EPS-OTG-00022

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-OTG-00022

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	273.7	1.8E-81	61	373	313

Status

Unreviewed

Ensembl Protein

ENSOGAP00000000982

UniProt Accession

H0WHW0;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1D

Gene Synonyms/Alias

PPM1D;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000001105	ENSOGAP00000000982	ENSOGAT00000001106

Organism

Otolemur garnettii

Functional Description

Protein Length

605

Protein Sequence
(FASTA)

MAGLYSLGVS VFSDQGGRKY MEDVTQIVVE PEQTAEEKPS PRRSLSQPSP TRPSPSALPG 60

GAVSGNGPAV AARDVRDPPP DAGASPAPGR CCRRRSSVAF FAVCDGHGGR EAAQFAREHL 120

WGFIKKQKGF TSSEPAKVCA AIRKGFLACH LAMWKKLAEW PKTMTGLPST SGTTASVVII 180

RGMKMYVAHV GDSGVVLGIQ DDPKDDFVRA VEVTQDHKPE LPKERERIEG LGGSVMNKSG 240

VNRVVWKRPR LTHNGPVRRS TVIDQIPFLA VARALGDLWS YDFFSGEFVV SPEPDTSVHT 300

LDPQKHKYII LGSDGLWNMI PPQDAVSMCQ DQEEKKSLMG EHGQSCAKML VNRALGRWRQ 360

RMLRADNTSA IVICISPEVD SQGNFTNEDE FYLNLTESPS YNSQETCVMT PSPCSTPPVK 420

LLEEDPWPRL NSKDHIPALV RSNAFSENFL EVPAEISRGS VQAVVLPSKD AQPLEENCAK 480

ALTLRIHDSL NNSLSVGLVP TNSTNTIMDQ KNLKMSTPGQ MKAQEIERTP PANFKRTLEE 540

SNSGPLMKKH RRNGLNRSNG AQPANLPTTS QRKNSVKLTM RRRLRGQKKI GNPLLHQHRK 600

TVCVC 605

Nucleotide Sequence
(FASTA)

ATGGCGGGGC TGTACTCGCT GGGAGTGAGC GTTTTCTCCG ACCAGGGCGG GAGGAAGTAC 60

ATGGAGGACG TTACCCAAAT CGTTGTAGAG CCCGAGCAGA CGGCCGAAGA AAAGCCGTCG 120

CCGCGGCGGT CGCTGTCTCA GCCGTCGCCG ACGCGGCCGT CGCCGTCAGC TCTTCCTGGC 180

GGCGCAGTCT CGGGGAACGG CCCAGCAGTG GCAGCCCGAG ACGTTCGCGA CCCTCCCCCG 240

GACGCCGGGG CCTCGCCGGC TCCCGGCCGC TGCTGCCGCC GCCGTTCCTC AGTGGCCTTC 300

TTCGCCGTGT GTGACGGGCA CGGCGGGCGG GAGGCGGCAC AGTTTGCCCG GGAGCATTTG 360

TGGGGTTTCA TCAAGAAGCA AAAGGGTTTC ACCTCGTCCG AGCCGGCGAA GGTTTGCGCT 420

GCCATCCGCA AAGGCTTCCT CGCTTGTCAC CTCGCTATGT GGAAGAAACT GGCGGAATGG 480

CCCAAGACTA TGACAGGTCT TCCCAGCACA TCAGGGACAA CTGCCAGTGT GGTCATCATA 540

CGGGGCATGA AGATGTATGT AGCTCACGTA GGTGACTCAG GAGTGGTTCT TGGAATTCAG 600

GATGACCCAA AGGATGATTT TGTCAGAGCT GTGGAGGTGA CACAGGACCA TAAGCCAGAG 660

CTACCCAAGG AAAGAGAACG AATTGAAGGA CTTGGCGGGA GTGTGATGAA CAAGTCTGGA 720

GTGAATCGTG TAGTTTGGAA GCGACCTCGA CTCACTCACA ATGGGCCTGT TAGAAGGAGC 780

ACAGTTATTG ACCAGATACC TTTTCTGGCA GTAGCAAGAG CACTTGGTGA TTTGTGGAGC 840

TACGATTTCT TCAGTGGTGA GTTTGTGGTG TCTCCTGAAC CAGACACGAG TGTTCACACT 900

CTTGACCCCC AGAAGCACAA GTATATTATC TTAGGGAGTG ATGGGCTTTG GAATATGATT 960

CCACCTCAAG ATGCCGTCTC AATGTGTCAG GACCAAGAGG AGAAAAAATC CCTGATGGGT 1020

GAGCATGGAC AATCTTGTGC CAAAATGCTT GTGAATCGAG CACTAGGCCG CTGGAGGCAG 1080

CGTATGCTCC GAGCAGATAA CACAAGTGCC ATAGTAATCT GCATCTCTCC AGAAGTGGAC 1140

AGTCAGGGAA ACTTTACCAA TGAAGATGAA TTCTATCTGA ACCTGACTGA AAGCCCTTCC 1200

TACAATAGTC AAGAAACCTG TGTAATGACT CCTTCTCCAT GTTCTACACC ACCAGTCAAG 1260

TTACTTGAGG AGGATCCATG GCCGAGGCTG AACTCTAAAG ACCATATACC TGCTCTAGTT 1320

CGTAGTAATG CTTTCTCAGA AAATTTTTTA GAGGTACCAG CTGAGATATC TCGAGGGAGT 1380

GTCCAAGCTG TAGTCCTACC CTCAAAAGAT GCACAGCCTC TTGAAGAAAA TTGTGCTAAA 1440

GCCCTAACTT TAAGGATACA TGATTCTTTG AATAATAGCC TGTCTGTTGG CCTTGTTCCT 1500

ACCAATTCAA CAAACACCAT CATGGACCAA AAAAATTTAA AGATGTCAAC TCCTGGTCAA 1560

ATGAAAGCCC AAGAAATTGA AAGAACCCCT CCAGCAAACT TTAAAAGGAC ATTAGAAGAA 1620

TCCAACTCTG GCCCCCTTAT GAAAAAGCAT AGACGAAATG GTTTAAATCG AAGTAATGGT 1680

GCTCAGCCTG CAAACCTCCC CACAACTTCT CAGCGAAAGA ACTCTGTTAA ACTTACCATG 1740

CGACGCAGAC TTAGAGGCCA GAAGAAAATT GGAAATCCTT TACTACATCA GCACAGGAAA 1800

ACTGTTTGTG TTTGCTGA 1818

Domain Profile

S: 4     gvvsvngrrnemedavtsspnflkspekkdr......laffgvyDGhggsevakfcsekl  57

         g vs+ng+    +d +++ p++++sp+  ++      +aff+v+DGhgg+e+a+f++e+l

Q: 61    GAVSGNGPAVAARDVRDPPPDAGASPAPGRCcrrrssVAFFAVCDGHGGREAAQFAREHL  120

         67999***********************999*****************************

S: 58    heilaeelesseseerkvkkalakaFlstdeel.....kvleeksldidksGstavvali  112

         + ++++++ +++se +kv++a++k+Fl+++ ++     +++++++  +++sG+ta+v++i

Q: 121   WGFIKKQKGFTSSEPAKVCAAIRKGFLACHLAMwkklaEWPKTMTGLPSTSGTTASVVII  180

         ************************************************************

S: 113   kdsklyvanvGdSravLcrngk.......avelssdHkpsredEleRieeaggsvilkdg  165

         +++k+yva+vGdS++vL+ +++       ave+++dHkp+ ++E+eRie  ggsv++k+g

Q: 181   RGMKMYVAHVGDSGVVLGIQDDpkddfvrAVEVTQDHKPELPKERERIEGLGGSVMNKSG  240

         *******************77656999999******************************

S: 166   a.Rv.....................lGvLavsRalGdlylk......pyvtpePevtshr  197

         + Rv                     +++Lav+RalGdl+++      ++v+peP++++h+

Q: 241   VnRVvwkrprlthngpvrrstvidqIPFLAVARALGDLWSYdffsgeFVVSPEPDTSVHT  300

         ************************************************************

S: 198   ltsede.fliLasDGlwdvvsneeavslvrdvle....kkeaeqeaakkLvklalargsk  252

         l+++++ ++iL+sDGlw+++++++avs+++d++e    ++e+ q++ak+Lv++al r+++

Q: 301   LDPQKHkYIILGSDGLWNMIPPQDAVSMCQDQEEkkslMGEHGQSCAKMLVNRALGRWRQ  360

         ************************************************************

S: 253   .....dnvsaivv  260

              dn+saiv+

Q: 361   rmlraDNTSAIVI  373

         ***********97

Domain Sequence
(FASTA)

GAVSGNGPAV AARDVRDPPP DAGASPAPGR CCRRRSSVAF FAVCDGHGGR EAAQFAREHL 60

WGFIKKQKGF TSSEPAKVCA AIRKGFLACH LAMWKKLAEW PKTMTGLPST SGTTASVVII 120

RGMKMYVAHV GDSGVVLGIQ DDPKDDFVRA VEVTQDHKPE LPKERERIEG LGGSVMNKSG 180

VNRVVWKRPR LTHNGPVRRS TVIDQIPFLA VARALGDLWS YDFFSGEFVV SPEPDTSVHT 240

LDPQKHKYII LGSDGLWNMI PPQDAVSMCQ DQEEKKSLMG EHGQSCAKML VNRALGRWRQ 300

RMLRADNTSA IVI 313

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>