EKS-OTG-00306

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-OTG-00306

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/EGFR	186.0	8.0E-55	579	690	112

Status

Unreviewed

Ensembl Protein

ENSOGAP00000009637

UniProt Accession

H0X3E3;

Protein Name

Protein Synonyms/Alias

Gene Name

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000010768	ENSOGAP00000009637	ENSOGAT00000010772

Organism

Otolemur garnettii

Functional Description

Protein Length

690

Protein Sequence
(FASTA)

TEILNGGVYV DQNKFLCYAD TIHWQDIVRN PWPSNLTLVS TNGSSGCGRC HKSCTGRCWG 60

PTESHCQTLT RTVCAEQCDG RCYGPYVSDC CHRECAGGCS GPKDTDCFVC IGIHISNSLK 120

RNTEISFIFF PSQISSKQTF RVKVTYVQFI MKLCRYNFVV DSSSCVRACP SSKMEVEENG 180

IKMCKPCTDI CPKACDGIGT GSLLSAQTVD SSNIDKFINC TKINGNLIFL VTGIHGDPYN 240

AIEAIDPEKL NVFRTVREIT GFLNIQSWPP NMTDFSVFSN LVTIGGRVLY SGLSLLILKQ 300

QGITSLQFQS LKEISAGNIY ITDNSNLCYY HTINWTTLFS TINQRIVIRD NRKAENCTAE 360

GMVCNHLCSN DGCWGSGPDQ CLSCRRFSRG RVCIESCNLY DGEFREFENG SICVECDPQC 420

EKMEDGVLTC HGPGPDNCTK CSHFKDGPNC VEKCPDGLQG ANSFIFKYAD QDRECHPCHP 480

NCTQGCNGPT SHDCIYYPWT GHSTLPQHAR TPLIAAGVIG GLFILVIVGL TFAVYVRRKS 540

IKKKRALRRF LETELVEPLT PSGTAPNQAQ LRILKETELK RVKVLGSGAF GTVYKGIWVP 600

EGETVKIPVA IKILNETTGP KANVEFMDEA LIMASMDHPH LVRLLGVCLS PTIQLVTQLM 660

PHGCLLEYVH EHKDNIGSQL LLNWCVQIAK 690

Nucleotide Sequence
(FASTA)

ACAGAAATCC TAAATGGTGG AGTCTATGTA GATCAGAACA AATTCCTTTG TTATGCAGAC 60

ACCATTCATT GGCAAGATAT TGTCCGGAAC CCATGGCCTT CCAACTTGAC TCTGGTGTCA 120

ACAAATGGTA GCTCAGGATG TGGACGTTGC CATAAGTCTT GTACCGGCCG ATGCTGGGGA 180

CCCACAGAAA GCCATTGCCA GACTTTGACA AGGACAGTGT GTGCAGAACA ATGTGATGGC 240

AGATGCTACG GACCCTACGT CAGTGACTGC TGCCACAGAG AATGTGCTGG AGGCTGCTCA 300

GGACCTAAGG ACACAGACTG CTTTGTATGT ATTGGAATAC ATATAAGCAA TTCTTTAAAA 360

AGGAACACAG AAATTTCTTT TATATTTTTT CCTTCTCAAA TATCTAGCAA ACAAACATTC 420

AGAGTAAAAG TAACATATGT ACAATTTATT ATGAAATTAT GTAGGTATAA CTTTGTGGTA 480

GATTCCAGTT CTTGTGTGCG TGCCTGCCCT AGTTCCAAGA TGGAAGTCGA AGAAAATGGG 540

ATTAAAATGT GTAAACCTTG CACTGATATT TGCCCGAAAG CTTGTGATGG CATTGGCACG 600

GGATCGCTGC TGTCGGCTCA GACAGTGGAC TCCAGTAACA TCGACAAATT CATAAACTGC 660

ACCAAGATCA ATGGGAATTT GATCTTCCTT GTCACTGGTA TTCATGGGGA CCCTTACAAT 720

GCAATTGAAG CCATAGACCC AGAGAAACTG AACGTCTTTC GGACAGTCAG AGAGATAACA 780

GGTTTCTTGA ACATACAGTC ATGGCCCCCA AATATGACCG ACTTCAGCGT TTTTTCTAAC 840

CTGGTGACCA TTGGTGGAAG AGTGCTCTAC AGTGGCCTCT CCTTGCTCAT CCTCAAGCAA 900

CAGGGCATCA CCTCTCTGCA GTTCCAGTCC CTGAAGGAAA TCAGTGCAGG AAACATCTAC 960

ATTACCGACA ACAGCAACCT GTGTTATTAT CATACCATTA ACTGGACAAC TCTCTTCAGC 1020

ACGATCAACC AAAGAATCGT AATCCGGGAC AACAGGAAAG CAGAAAATTG TACTGCTGAA 1080

GGAATGGTGT GCAACCATCT GTGTTCCAAT GATGGCTGTT GGGGTTCTGG GCCAGACCAG 1140

TGTCTCTCCT GCCGCCGCTT CAGCCGGGGA AGGGTCTGCA TAGAGTCTTG TAACCTCTAT 1200

GACGGTGAAT TTCGGGAGTT TGAGAACGGC TCCATCTGTG TGGAGTGTGA TCCCCAGTGT 1260

GAGAAAATGG AAGATGGCGT CCTCACCTGC CATGGACCGG GACCTGACAA CTGTACAAAG 1320

TGTTCTCATT TTAAGGATGG CCCAAACTGT GTGGAAAAAT GTCCAGATGG CTTACAGGGG 1380

GCAAACAGTT TCATTTTCAA GTACGCCGAT CAGGATCGAG AGTGCCACCC GTGCCATCCA 1440

AACTGCACCC AGGGGTGTAA CGGTCCCACT AGTCATGACT GCATTTACTA CCCATGGACG 1500

GGCCATTCCA CTTTACCACA ACATGCTAGA ACTCCACTGA TTGCGGCCGG GGTCATTGGA 1560

GGGCTCTTCA TCCTGGTCAT TGTGGGTCTG ACGTTTGCAG TTTATGTCAG AAGGAAGAGT 1620

ATCAAGAAGA AAAGAGCCTT GAGGAGATTC CTGGAAACAG AGCTGGTAGA ACCCTTAACC 1680

CCCAGTGGCA CAGCACCCAA TCAAGCTCAG CTTCGCATTT TGAAAGAAAC TGAGCTGAAG 1740

AGGGTCAAAG TCCTTGGCTC AGGTGCCTTT GGAACCGTTT ATAAAGGTAT TTGGGTGCCT 1800

GAAGGAGAAA CAGTGAAGAT TCCTGTAGCT ATTAAGATTC TTAATGAGAC GACTGGTCCC 1860

AAGGCCAACG TGGAGTTCAT GGATGAAGCT CTGATTATGG CAAGTATGGA CCATCCACAT 1920

TTAGTCCGGT TACTAGGTGT GTGTCTGAGT CCAACCATCC AGCTGGTGAC TCAGCTCATG 1980

CCCCATGGCT GCCTACTGGA GTACGTCCAC GAGCACAAGG ATAACATCGG ATCACAGCTG 2040

CTGCTGAACT GGTGTGTCCA GATAGCGAAG 2070

Domain Profile

S: 1     lkklkvlGsGafGtvykGiwipegenvkipvaikvleektgkkankelldealvlasldh  60

         lk++kvlGsGafGtvykGiw+pege+vkipvaik+l+e+tg+kan e++deal++as+dh

Q: 579   LKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDH  638

         699*********************************************************

S: 61    anlvrllglclsstlqlvtqllplGclldyvrehkdklGsqellnwcvqiak  112

         ++lvrllg+cls t+qlvtql+p+Gcll+yv+ehkd++Gsq llnwcvqiak

Q: 639   PHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAK  690

         ***************************************************8

Domain Sequence
(FASTA)

LKRVKVLGSG AFGTVYKGIW VPEGETVKIP VAIKILNETT GPKANVEFMD EALIMASMDH 60

PHLVRLLGVC LSPTIQLVTQ LMPHGCLLEY VHEHKDNIGS QLLLNWCVQI AK 112

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Danio rerio"; ?>Equus caballus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0005524	; F:ATP binding
GO:0004714	; F:transmembrane receptor protein tyrosine kinase activity
GO:0007169	; P:transmembrane receptor protein tyrosine kinase signaling pathway

KEGG

InterPros

IPR000494	; EGF_rcpt_L.
IPR006211	; Furin-like_Cys-rich_dom.
IPR006212	; Furin_repeat.
IPR009030	; Growth_fac_rcpt.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.

Pfam

PF00757	; Furin-like; 1.
PF07714	; Pkinase_Tyr; 1.
PF01030	; Recep_L_domain; 1.

SMARTs

SM00261

; FU; 5.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013