EKS-OTG-00427

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-OTG-00427

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/SGK	529.5	1.7E-159	35	292	258

Status

Unreviewed

Ensembl Protein

ENSOGAP00000006886

UniProt Accession

H0WWV1;

Protein Name

Protein Synonyms/Alias

Gene Name

SGK2

Gene Synonyms/Alias

SGK2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000007695	ENSOGAP00000006886	ENSOGAT00000007700

Organism

Otolemur garnettii

Functional Description

Protein Length

367

Protein Sequence
(FASTA)

MDSSPAGAPS PQPSRANGNV HLGPSANPNA RPTDFDFLKV IGKGNYGKVL LAKHKTDGMF 60

YAVKVLQKKS ILKRKEQGHI MAERNVLLKN VRHPFLVGLR YSFQTPEKLY FVLDYVNGGE 120

LFFHLQRERR FLEPRARFYA AEVASAIGYL HSLNIIYRDL KPENILLDCQ GHIVLTDFGL 180

CKEGVEPEET TSTFCGTPEY LAPEVLRKEP YDRAVDWWCL GAVLYEMLQG LPPFYSQDVA 240

QMYDNILHQP LQIPGGRTVA ACDLLQGLLH KDQRQRLGSK ADFLEIKNHV FFSPINWDDL 300

YHKRLTPPFN PNVEGPADLK HFDPEFTQEA VSKSIGCTPD AVASSSGASS AFLGFSYAQE 360

DNDLLDC 367

Nucleotide Sequence
(FASTA)

ATGGACTCTA GCCCGGCCGG GGCCCCCAGT CCACAGCCCT CCAGGGCCAA TGGGAACGTC 60

CACCTGGGAC CTTCAGCCAA CCCAAACGCC AGGCCCACGG ACTTCGACTT TCTCAAAGTC 120

ATTGGCAAGG GGAACTACGG GAAGGTCCTC CTGGCCAAAC ACAAGACAGA CGGCATGTTC 180

TATGCAGTGA AGGTGCTGCA GAAAAAATCC ATCCTAAAGA GGAAAGAGCA GGGACACATC 240

ATGGCAGAGC GCAATGTGCT TCTGAAGAAT GTGAGGCACC CCTTCCTGGT AGGCCTGCGC 300

TACTCCTTCC AGACTCCCGA GAAGCTCTAC TTCGTGCTCG ATTATGTCAA CGGGGGAGAG 360

CTCTTCTTCC ACCTGCAGCG AGAGCGCCGG TTCCTGGAGC CTCGGGCCCG CTTCTACGCT 420

GCAGAGGTGG CCAGCGCCAT TGGCTACCTA CACTCCCTCA ACATCATTTA CAGGGACCTG 480

AAACCAGAAA ACATTCTCTT GGACTGCCAG GGACACATAG TACTGACAGA TTTCGGCCTC 540

TGCAAGGAAG GTGTCGAGCC CGAGGAGACC ACATCCACGT TCTGTGGCAC CCCTGAGTAC 600

TTGGCTCCCG AAGTGCTTCG GAAAGAGCCT TATGACCGCG CAGTGGACTG GTGGTGCTTG 660

GGGGCAGTCC TCTACGAGAT GCTACAGGGC CTGCCACCCT TCTACAGCCA AGATGTGGCC 720

CAGATGTATG ACAACATTCT ACACCAGCCG CTGCAGATCC CTGGGGGCCG GACAGTGGCT 780

GCCTGCGACC TCCTGCAGGG CCTTCTCCAT AAGGACCAGA GGCAGCGGCT GGGCTCCAAA 840

GCAGACTTCC TTGAGATAAA GAATCATGTA TTCTTCAGCC CCATAAACTG GGATGACTTG 900

TACCACAAGA GGCTGACTCC ACCTTTCAAC CCCAATGTGG AAGGACCTGC TGACCTGAAA 960

CACTTTGACC CAGAGTTCAC CCAGGAAGCT GTGTCCAAGT CCATCGGCTG CACCCCTGAC 1020

GCTGTGGCCA GCAGCTCTGG GGCCTCAAGC GCATTTCTGG GATTTTCTTA TGCGCAGGAG 1080

GATAATGACC TCTTGGATTG CTAG 1104

Domain Profile

S: 1     fdflkvigkgsfgkvllakrkadekfyavkvlqkkailkkkeekhimaernvllknvkhp  60

         fdflkvigkg++gkvllak+k+d+ fyavkvlqkk+ilk+ke+ himaernvllknv+hp

Q: 35    FDFLKVIGKGNYGKVLLAKHKTDGMFYAVKVLQKKSILKRKEQGHIMAERNVLLKNVRHP  94

         9***********************************************************

S: 61    flvglhysfqtaeklyfvldyvnggelffhlqrersfleprarfyaaeiasalgylhsln  120

         flvgl+ysfqt+eklyfvldyvnggelffhlqrer+fleprarfyaae+asa+gylhsln

Q: 95    FLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSLN  154

         ************************************************************

S: 121   ivyrdlkpenilldskghvvltdfglckeeieaedttstfcgtpeylapevlrkkpydrt  180

         i+yrdlkpenilld++gh+vltdfglcke++e e+ttstfcgtpeylapevlrk+pydr+

Q: 155   IIYRDLKPENILLDCQGHIVLTDFGLCKEGVEPEETTSTFCGTPEYLAPEVLRKEPYDRA  214

         ************************************************************

S: 181   vdwwclgavlyemlyglppfysrdvaemydnilnkplqlkpgisvaalelleellekdrk  240

         vdwwclgavlyeml glppfys+dva+mydnil++plq+++g++vaa++ll++ll+kd++

Q: 215   VDWWCLGAVLYEMLQGLPPFYSQDVAQMYDNILHQPLQIPGGRTVAACDLLQGLLHKDQR  274

         ************************************************************

S: 241   krlgakedfleiknhvff  258

         +rlg+k+dfleiknhvff

Q: 275   QRLGSKADFLEIKNHVFF  292

         *****************9

Domain Sequence
(FASTA)

FDFLKVIGKG NYGKVLLAKH KTDGMFYAVK VLQKKSILKR KEQGHIMAER NVLLKNVRHP 60

FLVGLRYSFQ TPEKLYFVLD YVNGGELFFH LQRERRFLEP RARFYAAEVA SAIGYLHSLN 120

IIYRDLKPEN ILLDCQGHIV LTDFGLCKEG VEPEETTSTF CGTPEYLAPE VLRKEPYDRA 180

VDWWCLGAVL YEMLQGLPPF YSQDVAQMYD NILHQPLQIP GGRTVAACDL LQGLLHKDQR 240

QRLGSKADFL EIKNHVFF 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xenopus tropicalis"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013