*****************************988889********************

S: 58    iveylesflkeeelwlvmeylagGslsdlvkeelkselkEeqiayilrevlkaLeylHsk  117

          +ey +++l+e++ wlvmey+  Gs+sdl++ ++k++l+E +ia+i++++l++L+ylHs+

Q: 88    SIEYKGCYLREHTAWLVMEYCL-GSASDLLE-VHKKPLQEVEIAAITHGALQGLAYLHSH  145

         *********************7.********.****************************

S: 118   kviHrdikakniLlteegeVkLsdfgvaaqlektrkkrktvvgtpywmAPEviaqe.ekg  176

          +iHrdika+niLlte g+VkL+dfg+a+  +      +++vgtpywmAPEvi ++ e +

Q: 146   TMIHRDIKAGNILLTEPGQVKLADFGSASMASP----ANSFVGTPYWMAPEVILAMdEGQ  201

         **************************9998888....69**************9887999

S: 177   YdekaDiwslGItaielaegepPfkdleplkallkilkneppklkskkkfskefkefvek  236

         Yd k+D+wslGIt+ielae++pP++++++++al++i++ne+p+l+s+ ++s+ f++fv++

Q: 202   YDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPTLQSN-EWSDYFRNFVDS  260

         ********************************************888.************

S: 237   clqknpekRpsasellkhkFl  257

         clqk p++Rp+++ellkh F+

Q: 261   CLQKIPQDRPTSEELLKHIFV  281

         ******************997

Domain Sequence
(FASTA)

FTDLREIGHG SFGAVYFARD VRTNEVVAIK KMSYSGKQST EKWQDIIKEV KFLQRIKHPN 60

SIEYKGCYLR EHTAWLVMEY CLGSASDLLE VHKKPLQEVE IAAITHGALQ GLAYLHSHTM 120

IHRDIKAGNI LLTEPGQVKL ADFGSASMAS PANSFVGTPY WMAPEVILAM DEGQYDGKVD 180

VWSLGITCIE LAERKPPLFN MNAMSALYHI AQNESPTLQS NEWSDYFRNF VDSCLQKIPQ 240

DRPTSEELLK HIFV 254

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013