EPS-OTG-00030

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-OTG-00030

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	188.9	1.3E-55	780	1026	247

Status

Unreviewed

Ensembl Protein

ENSOGAP00000002557

UniProt Accession

H0WLL5;

Protein Name

Protein Synonyms/Alias

Gene Name

PHLPP2

Gene Synonyms/Alias

PHLPP2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000002853	ENSOGAP00000002557	ENSOGAT00000002857

Organism

Otolemur garnettii

Functional Description

Protein Length

1318

Protein Sequence
(FASTA)

MKRNGSRNCL NRRSRFGSRE RDWLREDVKR GCVYLYGADT TTATPTTTSS SSSSSDLHLV 60

LCTVETPASE ICAGEGRESL YLQLHGDLVR RLEPIERPLQ IVYDYLSKLG FDDPVRIQEE 120

ATNPDLGCMI RFYGEKPCQM DHLDRILLSG IYNVRKGKTQ LHKWAERLVV LCGTCLIVSS 180

VKDCQTGKMH ILPLVGGKVE EVKRRQYSLA FSSAGAQAQT YHVSFETLAE YQRWQRQASK 240

VVSQRISTVD LSCYSLEEVP EHLFYSQDIT YLNLRHNFMQ LERPGGLDTL YKFSQLKGLN 300

LSHNKLGSFP VLLCEISTLT ELNLSCNGFH DLPSQIGNLL NLQTLCLDGN FLTTLPEELG 360

NLQQLSSLGI SFNNFSQIPE VYEKLTMLDK VVMAGNCLEV LSLGVLNRMS HVKHVDLRLN 420

HLKTVVIENL EGNKYVTHVD LRDNQLTDLD LSSLCGLEQL HCERNQLREL TLSGFSLRTL 480

YASSNRLTAV NVYPVPSLLT SLELSRNLLE CVPDWACDAK KIEVLDMSYN LLTEVPMRIL 540

SSLSLRKLMV GHNRVQTLPA LVEHIPLEVL DIQHNILTRL PDTLFSKALN LRYLNASANS 600

LESLPSACAG EESLSMLQLL YLTSNLLTDQ CIPVLVGHPH LRILHLANNQ LQTFPASKLS 660

KLEQLEELNL SGNKLKTIPT TIASCKRLHT LVAHSNNISI FPEILQLPQI QFVDLSCNDL 720

TEILIPEALP VTLQDLDLTG NTNLVLEHKT LDIFSHITTL KIDQKPLPTT DSTVTSTFWS 780

HGLAEMAGQR NKLCVSALAM DNFAEGVGAV YGMFDGDRNE ELPRLLQCTM ADVLLEEVQH 840

STNDTVFMSN TFLVSHRKLG MAGQKLGSSA LLCYIRPDTA DPTSSFSLTV ANVGTCQAVL 900

CRSGKPLPLS KIFSLEQDPE EAQRVKEQKA IITEDNKVNG VTCCTRLLGC TYLYPWVLPK 960

PHISSTPLTI QDELLILGNK ALWEHLSYTE AVNAVRHVQD PLAAAKKLCT LAQSYGCQDN 1020

VGAMVVYLNI GEEGCTCEMN GLTLPGPVGY ASTTTVKDMP KPTTPSSSSG IASEFSSEMS 1080

TSEVSSEVGS TASDEHNAVG LDATLLPRPE RRCSLHPAPS SGVFQRQPSC ATFSSNQSDN 1140

GLDSDDDQPV EGVISNGSRV EVEVDIHCCR GRDPENTTAL AGNPPVPCPE EHARGLGFGI 1200

RRQNSVNSGI LLPMSKDRME LQKSPSTSCL YGKKLSNGSI VPLEDSLNLI EVATEAPKRK 1260

TGYFAAPTQL EPEDQFVVPR DLEEEVKEQM KQHQESRLEP EPREEDRTEP PEEFDTAL 1318

Nucleotide Sequence
(FASTA)

ATGAAACGCA ATGGAAGCAG AAATTGTTTG AATAGGAGGA GTAGGTTTGG TTCTCGAGAA 60

AGAGACTGGC TGCGAGAAGA TGTGAAGAGA GGCTGTGTTT ACCTTTATGG AGCAGACACT 120

ACCACTGCCA CTCCAACCAC CACCTCCTCT TCTTCCTCCT CCTCTGACTT GCATCTTGTC 180

CTTTGCACAG TAGAGACACC AGCATCAGAA ATATGTGCTG GAGAAGGCAG AGAAAGTCTT 240

TATTTACAGC TCCACGGAGA CCTGGTCAGG AGACTGGAAC CTATTGAACG ACCTCTTCAG 300

ATTGTGTATG ATTACTTGTC CAAACTGGGA TTTGATGATC CTGTGCGTAT ACAGGAGGAG 360

GCTACAAATC CTGACCTTGG CTGTATGATT CGATTTTATG GTGAGAAACC ATGTCAGATG 420

GATCATCTGG ATCGAATCTT ACTGTCTGGC ATCTATAACG TACGCAAGGG AAAGACTCAA 480

CTGCACAAGT GGGCGGAACG CCTGGTGGTT CTCTGTGGTA CCTGCCTTAT TGTTTCCTCG 540

GTGAAGGATT GTCAAACTGG AAAGATGCAC ATTTTGCCTC TGGTTGGGGG AAAGGTAGAA 600

GAAGTGAAGC GACGGCAGTA CTCCCTGGCA TTCAGCTCCG CTGGAGCCCA AGCTCAGACC 660

TATCACGTCA GCTTTGAGAC TTTGGCAGAG TACCAGAGAT GGCAACGGCA AGCGTCCAAG 720

GTGGTGTCCC AGCGCATCAG TACTGTGGAT CTCTCGTGTT ACAGCCTGGA GGAGGTTCCT 780

GAGCATCTCT TCTACAGTCA AGATATCACC TACCTCAACT TGCGACACAA CTTCATGCAG 840

CTAGAAAGAC CAGGGGGCCT TGACACGCTC TACAAATTTT CTCAGCTGAA GGGCCTAAAC 900

TTGTCCCACA ATAAACTCGG GTCGTTTCCT GTGTTGTTGT GTGAGATCTC CACCCTGACT 960

GAGCTCAACC TTTCCTGCAA TGGATTTCAT GACCTACCAA GTCAGATTGG CAATTTGCTA 1020

AATCTTCAAA CTCTCTGTCT TGATGGCAAT TTTCTGACTA CTTTACCTGA AGAACTGGGA 1080

AATCTGCAAC AGCTTTCCTC CCTGGGAATT TCGTTCAACA ACTTTAGTCA AATCCCTGAG 1140

GTTTATGAGA AACTCACTAT GTTAGATAAA GTGGTTATGG CAGGAAATTG CCTGGAAGTG 1200

CTCAGCCTGG GGGTGCTGAA CAGAATGAGC CATGTCAAGC ATGTGGACTT GAGGTTGAAC 1260

CATTTGAAAA CTGTGGTTAT CGAAAATCTG GAGGGAAATA AATACGTCAC TCACGTGGAT 1320

CTCCGAGACA ATCAGCTGAC TGACTTAGAT CTCAGCTCCT TGTGTGGCTT GGAGCAGCTG 1380

CACTGTGAGC GGAACCAGCT GAGGGAGTTG ACCCTCAGTG GCTTCTCCCT TCGAACTCTC 1440

TACGCCAGTT CCAACAGGCT GACAGCAGTG AATGTCTACC CAGTCCCCAG TCTGCTCACT 1500

TCTCTAGAAC TCTCCCGAAA CCTGCTAGAA TGTGTTCCTG ACTGGGCCTG CGATGCAAAG 1560

AAGATAGAAG TATTAGATAT GAGCTATAAT CTTCTCACTG AGGTTCCTAT GAGAATTCTA 1620

AGTAGCTTGA GCCTTAGGAA ATTGATGGTG GGACACAACC GTGTGCAGAC CCTGCCGGCG 1680

CTGGTGGAGC ACATCCCCCT GGAGGTGCTG GATATTCAGC ATAACATACT CACCAGGCTG 1740

CCAGACACTC TGTTCTCCAA GGCCTTAAAT CTCAGATACT TGAATGCGTC TGCAAATAGT 1800

TTGGAGTCTT TACCATCCGC CTGCGCTGGG GAGGAGAGTC TGAGCATGCT GCAGCTGCTT 1860

TACTTGACCA GCAATCTCCT GACAGATCAG TGCATTCCTG TCCTGGTAGG ACACCCTCAC 1920

CTGCGAATCT TGCACCTTGC AAACAACCAG CTACAGACCT TTCCTGCAAG CAAACTAAGT 1980

AAATTGGAGC AATTGGAGGA ACTAAACCTA AGTGGCAATA AGCTTAAAAC CATCCCCACA 2040

ACCATAGCCA GCTGCAAAAG GCTGCACACC CTTGTTGCAC ACTCCAACAA TATCAGCATT 2100

TTCCCAGAGA TCCTGCAGTT GCCTCAGATC CAGTTTGTAG ACCTAAGTTG CAATGACTTG 2160

ACAGAAATCC TGATCCCAGA GGCATTGCCT GTTACATTAC AAGACCTTGA CCTGACTGGA 2220

AATACAAATC TGGTTCTGGA GCACAAGACT CTGGACATAT TTAGCCATAT CACAACCCTG 2280

AAAATTGATC AGAAACCTTT GCCAACCACA GATTCTACAG TTACATCAAC CTTCTGGAGC 2340

CATGGACTGG CTGAAATGGC AGGGCAGAGA AATAAGCTGT GTGTATCTGC CCTCGCCATG 2400

GATAACTTTG CCGAGGGAGT GGGAGCTGTG TACGGCATGT TTGATGGGGA CAGAAACGAG 2460

GAGCTCCCTC GCCTGCTCCA GTGTACGATG GCTGACGTGC TGTTGGAAGA GGTGCAGCAC 2520

TCAACAAATG ACACTGTTTT CATGTCTAAC ACCTTCTTGG TATCTCACAG GAAACTGGGA 2580

ATGGCTGGCC AGAAGCTGGG CTCCTCTGCC CTCCTGTGCT ACATCCGCCC CGACACTGCC 2640

GACCCCACAA GTAGTTTTAG CTTGACTGTG GCCAACGTTG GCACATGCCA AGCAGTCCTG 2700

TGCCGAAGTG GGAAGCCACT GCCACTCTCT AAAATCTTCA GCCTGGAGCA GGACCCAGAG 2760

GAGGCACAAA GGGTAAAAGA ACAAAAAGCC ATCATCACTG AGGACAACAA AGTGAATGGT 2820

GTGACCTGTT GTACCCGGCT GCTGGGCTGT ACATACCTCT ACCCCTGGGT CCTCCCCAAG 2880

CCTCACATTT CTTCCACTCC ACTTACCATT CAAGATGAGT TGCTGATTCT AGGAAACAAA 2940

GCACTATGGG AACACTTGTC CTACACAGAA GCTGTCAATG CAGTGCGTCA TGTACAAGAC 3000

CCGTTAGCAG CTGCCAAGAA GCTGTGCACA TTAGCACAGA GTTATGGTTG TCAGGACAAC 3060

GTAGGGGCCA TGGTGGTCTA TCTGAATATT GGCGAGGAAG GCTGCACATG TGAAATGAAT 3120

GGGCTCACCC TGCCTGGGCC TGTGGGATAT GCCTCTACCA CCACAGTCAA GGACATGCCA 3180

AAGCCAACCA CTCCCTCCTC TAGCAGTGGG ATCGCCTCTG AGTTCAGCAG TGAGATGTCC 3240

ACCTCGGAGG TGAGCAGCGA GGTGGGGTCC ACCGCTTCTG ATGAGCATAA CGCCGTGGGC 3300

CTGGATGCCA CCTTGCTCCC ACGGCCAGAA AGGCGCTGCA GCCTCCATCC AGCACCCAGC 3360

TCTGGGGTTT TTCAGCGCCA GCCTTCTTGT GCCACCTTCT CCAGTAATCA GTCTGACAAT 3420

GGCTTGGACA GTGATGATGA CCAGCCCGTT GAAGGGGTCA TAAGCAATGG CAGCAGGGTA 3480

GAAGTGGAGG TAGACATCCA CTGCTGCAGA GGGAGAGACC CGGAGAACAC CACTGCTCTC 3540

GCAGGGAATC CTCCTGTCCC GTGTCCCGAG GAACATGCCA GAGGGCTGGG CTTTGGGATC 3600

CGAAGACAGA ACAGTGTGAA TAGTGGTATC CTCCTGCCGA TGAGTAAGGA CAGGATGGAG 3660

TTACAGAAGT CTCCTTCCAC CTCCTGTCTC TATGGAAAGA AACTCTCCAA TGGCTCTATT 3720

GTGCCTCTGG AAGATAGCCT GAACCTCATC GAAGTGGCCA CAGAAGCACC CAAGAGGAAA 3780

ACTGGCTACT TTGCTGCCCC TACTCAGCTG GAACCAGAGG ATCAGTTTGT TGTACCCCGG 3840

GACCTGGAAG AAGAAGTAAA GGAGCAAATG AAACAGCACC AGGAAAGCAG GCTTGAGCCT 3900

GAGCCCAGGG AAGAGGATCG GACCGAGCCC CCAGAGGAGT TTGACACAGC GCTGTGA 3957

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g++++ g+rn+++ ++ +++nf++  +     a++g++DG++++e  + +++++ ++l

Q: 780   SHGLAEMAGQRNKLCVSALAMDNFAEGVG-----AVYGMFDGDRNEELPRLLQCTMADVL  834

         6899*********************9877.....59************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

          ee++    ++++ + ++ ++Fl  +++l       ++ +k Gs+a++++i+++

Q: 835   LEEVQ----HSTNDTVFMSNTFLVSHRKL------GMAGQKLGSSALLCYIRPDtadpts  884

         ***99....88888889************......89***************999999**

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsre.dEleRieeaggsvilkdgaRvlGvL  172

           +l+vanvG ++avLcr+gk+++ls+ ++ +++ +E +R++e+++ +++++  +v+Gv+

Q: 885   sfSLTVANVGTCQAVLCRSGKPLPLSKIFSLEQDpEEAQRVKEQKAIITEDN--KVNGVT  942

         ******************************98866**********9999998..******

S: 173   avsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekk  232

         +++R lG++yl+p+v p+P+++s++lt +de liL+ + lw+++s  eav++vr+v +

Q: 943   CCTRLLGCTYLYPWVLPKPHISSTPLTIQDELLILGNKALWEHLSYTEAVNAVRHVQD--  1000

         **********************************************************..

S: 233   eaeqeaakkLvklalargskdnvsaivv  260

           + +aakkL++la+++g++dnv a+vv

Q: 1001  --PLAAAKKLCTLAQSYGCQDNVGAMVV  1026

         ..************************97

Domain Sequence
(FASTA)

SHGLAEMAGQ RNKLCVSALA MDNFAEGVGA VYGMFDGDRN EELPRLLQCT MADVLLEEVQ 60

HSTNDTVFMS NTFLVSHRKL GMAGQKLGSS ALLCYIRPDT ADPTSSFSLT VANVGTCQAV 120

LCRSGKPLPL SKIFSLEQDP EEAQRVKEQK AIITEDNKVN GVTCCTRLLG CTYLYPWVLP 180

KPHISSTPLT IQDELLILGN KALWEHLSYT EAVNAVRHVQ DPLAAAKKLC TLAQSYGCQD 240

NVGAMVV 247

Keyword

Complete proteome; Leucine-rich repeat; Reference proteome; Repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>