EKS-OTG-00291

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-OTG-00291

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	346.1	1.5E-103	236	526	291

Status

Unreviewed

Ensembl Protein

ENSOGAP00000009633

UniProt Accession

H0X3D9;

Protein Name

Protein Synonyms/Alias

Gene Name

BMPR1A

Gene Synonyms/Alias

BMPR1A;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000010762	ENSOGAP00000009633	ENSOGAT00000010766

Organism

Otolemur garnettii

Functional Description

Protein Length

537

Protein Sequence
(FASTA)

LTENYNETIS FSEMIYLQIP YLNAGQNLDS MLHGTGMKSD SDQKKSENGV TLAPEDTLPF 60

LKCYCSGHCP DDAINNTCIT NGHCFAIIEE DDQGETTLAS GCMKYEGSDF QCKDSPKAQL 120

RRTIECCRTN LCNQYLQPTL PPVVIGPFFD GSIRWLVLLI SMSVCIIAMI IFSSCFCYKH 180

YCKSISSRRR YNRDLEQDEA FIPVGESLKD LIDQSQSSGS GSGLPLLVQR TIAKQIQMVR 240

QVGKGRYGEV WMGKWRGEKV AVKVFFTTEE ASWFRETEIY QTVLMRHENI LGFIAADIKG 300

TGSWTQLYLI TDYHENGSLY DFLKCATLDT RALLKLAYST ACGLCHLHTE IYGTQGKPAI 360

AHRDLKSKNI LIKKNGSCCI ADLGLAVKFN STVYFIDLFL SVGSGTCQIY VHLVLDTFTS 420

FSYIQYYPLF SVNNSGGCNH YFCAHCVLPL PTGIVEEYQL PYYNMVPSDP SYEDMREVVC 480

VKRLRPLVSN RWNSDECLRA VLKLMSECWA HNPASRLTAL RIKKTLAKMV ESQDVKI 537

Nucleotide Sequence
(FASTA)

CTCACTGAAA ATTATAATGA AACAATTAGC TTTTCAGAAA TGATTTACTT ACAAATTCCA 60

TATTTAAATG CAGGGCAGAA TCTAGACAGT ATGCTCCATG GCACTGGGAT GAAATCAGAC 120

TCCGATCAGA AAAAGTCAGA AAATGGAGTA ACCTTAGCAC CGGAGGATAC TTTGCCTTTT 180

TTAAAGTGCT ACTGCTCAGG ACACTGCCCA GATGATGCTA TTAATAACAC ATGCATAACT 240

AATGGACATT GCTTTGCCAT CATAGAAGAA GATGACCAGG GAGAAACCAC ATTAGCTTCA 300

GGGTGTATGA AATATGAAGG ATCTGATTTT CAGTGCAAGG ATTCACCAAA AGCCCAGCTA 360

CGCCGGACAA TAGAATGTTG TCGGACCAAT TTATGTAACC AATATTTGCA ACCCACACTG 420

CCCCCTGTTG TTATAGGTCC ATTTTTTGAT GGCAGCATTC GATGGCTGGT TTTGCTCATT 480

TCTATGTCTG TCTGCATAAT TGCTATGATC ATCTTCTCCA GCTGCTTTTG TTACAAACAT 540

TATTGCAAGA GTATCTCTAG CAGACGTCGT TATAATCGTG ATTTGGAACA AGATGAAGCA 600

TTTATTCCAG TTGGAGAATC ATTAAAAGAC CTTATTGACC AGTCACAGAG TTCTGGTAGT 660

GGATCTGGAC TGCCATTATT GGTTCAGCGA ACTATTGCCA AACAGATCCA GATGGTTCGG 720

CAAGTTGGTA AAGGACGATA TGGAGAAGTG TGGATGGGCA AATGGCGTGG TGAAAAAGTG 780

GCAGTGAAGG TATTCTTTAC CACGGAAGAA GCTAGCTGGT TTCGAGAAAC AGAAATCTAC 840

CAAACTGTGC TAATGCGCCA TGAAAACATA CTTGGTTTCA TAGCAGCGGA CATTAAAGGT 900

ACAGGTTCCT GGACTCAGCT CTATTTGATT ACTGATTACC ATGAAAATGG ATCTCTTTAT 960

GACTTCCTGA AATGTGCTAC ACTAGACACC AGAGCCCTGC TCAAGTTGGC TTATTCAACT 1020

GCCTGTGGTC TGTGCCACCT TCACACAGAA ATTTATGGCA CTCAAGGAAA GCCTGCAATT 1080

GCTCATCGAG ACCTAAAGAG CAAAAACATC CTCATCAAGA AAAATGGAAG TTGCTGTATT 1140

GCTGACCTGG GCCTTGCTGT TAAATTCAAC AGTACAGTCT ATTTTATTGA TCTCTTTTTG 1200

AGCGTAGGTT CCGGGACCTG CCAGATCTAT GTTCACTTGG TCTTGGACAC ATTTACCAGT 1260

TTTTCTTATA TTCAGTACTA TCCTCTTTTC TCAGTCAACA ACAGTGGCGG CTGCAACCAT 1320

TATTTTTGTG CCCACTGTGT TCTGCCACTC CCTACAGGGA TAGTAGAAGA GTACCAATTG 1380

CCATACTACA ACATGGTACC CAGCGATCCA TCCTATGAAG ATATGCGTGA GGTTGTGTGT 1440

GTCAAACGTT TGCGGCCACT TGTGTCTAAT CGATGGAACA GTGATGAATG TCTGCGAGCA 1500

GTTTTAAAGC TAATGTCAGA ATGCTGGGCC CACAATCCAG CTTCCAGACT TACAGCATTG 1560

AGAATCAAGA AGACACTTGC CAAGATGGTT GAATCCCAAG ACGTAAAGAT CTGA 1614

Domain Profile

S: 1     lklleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenilqfia  60

         +++++++gkGrygeVw++k+rge+vAvK+f+t++easw+rE+eiyqtvl+rhenil+fia

Q: 236   IQMVRQVGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIA  295

         799*********************************************************

S: 61    adkkeedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgtk  120

         ad+k ++s+t+l+l+t+yhe+gsL+d+Lk  tld++ ll+la+s+a+Gl+hLH+ei gt+

Q: 296   ADIKGTGSWTQLYLITDYHENGSLYDFLKCATLDTRALLKLAYSTACGLCHLHTEIYGTQ  355

         ************************************************************

S: 121   gkkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekeeldlaansqvGtkRYmaPE  180

         g  KpaiaHRDlkskNil+kk+++cciaDlGLa+k++++   +dl  ++  Gt

Q: 356   G--KPAIAHRDLKSKNILIKKNGSCCIADLGLAVKFNSTVYFIDLFLSVGSGTCQIYVHL  413

         *..****************************************************9999*

S: 181   vleealnlkdfeafkraDvYslgLvlWEvasRcee..vdeeveeyklpfeevvgsdPsle  238

         vl+  + ++ ++ +    v   g      +  c    ++++veey+lp++++v+sdPs+e

Q: 414   VLDTFTSFSYIQYYPLFSVNNSGGCNHYFCAHCVLplPTGIVEEYQLPYYNMVPSDPSYE  473

         *********************************99999**********************

S: 239   emkevvvekklrPkipeawkkkealkelsklleecWdadpeaRltalrvkkrl  291

         +m+evv++k+lrP ++++w+++e+l+++ kl++ecW+++p++Rltalr+kk+l

Q: 474   DMREVVCVKRLRPLVSNRWNSDECLRAVLKLMSECWAHNPASRLTALRIKKTL  526

         ***************************************************97

Domain Sequence
(FASTA)

IQMVRQVGKG RYGEVWMGKW RGEKVAVKVF FTTEEASWFR ETEIYQTVLM RHENILGFIA 60

ADIKGTGSWT QLYLITDYHE NGSLYDFLKC ATLDTRALLK LAYSTACGLC HLHTEIYGTQ 120

GKPAIAHRDL KSKNILIKKN GSCCIADLGL AVKFNSTVYF IDLFLSVGSG TCQIYVHLVL 180

DTFTSFSYIQ YYPLFSVNNS GGCNHYFCAH CVLPLPTGIV EEYQLPYYNM VPSDPSYEDM 240

REVVCVKRLR PLVSNRWNSD ECLRAVLKLM SECWAHNPAS RLTALRIKKT L 291

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0005524	; F:ATP binding
GO:0005024	; F:transforming growth factor beta-activated receptor activity
GO:0007178	; P:transmembrane receptor protein serine/threonine kinase signaling pathway

KEGG

InterPros

IPR000472	; Activin_rcpt.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.
IPR003605	; TGF_beta_rcpt_GS.

Pfam

PF01064	; Activin_recp; 1.
PF00069	; Pkinase; 1.
PF08515	; TGF_beta_GS; 1.

SMARTs

SM00467

; GS; 1.

Prosites

PS51256	; GS; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013