EKS-OTG-00426

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-OTG-00426

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/SGK	540.4	7.5E-163	98	355	258

Status

Unreviewed

Ensembl Protein

ENSOGAP00000007830

UniProt Accession

H0WZ40;

Protein Name

Protein Synonyms/Alias

Gene Name

SGK1

Gene Synonyms/Alias

SGK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000008732	ENSOGAP00000007830	ENSOGAT00000008736

Organism

Otolemur garnettii

Functional Description

Protein Length

432

Protein Sequence
(FASTA)

MTVKTEAARG PLTYSRMRGM VAILIAFMKQ RRMGLNDFIQ KIANNSYACK HPEVQSILKI 60

SQPQEPELMN ANPSPPPSPS QQINLGPSSN PHAKPSDFHF LKVIGKGSFG KVLLARHKAE 120

EVFYAVKVLQ KKAILKKKEE KHIMSERNVL LKNVKHPFLV GLHFSFQTAD KLYFVLDYIN 180

GGELFYHLQR ERCFLEPRAR FYAAEIASAL GYLHSLNIVY RDLKPENILL DSQGHIVLTD 240

FGLCKENIEH NGTTSTFCGT PEYLAPEVLH KQPYDRTVDW WCLGAVLYEM LYGLPPFYSR 300

NTAEMYDNIL NKPLQLKPNI TNSARHLLEG LLQKDRTKRL GAKDDFMEIK SHVFFSLINW 360

DDLINKKITP PFNPNVQSGP SDLRHFDPEF TEEPVPNSIG RSPDSILITA SVKEAAEAFL 420

GFSYAPPMDS FL 432

Nucleotide Sequence
(FASTA)

ATGACGGTGA AAACTGAGGC TGCTAGGGGT CCCCTCACTT ACTCCAGAAT GAGGGGAATG 60

GTAGCGATTC TTATCGCTTT CATGAAACAG AGGAGGATGG GCCTGAACGA CTTTATTCAG 120

AAGATTGCTA ATAACTCCTA CGCATGCAAG CACCCAGAAG TTCAGTCCAT CTTGAAAATC 180

TCCCAGCCCC AGGAGCCTGA GCTTATGAAC GCCAACCCTT CTCCTCCACC AAGTCCTTCT 240

CAACAAATCA ACCTTGGTCC CTCATCCAAC CCTCATGCTA AACCATCTGA CTTTCACTTC 300

TTGAAAGTGA TTGGGAAAGG CAGTTTTGGA AAGGTTCTTC TAGCAAGACA CAAGGCAGAA 360

GAAGTGTTCT ATGCAGTCAA AGTTTTACAG AAGAAAGCAA TCCTGAAAAA GAAGGAGGAG 420

AAGCATATTA TGTCAGAGCG CAATGTTTTA TTGAAGAATG TGAAACACCC TTTCCTGGTG 480

GGCCTTCACT TCTCTTTCCA GACTGCAGAC AAATTGTACT TTGTCCTAGA CTACATTAAT 540

GGTGGCGAGT TGTTCTACCA TCTCCAGAGG GAGCGCTGCT TCCTGGAACC ACGGGCTCGT 600

TTCTATGCTG CTGAAATAGC CAGTGCCTTG GGTTACCTGC ACTCTCTGAA CATCGTCTAC 660

AGAGACTTAA AACCAGAGAA TATCCTGCTA GACTCCCAGG GACACATTGT CCTTACTGAC 720

TTTGGACTGT GCAAGGAAAA CATTGAGCAC AATGGCACGA CGTCTACCTT CTGTGGTACA 780

CCTGAGTATC TGGCACCTGA GGTGCTCCAT AAGCAGCCTT ATGACCGGAC TGTGGACTGG 840

TGGTGCCTGG GGGCCGTCTT GTATGAGATG CTGTATGGCC TGCCTCCTTT TTATAGCCGA 900

AACACAGCTG AGATGTACGA CAACATTCTG AACAAGCCCC TCCAGTTGAA ACCAAATATC 960

ACCAATTCTG CAAGGCACCT CCTGGAAGGC CTCCTGCAGA AGGACAGGAC AAAGCGGCTC 1020

GGTGCCAAGG ATGACTTTAT GGAGATTAAG AGTCATGTCT TCTTCTCCCT AATTAACTGG 1080

GATGATCTCA TTAATAAGAA GATTACTCCT CCTTTTAACC CAAATGTGCA GAGTGGACCC 1140

AGCGACCTGC GGCACTTTGA TCCCGAGTTT ACCGAAGAGC CGGTCCCCAA CTCCATCGGC 1200

AGGTCCCCCG ACAGCATCCT CATCACGGCC AGCGTCAAGG AAGCTGCGGA GGCTTTCCTG 1260

GGCTTCTCCT ACGCACCTCC CATGGACTCC TTCCTCTGA 1299

Domain Profile

S: 1     fdflkvigkgsfgkvllakrkadekfyavkvlqkkailkkkeekhimaernvllknvkhp  60

         f+flkvigkgsfgkvlla++ka+e+fyavkvlqkkailkkkeekhim+ernvllknvkhp

Q: 98    FHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHP  157

         9***********************************************************

S: 61    flvglhysfqtaeklyfvldyvnggelffhlqrersfleprarfyaaeiasalgylhsln  120

         flvglh+sfqta+klyfvldy+nggelf+hlqrer+fleprarfyaaeiasalgylhsln

Q: 158   FLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLN  217

         ************************************************************

S: 121   ivyrdlkpenilldskghvvltdfglckeeieaedttstfcgtpeylapevlrkkpydrt  180

         ivyrdlkpenillds+gh+vltdfglcke+ie++ ttstfcgtpeylapevl+k+pydrt

Q: 218   IVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVLHKQPYDRT  277

         ************************************************************

S: 181   vdwwclgavlyemlyglppfysrdvaemydnilnkplqlkpgisvaalelleellekdrk  240

         vdwwclgavlyemlyglppfysr++aemydnilnkplqlkp+i+++a++lle+ll+kdr+

Q: 278   VDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRT  337

         ************************************************************

S: 241   krlgakedfleiknhvff  258

         krlgak+df+eik+hvff

Q: 338   KRLGAKDDFMEIKSHVFF  355

         *****************9

Domain Sequence
(FASTA)

FHFLKVIGKG SFGKVLLARH KAEEVFYAVK VLQKKAILKK KEEKHIMSER NVLLKNVKHP 60

FLVGLHFSFQ TADKLYFVLD YINGGELFYH LQRERCFLEP RARFYAAEIA SALGYLHSLN 120

IVYRDLKPEN ILLDSQGHIV LTDFGLCKEN IEHNGTTSTF CGTPEYLAPE VLHKQPYDRT 180

VDWWCLGAVL YEMLYGLPPF YSRNTAEMYD NILNKPLQLK PNITNSARHL LEGLLQKDRT 240

KRLGAKDDFM EIKSHVFF 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013