EKS-OTG-00205

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-OTG-00205

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/RCK	473.8	1.8E-142	4	290	287

Status

Unreviewed

Ensembl Protein

ENSOGAP00000007049

UniProt Accession

H0WX85;

Protein Name

Protein Synonyms/Alias

Gene Name

ICK

Gene Synonyms/Alias

ICK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000007868	ENSOGAP00000007049	ENSOGAT00000007873

Organism

Otolemur garnettii

Functional Description

Protein Length

638

Protein Sequence
(FASTA)

MNRYTTIKQL GDGTYGSVLL GRSIESGELI AIKKMKRKFY SWEECMNLRE VKSLKKLNHA 60

NVVKLKEVIR ENDHLYFIFE YMKENLYQLI KERRRQIFPT KVCRSFSLYH IAVRIDGICF 120

FHKEDSFFHR DLKPENLLCM GPDLVKIADF GLAREIRSRP PYTDYVSTRW YRAPEVLLRS 180

TNYSSPIDVW AVGCIMAEVY TLRPLFPGAS EIDTIFKICQ VLGTPKKTDW PEGYQLSNAM 240

NFRWPQCVPN NLKTLIPNAS SEAIQLLRDM LQWDPKKRPT ASQALRYPYF QVGHPLGSTT 300

QNLQDSGKTQ KDILEKAGPP PHIKPAPPTQ PPAKPHTRIS SRQHQASQPP QHLMCPYKAE 360

ASRTDHLSQL QEDKSSSLLF PSVHSKNPQT KILANLEHKN GDMKPKSRRR WGLISRSSKD 420

SEDWADLEDF DFSPSLTRID LKNKKRQSED ALCRFESVLD LKPSEPVGTG SSAPTQPSHQ 480

RRDTPTLRSA AKQHYLKHSR YLPGINIRNG ILSNPGKDFI PPNPWSSSGL SGKSSGTVSV 540

ISKINSVGSG STSSSGLTGN YIPSFLKKEI GSAMQRVHLA PIPNPSPGYS SLKAMRPHPG 600

RPFFHTQPRS TPGLIPRPPA AQPVHGRTDW ASKYASRR 638

Nucleotide Sequence
(FASTA)

ATGAATAGGT ACACGACGAT CAAGCAGCTG GGGGATGGGA CTTATGGTTC CGTCCTGCTG 60

GGAAGGAGCA TTGAGTCCGG GGAACTGATC GCTATTAAAA AAATGAAAAG AAAGTTTTAT 120

TCCTGGGAGG AATGCATGAA TCTCCGGGAG GTTAAGTCTT TAAAGAAGCT CAACCATGCC 180

AATGTAGTCA AATTAAAAGA AGTTATCAGG GAAAATGATC ATCTATATTT TATCTTCGAG 240

TACATGAAGG AAAATCTTTA CCAGCTTATT AAAGAAAGGA GACGGCAAAT TTTCCCCACT 300

AAAGTTTGTA GAAGTTTTAG TTTATATCAT ATAGCAGTAA GAATAGATGG TATCTGTTTC 360

TTTCATAAAG AAGACAGCTT CTTCCACCGG GACTTAAAGC CTGAGAACCT CCTCTGCATG 420

GGCCCAGACC TTGTGAAAAT TGCAGACTTT GGATTGGCCC GAGAAATCCG ATCGAGACCG 480

CCATACACAG ACTATGTATC TACCAGATGG TACAGGGCTC CAGAAGTCCT CCTGAGGTCT 540

ACCAACTACA GCTCCCCCAT TGACGTCTGG GCCGTGGGCT GCATCATGGC AGAAGTTTAT 600

ACCCTCAGGC CGCTCTTCCC TGGGGCCAGT GAGATTGACA CGATATTCAA AATTTGCCAA 660

GTGTTGGGGA CACCAAAAAA GACTGACTGG CCTGAAGGCT ATCAACTGTC AAATGCTATG 720

AACTTCCGCT GGCCCCAGTG TGTACCCAAT AACTTAAAGA CTCTGATTCC CAATGCCAGC 780

AGCGAGGCAA TTCAGCTCCT GAGAGACATG CTGCAGTGGG ACCCGAAGAA GCGACCAACA 840

GCTAGTCAGG CACTTCGATA CCCTTATTTC CAGGTTGGAC ACCCACTGGG CAGCACCACA 900

CAGAATCTTC AGGATTCAGG GAAAACACAA AAAGACATCC TGGAAAAGGC AGGCCCGCCT 960

CCTCATATTA AGCCAGCCCC TCCTACCCAG CCCCCAGCCA AGCCCCACAC ACGGATTTCT 1020

TCACGACAGC ATCAAGCCAG TCAGCCCCCT CAGCATCTCA TGTGCCCCTA CAAAGCAGAA 1080

GCGTCCAGGA CAGATCACCT GAGCCAGCTC CAGGAGGACA AGTCCAGCTC ATTGCTTTTC 1140

CCATCTGTCC ACAGTAAGAA TCCCCAGACG AAGATCCTCG CTAACCTGGA GCACAAAAAC 1200

GGTGACATGA AGCCAAAGAG CAGGAGAAGG TGGGGTCTCA TTTCCAGGTC ATCAAAGGAT 1260

TCCGAAGATT GGGCTGACTT GGAGGATTTC GATTTCAGTC CGTCCCTCAC CAGGATTGAC 1320

CTGAAAAACA AGAAGAGACA GAGCGAGGAC GCTCTCTGCA GGTTTGAGAG TGTTTTGGAC 1380

CTGAAGCCCT CTGAGCCCGT GGGCACAGGA AGCAGCGCGC CCACCCAGCC TTCACACCAG 1440

AGGCGGGACA CACCCACCCT GAGGTCCGCC GCCAAGCAGC ACTACTTGAA GCATTCTCGA 1500

TACTTGCCTG GAATAAATAT AAGAAATGGA ATACTCTCCA ATCCAGGCAA GGACTTTATA 1560

CCACCTAATC CGTGGTCTAG TTCTGGTTTG TCTGGAAAAT CTTCAGGGAC AGTATCAGTA 1620

ATCAGCAAGA TAAATTCAGT TGGTTCTGGC TCTACAAGTT CTAGTGGACT GACTGGAAAC 1680

TATATCCCTT CCTTCCTGAA AAAAGAAATT GGTTCTGCTA TGCAGAGAGT ACACCTGGCG 1740

CCTATTCCAA ATCCTTCCCC TGGTTATTCT TCCCTGAAGG CCATGAGACC TCATCCTGGG 1800

CGACCTTTCT TCCACACGCA GCCTAGAAGC ACTCCTGGGT TGATACCACG GCCACCAGCT 1860

GCCCAGCCAG TGCATGGCCG GACAGACTGG GCTTCCAAGT ACGCGTCTCG GCGGTGA 1917

Domain Profile

S: 1     yklikklGdGtfgevllakslktgelvaikkmkrkfesleevtnlrevkslkklnahdni  60

         y++ik+lGdGt+g+vll++s+++gel+aikkmkrkf+s+ee++nlrevkslkkln h+n+

Q: 4     YTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLN-HANV  62

         99*****************************************************.****

S: 61    iklkeviidrendslylvlelmeenlyqlikd.rrkllsesklksi.lyqi...lkglaf  115

         +klkevi  rend+ly+++e+m+enlyqlik+ rr++++ ++ +s+ ly i   + g+ f

Q: 63    VKLKEVI--RENDHLYFIFEYMKENLYQLIKErRRQIFPTKVCRSFsLYHIavrIDGICF  120

         *******..***********************77789*****999658888444579999

S: 116   ihkh.gffhrdlkPenilikgselvkladfGlarevrsknPytdyvstrwyraPevllrs  174

          hk+ +ffhrdlkPen+l++g++lvk+adfGlare+rs++PytdyvstrwyraPevllrs

Q: 121   FHKEdSFFHRDLKPENLLCMGPDLVKIADFGLAREIRSRPPYTDYVSTRWYRAPEVLLRS  180

         9*8627******************************************************

S: 175   gvysspldlwavGcvlaevavlrplfPGaseidqifkilevlGtPkkkewdeayklasal  234

         ++yssp+d+wavGc++aev++lrplfPGaseid+ifki++vlGtPkk++w+e+y+l++a+

Q: 181   TNYSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSNAM  240

         ************************************************************

S: 235   nlkfpqvegsslktlvsnaskealellkdllaydPderataqqalkypyf  284

         n+++pq+++++lktl++nas+ea++ll+d+l++dP++r+ta+qal+ypyf

Q: 241   NFRWPQCVPNNLKTLIPNASSEAIQLLRDMLQWDPKKRPTASQALRYPYF  290

         *************************************************9

Domain Sequence
(FASTA)

YTTIKQLGDG TYGSVLLGRS IESGELIAIK KMKRKFYSWE ECMNLREVKS LKKLNHANVV 60

KLKEVIREND HLYFIFEYMK ENLYQLIKER RRQIFPTKVC RSFSLYHIAV RIDGICFFHK 120

EDSFFHRDLK PENLLCMGPD LVKIADFGLA REIRSRPPYT DYVSTRWYRA PEVLLRSTNY 180

SSPIDVWAVG CIMAEVYTLR PLFPGASEID TIFKICQVLG TPKKTDWPEG YQLSNAMNFR 240

WPQCVPNNLK TLIPNASSEA IQLLRDMLQW DPKKRPTASQ ALRYPYF 287

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013