EKS-OTG-00237

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-OTG-00237

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE7	268.4	6.4E-80	168	357	190

Status

Unreviewed

Ensembl Protein

ENSOGAP00000002220

UniProt Accession

H0WKU1;

Protein Name

Protein Synonyms/Alias

Gene Name

MAP2K5

Gene Synonyms/Alias

MAP2K5;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000002480	ENSOGAP00000002220	ENSOGAT00000002485

Organism

Otolemur garnettii

Functional Description

Protein Length

358

Protein Sequence
(FASTA)

MLWLTLGPFH AMENQVLVIR IKIPNSGAVD WTVHSGPQLL FRDVLDVIGQ VLPEATTTAF 60

EYEDEDGDRI TVRSDEEMKA MLSYYYSTVM EQQVNGQLIE PLQIFPRACK PPGERNIHGL 120

KVNTRAGPSQ HSSPAVSDSL PSNSLKKSSA ELKKILANGQ MNEQDIRYRD TLGHGNGGTV 180

YKAHHVPSGK ILAVKVILLD ITLELQKQIM SELEILYKCD SSYIIGFYGA FFVENRISIC 240

TEFMDGGSLD VYRKIPEHVL GRIAVAVVKG LTYLWSLKIL HRDVKPSNML VNTRGQVKLC 300

DFGVSTQLVN SIAKTYVGTN AYMAPERISG EQYGIHSDVW SLGISFMEIL WGQFTVPQ 358

Nucleotide Sequence
(FASTA)

ATGCTCTGGC TGACCCTTGG CCCCTTCCAT GCCATGGAGA ACCAGGTGCT GGTGATTCGC 60

ATCAAGATTC CAAATAGTGG GGCAGTGGAC TGGACAGTGC ACTCCGGGCC GCAGTTACTC 120

TTCAGGGATG TGCTGGATGT GATAGGCCAG GTTCTGCCCG AAGCAACAAC TACAGCATTT 180

GAATATGAAG ATGAAGATGG TGATCGAATT ACAGTGAGAA GTGATGAAGA AATGAAGGCA 240

ATGCTGTCAT ATTATTATTC CACAGTAATG GAGCAGCAAG TAAATGGACA GTTAATAGAG 300

CCACTGCAGA TATTTCCAAG AGCCTGCAAG CCTCCTGGGG AACGGAACAT ACATGGCCTG 360

AAGGTGAATA CCCGGGCCGG ACCCTCTCAA CACAGCAGCC CAGCAGTCTC AGATTCACTT 420

CCAAGCAATA GTCTAAAGAA ATCTTCTGCT GAATTGAAAA AAATATTAGC CAATGGCCAG 480

ATGAATGAAC AAGACATACG GTATCGAGAC ACCCTTGGTC ATGGCAACGG AGGCACAGTC 540

TACAAAGCCC ATCATGTCCC GAGTGGGAAA ATATTAGCTG TAAAGGTCAT ACTATTAGAT 600

ATTACACTGG AACTTCAGAA GCAAATCATG TCTGAATTGG AAATTCTTTA CAAGTGTGAT 660

TCATCATATA TCATAGGATT TTATGGGGCG TTTTTTGTAG AAAACAGAAT TTCAATATGT 720

ACAGAATTCA TGGATGGGGG ATCTTTGGAT GTATATAGGA AAATTCCAGA GCACGTCCTT 780

GGAAGAATTG CAGTAGCGGT TGTTAAAGGC CTTACTTATT TGTGGAGTTT AAAGATTTTA 840

CATAGAGATG TGAAACCCTC CAATATGCTA GTCAACACAA GAGGACAAGT CAAGCTGTGT 900

GATTTTGGAG TTAGCACTCA GCTGGTGAAT TCTATAGCCA AGACGTATGT TGGAACAAAT 960

GCTTATATGG CGCCTGAAAG AATTTCAGGG GAGCAATATG GAATCCATTC TGATGTCTGG 1020

AGCTTAGGAA TCTCTTTCAT GGAGATTTTG TGGGGCCAGT TCACTGTCCC TCAG 1074

Domain Profile

S: 3     kleelGaGnggvVekvlhkksgkilavKtirleikkeeqkqilrelevlkkssnspyivk  62

           ++lG+Gngg+V+k++h +sgkilavK i l+i+ e qkqi++ele+l k+ +s+yi++

Q: 168   YRDTLGHGNGGTVYKAHHVPSGKILAVKVILLDITLELQKQIMSELEILYKC-DSSYIIG  226

         5689************************************************.*******

S: 63    fyGafvsegdvsicmelmdgtsldkvlkkvlekkkripekvlgkiavavvkaleylkekl  122

         fyGaf+ e+++sic+e+mdg+sld v++k       ipe+vlg+iavavvk+l+yl+ +l

Q: 227   FYGAFFVENRISICTEFMDGGSLD-VYRK-------IPEHVLGRIAVAVVKGLTYLW-SL  277

         ************************.6876.......9********************.78

S: 123   kiiHRDvKPsNiLvnskGevKlCDFGvsgqlvdsiAksavGtksYmaPEriegkkkYsvk  182

         ki+HRDvKPsN+Lvn++G+vKlCDFGvs+qlv+siAk++vGt++YmaPEri+g ++Y ++

Q: 278   KILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISG-EQYGIH  336

         *****************************************************.******

S: 183   sdvWslGltlvelatgrypye  203

         sdvWslG++++e+  g++ ++

Q: 337   SDVWSLGISFMEILWGQFTVP  357

         ******************986

Domain Sequence
(FASTA)

YRDTLGHGNG GTVYKAHHVP SGKILAVKVI LLDITLELQK QIMSELEILY KCDSSYIIGF 60

YGAFFVENRI SICTEFMDGG SLDVYRKIPE HVLGRIAVAV VKGLTYLWSL KILHRDVKPS 120

NMLVNTRGQV KLCDFGVSTQ LVNSIAKTYV GTNAYMAPER ISGEQYGIHS DVWSLGISFM 180

EILWGQFTVP 190

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>