EKS-OTG-00233

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-OTG-00233

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE7	381.8	1.7E-114	53	314	262

Status

Unreviewed

Ensembl Protein

ENSOGAP00000003993

UniProt Accession

H0WPZ2;

Protein Name

Protein Synonyms/Alias

Gene Name

MAP2K3

Gene Synonyms/Alias

MAP2K3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000004471	ENSOGAP00000003993	ENSOGAT00000004475

Organism

Otolemur garnettii

Functional Description

Protein Length

336

Protein Sequence
(FASTA)

MPQPKGKSKR KKDLRISCVS KSPVPNPTPP RNLDSRTFIT IGDRNFEVEA DDLVTISELG 60

RGAYGVVEKV RHAQSGTIMA VKRIRATVNS QEQKRLLMDL DINMRTVDCF YTVTFYGALF 120

REGDVWICME LMDTSLDKFY RKVLDKNMTI PEDILGEIAV SIVRALEHLH SKLSVIHRDV 180

KPSNVLINKE GHVKMCDFGI SGYLVDSVAK TMDAGCKPYM APERINPELN QKGYNVKSDV 240

WSLGITMIEM AILRFPYESW GTPFQQLKQV VEEPSPQLPA EHFSPEFVDF TAQCLRKNPA 300

ERMSYLELME HPFFTLHKTK KTDIAAFVKE ILGEDS 336

Nucleotide Sequence
(FASTA)

ATGCCCCAGC CCAAAGGAAA ATCCAAGAGG AAGAAGGACT TACGAATATC TTGTGTGTCC 60

AAGTCACCTG TGCCCAACCC CACACCCCCC CGGAACCTGG ATTCCCGGAC CTTCATCACC 120

ATCGGAGACA GAAACTTTGA GGTGGAGGCT GATGACCTGG TGACCATCTC GGAACTGGGC 180

CGGGGAGCCT ATGGGGTGGT GGAGAAGGTG CGGCATGCCC AAAGTGGCAC CATCATGGCC 240

GTGAAGCGGA TCCGGGCCAC CGTGAACTCA CAGGAGCAGA AGCGGCTGCT CATGGACCTG 300

GACATCAACA TGCGTACAGT TGACTGCTTC TACACCGTCA CCTTCTACGG GGCCCTCTTC 360

CGAGAGGGAG ACGTGTGGAT CTGCATGGAG CTCATGGACA CATCCCTGGA CAAATTCTAC 420

CGGAAGGTGC TGGATAAAAA CATGACAATT CCAGAGGACA TTCTGGGCGA GATTGCTGTG 480

TCTATCGTGC GGGCACTGGA GCACCTGCAT AGCAAGCTGT CGGTGATTCA CAGAGATGTG 540

AAGCCCTCCA ACGTCCTCAT CAACAAGGAG GGCCATGTGA AGATGTGTGA CTTCGGCATC 600

AGTGGCTATT TGGTGGACTC TGTGGCTAAG ACGATGGATG CTGGCTGCAA GCCCTACATG 660

GCTCCTGAGA GAATCAATCC GGAGCTGAAC CAGAAAGGCT ACAATGTCAA GTCTGATGTC 720

TGGAGTCTTG GCATCACCAT GATTGAGATG GCCATTCTAC GGTTCCCTTA TGAGTCCTGG 780

GGGACCCCAT TCCAGCAGCT GAAGCAGGTG GTGGAGGAGC CATCTCCCCA GCTTCCAGCT 840

GAGCATTTCT CCCCTGAGTT TGTAGACTTC ACTGCACAGT GCCTGAGGAA GAACCCTGCC 900

GAACGCATGA GCTACCTGGA ACTGATGGAG CACCCCTTCT TTACTTTGCA TAAAACCAAG 960

AAGACGGACA TTGCTGCCTT CGTGAAAGAG ATCTTGGGAG AGGACTCGTA A 1011

Domain Profile

S: 1     lekleelGaGnggvVekvlhkksgkilavKtirleikkeeqkqilrelevlkkssnspyi  60

         l +++elG+G++gvVekv+h +sg+i+avK+ir++++++eqk++l++l++ +++ ++ y+

Q: 53    LVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDCFYT  112

         56899*******************************************************

S: 61    vkfyGafvsegdvsicmelmdgtsldkvlkkvlekkkripekvlgkiavavvkaleylke  120

         v+fyGa+++egdv+icmelmd tsldk+++kvl+k+ +ipe++lg+iav++v+ale+l++

Q: 113   VTFYGALFREGDVWICMELMD-TSLDKFYRKVLDKNMTIPEDILGEIAVSIVRALEHLHS  171

         *********************.**************************************

S: 121   klkiiHRDvKPsNiLvnskGevKlCDFGvsgqlvdsiAksa.vGtksYmaPErieg...k  176

         kl++iHRDvKPsN+L+n++G+vK+CDFG+sg+lvds+Ak++ +G+k+YmaPEri++   +

Q: 172   KLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMdAGCKPYMAPERINPelnQ  231

         ********************************************************9999

S: 177   kkYsvksdvWslGltlvelatgrypyeklkeilellkaivneeppklpeeefseefqefv  236

         k Y+vksdvWslG+t++e+a+ r+pye++ +++++lk++v+e++p+lp+e+fs+ef++f

Q: 232   KGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPAEHFSPEFVDFT  291

         9***********************************************************

S: 237   skClkkdekeRpklkellkhafi  259

         ++Cl+k+++eR+++ el++h+f+

Q: 292   AQCLRKNPAERMSYLELMEHPFF  314

         *********************96

Domain Sequence
(FASTA)

LVTISELGRG AYGVVEKVRH AQSGTIMAVK RIRATVNSQE QKRLLMDLDI NMRTVDCFYT 60

VTFYGALFRE GDVWICMELM DTSLDKFYRK VLDKNMTIPE DILGEIAVSI VRALEHLHSK 120

LSVIHRDVKP SNVLINKEGH VKMCDFGISG YLVDSVAKTM DAGCKPYMAP ERINPELNQK 180

GYNVKSDVWS LGITMIEMAI LRFPYESWGT PFQQLKQVVE EPSPQLPAEH FSPEFVDFTA 240

QCLRKNPAER MSYLELMEHP FF 262

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013