EKS-OTG-00262

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-OTG-00262

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	237.7	1.2E-70	49	314	266

Status

Unreviewed

Ensembl Protein

ENSOGAP00000006336

UniProt Accession

H0WVJ2;

Protein Name

Protein Synonyms/Alias

Gene Name

STK11

Gene Synonyms/Alias

STK11;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000007076	ENSOGAP00000006336	ENSOGAT00000007079

Organism

Otolemur garnettii

Functional Description

Protein Length

442

Protein Sequence
(FASTA)

MDVVDPQQLG VFSEGELISV GMDTFIHRID STEVIYQPRR KRAKLIGKYL MGDLLGEGSY 60

GKVKEVLDSE TLCRRAVKIL KKKKLRRIPN GEANVKKEIQ LLRRLRHKNV IQLVDVLYNE 120

EKQKHLTYMV MEYCVCGMQE MLDSVPEKRF PVCQAHGYFC QLIDGLEYLH SQGIVHKDIK 180

PGNLLLTTSG TLKISDLGVA EALHPFAVDD TCRTSQGSPA FQPPEIANGL DTFSGFKVDI 240

WSAGVTLKRS YNITTGLYPF EGDNIYKLFE NIGKGSYAIP GDCGPPLSDL LKGMLEYEPT 300

KRFSIRQIRQ HSWFRKKHPP AEAPVPIPPS PDTKDRWRSM TVVPYLEDLH GSAEDEDEDL 360

FDIEDDIIYT QDFTVPGQVP EEEASQNGQN QGLPKAVCMN GTESAQLNTK PKVECRAGAP 420

NPARRAYSTS SKIRRLSACK QQ 442

Nucleotide Sequence
(FASTA)

ATGGATGTGG TGGACCCGCA GCAGTTGGGC GTGTTCTCTG AGGGCGAGCT GATTTCGGTG 60

GGCATGGACA CGTTTATCCA CCGTATAGAC TCCACGGAGG TTATCTACCA GCCTCGCCGC 120

AAGCGGGCCA AGCTCATCGG CAAGTACTTG ATGGGGGACC TTCTGGGGGA AGGCTCCTAT 180

GGCAAGGTGA AGGAGGTGCT AGACTCAGAG ACGCTGTGCC GGAGGGCGGT CAAGATCCTC 240

AAGAAGAAGA AGTTGCGTAG GATCCCCAAC GGGGAGGCGA ACGTGAAGAA GGAAATTCAA 300

CTACTGAGGA GGCTACGGCA CAAAAATGTT ATTCAACTGG TAGATGTGTT GTACAACGAG 360

GAGAAGCAGA AACACCTCAC GTATATGGTG ATGGAGTACT GCGTGTGCGG CATGCAGGAG 420

ATGCTGGACA GTGTGCCCGA GAAGCGCTTC CCTGTGTGCC AGGCCCATGG GTACTTCTGC 480

CAGCTCATTG ATGGCCTGGA GTACCTGCAT AGCCAGGGTA TTGTGCACAA GGACATTAAG 540

CCAGGCAACC TGCTGCTTAC CACCAGTGGC ACTCTCAAGA TATCTGACCT GGGTGTGGCT 600

GAGGCTCTGC ACCCATTTGC TGTGGATGAC ACTTGCCGGA CCAGCCAGGG CTCCCCAGCA 660

TTTCAGCCAC CTGAGATTGC CAACGGTCTA GACACCTTCT CAGGCTTCAA GGTGGACATC 720

TGGTCGGCAG GGGTCACACT GAAACGAAGC TACAACATCA CCACGGGCCT GTATCCATTC 780

GAAGGCGACA ACATCTACAA ACTGTTTGAG AACATCGGGA AGGGGAGCTA TGCCATCCCA 840

GGCGACTGTG GTCCCCCACT CTCTGACCTG CTGAAAGGCA TGCTTGAGTA TGAGCCCACG 900

AAGAGGTTCT CCATACGGCA GATCCGGCAG CACAGCTGGT TTCGGAAGAA GCACCCACCA 960

GCTGAGGCGC CAGTGCCCAT CCCGCCCAGC CCAGACACCA AGGACCGGTG GCGTAGCATG 1020

ACGGTGGTGC CATACCTAGA AGACCTGCAT GGTAGTGCCG AGGACGAGGA TGAGGACCTC 1080

TTTGACATTG AGGATGACAT CATTTATACT CAGGATTTTA CAGTGCCCGG ACAGGTCCCG 1140

GAAGAAGAGG CCAGTCAGAA TGGACAGAAC CAGGGCCTGC CCAAGGCTGT GTGCATGAAC 1200

GGCACGGAGT CAGCACAGCT GAACACCAAA CCCAAGGTGG AGTGCCGGGC TGGGGCCCCC 1260

AACCCTGCCC GCAGGGCCTA CTCCACCAGC AGCAAGATCC GCCGGCTGTC AGCTTGCAAA 1320

CAACAGTGA 1329

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkkl..seeslekikrEieilkklkhp  58

         y +++ lGegs+gkVk++ ++et  + avKi+kkkkl    +   ++k+Ei++l++l+h+

Q: 49    YLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLrrIPNGEANVKKEIQLLRRLRHK  108

         778999******************************965334567***************

S: 59    niikllevi....etkkklylvleyasgg..eLfdyieekgrlkekearklfkqlvsavk  112

         n+i+l++v+    ++k+ +y+v+ey+  g  e++d +  ++r++  +a+ +f ql+++++

Q: 109   NVIQLVDVLyneeKQKHLTYMVMEYCVCGmqEMLDSV-PEKRFPVCQAHGYFCQLIDGLE  167

         ********96643344558******998888*****6.8899******************

S: 113   YlhskgivHrDlKpeNllldkkenikiaDFGlan...lfkegklletfcGsppYaaPell  169

         Ylhs+givH+D+Kp Nlll++++++ki+D+G+a+    f  +++++t++Gsp++++Pe+

Q: 168   YLHSQGIVHKDIKPGNLLLTTSGTLKISDLGVAEalhPFAVDDTCRTSQGSPAFQPPEIA  227

         *********************************955556778******************

S: 170   kg.kkYegpkvDvWslGvvL...yalvtgklPfdeenlkellekilkgkleipkklskel  225

         +g ++++g kvD+Ws+Gv+L   y++ tg +Pf+++n+ +l+e+i kg++ ip  + + l

Q: 228   NGlDTFSGFKVDIWSAGVTLkrsYNITTGLYPFEGDNIYKLFENIGKGSYAIPGDCGPPL  287

         99899***************9999************************************

S: 226   esLlrklLvvdpekRatieeilkhewl  252

         ++Ll+ +L+ +p+kR++i++i++h+w+

Q: 288   SDLLKGMLEYEPTKRFSIRQIRQHSWF  314

         **************************7

Domain Sequence
(FASTA)

YLMGDLLGEG SYGKVKEVLD SETLCRRAVK ILKKKKLRRI PNGEANVKKE IQLLRRLRHK 60

NVIQLVDVLY NEEKQKHLTY MVMEYCVCGM QEMLDSVPEK RFPVCQAHGY FCQLIDGLEY 120

LHSQGIVHKD IKPGNLLLTT SGTLKISDLG VAEALHPFAV DDTCRTSQGS PAFQPPEIAN 180

GLDTFSGFKV DIWSAGVTLK RSYNITTGLY PFEGDNIYKL FENIGKGSYA IPGDCGPPLS 240

DLLKGMLEYE PTKRFSIRQI RQHSWF 266

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013