EKS-OTG-00243

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-OTG-00243

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/PDK1	423.1	4.8E-127	85	345	261

Status

Unreviewed

Ensembl Protein

ENSOGAP00000004608

UniProt Accession

H0WRF5;

Protein Name

Protein Synonyms/Alias

Gene Name

PDPK1

Gene Synonyms/Alias

PDPK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000005147	ENSOGAP00000004608	ENSOGAT00000005152

Organism

Otolemur garnettii

Functional Description

Protein Length

559

Protein Sequence
(FASTA)

RAAGTEQKYD TVPIQSSVVL CSCPSPSMVR TQTESGTVPG IPGGGSSRQG PTMDGTTAES 60

RPSASSLQHA AQPALQPRKK RPEDFKFGKI LGEGSFSTVV LARELATSRE YAIKILEKRH 120

IIKENKVPYV TRERDVMSRL DHPFFVKLYF TFQDDEKLYF GLSYAKNGEL LKYIRKIGSF 180

DETCTRFYTA EIVSALEYLH GKGIIHRDLK PENILLNEDM HIQITDFGTA KVLSPESKQA 240

RANSFVGTAQ YVSPELLTEK SACKSSDLWA LGCIIYQLVA GLPPFRAGNE YLIFQKIIKL 300

EYDFPEKFFP KARDLVEKLL VLDATKRLGC EEMEGYAPLK AHPFFESITW ENLHQQTPPK 360

LTAYLPAMSE DDEDCYGNYD NLLSQFGCMQ VSSSSSSHSL SALDASLPQR SGSNIEQYIH 420

DLDTNSFELD LQFSEEEKRL LLEKQAGGNP WHQFVENNLI LKMGPVDKRK GLFARRRQLL 480

LTEGPHLYYV DPVNKVLKGE IPWSQELRPE AKNFKTFFVH TPNRTYYLMD PSGNAHKWCR 540

KIQEVWRQRY QSHPDAAVQ 559

Nucleotide Sequence
(FASTA)

AGGGCTGCAG GCACAGAGCA GAAGTATGAC ACCGTTCCTA TTCAGTCCAG TGTGGTATTA 60

TGTTCCTGCC CATCCCCATC AATGGTGAGG ACCCAGACTG AGTCTGGCAC GGTCCCTGGT 120

ATTCCTGGTG GTGGCAGTAG CAGGCAAGGC CCCACCATGG ATGGCACCAC AGCTGAATCC 180

CGACCAAGTG CCAGCTCCCT GCAACATGCT GCCCAGCCAG CACTGCAGCC TCGGAAGAAA 240

CGGCCGGAAG ACTTCAAGTT TGGGAAAATT CTTGGCGAAG GTTCTTTTTC GACAGTTGTA 300

CTGGCTCGAG AACTGGCAAC CTCCAGGGAA TATGCTATTA AAATTCTAGA GAAACGGCAT 360

ATTATAAAAG AGAACAAGGT CCCGTATGTA ACCAGAGAAC GAGATGTGAT GTCACGCCTG 420

GATCACCCCT TCTTTGTTAA GCTTTACTTC ACGTTTCAGG ATGATGAAAA GCTGTATTTT 480

GGCCTTAGTT ATGCCAAAAA TGGAGAACTA CTTAAATACA TTCGCAAAAT TGGTTCGTTT 540

GATGAGACCT GCACCCGATT CTACACAGCT GAGATTGTGT CTGCCCTGGA GTATCTGCAT 600

GGCAAGGGCA TCATTCACAG GGACCTTAAA CCAGAAAACA TTTTGTTAAA TGAAGATATG 660

CACATCCAGA TCACAGATTT TGGAACAGCA AAAGTATTAT CCCCAGAGAG CAAACAAGCC 720

AGGGCCAATT CATTCGTGGG AACAGCACAG TACGTTTCTC CAGAGCTGCT CACAGAGAAA 780

TCAGCTTGTA AAAGTTCAGA CCTTTGGGCT CTTGGATGCA TAATATACCA GCTTGTGGCA 840

GGACTCCCAC CATTCCGAGC CGGAAATGAA TATCTTATAT TTCAGAAGAT CATTAAATTG 900

GAATATGACT TTCCAGAGAA ATTCTTCCCT AAGGCAAGAG ACCTTGTGGA AAAACTTTTG 960

GTTTTAGATG CCACAAAGCG ATTAGGCTGT GAAGAAATGG AAGGGTATGC ACCTCTTAAA 1020

GCTCATCCAT TTTTTGAGTC CATAACATGG GAGAACCTAC ACCAGCAGAC TCCACCCAAG 1080

CTCACGGCTT ACTTACCAGC CATGTCGGAA GATGACGAGG ACTGCTATGG CAACTATGAC 1140

AATCTCCTGA GCCAGTTTGG CTGCATGCAA GTGTCATCGT CTTCCTCCTC CCACTCCTTG 1200

TCTGCCCTGG ATGCAAGTCT GCCCCAGAGG TCAGGCAGCA ACATAGAACA GTACATCCAC 1260

GATTTGGACA CTAATTCTTT TGAACTGGAC TTACAGTTTT CTGAAGAAGA GAAGAGGCTA 1320

TTATTGGAGA AGCAGGCTGG TGGAAACCCT TGGCATCAGT TTGTAGAAAA TAATTTAATA 1380

CTAAAAATGG GTCCAGTGGA TAAGCGAAAG GGTTTATTTG CACGACGACG ACAATTATTG 1440

CTCACAGAAG GGCCACATTT ATATTATGTG GATCCTGTCA ACAAAGTCCT GAAAGGTGAA 1500

ATTCCATGGT CACAAGAACT CCGACCAGAG GCCAAGAATT TTAAAACTTT CTTTGTTCAC 1560

ACGCCTAACA GGACGTATTA CCTGATGGAT CCAAGTGGGA ATGCTCACAA ATGGTGCAGA 1620

AAGATCCAGG AGGTTTGGAG GCAGCGATAC CAGAGCCACC CGGATGCTGC CGTGCAGTGA 1680

Domain Profile

S: 1     fkfekelgeGsystvvlarekeskkeyaikvlekryiikekkvkyvtrekevlaklnehp  60

         fkf+k+lgeGs+stvvlare+++++eyaik+lekr+iike+kv+yvtre++v+++l +hp

Q: 85    FKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRL-DHP  143

         89******************************************************.9**

S: 61    givkLyatfqDeeslyfvleyakkGdllellkkvgsfdeactryyaaellsaleflhkkg  120

         ++vkLy+tfqD+e+lyf l+yak+G+ll++++k+gsfde+ctr+y+ae++sale+lh kg

Q: 144   FFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKG  203

         ************************************************************

S: 121   iihrDlkpeniLldkdgkilitDfGsakvlepklkedskkeeeesarsksfvGtaeyvsP  180

         iihrDlkpeniLl++d++i+itDfG+akvl+p++k+         ar++sfvGta+yvsP

Q: 204   IIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQ---------ARANSFVGTAQYVSP  254

         ******************************999999.........9**************

S: 181   elLtdsevskssDlWalgcilyqllaGkpPfraeneylifkkilkleyafpegfpekakd  240

         elLt+++++kssDlWalgci+yql+aG+pPfra neylif+ki+kley+fpe+f++ka+d

Q: 255   ELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARD  314

         ************************************************************

S: 241   lveklLvkdakerltlee......ikahkff  265

         lveklLv da++rl++ee      +kah+ff

Q: 315   LVEKLLVLDATKRLGCEEmegyapLKAHPFF  345

         ******************************9

Domain Sequence
(FASTA)

FKFGKILGEG SFSTVVLARE LATSREYAIK ILEKRHIIKE NKVPYVTRER DVMSRLDHPF 60

FVKLYFTFQD DEKLYFGLSY AKNGELLKYI RKIGSFDETC TRFYTAEIVS ALEYLHGKGI 120

IHRDLKPENI LLNEDMHIQI TDFGTAKVLS PESKQARANS FVGTAQYVSP ELLTEKSACK 180

SSDLWALGCI IYQLVAGLPP FRAGNEYLIF QKIIKLEYDF PEKFFPKARD LVEKLLVLDA 240

TKRLGCEEME GYAPLKAHPF F 261

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR011993	; PH_like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013