EKS-OTG-00343

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-OTG-00343

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/PEK	403.5	4.8E-121	591	1076	486

Status

Unreviewed

Ensembl Protein

ENSOGAP00000007377

UniProt Accession

H0WY15;

Protein Name

Protein Synonyms/Alias

Gene Name

EIF2AK3

Gene Synonyms/Alias

EIF2AK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000008231	ENSOGAP00000007377	ENSOGAT00000008243

Organism

Otolemur garnettii

Functional Description

Protein Length

1115

Protein Sequence
(FASTA)

MERAIRRGLL ARALLLWLLL ELAAETVAAG RARDPSGPMA EAAFGLGAAA APTSAARVPA 60

AGAVVAAEVT VEDAEALPAA AGEQDRWGPE PNDEAELRPR SRSLVIISTL DGRIAALDPE 120

NHGKKQWDLD VGSGSLVSSS LSKPEVFGNK MIIPSLDGDL FQWDRDRESM ETVPFTVESL 180

LESSYKFGDD VVLVGGKSLT TYGLSAYSGK VRYICSAVGC RQWDSDEMEQ EDILLLQRTQ 240

KTVRAVGPRS GNEKWNFSVG HFELRYIPDM ETRAGFIEST FKPSDNKEES RIISDVEEQE 300

AAMMDTVIKV SVADWKVMAF SKKGGHLEWE YQFCTPIASA WLVKDGKVIP ISLFDDTSYT 360

SNDDVLEDEE DIVEAARGAT ENSVYLGMYR GQLYLQSSVR ISEKFPSSPK ALESVNNENA 420

IIPLPTIKWK PLIHSPSRTP VLVGSDEFDK CLSNDKFSHE EYSNGALSIL QYPYDNGYYL 480

PYYKRERNKR STQITVRFLN NPTYNKNIRK KDPVLLLHWW KEIIGTILFC IIATTFIVRR 540

LFHPHPHRQR KESETQCQTE NKYDSVSGEA NDSNWNDIKN SGYISRYLTD FEPIQCMGRG 600

GFGVVFEARN KVDDCNYAIK RIRLPNSREL AREKVMREVK ALAKLEHPGI VRYFNAWLEA 660

PPEKWQEKMD EIWLKDESTD WQLSSPTPTD APSVKICRMD PFSPKEHIEI IAPSPQRSRS 720

FSVGISCGQT SSSESQFSPL EFSGMDHEDI SESEDVAYNL QDSCLTDCDS EDGTMDGNDE 780

GHSFELCPSE ASPDVRSRER TSSSIVFEDS GCDNASSKEE PKTNRLHVGN HYANKLTAVK 840

HTNTKSSSEA TLSISPPRPT TLSLDLTKNT TEKLQPSSPK VYLYIQMQLC RKENLKDWMN 900

RRCTIEERER SVCLHIFLQI AEAVEFLHSK GLMHRDLKPS NIFFTMDDVV KVGDFGLVTA 960

MDQDEEEQTV LTPMPAYARH TGQVGTKLYM SPEQIHGNSY SHKVDIFSLG LILFELLYPF 1020

STQMERVRTL TDVRNLKFPP LFTQKYPREY VMVQDMLSPS PMERPEATNI IENAVFEDLE 1080

FPEKTVLRQR SRSLSSSGTK HSRQSSNPHS PLPSN 1115

Nucleotide Sequence
(FASTA)

ATGGAGCGCG CCATCCGCCG GGGGTTGCTA GCGCGGGCGC TGCTGCTGTG GCTGCTGCTG 60

GAGCTCGCCG CCGAGACGGT GGCCGCGGGG CGTGCCCGCG ACCCTTCAGG GCCGATGGCG 120

GAGGCGGCCT TTGGTCTGGG GGCAGCGGCT GCTCCCACCT CTGCGGCGCG GGTGCCGGCG 180

GCAGGAGCCG TGGTTGCGGC TGAGGTAACG GTGGAGGACG CTGAGGCGCT GCCGGCGGCC 240

GCGGGCGAGC AGGACCGGTG GGGGCCAGAA CCCAACGACG AGGCCGAGCT GCGGCCGCGC 300

AGCAGGTCAT TAGTAATCAT CAGCACTTTA GATGGGCGAA TTGCTGCCTT GGATCCAGAA 360

AATCATGGGA AAAAGCAATG GGACTTGGAC GTGGGATCTG GCTCCTTGGT TTCCTCTAGC 420

CTTAGCAAAC CAGAGGTATT TGGGAACAAG ATGATTATTC CTTCCCTGGA TGGAGACCTG 480

TTCCAGTGGG ACCGAGACCG TGAGAGCATG GAAACAGTTC CTTTCACAGT TGAATCACTT 540

CTTGAATCTT CTTATAAATT TGGAGATGAT GTTGTTTTGG TTGGAGGAAA ATCTCTCACT 600

ACCTATGGAC TCAGTGCATA TAGTGGGAAG GTGAGGTACA TCTGTTCAGC TGTGGGTTGT 660

CGCCAGTGGG ATAGTGATGA AATGGAACAA GAAGACATAC TCCTTCTGCA ACGCACCCAG 720

AAAACTGTGA GAGCTGTTGG ACCTCGTAGC GGCAATGAGA AGTGGAATTT CAGTGTTGGC 780

CACTTTGAAC TTCGGTATAT TCCAGACATG GAAACTAGAG CCGGATTTAT TGAAAGCACC 840

TTTAAGCCCA GTGATAACAA AGAAGAGTCT AGAATTATTT CAGATGTGGA AGAACAGGAA 900

GCAGCCATGA TGGACACAGT GATAAAGGTC TCAGTTGCTG ATTGGAAGGT CATGGCGTTC 960

AGTAAGAAGG GAGGACATCT GGAATGGGAG TACCAGTTTT GTACTCCAAT TGCATCTGCC 1020

TGGTTAGTTA AGGATGGGAA AGTCATTCCC ATCAGTCTTT TTGATGATAC AAGTTATACA 1080

TCTAATGATG ACGTTTTAGA AGATGAAGAA GACATTGTAG AAGCTGCCCG GGGAGCCACA 1140

GAAAACAGCG TTTACTTGGG AATGTATCGA GGTCAGCTGT ATCTTCAGTC ATCGGTCAGA 1200

ATTTCAGAAA AATTTCCTTC AAGTCCCAAG GCCTTGGAAT CTGTCAATAA TGAGAATGCT 1260

ATTATTCCTT TGCCAACAAT CAAATGGAAA CCCTTAATTC ATTCTCCTTC CAGAACTCCA 1320

GTCTTGGTGG GATCTGATGA ATTTGACAAA TGTCTTAGTA ATGATAAGTT TTCCCATGAA 1380

GAATACAGTA ATGGTGCACT TTCAATCCTG CAGTATCCGT ATGACAATGG TTATTATCTA 1440

CCATACTACA AGAGAGAAAG AAACAAACGG AGCACACAGA TCACTGTCAG ATTCCTCAAC 1500

AACCCAACTT ACAACAAGAA TATCCGCAAG AAGGATCCTG TTCTTCTCTT ACACTGGTGG 1560

AAAGAAATAA TTGGAACAAT TTTATTTTGT ATCATAGCAA CAACTTTTAT TGTGCGCAGA 1620

CTTTTTCATC CTCATCCTCA CAGACAAAGG AAAGAGTCTG AAACTCAGTG TCAAACTGAA 1680

AATAAATATG ATTCTGTAAG TGGTGAAGCC AATGACAGTA ACTGGAATGA CATAAAAAAC 1740

TCCGGATATA TATCACGCTA TCTAACAGAT TTTGAACCAA TTCAATGCAT GGGTCGTGGT 1800

GGCTTTGGAG TTGTCTTTGA AGCTAGAAAC AAAGTAGATG ACTGCAATTA TGCTATCAAG 1860

AGGATCCGTC TACCCAATAG CAGAGAATTG GCTCGGGAGA AGGTAATGCG AGAAGTGAAA 1920

GCTTTGGCCA AGCTGGAACA TCCAGGAATT GTTAGATATT TCAATGCCTG GCTGGAAGCA 1980

CCACCAGAGA AGTGGCAAGA AAAGATGGAT GAAATTTGGC TGAAAGATGA AAGCACAGAC 2040

TGGCAACTCA GCTCTCCCAC CCCAACAGAT GCACCGTCAG TTAAAATATG CAGAATGGAT 2100

CCTTTCTCTC CAAAAGAACA TATTGAAATC ATAGCTCCTT CACCACAAAG AAGCAGATCT 2160

TTTTCAGTAG GAATTTCCTG TGGCCAGACA AGTTCATCTG AGAGCCAGTT CTCTCCTCTG 2220

GAATTCTCAG GAATGGACCA TGAAGATATC AGTGAGTCAG AGGATGTAGC ATACAACCTC 2280

CAAGACAGTT GCCTTACAGA CTGTGATTCG GAAGATGGTA CTATGGATGG CAATGATGAG 2340

GGGCACTCCT TTGAACTCTG TCCTTCTGAA GCTTCTCCTG ACGTAAGGTC CAGGGAGAGA 2400

ACCTCCTCTT CCATTGTATT TGAAGACTCT GGCTGTGATA ATGCATCCAG TAAAGAAGAG 2460

CCCAAAACTA ACCGACTGCA TGTCGGCAAC CATTATGCTA ATAAACTAAC TGCTGTTAAG 2520

CACACCAATA CCAAATCTTC TTCTGAAGCT ACTTTGTCTA TTTCTCCTCC AAGACCAACC 2580

ACTTTAAGTT TAGACCTCAC CAAAAACACC ACGGAAAAAC TCCAGCCCAG TTCACCGAAG 2640

GTGTACCTTT ATATTCAGAT GCAGCTGTGC AGAAAGGAAA ACCTCAAGGA CTGGATGAAC 2700

CGGCGATGCA CCATAGAGGA GAGAGAGAGG AGCGTGTGTC TGCACATCTT CCTGCAGATC 2760

GCAGAGGCCG TGGAGTTTCT GCACAGTAAA GGACTTATGC ACAGGGACCT CAAGCCTTCG 2820

AACATATTCT TTACAATGGA TGATGTGGTC AAGGTTGGAG ACTTTGGATT AGTGACTGCA 2880

ATGGACCAGG ATGAGGAAGA ACAGACAGTT CTGACACCAA TGCCTGCTTA TGCCAGACAC 2940

ACAGGACAAG TAGGGACCAA ACTGTACATG AGCCCAGAGC AGATTCATGG AAACAGCTAT 3000

TCTCATAAAG TGGACATCTT TTCTTTAGGC CTAATTCTAT TTGAATTGCT GTACCCATTC 3060

AGCACTCAGA TGGAGAGAGT CAGGACCCTC ACTGATGTAA GAAATCTCAA ATTTCCACCA 3120

CTGTTTACTC AGAAATATCC TCGTGAGTAT GTGATGGTTC AAGACATGCT CTCTCCATCC 3180

CCAATGGAAC GGCCAGAAGC TACAAACATC ATTGAAAATG CTGTATTTGA GGACTTGGAG 3240

TTTCCAGAAA AAACAGTGCT CAGACAGAGG TCTCGCTCTC TGAGTTCATC AGGAACAAAA 3300

CATTCAAGAC AGTCTAGCAA CCCCCATAGT CCTTTGCCAA GCAATTAG 3348

Domain Profile

S: 1     feeikvlGkGgfgvVlkaknkldkkeyaikriklnkakke.lekverevkaLaklehpni  59

         fe i+++G+GgfgvV++a+nk+d+++yaikri+l++  +  +ekv+revkaLaklehp+i

Q: 591   FEPIQCMGRGGFGVVFEARNKVDDCNYAIKRIRLPNSRELaREKVMREVKALAKLEHPGI  650

         799*******************************9877666*******************

S: 60    vrYfaawleekeesl.............................................  74

         vrYf+awle ++e++

Q: 651   VRYFNAWLEAPPEKWqekmdeiwlkdestdwqlssptptdapsvkicrmdpfspkehiei  710

         ************************************************************

S: 75    ............................................................  74

Q: 711   iapspqrsrsfsvgiscgqtsssesqfsplefsgmdhedisesedvaynlqdscltdcds  770

         ************************************************************

S: 75    ...td.sseveaeaeleesesseesdtk................................  98

            t+ ++++ +++el++se+s++++++

Q: 771   edgTMdGNDEGHSFELCPSEASPDVRSRertsssivfedsgcdnasskeepktnrlhvgn  830

         **966699999999999999999999999999****************************

S: 99    ...................................................llyiqmelc  107

                                                            +lyiqm+lc

Q: 831   hyankltavkhtntkssseatlsispprpttlsldltkntteklqpsspkvYLYIQMQLC  890

         ************************************************************

S: 108   eketLkdwiderkllesrselvm.rlfkqllegleylHskgliHrdLkpsniFldsddqv  166

         +ke+Lkdw+++r+++e+r++ v+ ++f q++e++e+lHskgl+HrdLkpsniF+++dd v

Q: 891   RKENLKDWMNRRCTIEERERSVClHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTMDDVV  950

         ************************************************************

S: 167   KigDFgLatalaealkedvkqdaqskeakhtgqvgtklymsPeqleksqYnkkvDifsLG  226

         K+gDFgL+ta++++++e+++ ++++++a+htgqvgtklymsPeq+++++Y++kvDifsLG

Q: 951   KVGDFGLVTAMDQDEEEQTVLTPMPAYARHTGQVGTKLYMSPEQIHGNSYSHKVDIFSLG  1010

         ************************************************************

S: 227   lilfeLlypfstemervetltelrdgkipedfddkvpkekkllqkllsrdpkeRpsasel  286

         lilfeLlypfst+merv+tlt++r++k+p  f++k+p e+ ++q++ls +p+eRp+a+++

Q: 1011  LILFELLYPFSTQMERVRTLTDVRNLKFPPLFTQKYPREYVMVQDMLSPSPMERPEATNI  1070

         ************************************************************

S: 287   lksell  292

         ++++++

Q: 1071  IENAVF  1076

         **9875

Domain Sequence
(FASTA)

FEPIQCMGRG GFGVVFEARN KVDDCNYAIK RIRLPNSREL AREKVMREVK ALAKLEHPGI 60

VRYFNAWLEA PPEKWQEKMD EIWLKDESTD WQLSSPTPTD APSVKICRMD PFSPKEHIEI 120

IAPSPQRSRS FSVGISCGQT SSSESQFSPL EFSGMDHEDI SESEDVAYNL QDSCLTDCDS 180

EDGTMDGNDE GHSFELCPSE ASPDVRSRER TSSSIVFEDS GCDNASSKEE PKTNRLHVGN 240

HYANKLTAVK HTNTKSSSEA TLSISPPRPT TLSLDLTKNT TEKLQPSSPK VYLYIQMQLC 300

RKENLKDWMN RRCTIEERER SVCLHIFLQI AEAVEFLHSK GLMHRDLKPS NIFFTMDDVV 360

KVGDFGLVTA MDQDEEEQTV LTPMPAYARH TGQVGTKLYM SPEQIHGNSY SHKVDIFSLG 420

LILFELLYPF STQMERVRTL TDVRNLKFPP LFTQKYPREY VMVQDMLSPS PMERPEATNI 480

IENAVF 486

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>