EKS-OTG-00438

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-OTG-00438

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/ULK	361.0	3.8E-108	14	270	257

Status

Unreviewed

Ensembl Protein

ENSOGAP00000005006

UniProt Accession

H0WSE6;

Protein Name

Protein Synonyms/Alias

Gene Name

ULK3

Gene Synonyms/Alias

ULK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000005600	ENSOGAP00000005006	ENSOGAT00000005602

Organism

Otolemur garnettii

Functional Description

Protein Length

473

Protein Sequence
(FASTA)

MAGLGWGPPR LDGFILTERL GSGTYATVYK AYAKKDTREV VAIKCVAKKS LNKASVENLL 60

TEIEILKGIR HPHIVQLKDF QWDSDNIYLI MEFCAGGDLS RFIHTRRILP EKVARVFMQQ 120

LASALKFLHE RNISHLDLKP QNILLSSLEK PHLKLADFGF AQHMSPWDEK HVLRGSPLYM 180

APEMVCQGQY DARVDLWSVG VILYEALFGQ PPFASRSFSE LEEKIRSNRV IELPLRPLLS 240

RDCRDLLQRL LERDPSHRIS FQDFFVHPWV DLEHMPSGES LAKATALVVQ AVKKDQEGDA 300

ATALSLYCKA LDFFVPALHY EVDAQRKEAI KAKVGQYVSR AEELKTIVSS SNQALLRQGT 360

SARELLKEMA QDKPRLLAAL EVASAAMAKE EEAGREQDAL DLYQHSLGEL LLLLAAEPSG 420

RRRELLHTEQ VQNLMARAEY LKEQIKMKES RWEAETLDKE GLLESVRSSC TLQ 473

Nucleotide Sequence
(FASTA)

ATGGCGGGGC TGGGTTGGGG TCCCCCGCGC CTGGACGGCT TCATCCTCAC CGAGCGCCTG 60

GGCAGCGGCA CGTACGCCAC GGTGTACAAG GCCTACGCCA AGAAGGACAC TCGCGAGGTG 120

GTAGCCATCA AGTGTGTGGC CAAGAAAAGT CTGAACAAGG CATCAGTGGA AAACCTCCTG 180

ACCGAGATTG AGATCCTGAA GGGCATTCGA CACCCCCACA TCGTGCAGCT GAAAGACTTC 240

CAGTGGGACA GTGACAACAT CTACCTCATC ATGGAGTTCT GCGCAGGGGG TGACTTGTCA 300

CGCTTCATCC ACACCCGCAG GATTCTGCCT GAGAAGGTGG CTCGTGTCTT CATGCAACAA 360

TTGGCTAGTG CCCTGAAGTT TCTGCATGAA CGGAATATCT CTCACCTGGA TCTAAAGCCA 420

CAGAACATTC TGCTGAGCTC CTTGGAGAAG CCCCACCTGA AATTGGCAGA CTTTGGCTTT 480

GCGCAGCACA TGTCGCCCTG GGATGAAAAG CACGTGCTCC GTGGCTCCCC CCTCTACATG 540

GCCCCAGAGA TGGTGTGTCA GGGACAGTAC GACGCCCGTG TGGACCTCTG GTCTGTGGGG 600

GTCATCCTTT ATGAGGCCCT CTTCGGGCAG CCCCCCTTTG CCTCCAGGTC ATTCTCAGAG 660

CTGGAAGAGA AGATCCGCAG CAACCGGGTT ATAGAGCTCC CCCTGAGGCC TTTGCTCTCC 720

CGAGACTGCC GGGACCTGCT ACAGCGGCTC CTGGAGCGGG ACCCCAGCCA TCGCATCTCC 780

TTCCAAGACT TCTTTGTCCA CCCCTGGGTA GACCTAGAAC ACATGCCCAG TGGGGAGAGC 840

CTGGCAAAAG CAACTGCGCT GGTGGTGCAG GCTGTGAAGA AGGACCAAGA GGGGGATGCA 900

GCGACCGCCT TATCTCTCTA CTGCAAGGCT CTGGACTTCT TCGTGCCTGC CCTGCACTAT 960

GAAGTGGATG CCCAGCGGAA GGAGGCGATT AAGGCAAAGG TGGGGCAGTA CGTGTCCCGG 1020

GCTGAGGAGC TCAAGACCAT CGTTTCCTCC TCTAATCAGG CCCTGCTTAG GCAGGGGACA 1080

TCTGCCAGAG AGCTGCTTAA AGAGATGGCC CAGGACAAGC CACGCCTCCT AGCTGCCCTG 1140

GAAGTGGCTT CGGCTGCCAT GGCCAAGGAA GAGGAAGCTG GCCGGGAGCA GGATGCCCTG 1200

GACCTGTACC AGCATAGCCT AGGGGAGCTA CTGCTGCTGC TGGCAGCGGA GCCCTCAGGT 1260

CGGAGGCGGG AGCTGCTTCA TACTGAGCAG GTTCAGAACC TCATGGCTCG AGCTGAATAC 1320

CTGAAGGAGC AGATCAAGAT GAAGGAGTCT CGCTGGGAAG CAGAGACCCT GGATAAAGAG 1380

GGGCTGCTGG AGTCTGTTCG TAGTTCGTGT ACCCTGCAGT GA 1422

Domain Profile

S: 1     ysleeeiGkGsfavvykgrlrkktsqvvAikvvekkkl.kkslenlekeikilkelkhen  59

         ++l+e++G+G++a+vyk++++k+t++vvAik+v+kk+l k+s+enl +ei+ilk ++h++

Q: 14    FILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLnKASVENLLTEIEILKGIRHPH  73

         7899**********************************999*******************

S: 60    ivalldveetskevylvmeycaggdLakllkqkkeLsedtvreflqqlasalkaLhskki  119

         iv+l+d++++s+++yl+me+caggdL++++++++ L+e+++r+f+qqlasalk+Lh+++i

Q: 74    IVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLASALKFLHERNI  133

         ************************************************************

S: 120   vhrDlkPqniLlsyadakkelkkvtlkladFglarvlkeesmaatlkGsplYmaPEvvke  179

         +h DlkPqniLls      +l+k +lkladFg+a++++ +++++ l+GsplYmaPE+v++

Q: 134   SHLDLKPQNILLS------SLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYMAPEMVCQ  187

         *************......89***************************************

S: 180   qqydakaDlWSiGtilyellvGkpPfaaesiseLvekiekndvleppipkeisselkdll  239

          qyda++DlWS+G+ilye+l+G+pPfa++s+seL+eki++n+v+e+p++  +s++++dll

Q: 188   GQYDARVDLWSVGVILYEALFGQPPFASRSFSELEEKIRSNRVIELPLRPLLSRDCRDLL  247

         ************************************************************

S: 240   qsLLqrdpkkRisfeelfahpfl  262

         q+LL+rdp++Risf+++f hp++

Q: 248   QRLLERDPSHRISFQDFFVHPWV  270

         *********************96

Domain Sequence
(FASTA)

FILTERLGSG TYATVYKAYA KKDTREVVAI KCVAKKSLNK ASVENLLTEI EILKGIRHPH 60

IVQLKDFQWD SDNIYLIMEF CAGGDLSRFI HTRRILPEKV ARVFMQQLAS ALKFLHERNI 120

SHLDLKPQNI LLSSLEKPHL KLADFGFAQH MSPWDEKHVL RGSPLYMAPE MVCQGQYDAR 180

VDLWSVGVIL YEALFGQPPF ASRSFSELEE KIRSNRVIEL PLRPLLSRDC RDLLQRLLER 240

DPSHRISFQD FFVHPWV 257

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR007330	; MIT.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF04212	; MIT; 2.
PF00069	; Pkinase; 1.

SMARTs

SM00745	; MIT; 2.
SM00220	; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013