EPS-OTG-00015

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-OTG-00015

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/aDSP	67.8	8.5E-19	100	200	101

Status

Unreviewed

Ensembl Protein

ENSOGAP00000005364

UniProt Accession

H0WTA4;

Protein Name

Protein Synonyms/Alias

Gene Name

DUSP11

Gene Synonyms/Alias

DUSP11;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000005999	ENSOGAP00000005364	ENSOGAT00000006001

Organism

Otolemur garnettii

Functional Description

Protein Length

332

Protein Sequence
(FASTA)

MSQRHHARSG WGRGGDFSGR SSAKRKGGNH IPERWKDYIP VGQRMPGTRF IAFKVPLQKN 60

FKYTLTPEEC FSPLDLLNKI QEQNEELGLI IDLTYTQRYY KPEDLPETIP YLKIFTVGHQ 120

VPDDDTIFKF KCAVNGFLKE NKDNDKLIGV HCTHGLNRTG YLICRYLIDV EGMRPDDAIE 180

LFNRCRGHCL ERQNYIEDLQ NGPIRKSRNS SVYRSSGFQG SAHLKEPVHT MNKSVRQGPR 240

SNLHRTQGYP TPSQHFHTRT PNFQQSFRRF PQNQNVYQRG HIPPPGPPGE DYSQRRYSWN 300

ANSNAHQASQ NKRWYSDSYS RPSNPTYWGW TK 332

Nucleotide Sequence
(FASTA)

ATGAGCCAGC GGCATCATGC CCGCAGTGGC TGGGGCCGGG GAGGCGACTT TTCTGGACGC 60

TCCTCTGCCA AGAGGAAGGG CGGAAACCAC ATCCCGGAAA GGTGGAAAGA CTATATTCCA 120

GTTGGACAGC GGATGCCTGG GACTCGTTTC ATTGCTTTCA AAGTTCCTTT GCAAAAGAAT 180

TTTAAATACA CACTTACTCC AGAAGAATGC TTTTCCCCTT TGGATCTTTT AAACAAAATC 240

CAAGAACAAA ATGAAGAACT TGGACTGATA ATTGATTTAA CATACACTCA ACGCTATTAT 300

AAACCAGAGG ATTTGCCAGA AACTATTCCT TACTTAAAAA TTTTTACAGT TGGGCATCAG 360

GTGCCTGATG ATGACACTAT TTTTAAATTC AAATGTGCTG TTAATGGGTT TTTGAAGGAA 420

AATAAAGATA ATGACAAGCT TATTGGTGTC CACTGTACTC ATGGTTTAAA CAGGACTGGC 480

TACCTAATCT GTAGATATTT GATTGATGTA GAAGGCATGA GGCCAGATGA TGCAATTGAA 540

TTATTCAATA GGTGCCGGGG ACACTGCTTA GAAAGACAGA ACTACATTGA AGACCTTCAG 600

AATGGTCCTA TCAGAAAGAG TCGGAATTCC AGTGTGTACA GGTCAAGTGG ATTTCAAGGC 660

TCAGCACATC TCAAGGAACC AGTCCACACA ATGAATAAAT CTGTTAGACA AGGCCCTAGG 720

TCTAACCTAC ATCGGACCCA AGGTTACCCA ACTCCTTCTC AGCATTTCCA CACCCGGACC 780

CCAAATTTTC AACAGTCATT CAGGAGATTT CCACAGAATC AGAATGTTTA CCAGAGAGGC 840

CATATCCCTC CTCCTGGTCC CCCAGGAGAG GACTATTCAC AAAGGAGATA CTCTTGGAAT 900

GCGAATTCAA ATGCCCATCA AGCATCTCAG AATAAAAGGT GGTATTCTGA CAGCTATAGC 960

AGACCATCCA ATCCAACCTA TTGGGGATGG ACCAAGTGA 999

Domain Profile

S: 39    ikvqviPeylikkgityknipvdDsdvtdllqyfdeaaefideakekggkvlvHCaaGvs  98

          k +  Pe +   +i  ++ +v D+d   ++++  +++ f++e+k++++ + vHC++G++

Q: 100   YKPEDLPETIPYLKIFTVGHQVPDDD--TIFKFKCAVNGFLKENKDNDKLIGVHCTHGLN  157

         44455555555555554555555554..599*****************************

S: 99    RSatlvlaYLmkveglslsdAieavkrkrpsiepnegfleQLl  141

         R+++l++ YL++veg++ +dAie ++r+r+++ ++++++e L

Q: 158   RTGYLICRYLIDVEGMRPDDAIELFNRCRGHCLERQNYIEDLQ  200

         ***************************************9986

Domain Sequence
(FASTA)

YKPEDLPETI PYLKIFTVGH QVPDDDTIFK FKCAVNGFLK ENKDNDKLIG VHCTHGLNRT 60

GYLICRYLID VEGMRPDDAI ELFNRCRGHC LERQNYIEDL Q 101

Keyword

Complete proteome; Hydrolase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Taeniopygia guttata"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0004725	; F:protein tyrosine phosphatase activity
GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0035335	; P:peptidyl-tyrosine dephosphorylation

KEGG

InterPros

IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR000387	; Tyr/Dual-specificity_Pase.
IPR016130	; Tyr_Pase_AS.

Pfam

PF00782

; DSPc; 1.

SMARTs

Prosites

PS00383	; TYR_PHOSPHATASE_1; 1.
PS50056	; TYR_PHOSPHATASE_2; 1.

Prints

Created Date

20-Feb-2013